Papers by ERLINA MARFIANTI dr.
Deteksi Dini dan Peningkatan Pengetahuan Penyakit Osteoporosis pada Calon Jamaah Haji Di Yogyakarta
Jurnal Abdimas Madani dan Lestari (JAMALI)/Jurnal Abdimas Madani dan Lestari, Mar 14, 2024

Proceedings of the 3rd International Conference on Cardiovascular Diseases (ICCvD 2021), Dec 18, 2022
Covid-19 pandemic has been spreading throughout the world for almost 2 years. Hypertension was on... more Covid-19 pandemic has been spreading throughout the world for almost 2 years. Hypertension was one of the most common comorbidities among Covid-19 patients. We conducted this study to investigate the correlation between hypertension and mortality in Covid-19 patients. We collected 159 medical records of Covid-19 patients at dr. Soehadi Prijonegoro Hospital, Sragen, Central Java, Indonesia between March 2020 and March 2021, which met the following inclusion criteria: diagnosed as Covid-19 from RT PCR or Antigen test of SARS-CoV-2, age more than 18 years old, inpatient hospitalization and had complete medical record data. We investigated the independent variables i.e. sex, age, length of stay in hospital, antiviral treatment, oxygen saturation and history of hypertension, increased blood pressure upon arrival, and a dependent variable i.e. mortality. We used Chi-square and logistic regression to analyze the correlation between the independent variables with mortality. Using Chi-square analysis we found that there was no significant correlation between sex (p 0.604) and history of hypertension (p 0.378) with mortality. However, there was a significant correlation between mortality and the following variables: length of stay more than 14 days, decreased oxygen saturation (<93%) upon arrival, age more than 60 years, using Favipiravir rather than Remdesivir as antiviral treatment, and increased blood pressure upon arrival (p 0.000; 0.000; 0.004; 0.021; 0.049 accordingly). Logistic regression showed that length of stay of more than 14 days, oxygen saturation of less than 93% upon arrival, age more than 60 years, and hypertension upon arrival were significantly correlated with mortality among Covid-19 patients (p 0,000; 0,000, 0,005 and 0,049 respectively). History of hypertension was not found to be correlated with mortality among Covid-19 patients. However, increased blood pressure upon arrival was significantly correlated with mortality in Covid-19 patients, along with other factors such as age more than 60 years, decreased oxygen saturation upon arrival, and length of stay more than 14 days.

Introduction: The prevalence of overweight and obesity in young adults is increasing worldwide, i... more Introduction: The prevalence of overweight and obesity in young adults is increasing worldwide, including in Indonesia. Previous studies have shown that obesity increases inflammatory factors and is closely related to the incidence of metabolic and cardiovascular diseases. Cardiometabolic risk factors such as body mass index, waist circumference, dyslipidemia, fasting blood glucose levels, and blood pressure in young adults are thought to be associated with elevated serum Hs-CRP. Objective: This study aims to determine the correlation between cardiometabolic risks and serum High-Sensitivity C Reactive Protein (Hs-CRP) levels in young adults with overweight and obesity. Methods: This research was an analytical observational study with a cross-sectional design. The research subjects were young adults (20-40 years old) with overweight and obesity in Yogyakarta who met the inclusion and exclusion criteria. Cardiometabolic risks such as blood pressure, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, blood sugar, and serum levels of Hs-CRP were examined. The correlation between cardiometabolic risks and Hs-CRP levels was analyzed through the Pearson correlation test and declared significant if p < 0.05. Results: There was a significant positive correlation between the cardiometabolic risks of body mass index (p = 0.001; r = 0.526), fasting blood glucose levels (p = 0.013; r = 0.414), waist circumference (p = 0.00; r = 0.816), total cholesterol (p = 0.10; r = 0.428), LDL cholesterol (p = 0.01; r = 0.521), as well as HDL cholesterol (p = 0.00; r =-0.747) and serum Hs-CRP levels. No significant correlation was found between age, triglyceride levels, as well as blood pressure and serum Hs-CRP levels (p > 0.05). Conclusion: There is a significant positive correlation between the cardiometabolic risks of waist circumference, body mass index, total cholesterol, HDL cholesterols, LDL cholesterols, as well as fasting blood glucose levels and serum Hs-CRP levels.

