olif by Chirag Berry

World Neurosurgery, 2019
Background: Oblique lumbar interbody fusion (OLIF) takes advantage of the wide interval between t... more Background: Oblique lumbar interbody fusion (OLIF) takes advantage of the wide interval between the
aorta and the left-sided psoas muscle to access the lumbar spine allowing a minimally invasive approach
for interbody fusion with lower associated morbidity. As this approach is gaining popularity among spine
surgeons, it is important to understand the potential pitfalls that may arise in patients with congenital
anomalies of the vascular anatomy.
Case description: We present a case of a persistent left-sided inferior vena cava (IVC) affecting the side
of approach in a patient undergoing lumbar interbody fusion through an oblique pre-psoas
retroperitoneal approach. Preoperative imaging of our patient revealed a persistent left-sided inferior
vena cava with a wide interval between the aorta and the right-sided psoas allowing us a right-sided
oblique approach.
Conclusions: Thorough preoperative imaging evaluation is essential to identify vascular anomalies that
may hinder oblique pre-psoas retroperitoneal approach to the lumbar spine. Although rare, double IVC
or isolated Left IVC may complicate the oblique approach.

The Spine Journal, 2020
Background context: The oblique prepsoas retroperitoneal approach to the lumbar spine for interbo... more Background context: The oblique prepsoas retroperitoneal approach to the lumbar spine for interbody fusion or oblique lumbar interbody fusion (OLIF) provides safe access to nearly all lumbar levels. A wide interval between the psoas and aorta allows for a safe and straightforward left-sided oblique approach to the discs above L5. Inclusion of L5-S1 in this approach, however, requires modifications in the technique to navigate the complex and variable vascular anatomy distal to the bifurcation of the great vessels. While different oblique approaches to L5-S1 have been described in the literature, to our knowledge, no previous study has provided guidance for the choice of technique.
Purpose: Our objectives were to evaluate our early experience with the safety of including L5-S1 in OLIF using 3 different approach techniques, as well as to compare early complications between OLIF with and without L5-S1 inclusion.
Study design: Retrospective cohort study.
Patient sample: Of the 87 patients who underwent lumbar interbody fusion at 167 spinal levels via an OLIF approach, 19 included L5-S1 (group A) and 68 did not (group B).
Outcome measures: Demographics, levels fused, indications, operative time (ORT), estimated blood loss (EBL), vascular ligation, intraoperative blood transfusion, length of stay (LOS), discharge to rehabilitation facility, and complications (intraoperative, early ≤90 days, and delayed >90 days) were retrospectively assessed and compared between the groups.
Methods: A retrospective chart and imaging review of all consecutive patients who underwent OLIF at a single institution was performed. Indications for OLIF included symptomatic lumbar degenerative stenosis, deformity, and spondylolisthesis. The L5-S1 level, when included, was approached via one of the following 3 techniques: (1) a left-sided intrabifurcation approach; (2) left-sided prepsoas approach; and (3) right-sided prepsoas approach. Vascular anatomic variations at the lumbosacral junction were evaluated using the preoperative magnetic resonance imaging (MRI), and a "facet line" was proposed to assess this relationship. A minimum of 6 months of follow-up data were assessed for approach-related morbidities.
Results: Demographics and operative indications were similar between the groups. The mean follow-up was 10.8 (6-36) months. ORT was significantly longer in group A than in group B (322 vs. 256.3 min, respectively; p=.001); however, no difference in ORT between the two groups was found in the subanalyses for 2- and 3-level surgeries. Differences in EBL (260 vs. 207.91 cc, p=.251) and LOS (2.76 vs. 2.48 days, p=.491) did not reach statistical significance. Ligation of the iliolumbar vein, segmental veins, median sacral vessels, or any vascular structure, as needed for adequate exposure, was required in 13 (68.4%) patients from group A and 4 (5.9%) from group B (p<.00001). Two patients suffered minor vascular injuries (1 in each group); however, no major vascular injuries were seen. Complications were not significantly different between groups A and B, or between the three approaches to L5-S1, and trended lower in the latter part of the series as the learning curve progressed.
Conclusions: Inclusion of L5-S1 in OLIF is safe and feasible through three different approaches but likely involves greater operative complexity. In our early experience, inclusion of L5-S1 showed no increase in early complications. This is the first series that reports the use of 3 different oblique approaches to L5-S1. The proposed "facet line" in the preoperative MRI may guide the choice of approach.

