Sumedha Nitin Prabhu
Dr. Sumedha N. Prabhu earned a B.Sc. in biotechnology from the University of Mumbai, India, in 2011, and a master's degree in biotechnology from the same university in 2013. She has pursued a PhD degree in Biomedical Engineering from the School of Engineering, Macquarie University, Sydney, Australia. Her thesis is entitled "Development of a Point-of-Care Diagnostic Prototype System for Kidney Health Monitoring". Her research interest includes smart sensing systems, the internet of things, and embedded systems for the early detection of various diseases in humans. Currently, Sumedha is working as a Postdoctoral Research Fellow at the University of Cincinnati, Cincinnati, USA under Assoc. Prof. Tao Li.
Sumedha has worked as a Senior Research Assistant in the School of Health Sciences at The University of Newcastle, Australia under Laureate Prof. Clare Collins.
Sumedha was awarded AUD 5000.00, a highly competitive Macquarie University Postgraduate Research Fund (PGRF) grant during her early third year of PhD. Sumedha has received two People's Choice Awards during her PhD candidature.
Recently Sumedha won a Silver Award from the Early Career Women in STEM Paper & Grant Writing Association. The competition was jointly organized by the University of Technology Sydney, Australian National University, The University of Sydney, Material Australia, Electron Devices Society, ARC Centre of Excellence in Exciton Science, Australian Institute of Physics, MDPI crystals journal, ARC Centre of Excellence for Enabling Eco-Efficient Beneficiation of Minerals and ARC Centre of Excellence for Transformative Meta-Optical Systems.
Sumedha has also participated in 3 Minute Thesis (3MT), an Asia Pacific level competition which was initiated by The University of Queensland, and she won a total of 3 prizes at Macquarie University level. In the 3MT competition, she initially won third prize at the School of Engineering level. On further levels, she also won two People’s Choice Awards, first at the Faculty of Science and Engineering and second at the entire Macquarie University level. During this time, she was honoured twice with cash prizes and once with a small research grant. After her 3MT People’s Choice win on the entire university level, the Macquarie University celebrated Sumedha's win with her official photoshoot. They also invited SBS world news presenter for Australia, Mr Anton Enus, to train Sumedha for an even better presentation style. Macquarie University had also audio-visually recorded her 3MT speech in their on-campus video recording studio. Her audio-visually recorded 3MT speech in the MQ video recording studio was posted by Macquarie University on their official YouTube channel (https://www.youtube.com/watch?v=pdXO71T9bTQ&feature=youtu.be). Sumedha's 3MT success was posted by the School of Engineering Department in their monthly newsletter. Her 3MT compete success was covered by journalist Rhea Nath from an Indo-Australian Media channel called IndianLink media over the telephonic interview and published Sumedha's success on their official media website (https://www.indianlink.com.au/features/5-minute-home-kidney-health-test-wins-three-uni-awards/), Twitter handle, LinkedIn as well as a Facebook page. Sumedha has also received an offer to commercialise my Point-of-Care diagnostic device prototype system on a larger scale from TiE Sydney (an entrepreneur supportive non-profit organization from the greater Sydney area).
Community engagement:
Sumedha is an active member of the professional technical society like IEEE. IEEE Macquarie University Student Branch Women in Engineering has also recognized her research work and success. They invited her as a guest speaker in their Women in Engineering workshop where she delivered a talk over a topic entitled “Girl’s Voice”.
Research interests:
Sumedha's PhD research focuses on kidney healthcare from home. She has also developed a prototype model that allows the connection of a functionalised sensor and selective measurement of creatinine levels from samples. This device transmits creatinine level data to the internet and can be used in the future by physicians to track the health records of their patients from distance (Point-of-Care). In the future, with further development on her prototype system, a patient can measure their creatinine concentration by testing a single blood drop at home. Therefore, Sumedha's developed prototype model has a huge scope as a diagnostic tool in modern pathological research. The main important parameters of her work can be listed as functionality, specificity, repeatability, reusability, accuracy, low-cost, low-power, long-distance, and portability. Sumedha has currently developed a Point-of-Care diagnostic device prototype system for the detection of creatinine from the human serum samples.