Proceedings of the 3rd International Conference on Cardiovascular Diseases (ICCvD 2021), Dec 18, 2022
The COVID-19 pandemic, which has occurred since last year, has impacted all aspects of life, incl... more The COVID-19 pandemic, which has occurred since last year, has impacted all aspects of life, including health, in particular the condition of blood pressure. Many factors affect blood pressure during this pandemic, and hypertension is caused by many conditions. The pandemic has also affected the patterns and life cycles of the society. Changes in the economy and in daily life can increase blood pressure and hypertension as they may cause psychosocial or emotional stress, changes in sleep patterns, and diurnal cycles. This study aims to investigate how anxiety levels and sleep disturbances affect blood pressure. This research is a cross-sectional study. The research method used in this research is descriptive to determine the effect of stress caused by the COVID-19 pandemic on the blood pressure of the rural residents. Statistical analysis used is descriptive analysis and linear regression test. The difference seems to be significant when p < 0.05. This research has obtained ethics approval from the Ethics Committee of the Faculty of Medicine, Islamic University of Indonesia.A total of 38 respondents participated in this study, 35 females and 3 males (ages 28-67). The results of the linear regression test showed that the level of anxiety and sleep disturbances indicated by the Hamilton Anxiety Rating Scale (HARS) score and the Pittsburgh sleep quality index (PSQI) score did not seem to statistically have a significant contribution to systolic (p 0.166) and diastolic (p 0.166) blood pressure. The results of R2 (R Square) of systolic and diastolic in this study were 0.097 and 0.027 respectively, which showed that the influence of anxiety and sleep disturbances contributed to systolic by 9.7% and diastolic 2.7%. Meanwhile, the coefficient of impact when examined separately on anxiety scores and sleep disturbance scores on systolic and diastolic blood pressures was 0.12, p 0.103; −0.016, p 0.987 and 0.98 p 0.33; −0.4 p 0.692. This may indicate that neither anxiety nor sleep disturbance scores have a significant impact on systolic and diastolic blood pressures.The findings suggest that the level of anxiety and sleep disturbances did not significantly contribute simultaneously to systolic and diastolic blood pressures.

Proceedings of the 3rd International Conference on Cardiovascular Diseases (ICCvD 2021), Dec 18, 2022
Cardiorenal syndrome (CRS) is a disorder of the heart and kidneys whereby acute or chronic dysfun... more Cardiorenal syndrome (CRS) is a disorder of the heart and kidneys whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other. Chronic abnormality in cardiac function leading to kidney injury or dysfunction was a typical characteristic of CRS type 2. Renal dysfunction frequently coexists with chronic heart disease, which in this situation, it's often difficult to establish which of the 2 diseases is the primary one. We present the case of a 74-years old male was presented with chest pain, cough, dyspnee d'effort, and diaphoresis. He had a history of chronic heart failure, atrial fibrillation, and renal insufficiency. Chest radiography revealed pulmonary edema. The electrocardiogram showed Atrial Fibrillation (AF) with Left Bundle Branch Block (LBBB). On echocardiography we found RWMA (+), ejection fraction of 24%, TAPSE 12 mm. Initial laboratory result was a high concentration of urea and diminished renal function shown as a high concentration of creatinine with eGFR was 16.1 mL/min/1.73 m2 (MDRD) and Troponin I was 630 ng/L. He was transferred to ICU with NSTEMI, heart failure, renal insufficiency, and AF with LBBB. Patient was treated with Digoxin, intravenous Furosemide, Aspirin, Clopidogrel, Candesartan, Carvedilol, Rosuvastatin, Curcuma and Aminoral. On the next day, dopamine was given due to hypotension. Three days later, there's improvement in kidney condition and urine output. Patient felt neither chest pain nor dyspnea. On the 6th day, the patient was discharged. An adequate treatment of heart failure in cardiorenal syndrome can also improve renal condition.