World Journal of Orthopedics, 2021
Abstract
BACKGROUND
Oblique lumbar interbody fusion is a mini-open retroperitoneal approach that ... more Abstract
BACKGROUND
Oblique lumbar interbody fusion is a mini-open retroperitoneal approach that uses a wide corridor between the left psoas muscle and the aorta above L5. This approach avoids the limitations of lateral lumbar interbody fusion, is considered less invasive than anterior lumbar interbody fusion, and is similarly effective for indirect decompression and improving lordosis while maintaining a low complication profile. Including L5-S1, when required, adds to these advantages, as this allows single-position surgery. However, variations in vascular anatomy can affect the ease of access to the L5-S1 disc. The nuances of three different oblique anterolateral techniques to access L5-S1 for interbody fusion, namely, left-sided intra-bifurcation, left-sided pre-psoas, and right-sided pre-psoas approaches, are
illustrated using three representative case studies.
CASE SUMMARY
Cases of three patients who underwent multilevel oblique lumbar interbody fusion including L5-S1, using one of the three different techniques, are described. All patients presented with symptomatic degenerative lumbar pathology and failed conservative management prior to surgery. The anatomical considerations that affected the decisions to utilize each approach are discussed. The pros and cons of each approach are also discussed. A parasagittal facet line objectively assesses the relationship between the left common iliac vein and the L5-S1 disc and assists in choosing the approach to L5-S1.
CONCLUSION
Oblique retroperitoneal access to L5-S1 in the lateral decubitus position is possible through three different approaches. The choice of approach to L5-S1 may be individualized based on a patient’s vascular anatomy using preoperative imaging. While most surgeons will rely on their experience and comfort level in choosing the approach, this article elucidates the nuances of each technique.
ped spine by Chirag Berry

Asian Spine Journal, 2021
To determine whether implant density impact three-dimensional deformity correction in posterior s... more To determine whether implant density impact three-dimensional deformity correction in posterior spinal fusion (PSF) without Ponte osteotomies (POs) for patients with Lenke 1 and 2 adolescent idiopathic scoliosis (AIS). Overview of Literature: Currently, the optimal pedicle screw (PS) density for flexible moderate-sized thoracic AIS curve correction is still controversial. There are limited data regarding the impact of implant density on three-dimensional correction in PSF without the use of PO for thoracic AIS surgery. Methods: A database of patients with AIS with Lenke 1 and 2 curves treated with PSF without PO and instrumented with PSs and ≥2-year follow-up was reviewed. The preoperative, immediate, and final follow-up postoperative radiographs were analyzed. The correlation between PS density and the following factors were determined: major curve correction (MCC), correction index (CI; MCC/ curve flexibility), kyphosis angle change, and rib index (RI) correction. Then, patients were divided into low-density (LD) and highdensity (HD) groups according to mean PS density for the entire cohort (1.5 PS per level). Demographics and radiographic and clinical outcomes were compared between groups. Results: The study included 99 patients with Lenke 1 and 23 patients with Lenke 2 AIS. The average MCC was 67.2%. There was no correlation between screw density and these parameters: MCC (r=0.10, p=0.26), CI (r=0.16, p=0.07), change in T2-T12 kyphosis angle (r=−0.13, p=0.14), and RI correction (r=−0.09, p=0.37). Demographic and preoperative radiographic parameters were similar between the LD and HD groups. At the latest follow-up, there were no differences between the two groups in regard to MCC, CI, change in T2-T12 kyphosis angle, RI correction, and Scoliosis Research Society-30 scores (all p>0.05). Conclusions: This study revealed no significant correlation between screw density and curve correction in any planes. HD construct may not provide better deformity correction in patients with flexible and moderate thoracic AIS undergoing PSF without PO.

