Andrea Maxia

Università degli Studi di Cagliari, Dipartimento di Scienze della Vita e dell'Ambiente, Faculty Member

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Andrea Maxia graduated from the University of Cagliari, Cagliari, Italy, completing a combined B.S. and M.S. degree in natural sciences, awarded with distinction, specializing in nature conservation and natural resources management. In 2015, Maxia was appointed as an Associate Professor in pharmaceutical botany at the Faculty of Biology and Pharmacy. In 2006, after completing his Ph.D. degree in pharmacology of medicinal plants at the University of Cagliari, which was funded by the same university, he joined the Faculty of Biology and Pharmacy as a Researcher in pharmaceutical botany and as a Lecturer on plant biology, plant systematics, and pharmaceutical botany. In 2001, Dr. Maxia won a scholarship at the Department of Botanical Sciences, University of Cagliari, for the MAPs project (Medicinal

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Chemical composition and biological activity of Tanacetum audibertii (Req.) DC. (Asteraceae), an endemic species of Sardinia Island, Italy

Industrial Crops and Products, Mar 1, 2015

ABSTRACT The chemical composition and antifungal activity of volatile extracts of Tanaceutum audi... more

超臨界CO_2抽出と評価その抗酸化活性,細胞毒性および細胞吸収のにより得られたLycium europaeum果実油の化学組成【Powered by NICT】

Food Chemistry, 2017

Sardinian plants with antimicrobial potential. Biological screening with multivariate data treatment of thirty-six extracts

Industrial Crops and Products, Oct 1, 2019

In this paper, thirty-six extracts from Sardinian plants were evaluated in vitro for their antimi... more In this paper, thirty-six extracts from Sardinian plants were evaluated in vitro for their antimicrobial activity towards a panel of reference strains, Staphylococcus aureus, S. epidermidis, Klebsiella pneumoniae and Escherichia coli, and for their cytotoxicity on mammalian cells. The biological data, together with total phenolic and flavonoid content of the extracts, were treated by PCA, which highlighted the positive correlation among total phenolic content and increasing antibacterial activities, and a possible involvement of flavonoids in mitigate the cytotoxicity. Thirteen extracts displayed a significant inhibitory effect towards S. aureus (IC50 from 1.4 to 153.6 µg/mL), ten out of them were active also against S. epidermidis (IC50 from 3.9 to 150 µg/mL), seven against K. pneumoniae (IC50 from 28.5 to 97.5 µg/mL), and two against E. coli (IC50 74.9 and 156.3 µg/mL). In particular, three extracts obtained from Pistacia terebinthus ssp. terebinthus, Cytinus hypocistis and Limonium morisianum emerged as promising antibacterial candidates. They exhibited remarkable inhibitory activity towards bacterial strains from clinical specimens and presenting different antibiotic-resistance profiles.

Andrea Maxia

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