Proceedings of the 3rd International Conference on Cardiovascular Diseases (ICCvD 2021), Dec 18, 2022
Background The prevalence of cardiovascular disease is increasing in Indonesia. Cardiovascular di... more Background The prevalence of cardiovascular disease is increasing in Indonesia. Cardiovascular disease ranks first among the causes of mortality in the world. Controlling the risk of cardiovascular disease becomes an effort to prevent the disease incidence. Previous studies have shown that olive oil has cardioprotective potential and reduces complications of cardiovascular disease. Objective: This is a scoping review which aims to identify the effects of olive oil on reducing the risk of cardiovascular disease. Methods: This research is a scoping review with search, selection, and analysis methodology being in accordance with the standards and using appropriate keywords. The scoping review articles came from the PubMed, Google Scholar, ScienceDirect, EBSCO, Directory of Open Access Journals, and Garuda Portal databases. The studies were assessed using the eligibility criteria from the PRISMA flow diagram. The articles used were those published in national and international journals in the period of 2010-2020 and available in full text. Results: The search results in 18 research articles that fulfill the criteria. Several studies significantly show that olive oil supplementation has cardioprotective properties through reduction of the risk of cardiovascular disease incidence and prevention of cardiovascular disease complications. The risk of cardiovascular disease can be reduced by reducing inflammatory markers, improving lipid profiles, or decreasing atherosclerosis. Conclusion: Olive oil has the potential to reduce the risk of cardiovascular disease by reducing inflammatory markers, improving lipid profiles, or reducing atherosclerosis.

PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
The prevalence of non-communicable diseases (NCD) in Indonesia is currently increasing. Data from... more The prevalence of non-communicable diseases (NCD) in Indonesia is currently increasing. Data from WHO states that 71% of the causes of death worldwide are NCD. Control of risk factors and early detection of non-communicable diseases (NCD) are the keys to reducing the number of cases and mortality of NCD. Posbindu is a preventive, promotive effort that involves community participation. The ability of cadres and community awareness are not the same in every area. In this regard, our community service activities aim to optimize cadres in controlling NCD through the establishment and implementation of Posbindu. This program consists of 5 actions: Training of cadres about Posbindu, Counseling, and education to cadres and the community about non-communicable diseases, especially hypertension and diabetes mellitus, Procurement and training on the use of medical devices for Posbindu, Creation of information and communication media for health education to the public, and Establishment of Pos...
Korelasi antara Skor Depresi dengan Kadar Gula Darah dan Kadar Kolesterol Total pada Penderita Dprresi di RS Grasia Yogyakarta
FK. Universitas Islam Indonesia, 2010
Seminar Nasional Informatika Medis (SNIMed), Aug 31, 2017
Abstraksi-Secara global penyakit jantung merupakan penyakit tidak menular penyebab kematian terbe... more Abstraksi-Secara global penyakit jantung merupakan penyakit tidak menular penyebab kematian terbesar. Salah satu cara mengenali penyakit jantung adalah dengan mendiagnosis berdasarkan hasil dari elektrokardiogram (EKG) yang kemudian dianalisis oleh ahlinya. EKG merupakan gambaran dari aktivitas listrik jantung yang terdiri dari beberapa komponen. Pada penelitian ini diusulkan algoritma pembacaan waktu pada komponen EKG yang berupa durasi interval dan segmen waktu untuk mendapatkan nilainya. Nilai interval dan segmen yang didapat kemudian di proses oleh mesin inferensi Modified K-Nearest Neighbor (MKNN) untuk mendapatkan hasil diagnosis penyakit jantung. Nilai akurasi yang didapat dari menggunakan algoritma pembacaan waktu sebagai ekstraksinya dan MKNN sebagai mesin inferensinya adalah 90.22%.
Pelatihan Deteksi Dini Gangguan Kognitif dan Pembuatan Sistem Aplikasi Skrining Gangguan Kognitif Lansia Untuk Kader Kesehatan Desa
MATAPPA: Jurnal Pengabdian Kepada Masyarakat, Nov 24, 2021
Kadar resistensi pada obes dengan resistensi insulin dan tanpa resitensi insulin :: Tinjauan pustaka dan laporan penelitian

Increased systolic and diastolic blood pressure is a result of the process of blood vessel degene... more Increased systolic and diastolic blood pressure is a result of the process of blood vessel degeneration that often occurs in the elderly. A number of previous studies have shown that cystatin C is a strong predictor of cardiovascular and mortality risk in elderly individuals though the mechanism remains unclear. Cystatin C also increases in individuals with decreased renal function. The objective of this study was to determine the effects of serum cystatin C levels on the systolic and diastolic blood pressure of the elderly with normal renal function. This was an analytical observational study with a cross-sectional design. The subjects of this study were both men and women aged ≥60 years old without renal function impairment. The subjects underwent systolic and diastolic blood pressure measurements, and their venous blood was taken to check the levels of serum cystatin C. The data were analyzed using a fischer exact test. Involving 40 elderly subjects, this study found that the mea...

