Pharmacy

Darah merupakan sampel yang paling baik untuk identifikasi senyawa obat atau zat aktif lainnya baik untuk tujuan kualitatif ataupun kuantitatif. Sampel darah harus diambil oleh petugas yang terampil untuk memastikan kebenaran sampel tersebut. Plasma darah adalah cairan berwarna kuning yang dalam reaksi bersifat sedikit alkali. Komposisi dari plasma darah adalah air, protein (albumin, globulin, fibrinogen dan protrombin), ionion (Na, K, Ca, Mg, Cl,

Kompartemen dua IV Pada model kompartemen-dua dianggap bahwa obat terdistribusi ke dalam dua kompartemen. Kompartemen kesatu dikenal sebagai kompartemen sentral, yaitu: darah, cairan ekstra-selular, dan jaringan-jaringan dengan perfusi tinggi, kompartemen-kompartemen ini secara cepat terdifusi oleh obat. Kompartemen kedua merupakan kompartemen jaringan, yang

NSAID menjadi salah satu pilihan terapi untuk menghilangkan rasa nyeri.Namun, penggunaanya dalam jangka panjang dapat memicu efek samping yaitu pendarahan gastrointestinal. Oleh karena itu, diperlukan analgesik alternatif yang memiliki efek terapi yag sama dan efek samping yang lebih rendah. Salah satu tanaman yang memiliki potensi sebagai analgesik alternatif adalah Jeruk Limau (Citrus amblycarpa) yang dimanfaatkan sebagai obat kesemutan dan kram secara empiris. Penelitian ini dilakukan dengan tujuan untuk mengetahui aktivitas analgesik pada ekstrak etanol daun Citrus amblycarpa sebagai analgesik pada mencit putih jantan galur balb/c. Salah satu metode yang digunakan dalam pengujian aktivitas analgesik adalah metode Hot Plate. Penelitian dilakukan dengan membagi 30 ekor mencit ke dalam 6 kelompok kemudian masing-masing kelompok diberikan suspensi uji yang terdiri dari CMC-Na 1% sebagai kontrol negatif, suspensi natrium diklofenak dosis 6,5 mg/kgBB sebagai kontrol positif, dan suspe...

The purposes of this study were to evaluate the influences of oleic acid, propylene glycol and iontophoretic on the transport of propranolol HCl and to know optimum formula. Eight conditions were prepared according to 2 3 factorial design emplyoing oleic acid, propylene glycol, and iontophoretic. Enhancement effect on transport of propranolol HCl was investigated across hairless rat skin. The study was carried out by using vertical diffusion cell.

Agung Dewantara. (S601002001). 2016. Pengaruh Pemberian Zink Selama 5 Hari Terhadap Kadar Tumor Necrosis Factor-α dan Perbaikan Klinis Penderita Pneumonia. Tesis. Supervisor I: Dr. Reviono, dr., Sp.P(K). II: Prof. Dr. Suradi, dr., Sp.P(K),MARS. Program Pendidikan Dokter Spesialis Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret Surakarta. ABSTRAK PENGARUH PEMBERIAN ZINK SELAMA 5 HARI TERHADAP TUMOR NECROSIS FACTOR-α DAN PERBAIKAN KLINIS PENDERITA PNEUMONIA ABSTRAK Agung Dewantara Latar Belakang: Penegakan prognosis pneumonia menggunakan biomarker antara lain d Tumor Necrosis Factor-α (TNF-α). Tujuan utama tatalaksana pneumonia adalah untuk mencapai perbaikan klinis terutama dengan pemberian antibiotik. Pemberian terapi tambahan antara lain suplementasi zink diusulkan pada beberapa penelitian untuk memperbaiki outcome. Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh pemberian zink selama 5 hari terhadap kadar endothelin-1 dan per...

Extract of mangosteen rind (Garcinia mangostana L.), have been studied have anti-burn activity. Designing a cold cream formulation containing the extract was expected to facilitate the application. This study was aimed to determine the pharmaceutical physical properties of cold cream. Cold cream preparation was performed at 60 °C then it tested on 0 to day 28 after preparation to determine the pharmaceutical physical properties of the cold cream. The physical evaluation includes homogeneity test, the droplet size distribution, type of cream, rheological, and the degree of phase separation, descriptively. The results showed good physical properties, homogeneous cream, with a droplet size of <10μm, cream-type W/O, with a thixotropic rheological and degrees separation of 1. Keyword : cold cream, physical properties, mangosteen rind extract 134 Media Farmasi, Vol. 11 No.2 September 2014 :133-142