Journal of Pediatric Orthopaedics, 2017
Background: Spinal deformities associated with neurofibromatosis type 1 (NF1) often have an early... more Background: Spinal deformities associated with neurofibromatosis type 1 (NF1) often have an early onset. These curves frequently develop dysplastic features. Rapid progression is common, and is often difficult to control with casting or bracing. Spinal fusion at a young age can potentially interfere with chest and trunk growth. Growing rods (GRs) have been used in early-onset scoliosis (EOS) effectively. The purpose of this study was to evaluate GR use in NF1.
Methods: Retrospective data collection was performed from a multicenter EOS database with additional patients from our own institute. Each patient had a genetic diagnosis of NF1 and was treated with GR. Results were compared with reported results of GR in EOS in the literature.
Results: Fourteen patients from 5 centers underwent a total of 71 procedures with an average follow-up of 54 months. Mean age at surgery was 6.8 years. Means of initial and final curves were 74 and 36 degrees, respectively (51% correction). Spine grew at an average of 39 mm (11.2 mm per year). Implant-related complications were the most common (8/14, 57%), including failure of proximal construct (5/14), rod breakage (2/14), and prominent implants (1/14). There was no significant difference between screws and hooks as proximal anchors (Fischer test). Two patients had deep infection that needed debridement.
Conclusions: This retrospective pooled data study is the first report on the treatment of early-onset NF1 scoliosis with GRs. The use of GRs in these patients effectively controls the spinal deformity and facilitates growth of the spine. The complications were no greater than those seen in other conditions causing EOS. Failure of proximal anchors was found to be the most common complication.
spine trauma by Chirag Berry

The Spine Journal, 2014
Background context-Motor vehicle collisions (MVC) are a leading cause of thoracic and lumbar (T a... more Background context-Motor vehicle collisions (MVC) are a leading cause of thoracic and lumbar (T and L) spine injuries. Mechanisms of injury in vehicular crashes that result in thoracic and lumbar fractures and the spectrum of injury in these occupants have not been extensively studied in the literature.
Purpose-The objective was to investigate the patterns of T and L spine injury following MVC; correlate these patterns with restraint use, crash characteristics and demographic variables; and study the associations of these injuries with general injury morbidity and fatality.
Study design/Setting-Retrospective study of a prospectively gathered database.
Patient sample-Six hundred and thirty-one occupants with T and L (T1-L5) spine injuries from 4572 occupants included in the Crash Injury Research and Engineering Network (CIREN) database between 1996 and 2011.
Outcome measures-No clinical outcome measures were evaluated in this study.
Methods-The CIREN database includes moderate to severely injured occupants from MVC involving vehicles manufactured recently. Demographic, injury and crash data from each patient was analyzed for correlations between pattern of T and L spine injury, associated extra-spinal injuries and overall injury severity score (ISS), type and use of seat belts, and other crash characteristics. T and L spine injury pattern was categorized using a modified Denis classification, to include extension injuries as a separate entity.
Results-T and L spine injuries were identified in 631 of 4572 vehicle occupants, of whom 299 sustained major injuries (including 21 extension injuries) and 332 sustained minor injuries. Flexion-distraction injuries were more prevalent in children and young adults, and extension injuries in older adults (mean age 65.7 years). Occupants with extension injuries had a mean BMI of 36.0 and a fatality rate of 23.8%, much higher than the fatality rate for the entire cohort (10.9%). The most frequent extra-spinal injuries (Abbreviated Injury Scale grade 2 or more) associated with T and L spine injuries involved the chest (seen in 65.6% of 631 occupants). In contrast to occupants with major T and L spine injuries, those with minor T and L spine injuries showed a strikingly greater association with pelvic and abdominal injuries. Occupants with minor T and L spine injuries had a higher mean ISS (27.1) than those with major T and L spine injuries (25.6). Among occupants wearing a three-point seat belt, 35.3% sustained T and L spine injuries, while only 11.6% of the unbelted occupants sustained T and L spine injuries. Three-point belted individuals were more likely to sustain burst fractures, while two-point belted occupants sustained flexion-distraction injuries most often, and unbelted occupants had a predilection for fracture-dislocations of the T and L spine. Three-point seat belts were protective against neurologic injury, higher ISS and fatality.
Conclusions—T and L spine fracture patterns are influenced by age of occupant and type and use of seat belts. Despite a reduction in overall injury severity and mortality, seat belt use is associated with an increased incidence of T and L spine fractures. Minor T and L spine fractures were associated with an increased likelihood of pelvic and abdominal injuries and higher ISS scores, demonstrating their importance in predicting overall injury severity. Extension injuries occurred in older, obese individuals, and were associated with a high fatality rate. Future advancements in automobile safety engineering should address the need to reduce T and L spine injuries in belted occupants.