Perbedaan Kadar Resistin Pada Obes Dengan Resistensi Insulin Dan Obes Tanpa Resistensi Insulin
Resistin is an adipocytokine that secreted from adipose tissue, resistin level serum increased in... more Resistin is an adipocytokine that secreted from adipose tissue, resistin level serum increased in obese patients. Resistin has important biological activity on glucose and lipid metabolism, and can affect insulin resistance. Previous study suggested that high level resistin can induce insulin resistance and has contribution to impaired insulin sensitivity. The Objective of this study is to know differences of resistin level in obese with insulin resistance and obese without insulin resistance. This is a cross sectional study with obesity patients recruited from General Check Up and Endorinology outpatients clinic Sardjito General Hospital Yogyakarta. Obese patients are subjects with body mass index (BMI) ≥ 25 kg/m2. Insulin resistance was assessed using HOMA-IR (homeostasis model assessment insulin resistance), formula calculated from fasting insulin and glucose levels. Resistin was measured with ELISA technique. Differences of obese with insulin resistance and obese wit...

The number of postmenopausal women in the world in 2020 according to the World Health Organizatio... more The number of postmenopausal women in the world in 2020 according to the World Health Organization is expected to reach 1.2 billion, while in Indonesia, according to the Central Beraeu of Statistic (CBS) number of postmenopausal women in 2025 will reach 60 million people. In general, postmenopausal women will have experience a variety of complaints such as hot flush, osteoporosis, sleep disorders, obesity, anxiety, urogenital disorders, dementia and sensory impairments. Postmenopausal women will be at risk of suffering from diabetes, coronary heart disease, osteoporosis, dementia, and cancer. Various complaints and interference are due to declining ovarian hormones including estrogen and progesterone. This situation is the reason why about 1 million postmenopausal women in the UK do hormonal replacement therapy (HRT). Reports from various overseas researchs show that HRT is useful to reduce short-term symptoms of menopause, prevent osteoporosis, and decrease the incidence of colorectal cancer, but in the long run more than 4 years should be vigilance and caution considering the negative effects such as the risk of breast cancer, uterus cancer, thromboembolism, stroke, hypertension, and biliary abnormalities. Controversy over the use of HRT is increasingly becoming debate after reports of the Women Health Initiative (WHI) in 2002 which reported an increased risk of breast cancer 1.2 time. Actually, the risk is still small compared to the risk of breast cancer because of smoking. It is therefore necessary to study the use of HRT in postmenopausal women, especially in Indonesia. Based on a qualitative study of the controversial use of HRT in menopause women among clinicians in particular medical specialist in internal medicine and a specialist gynecologist and obstetrician can be seen that clinicians tend to prefer a combination of estrogen and progesterone than estrogen singles. We found the controversy of usage HRT among clinicians into three opinion consisting pesimistic opinion, natural opinion, and conditional opinion although basically only two alternative reject or accept to use the HRT. Clinicians have more concerned about the negative effects of the risk of breast cancer in postmenopausal women who use HRT. This is due to the track record of patient incomplete, incomplete examination method to monitor the negative effects of the use of HRT, HRT dose appropriate and benefit/safety of HRT remain uncertain, and inconsistent outcomes of various research reports as well as the conflict between basic science facts role of estrogen, clinical benefit and observations epidemiological studies.

Yoga merupakan salah satu aktivitas fisik yang menggunakan berbagai postur untuk mengembangkan ke... more Yoga merupakan salah satu aktivitas fisik yang menggunakan berbagai postur untuk mengembangkan kekuatan fisik, kelenturan dan ketahanan dimana dapat digunakan sebagai latihan berintensitas sedang untuk pasien dengan kapasitas latihan terbatas sehingga lebih mudah bagi orang-orang yang inaktif secara fisik. Tujuan Penelitian yaitu untuk mengetahui pengaruh yoga terhadap waist hip ratio (WHR) pada wanita di Desa Lodadi Kecamatan Ngemplak Kabupaten Sleman Yogyakarta. Penelitian ini merupakan penelitian pre–eksperimental dengan One Group Pretest - Postest Design. Subyek penelitian diperoleh dengan teknik purposive sampling di Desa Lodadi. Subyek berjumlah 30 orang. Yoga dilakukan sejak November 2018 hingga Januari 2019 setiap 2x seminggu selama 90 menit. WHR diukur dengan menggunakan meter ukur. Setelah itu data akan dianalisis dengan paired sample t-test. Hasil Penelitian menunjukkan dari 30 subyek penelitian 17 peserta termasuk dalam kriteria eksklusi. Hasil analisis statistik paired...

