Papers by Marco Romanelli
Journal of the American Academy of Dermatology, 2013
Livedoid vasculopathy (LV) is a noninflammatory thrombotic condition presenting in a primary idio... more Livedoid vasculopathy (LV) is a noninflammatory thrombotic condition presenting in a primary idiopathic or secondary subtype associated with abnormal coagulation factors. Different from atrophie blanche (AB), which is a clinical manifestation of certain scars, LV may have AB in combination with recurrent livedo reticularis with chronic and painful skin ulcers particularly around the ankle region, and at the back of the feet. Histology is characterized by segmental hyalinizing changes at the subintimal region of small dermal vessels with thrombotic occlusions. LV skin ulcers resolve with stellate, porcelain-white scars that need to be distinguished from similar changes seen with venous insufficiency. ''Atrophie blanche'' was originally used synonymously with ''livedoid vasculopathy.'' AB describes spontaneously occurring porcelain-white skin areas with red dots that typically occur in the context of skin changes attributed to chronic venous insufficiency. The 2 forms of ABe(1) the LV-AB complex and (2) AB in the context of chronic venous insufficiencyeare unrelated and require separate diagnostic and therapeutic approaches. Using a modified Delphi method, we have developed an international consensus document on the diagnosis and management of LV. Individual sections of this document provide advice on diagnosis and management of LV. ( J Am
BioMed Research International, 2014
The development of civilization leads to many chronic diseases. Of the health problems specific t... more The development of civilization leads to many chronic diseases. Of the health problems specific to frail both young and older people, unhealed chronic wounds (venous and pressure ulcers and diabetic foot), cancer-related lymphedema, and urinary incontinence are the major health disorders, and the establishment and spread of effective treatment methods for the following health problems are a pressing issue. The described disorders are a common and costly problem in nursing home settings, with the prevalence of estimates varying widely from 17 to even 53%.
Seismological Research Letters, 2015
Nursing, 2004
Time heals all wounds, it is said. The effects of chronic victimisation have not yet been conside... more Time heals all wounds, it is said. The effects of chronic victimisation have not yet been considered fully in the literature on repeat victimisation. This chapter presents evidence to suggest that the emotional scars of chronic victimisation can be so deep that everyday life loses meaning. It loses meaning because life itself -the freedom and ability to live as one wishes, the ability to function normally -is itself lost. The emotional processes are so traumatic that they resemble bereavement. ...you fear it can always happen and you know it's beyond your control and so if it's beyond your control the fear's always there and it doesn't go away. [Male chronic victim] Crime Prevention Studies, volume 12,
Nella presente relazione si descrive l'attivit a svolta durante l'anno 2010 dall'Isti... more Nella presente relazione si descrive l'attivit a svolta durante l'anno 2010 dall'Istituto Nazionale di Oceanografia e di Geofisica SperimentaleOGS per conto della Direzione Regionale per la Protezione Civile (DRPC) della Regione Autonoma Friuli-Venezia Giulia (FVG) nell'ambito della Convenzione n. 58 del 19/02/2008 .
Journal of Wound Care, 2008
To compare an ibuprofen-releasing foam dressing (Biatain Ibu, ColoplastA/S) with local best pract... more To compare an ibuprofen-releasing foam dressing (Biatain Ibu, ColoplastA/S) with local best practice in the treatment of painful exuding wounds. In this large-scale randomised comparative study, 853 patients were randomised to either ibuprofen-releasing foam (test) dressing (n=467) or local best practice (n=386). Primary endpoint was wound pain relief from day 1-7, assessed by the patients twice daily using a five-point verbal rating scale. Secondary endpoints were reduction in pain intensity from day 0-7 (assessed using an 11-point numeric box scale), quality of life (assessed using the WHO-5 well-being index and effect on health-related activities of daily living) and the incidence of adverse events. After seven days significantly more patients in the experimental group experienced relief from temporary and persistent pain and a reduction in pain intensity,when compared with patients in the local best practice group (p<0.0001). They also experienced a greater improvement in quality of life. The number of adverse events in both groups was low. The test dressing provided an appropriate wound healing environment, relieved temporary and persistent wound pain, and decreased pain intensity. It was also associated with an improvement in quality of life.
La presente relazione descrive l'attivit a svolta nel 2011 dall'Istituto Nazionale di Oce... more La presente relazione descrive l'attivit a svolta nel 2011 dall'Istituto Nazionale di Oceanogra fia e di Geofisica SperimentaleOGS per conto della Regione Veneto nell'ambito della Convenzione n. 24106 - DGR n. 3801 del 09/12/2009 relativa alla gestione della Rete Sismometrica del Veneto (RSV), allo studio della sismicit a regionale ed alla ricerca sismologica a fini di protezione civile.