Spine, Jan 30, 2015
Retrospective study of a prospectively gathered database. To investigate the incidence and patter... more Retrospective study of a prospectively gathered database. To investigate the incidence and pattern of T and L spine injuries among elderly subjects involved in MVC. Adults age 65 and older currently constitute more than 16% of all licensed drivers. Despite driving less than the young, older drivers are involved in a higher proportion of crashes. Notwithstanding the safety features in modern vehicles, 15.8-51% of all thoracic and lumbar (T and L) spine injuries result from motor vehicle collisions (MVC). CIREN database is a prospectively maintained, multi-centered database that enrolls MVC occupants with moderate to severe injuries. It was queried for T and L spine injuries in subjects 65 and older. One hundred and forty-two CIREN files for all elderly individuals were reviewed for demographic, injury and crash data. Each occupant's T and L injury was categorized using a modified Denis classification. Of 661 elderly subjects, 142 (21.48%) sustained T and L spine injuries. Of the ...

Acta orthopaedica Belgica, 2013
L5S1 fracture-dislocations are rare three-column injuries. The infrequency of this injury has led... more L5S1 fracture-dislocations are rare three-column injuries. The infrequency of this injury has led to a lack of a universally accepted treatment strategy. Transforaminal lumbar interbody fusion (TLIF) has been shown to be an effective approach for interbody fusion in degenerative indications, but has not been previously reported in the operative management of traumatic lumbosacral dislocation. The authors report a case of traumatic L5S1 fracture-dislocation in a 30-year-old male, presenting with a right-sided L5 neurologic deficit, following a street sweeper accident. Imaging revealed an L5S1 fracture-dislocation with fracture of the S1 body. Open reduction with TLIF and L5S1 posterolateral instrumented fusion was carried out within 24 hours of injury. Excellent reduction was obtained, and maintained at long-term follow-up, with complete resolution of pain and neurologic deficit. In this patient, L5S1 fracture-dislocation was treated successfully, with an excellent outcome, with a si...

Acta Orthopaedica Belgica, Feb 1, 2013
L5S1 fracture-dislocations are rare three-column injuries. The infrequency of this injury has led... more L5S1 fracture-dislocations are rare three-column injuries. The infrequency of this injury has led to a lack of a universally accepted treatment strategy. Transforaminal lumbar interbody fusion (TLIF) has been shown to be an effective approach for interbody fusion in degenerative indications, but has not been previously reported in the operative management of traumatic lumbosacral dislocation. The authors report a case of traumatic L5S1 fracture-dislocation in a 30-year-old male, presenting with a right-sided L5 neurologic deficit, following a street sweeper accident. Imaging revealed an L5S1 fracture-dislocation with fracture of the S1 body. Open reduction with TLIF and L5S1 posterolateral instrumented fusion was carried out within 24 hours of injury. Excellent reduction was obtained, and maintained at long-term follow-up, with complete resolution of pain and neurologic deficit. In this patient, L5S1 fracture-dislocation was treated successfully, with an excellent outcome, with a single level TLIF and instrumented posterolateral fusion at L5S1.