Supervisors: Prof. Subhas Mukhopadhyay, A./Prof. Guozhen Liu, A./Prof. Andrew Davidson, and A./Prof. Mohsen Asadnia
Phone: 5133149181
Sumedha has worked as a Senior Research Assistant in the School of Health Sciences at The University of Newcastle, Australia under Laureate Prof. Clare Collins.
Sumedha was awarded AUD 5000.00, a highly competitive Macquarie University Postgraduate Research Fund (PGRF) grant during her early third year of PhD. Sumedha has received two People's Choice Awards during her PhD candidature.
Recently Sumedha won a Silver Award from the Early Career Women in STEM Paper & Grant Writing Association. The competition was jointly organized by the University of Technology Sydney, Australian National University, The University of Sydney, Material Australia, Electron Devices Society, ARC Centre of Excellence in Exciton Science, Australian Institute of Physics, MDPI crystals journal, ARC Centre of Excellence for Enabling Eco-Efficient Beneficiation of Minerals and ARC Centre of Excellence for Transformative Meta-Optical Systems.
Sumedha has also participated in 3 Minute Thesis (3MT), an Asia Pacific level competition which was initiated by The University of Queensland, and she won a total of 3 prizes at Macquarie University level. In the 3MT competition, she initially won third prize at the School of Engineering level. On further levels, she also won two People’s Choice Awards, first at the Faculty of Science and Engineering and second at the entire Macquarie University level. During this time, she was honoured twice with cash prizes and once with a small research grant. After her 3MT People’s Choice win on the entire university level, the Macquarie University celebrated Sumedha's win with her official photoshoot. They also invited SBS world news presenter for Australia, Mr Anton Enus, to train Sumedha for an even better presentation style. Macquarie University had also audio-visually recorded her 3MT speech in their on-campus video recording studio. Her audio-visually recorded 3MT speech in the MQ video recording studio was posted by Macquarie University on their official YouTube channel (https://www.youtube.com/watch?v=pdXO71T9bTQ&feature=youtu.be). Sumedha's 3MT success was posted by the School of Engineering Department in their monthly newsletter. Her 3MT compete success was covered by journalist Rhea Nath from an Indo-Australian Media channel called IndianLink media over the telephonic interview and published Sumedha's success on their official media website (https://www.indianlink.com.au/features/5-minute-home-kidney-health-test-wins-three-uni-awards/), Twitter handle, LinkedIn as well as a Facebook page. Sumedha has also received an offer to commercialise my Point-of-Care diagnostic device prototype system on a larger scale from TiE Sydney (an entrepreneur supportive non-profit organization from the greater Sydney area).
Community engagement:
Sumedha is an active member of the professional technical society like IEEE. IEEE Macquarie University Student Branch Women in Engineering has also recognized her research work and success. They invited her as a guest speaker in their Women in Engineering workshop where she delivered a talk over a topic entitled “Girl’s Voice”.
Research interests:
Sumedha's PhD research focuses on kidney healthcare from home. She has also developed a prototype model that allows the connection of a functionalised sensor and selective measurement of creatinine levels from samples. This device transmits creatinine level data to the internet and can be used in the future by physicians to track the health records of their patients from distance (Point-of-Care). In the future, with further development on her prototype system, a patient can measure their creatinine concentration by testing a single blood drop at home. Therefore, Sumedha's developed prototype model has a huge scope as a diagnostic tool in modern pathological research. The main important parameters of her work can be listed as functionality, specificity, repeatability, reusability, accuracy, low-cost, low-power, long-distance, and portability. Sumedha has currently developed a Point-of-Care diagnostic device prototype system for the detection of creatinine from the human serum samples.
Supervisors: Prof. Subhas Mukhopadhyay, A./Prof. Guozhen Liu, A./Prof. Andrew Davidson, and A./Prof. Mohsen Asadnia
Phone: 5133149181
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Conference Presentations by Sumedha Nitin Prabhu
Impedance Spectroscopy (EIS) Point-of-Care (PoC) diagnostic
device to detect the creatinine concentration from the serum is
presented. A Micro-Electro-Mechanical Systems (MEMS)
sensor was used for measuring the electrochemical properties
of Sample Under Test (SUT). The EIS technique was utilised
along with the sensor to find out different creatinine
concentrations in heat-inactivated serum samples. Creatinine
specific Molecularly Imprinted Polymerization (MIP)-coated
sensor was used to measure the levels of creatinine followed by
the development of a LoRaWAN-based PoC diagnostic device.
