Papers by Lourdes Cardoso
The Journal of Supercritical Fluids, 2017
Mango leaf extract (MLE) was impregnated into polyester by supercritical process Pressure and... more Mango leaf extract (MLE) was impregnated into polyester by supercritical process Pressure and temperature affected the loading capacity of polyphenols into polyester A rapid depressurization step significantly increased the polyphenols loading The MLE conserved its antioxidant activity after the impregnation process The impregnated samples with MLE presented good antibacterial activity
Polymers, 2021
A supercritical solvent impregnation (SSI) technique was employed to incorporate, by batch- and s... more A supercritical solvent impregnation (SSI) technique was employed to incorporate, by batch- and semicontinuous-modes, bioactive olive leaf extract (OLE) into a food-grade multilayer polyethylene terephthalate/polypropylene (PET/PP) film for active food packaging applications. The inclusion of OLE in the polymer surfaces significantly modified the colour properties of the film. A correlation of 87.06% between the CIELAB colour parameters and the amount of the OLE impregnated in the film was obtained which suggests that colour determination can be used as a rapid, non-destructive technique to estimate the OLE loading in the impregnated matrices. The UV barrier and water permeability properties of the films were not significantly modified by the incorporation of OLE. The migration of OLE into a 50% (v/v) ethanol food simulant demonstrated faster release of OLE from the PP surface than from the PET surface which may be due to the different interactions between OLE and each polymer.
Agronomy
Supercritical fluid extraction (SFE), using CO2, is a novel, sustainable and very efficient techn... more Supercritical fluid extraction (SFE), using CO2, is a novel, sustainable and very efficient technique for the recovery of highly apolar compounds. However, the recovery of phenolic compounds requires the use of different co-solvent combinations such as water and ethanol to enhance the recovery of these compounds through the optimization of a number of variables. In this sense, the effect of pressure (100, 150 and 200 bar), temperature (50, 65 and 80 °C), extraction time (30, 60, 90, 120, 150 and 180 min) and the effect of the different percentages of ethanol and water as co-solvents on the composition and phenolic content of moringa leaf extracts were evaluated. Six major flavonoids were identified by ultra-high-performance liquid chromatography coupled to a quadrupole-time-of-flight mass spectrometer (UHPLC-Q-ToF-MS). Pressure and temperature had a significant effect on the phenolic composition of the extracts, as well as on their concentrations. The highest concentration of total ...
Antioxidants
The leaves of Olea europaea as agricultural waste represent a convenient source of antioxidants. ... more The leaves of Olea europaea as agricultural waste represent a convenient source of antioxidants. In combination with supercritical CO2 (scCO2), assisted impregnation is an interesting strategy for the preparation of biomedical devices with specific bioactivity. For this purpose, 3D-printable filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) were employed for the supercritical impregnation of ethanolic olive leaves extract (OLE) for biomedical application. The extraction of OLE was performed using pressurized liquids. The effect of pressure (100–400 bar), temperature (35–55 °C), and the polymer type on the OLE impregnation and the swelling degree were studied including a morphological analysis and the measurement of the final antioxidant activity. All the studied variables as well as their interactions showed significant effects on the OLE loading. Higher temperatures favored the OLE loading while the pressure presented opposite effects at values higher than 250...
Review & Expositor, 1990
The materials in this book were first presented through the Intercollegiate Seminar series of the... more The materials in this book were first presented through the Intercollegiate Seminar series of the Department of Anthropology at the School of Oriental and African Studies (University of London). Six of the nine essays in this volume originated in that forum. Three others were secured for balance, and balance there is. Each article examines the nature of religious fundamentalism as evidenced in numerous contemporary religious traditions. These include Islam, Judaism, Sikhism, Wahabism, Hinduism, and various forms of Protestantism in the U.S., India, Africa, Turkey, and Iran. The writers are from the fields of sociology, history, anthropology, theology, and social studies. Each article provides extensive definitions and analysis of fundamentalism in particular religions and regions. In addition, the entire volume illustrates the way in which fundamentalist movements have appeared throughout the world, largely in reaction to modernism and modernity. (Defining all those terms is a major task.) The three chapters on Protestant fundamentalism offer insightful overviews of specific movements. Steve Bruce's essay on the Moral Majority is helpful, but now a bit dated, due to recent developments. Studies of non-Christian fundamentalism are fascinating and provide information which is often overlooked by students of Christianity. The book is a fine 652 resource for continuing study of the worldwide import of fundamentalism.
A high-pressure equipment supplied by Thar Technology (Pittsburgh, PA, USA, model SF100) was used... more A high-pressure equipment supplied by Thar Technology (Pittsburgh, PA, USA, model SF100) was used to carried out the supercritical impregnation of alginate dressings with mango leaf extract. The extract was introduced into the 100 mL-vessel by the cosolvent pump and two dressing samples were placed in the impregnation cell into a stainless support. The vessel was closed and then the CO 2 was pumped until reach the conditions of pressure (P) and temperature (T). System was maintained for 2 h in static method. A washing step was included, and finally the system was depressurized. P and T were studied in a range of 200-400 bar and 35-55 °C.
Food & Function, 2020
The wastes generated by cherimoya cultivation and processing industries should be contemplated as... more The wastes generated by cherimoya cultivation and processing industries should be contemplated as a valuable source of bioactive alkaloids, with potential in pharmaceutical applications for the treatment or prevention of chronic diseases.
