Analisis Administrativo

El problema de la objetividad está en relación con la búsqueda del hombre de esa actitud que se realiza en tres campos: lo previsible, lo controlable y lo justificable. La diferencia existente entre lo previsible y lo controlable se reduce a la mayor amplitud del campo de lo previsible sobre lo controlable. Ahora bien, los tres campos hablan de la objetividad y una vez que la realidad carece de estas tres características no nos atrevemos a llamarla objetiva.

Background: Clear therapeutic guidelines for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) are missing due to the lack of randomized double-blind controlled clinical trials. Moderate yet similar clinical benefit has been demonstrated for IFN-a and high-dose ascorbic acid (AA) monotherapy in a large open clinical trial. However, there is a lack of in vivo and in vitro studies exploring and comparing the effects of high-dose AA and IFN-a treatment in the context of HAM/TSP. Therefore, we performed the first comparative analysis of the ex vivo and in vitro molecular and cellular mechanisms of action of IFN-a and high-dose AA in HAM/TSP.