Pada edisi ini, Jurnal Media Farmasi menyajikan artikel yang semuanya merupakan hasil penelitian. Sembilan artikel dari luar Fakultas Farmasi UAD membahas, (1) Studi pengguna spektrofometri inframerah dan kemometrika (2) Optimasi formula matrik patch mukoadhesif ekstrak daun sirih (Piper batle L.) (3) Pengembangan basic cold cream ekstrak kulit manggis (Garcinia mangostana L.) (4) Aktivitas antioksidan ekstrak etanolik berbagai jenis sayuran (5) Layanan pesan singkat pengingat (6) Pola peresepan antiemetik pada penderita dispepsia pasien dewasa dan lanzia (7) Evaluasi kepatuhan pasien diabetes melitus tipe 2 (8) Pengaruh pengetahuan dan sikap orang tua terhadap swamedikasi obat demam pada anak. Tiga artikel dari penelitian Fakultas Farmasi UAD yang membahas tentang : (1) Penggunaan antibotik pada pasien leukemia akut dewasa (2) Formula granul kombinasi ekstrak terpurifikasi herba pegagan (Centella asiatica (L) Urban) dan herba sambiloto (Andrographis paniculata) (Burm.f.)Ness) (3) efek ekstrak etanol kelopak rosela (Hibiscus sabdariffa L). Harapan kami, jurnal ini dapat bermanfaat bagi pembaca atau menjadi referensi peneliti lain. Kritik dan saran membangun, senantiasa kami terima dengan tangan terbuka. Dewan editor Kata kunci : ekstrak daun sirih, mentol, PEG 400, mukoadhesif matrik patch

Dendeng is a culinary icon of Indonesia. Therefore, D’Cuby is tried to start being a business that is engaged in the culinary field with the concept of processing green plants into healthy and nutritious snacks at West Sumatra in the digital era. When we hear the word jerky, the first thing that we remember is one of the foods originated from Padang which is made from crispy and savory beef. In this product, the beef jerky that will be made coming from the basic ingredients of cassava leaves. Cassava leaf jerky is formulated and processed using special spices, besides being highly nutritious, this cassava leaf jerky does not contain cholesterol. This is because cassava leaves do not contain meat elements. Compared to normal beef jerky, D’Cuby will eliminate the use of ordinary transparent plastic which is not practical. This product is packaged in 4 flavor variants, namely Original Taste, Balado, BBQ, and Grilled Corn with a price of IDR 10,000 each.  Ingredients that we need in mak...

Tomato (Solanum Lycopersicum) is a horticultural product that has the potential, health and has promising market prospects. Tomato contain a carotenoid compound called lycopene. tomato red. This carotenoid compound is well known as a compound that has high antioxidant power, this compound is able to fight free radicals caused by pollution and UV radiation. Alpha lipoic acid (ALA) is an antioxidant compound that is able to bind free radicals and regenerate antioxidants vitamin C, vitamin E. , and coenzyme Q 10

Obesity is a condition in which fat is abnormally accumulated in fat tissue due to unhealthy lifestyles such as high carbohydrates and high fats diets. Lemon (Citrus limon) is one of the nutritious medicinal plants that have not been widely known to the public that is used as an obesity drug. The purpose of this research is to fi nd the chemical compound in lemon plants that potentially has an antiobesity activity at ascorbic acid. The method that been used in this research is in-silico analysis trough molecular docking of chemical compound that potentially has an antiobesity activity in Lemon plants.The software that been used in this research is Pyrx, Avogadro, Discovery Studio, PyMol, Chem3D, and ChemDraw. The results of this study are the ability of the active compound Ascorbic Acid (The most influential Glycogen Synthase Kinase 3 beta compound) to bind CuO ligands.

Background: The process of procurement of supplies is a very important in manufacturing company, without supplies, the company will face a difficult continuity of the production process. Aim: This research is to compare the amount of raw material purchase, frequency of purchase of raw materials, the frequency of delivery of raw materials, and the total cost of procurement of raw material inventories carried out using traditional methods and modeling methods EOQ in Cosmetics Company. Method: Data were collected using the data of the company in 2014-2015 and interviews with the owners and employees of the Company Cosmetics. Results: From this research is obtained the comparison of traditional methods and modeling EOQ ie the amount of raw material purchases in one message 1000kg: 8.440kg increased by 8.44 times, frequency of purchase of raw materials 24: 6 times, frequency of delivery of raw materials 24: 6 times. Conslusions: Total savings cost of raw material inventory control 70% of...