Antioxidants
Some citrus by-products such as orange peel contains valuable compounds that could be recovered a... more Some citrus by-products such as orange peel contains valuable compounds that could be recovered and restored into the food chain. In this study, an efficient valorization of orange peel has been investigated using green extraction, fractionation, and impregnation techniques. The first step included its extraction using CO2 and ethanol under different pressure (200–400 bar) and temperature (35–55 °C) conditions. The extracts obtained at 300 bar and 45 °C showed strong antioxidant with moderate antimicrobial activity. Then, the extract was subjected to a sequential fractionation process. The fraction obtained at 300 bar, 45 °C, and using 32% ethanol showed the strongest antioxidant and antimicrobial activity with a high extraction yield. Finally, the potential of the two best extracts (obtained at 400 bar and 45 °C before any fractionation and the fractions obtained at 300 bar, 45 °C using 32% ethanol) was determined by conducting an impregnation process to obtain an antioxidant food-...
High-Pressure Fractionation of Tropical Fruits with Potential Antibacterial Activity: M. Indica L... more High-Pressure Fractionation of Tropical Fruits with Potential Antibacterial Activity: M. Indica L. and B. Guineensis María Teresa Fernández-Ponce.; Zamira E. Soto Varela, Pacífico Castro Gil; Lourdes Casas; Casimiro Mantell; Enrique J. Martínez de la Ossa Department of Chemical Engineering and Food Technology, Faculty of Science, University of Cadiz, International Agri-food Campus of Excellence, ceiA3, Box 40, 11510 Puerto Real, Cadiz (Spain) Faculty of Basic and Biomedical Sciences, Simon Bolivar University, Barranquilla (Colombia) [email protected]
Polymers, 2021
Ketoprofen (KET) is an anti-inflammatory drug often used in medicine due to its analgesic
and ant... more Ketoprofen (KET) is an anti-inflammatory drug often used in medicine due to its analgesic
and antipyretic effects. If it is administered in a controlled form by means of different dosing devices, it acts throughout the patient’s recovery period improving its efficacy. This study intends to support the use of supercritical solvent impregnation (SSI) as an efficient technique to develop polylactic acid (PLA) functionalized with ketoprofen, for use as controlled drug release devices. For this purpose, firstly, the influence of different SSI variables on the desirable swelling of the polymer structure, while
avoiding their foaming, were evaluated. Then, the resulting ketoprofen loading was evaluated under different pressure/temperature conditions. It was generally found that as pressure and temperature are higher, the drug impregnation loads also increase. The maximum impregnation loads (at about
9% KET/PLA) were obtained at 200 bar and 75 ◦C. In vitro drug release tests of the impregnated compound were also carried out, and it was found that drug release profiles were also dependent on the specific pressure and temperature conditions used for the impregnation of each polymer filament
The Journal of Supercritical Fluids, 2021
The aim of the study was to establish a green protocol for pectin extraction from unripe papaya f... more The aim of the study was to establish a green protocol for pectin extraction from unripe papaya flour (UPF), comparing conventional acid hydrolysis (CONV) and compressed fluid extraction techniques, including Pressurized Hot Water Extraction (PHWE) and Enhanced Solvent Extraction (ESE). Highest pectin yields were achieved with ESE (216 ± 10.8 mg g −1) when CO 2 +H 2 O (20:80) + citric acid (0.05 mol L −1) was applied (40 MPa/80°C/ 60 min/300-710 µm), similar to that obtained by CONV (202 ± 49.5 mg g −1) and PHWE (208.0 ± 9.4 mg g −1) using oxalic acid. UPF pectin presented an average galacturonic acid (GalA) content of 73% (w/w) and degree of esterification (DE) of 57.8%, and it was composed predominantly of galactose, glucose and rhamnose. This pectic substance has been shown to contain two main types of pectic chains: rhamnogalacturonan-I (RG-I, average 58%) proportionally higher than homogalacturonan (HG, average 28%). Compressed fluid extraction techniques allowed obtaining high quality pectin with similar composition to other commercial products.
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Papers by Lourdes Cardoso
and antipyretic effects. If it is administered in a controlled form by means of different dosing devices, it acts throughout the patient’s recovery period improving its efficacy. This study intends to support the use of supercritical solvent impregnation (SSI) as an efficient technique to develop polylactic acid (PLA) functionalized with ketoprofen, for use as controlled drug release devices. For this purpose, firstly, the influence of different SSI variables on the desirable swelling of the polymer structure, while
avoiding their foaming, were evaluated. Then, the resulting ketoprofen loading was evaluated under different pressure/temperature conditions. It was generally found that as pressure and temperature are higher, the drug impregnation loads also increase. The maximum impregnation loads (at about
9% KET/PLA) were obtained at 200 bar and 75 ◦C. In vitro drug release tests of the impregnated compound were also carried out, and it was found that drug release profiles were also dependent on the specific pressure and temperature conditions used for the impregnation of each polymer filament
and antipyretic effects. If it is administered in a controlled form by means of different dosing devices, it acts throughout the patient’s recovery period improving its efficacy. This study intends to support the use of supercritical solvent impregnation (SSI) as an efficient technique to develop polylactic acid (PLA) functionalized with ketoprofen, for use as controlled drug release devices. For this purpose, firstly, the influence of different SSI variables on the desirable swelling of the polymer structure, while
avoiding their foaming, were evaluated. Then, the resulting ketoprofen loading was evaluated under different pressure/temperature conditions. It was generally found that as pressure and temperature are higher, the drug impregnation loads also increase. The maximum impregnation loads (at about
9% KET/PLA) were obtained at 200 bar and 75 ◦C. In vitro drug release tests of the impregnated compound were also carried out, and it was found that drug release profiles were also dependent on the specific pressure and temperature conditions used for the impregnation of each polymer filament