Karakteristik Faktor Risiko Pasien Chronic Kidney Disease (CKD) Yang Menjalani Hemodialisa DI RS X Madiun
ABSTRAK Penderita cronic kidney disease (CKD) terus meningkat setiap tahunnya, bahkan di Indonesi... more ABSTRAK Penderita cronic kidney disease (CKD) terus meningkat setiap tahunnya, bahkan di Indonesia lebih dari 200.000 kasus baru gagal ginjal stadium akhir. Faktor risiko seperti hipertensi, diabetes mellitus, penyakit kardiovaskular, glomerular, tubulointerstitial, ginjal polikistik, penggunaan obat/bahan kimia berpengaruh terhadap kejadian CKD. Penelitian ini bertujuan untuk m engetahui karakteristik faktor risiko pasien CKD yang menjalani hemodialisa. Penelitian ini merupakan penelitian non eksperimental dengan desain penelitian cross sectional. Data diperoleh melalui data sekunder periode Januari–Oktober 2016. Hasil dari penelitian ini adalah dari 88 pasien yang memenuhi kriteria inklusi, terdapat 57 pasien (64,8%) laki-laki dan 31 pasien (35,2%) perempuan, terdapat 1 pasien (1,1%) CKD pada kelompok usia 18-25 tahun, 26 pasien (29,5%) pada kelompok umur 26-45 tahun, 54 pasien (61,4%) pada kelompok umur 46-65 tahun, 7 pasien (8%) pada kelompok usia >65 tahun. Berdasarkan fakt...

Jurnal Kedokteran dan Kesehatan Indonesia, 2020
Background: Heart failure is a major health problem in the world. It is associated with high morb... more Background: Heart failure is a major health problem in the world. It is associated with high morbidity and high mortality especially in elderly patients. Most studies reported using N terminal pro-B type natriuretic peptide (NT-proBNP) in diagnosis of heart failure, but about of these tests in determining classification of severity of heart failure in the elderly remain unclear. Objective: To determine the differences NT-pro BNP levels based on the severity of diease of heart failure in elderly patients. Methods: This is an observational study with cross sectional design. Subjects were patients with diagnosed heart failure and aged = 60 years. Patients were divided into two groups, mild and severe heart failure groups according to severity of heart failure in New York Heart Association (NYHA) class. The NT Pro-BNP levels were measured for all subjects in both groups. Data was analyzed with using unpaired t test and was considered significant if p <0.05. Results: This study involv...

Cancer is one of the main causes of mortality in the world. Colorectal cancer, also known as colo... more Cancer is one of the main causes of mortality in the world. Colorectal cancer, also known as colon cancer, is a malignant tumor of the colon and rectum that begins with a polyp. Early inspection is needed to prevent and cure of colorectal cancer because in the early stages colorectal cancer showed no symptoms. At this time the development of information technology allows the quick information retrieval from an image. The aim of this research is to produce a preliminary work in the stages of information analyzing on colorectal endoscopic image extraction result in the form of polyp and bleeding by utilizing extraction technique of image information based on shape and texture. This research aimed can be the basis for the development of colorectal cancer detection system framework. The research that has been carried out gives result of characteristics that can be differentiate between colon bleeding, colon polyp, and normal colon conditions, they are aspect ratio, triangle, correlation...
Hubungan Kadar Glukosa Darah dengan Kulitas Hidup pada Pasien Diabetes Melitus Tipe II di RSUD Sleman Yogyakarta
Perbedaan Tekanan Darah Sebelum dan Sesudah Paparan Heat Stress pada Pekerja Perusahaan Industri Alumunium Yogyakarta
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Papers by ERLINA MARFIANTI dr.