Hercules R Freitas

Universidade Federal do Rio de Janeiro (UFRJ), Institute of Biophysics Carlos Chagas Filho (IBCCF), Graduate Student

UNIRIO - Universidade Federal do Estado do Rio de Janeiro, CCBS, Undergraduate

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Ph.D. graduate and M.Sc. in Biological Sciences (Biophysics), Federal University of Rio de Janeiro (UFRJ), recipient of research scholarships from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES, 2015-2016) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) --- Specialist Degree in Pharmacology (Pharm.S), Dom Bosco Catholic University (UCDB) --- Specialist Degree in Phytotherapy (Phyto.S.), AVM Integrated Faculty (AVM) --- B.Sc. in Nutrition and Registered Dietitian (R.D.), Federal University of the State of Rio de Janeiro (UNIRIO) --- Licentiate and B.Sc. in Biological Sciences, Salgado de Oliveira University (UNIVERSO) --- Author of the books Principles of Bioethics (UNIVERSO University Press) and Caminho Retrógrado (Saraiva Publishers), co-author of the book Advances in Medicine and Biology (Nova Publishers) --- Invited reviewer at Nutrition, Medicine and Biology peer-reviewed Journals --- Associate editor and reviewer for Food and Nutrition --- Lecturer experience in Biochemistry, Pharmacology, Neurophysiology, Human Anatomy and Scientific Methodology for bachelor degrees in Nutrition (UNIRIO), Dentistry, Pharmacy (UFRJ) and Physical Education (CEUCLAR) --- Currently teaching (part-time) Biological Sciences at the GayLussac Institute --- Interested in neuropharmacology, neuroglial communication, brain antioxidants, cannabinoid system and metabolism of n-3/n-6 fatty acids. (ORCID: 0000-0003-1584-9157 / ResearcherID: M-7198-2015 / Publons: a/1293925 / e-mail: [email protected]).
Supervisors: Ricardo Augusto de Melo Reis
Phone: +552139386594
Address: Rio De Janeiro, Rio de Janeiro, Brazil

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Universidade Federal do Paraná

Stefania Rossi

Sameh Fayek

Cairo University Faculty of Medicine

Mohamed Abd El Salam

Cairo University Faculty of Medicine

Musbau Akanji

University of Ilorin

ahmed fawzy

Ministry of State for Antiquities

Sameh Fayek

Cairo University Faculty of Medicine

Malak A Alyawer

Queen's University at Kingston

Hakeem Al-Anee

Ahmad J H Albaghdadi

Queen's University at Kingston

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REVIEW TRIBULUS TERRESTRIS L. (ZYGOPHYLLACEAE): SAFETY AND EFFECTIVENESS OF STEROIDAL METABOLITES

Plant extracts containing saponins and other phytosterols are regularly used as a medicinal resou... more Plant extracts containing saponins and other phytosterols are regularly used as a medicinal resource for treating several symptoms and diseases, it may be provided in simple preparations (e.g. infusions) or into highly controlled pharmaceutical formulations. Investigations have recently been focused on the role of Tribulus terrestris as an ergogenic aid for physical activity practitioners, possibly due to its androgenic potential and capacity to reduce symptoms of erectile dysfunction. We have performed a systematized review of literature according to Freitas et al. (2015) and Batista and Freitas (2016), in which a judicious search methodology were applied to exclude non-related works. Data on the use of T. terrestris are heterogeneous, and analytical studies strongly suggest the need for better standardization of active compounds in commercial supplements, however, clinical trials and experimental data indicate that its effects occur in a dose-dependent manner, acting weakly on the production of androgen/estrogen hormones, but stimulating pathways related to libido and sexual behavior, especially in female subjects. T. terrestris extracts have failed to promote significant improvements in physical activity performance.

Hercules R Freitas

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