Annals of Geophysics, 2012
Tectonophysics, 2007
We investigate background seismic activity of the Abruzzo region, a 5000 km 2 area located within... more We investigate background seismic activity of the Abruzzo region, a 5000 km 2 area located within the Central Apennines of Italy, where in the past 600 years at least 5 large earthquakes (I = XI-X) have occurred.
Advances in Skin & Wound Care, 2014
All authors, staff, faculty, and planners, including spouses/partners (if any), in any position t... more All authors, staff, faculty, and planners, including spouses/partners (if any), in any position to control the content of this CME activity have disclosed that they have no financial relationships with, or financial interests in, any commercial companies pertaining to this educational activity.
Wound Repair and Regeneration, 2006
With an aging population venous ulceration is likely to become an increasing problem. Despite imp... more With an aging population venous ulceration is likely to become an increasing problem. Despite improvements in care and the widespread introduction of compression bandaging, the mainstay of current management, a significant proportion of venous leg ulcers remain hard to heal. Therefore, a single-blinded, randomized multicenter study was performed to compare wound size reduction using amelogenin proteins (Xelma) formulated into a solution which forms a temporary extracellular matrix on contact with the wound bed. Propylene glycol alginate 7% served as a control. Patients were randomized to receive either amelogenin protein or control treatment. The investigational products were applied weekly under soft silicone secondary dressings for up to a maximum of 12 weeks. Compression therapy was maintained throughout the investigation. Wound size reduction was measured by tracing and all wounds were photographed. In total 123 patients were recruited, 62 patients in the amelogenin group, and 61 in the control group, respectively. Subgroup analyses were performed for ulcers with a size>10 cm2 at baseline and for ulcers of duration of >12 months. The wound size reduction was greatest in the group treated with amelogenin (33.8 vs. 25.6%, n=117), this difference being greatest for larger ulcers (25 vs. 7.9% for ulcers>10 cm(2), n=61) and those of long duration (29.3 vs. 10.9% for ulcers>12-month duration, n=61). We conclude that this product may be clinically useful in the treatment of these venous leg ulcers.
Skin Pharmacology and Physiology, 2011
oriented risk assessment using concrete patient circumstances. The indication for the use of anti... more oriented risk assessment using concrete patient circumstances. The indication for the use of antiseptics results from the addition of differently weighted risk causes, for which points are assigned. Antimicrobial treatment is justified in the case of 3 or more points.
Seismological Research Letters, 2005
Journal of the American Academy of Dermatology, 2010
Journal of the American Academy of Dermatology, 2013
Livedoid vasculopathy (LV) is a noninflammatory thrombotic condition presenting in a primary idio... more Livedoid vasculopathy (LV) is a noninflammatory thrombotic condition presenting in a primary idiopathic or secondary subtype associated with abnormal coagulation factors. Different from atrophie blanche (AB), which is a clinical manifestation of certain scars, LV may have AB in combination with recurrent livedo reticularis with chronic and painful skin ulcers particularly around the ankle region, and at the back of the feet. Histology is characterized by segmental hyalinizing changes at the subintimal region of small dermal vessels with thrombotic occlusions. LV skin ulcers resolve with stellate, porcelain-white scars that need to be distinguished from similar changes seen with venous insufficiency. ''Atrophie blanche'' was originally used synonymously with ''livedoid vasculopathy.'' AB describes spontaneously occurring porcelain-white skin areas with red dots that typically occur in the context of skin changes attributed to chronic venous insufficiency. The 2 forms of ABe(1) the LV-AB complex and (2) AB in the context of chronic venous insufficiencyeare unrelated and require separate diagnostic and therapeutic approaches. Using a modified Delphi method, we have developed an international consensus document on the diagnosis and management of LV. Individual sections of this document provide advice on diagnosis and management of LV. ( J Am
Journal of Seismology, 2005
... The totally unexpected casualties became a tragedy and a shock for the Italian community. ...... more ... The totally unexpected casualties became a tragedy and a shock for the Italian community. ... A few hours after the first main event, a tempo-rary seismic network was installed in the epicentral region (Figure 2).The network was partially operat-ing on November 1st, when a ...
Journal of Diabetes and its Complications, 1999
Patients were compared with age and gendermatched healthy volunteers (Controls), who feet was inc... more Patients were compared with age and gendermatched healthy volunteers (Controls), who feet was increased and if its eventual modifications could be correlated to the severity of neuropathy, we underwent the same evaluations in the same order.
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Papers by Marco Romanelli