In the next step, the results obtained from the diagnostic device
were cross-verified by using standard Creatinine Colorimetric
Assay Kit. The results were found to be promising to further
continue the research.
constantly get diffused in the blood and filtered by the kidneys to
minimize levels of waste content related to blood toxicity for
maintaining a healthy balance in the living body. In the current
research, we have developed a sensing polymer system for the
detection of side effects of cancer chemotherapy on human kidneys
for determining the creatinine levels. The proposed research is
related to the real-time detection of levels creatinine in an aqueous
medium. The polymer was surface characterized using Field
Emission Scanning Electron Microscope (FESEM) and Energy
dispersive analysis X-ray (EDAX) and found to be structurally
isotropic as well as monodispersed and chemically pure in nature.
Fourier-transform infrared spectroscopy (FTIR) confirmed the
successful removal of creatinine from the MIP polymer by breaking
Amide bonding. The sensing polymer system is able to determine
concentrations within the range of 1 – 50 parts per million (ppm)
when checked using ultra-high-performance liquid chromatography
(UHPLC). The results highlight the future possibility of modifying
this system for early levels of creatinine rise for preventing lifethreatening
conditions and providing indications to medical
practitioners in the form of ppm unit results where they can alter the
chemotherapy medications or reduce the total drug dosage to avoid
health disorders such as Acute Kidney Damage and Acute Kidney
Failure.
Papers by Sumedha Nitin Prabhu
Impedance Spectroscopy (EIS) Point-of-Care (PoC) diagnostic
device to detect the creatinine concentration from the serum is
presented. A Micro-Electro-Mechanical Systems (MEMS)
sensor was used for measuring the electrochemical properties
of Sample Under Test (SUT). The EIS technique was utilised
along with the sensor to find out different creatinine
concentrations in heat-inactivated serum samples. Creatinine
specific Molecularly Imprinted Polymerization (MIP)-coated
sensor was used to measure the levels of creatinine followed by
the development of a LoRaWAN-based PoC diagnostic device.
In the next step, the results obtained from the diagnostic device
were cross-verified by using standard Creatinine Colorimetric
Assay Kit. The results were found to be promising to further
continue the research.
constantly get diffused in the blood and filtered by the kidneys to
minimize levels of waste content related to blood toxicity for
maintaining a healthy balance in the living body. In the current
research, we have developed a sensing polymer system for the
detection of side effects of cancer chemotherapy on human kidneys
for determining the creatinine levels. The proposed research is
related to the real-time detection of levels creatinine in an aqueous
medium. The polymer was surface characterized using Field
Emission Scanning Electron Microscope (FESEM) and Energy
dispersive analysis X-ray (EDAX) and found to be structurally
isotropic as well as monodispersed and chemically pure in nature.
Fourier-transform infrared spectroscopy (FTIR) confirmed the
successful removal of creatinine from the MIP polymer by breaking
Amide bonding. The sensing polymer system is able to determine
concentrations within the range of 1 – 50 parts per million (ppm)
when checked using ultra-high-performance liquid chromatography
(UHPLC). The results highlight the future possibility of modifying
this system for early levels of creatinine rise for preventing lifethreatening
conditions and providing indications to medical
practitioners in the form of ppm unit results where they can alter the
chemotherapy medications or reduce the total drug dosage to avoid
health disorders such as Acute Kidney Damage and Acute Kidney
Failure.
(IoT)-based smart homes are booming in the market where a large number of IoTconnected daily used items are commercially available. These devices are used in
the smart homes for ubiquitous monitoring of the different activities of the residing
people. This chapter gives an overview of some of the smart devices available for
IoT-based smart homes along with some of the research work done on IoT-based
smart homes in the laboratory. This also showcases some of the sensors that have
been used for biomedical applications and have the potential to be used in
smart homes.