The Spine Journal, 2014
Motor vehicle collisions (MVC) are a leading cause of thoracic and lumbar (T and L) spine injurie... more Motor vehicle collisions (MVC) are a leading cause of thoracic and lumbar (T and L) spine injuries. Mechanisms of injury in vehicular crashes that result in thoracic and lumbar fractures and the spectrum of injury in these occupants have not been extensively studied in the literature. The objective was to investigate the patterns of T and L spine injuries after MVC; correlate these patterns with restraint use, crash characteristics, and demographic variables; and study the associations of these injuries with general injury morbidity and fatality. The study design is a retrospective study of a prospectively gathered database. Six hundred thirty-one occupants with T and L (T1-L5) spine injuries from 4,572 occupants included in the Crash Injury Research and Engineering Network (CIREN) database between 1996 and 2011 were included in this study. No clinical outcome measures were evaluated in this study. The CIREN database includes moderate to severely injured occupants from MVC involving vehicles manufactured recently. Demographic, injury, and crash data from each patient were analyzed for correlations between patterns of T and L spine injuries, associated extraspinal injuries and overall injury severity score (ISS), type and use of seat belts, and other crash characteristics. T and L spine injuries patterns were categorized using a modified Denis&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; classification to include extension injuries as a separate entity. T and L spine injuries were identified in 631 of 4,572 vehicle occupants, of whom 299 sustained major injuries (including 21 extension injuries) and 332 sustained minor injuries. Flexion-distraction injuries were more prevalent in children and young adults and extension injuries in older adults (mean age, 65.7 years). Occupants with extension injuries had a mean body mass index of 36.0 and a fatality rate of 23.8%, much higher than the fatality rate for the entire cohort (10.9%). The most frequent extraspinal injuries (Abbreviated Injury Scale Grade 2 or more) associated with T and L spine injuries involved the chest (seen in 65.6% of 631 occupants). In contrast to occupants with major T and L spine injuries, those with minor T and L spine injuries showed a strikingly greater association with pelvic and abdominal injuries. Occupants with minor T and L spine injuries had a higher mean ISS (27.1) than those with major T and L spine injuries (25.6). Among occupants wearing a three-point seat belt, 35.3% sustained T and L spine injuries, whereas only 11.6% of the unbelted occupants sustained T and L spine injuries. Three-point belted individuals were more likely to sustain burst fractures, whereas two-point belted occupants sustained flexion-distraction injuries most often and unbelted occupants had a predilection for fracture-dislocations of the T and L spines. Three-point seat belts were protective against neurologic injury, higher ISS, and fatality. T and L spine fracture patterns are influenced by the age of occupant and type and use of seat belts. Despite a reduction in overall injury severity and mortality, seat belt use is associated with an increased incidence of T and L spine fractures. Minor T and L spine fractures were associated with an increased likelihood of pelvic and abdominal injuries and higher ISSs, demonstrating their importance in predicting overall injury severity. Extension injuries occurred in older obese individuals and were associated with a high fatality rate. Future advancements in automobile safety engineering should address the need to reduce T and L spine injuries in belted occupants.
Seminars in Spine Surgery, 2013
A B S T R A C T Initial management, beginning at the scene of the accident, plays a pivotal role ... more A B S T R A C T Initial management, beginning at the scene of the accident, plays a pivotal role in determining the long-term prognosis of patients with cervical spine injury. Early and appropriate measures increase the likelihood of neurological recovery and subsequently reduce complications from prolonged immobilization and recumbency. This manuscript discusses the prehospital and hospital management of a patient with cervical spine injury, including the techniques of immobilization, initial clinicoradiographic evaluation, the current consensus on "clearance" of the cervical spine, medical management of spinal cord injuries, and the issue of timing of surgery.
Seminars in Spine Surgery, 2013
Seminars in Spine Surgery, 2013
Initial management, beginning at the scene of the accident, plays a pivotal role in determining t... more Initial management, beginning at the scene of the accident, plays a pivotal role in determining the long-term prognosis of patients with cervical spine injury. Early and appropriate measures increase the likelihood of neurological recovery and subsequently reduce complications from prolonged immobilization and recumbency. This manuscript discusses the prehospital and hospital management of a patient with cervical spine injury, including the techniques of immobilization, initial clinicoradiographic evaluation, the current consensus on "clearance" of the cervical spine, medical management of spinal cord injuries, and the issue of timing of surgery.
Seminars in Spine Surgery, 2013
cervical degen by Chirag Berry
Seminars in Spine Surgery, 2014
ABSTRACT The surgical management of multi-level cervical spondylotic myelopathy (CSM) continues t... more ABSTRACT The surgical management of multi-level cervical spondylotic myelopathy (CSM) continues to garner debate within the spine community with regards to optimal management. Options include anterior and posterior decompression with several options available to the surgeon in either approach. The objective of this article is to review the indications, surgical technique, and outcomes of laminectomy with fusion and instrumentation in the management of multi-level CSM.
Seminars in Spine Surgery, 2014
ABSTRACT The surgical management of multi-level cervical spondylotic myelopathy (CSM) continues t... more ABSTRACT The surgical management of multi-level cervical spondylotic myelopathy (CSM) continues to garner debate within the spine community with regards to optimal management. Options include anterior and posterior decompression with several options available to the surgeon in either approach. The objective of this article is to review the indications, surgical technique, and outcomes of laminectomy with fusion and instrumentation in the management of multi-level CSM.
Conference Presentations by Chirag Berry

POSNA Annual Meeting, 2015
LOE-Prognostic-Level II Purpose: Thoracolumbar (TL) spine injury patterns in the pediatric popula... more LOE-Prognostic-Level II Purpose: Thoracolumbar (TL) spine injury patterns in the pediatric population differ considerably from adults. Very few studies have investigated the relationship between vehicle safety restraints for children and TL spine fracture patterns. Methods: We used the Crash Investigation Research & Engineering Network (CIREN) database to obtain data on TL spine injury patterns, associated extra-spinal injuries and overall injury severity in pediatric occupants (up to 18 years of age) and correlated with the type and use of seat restraints and crash characteristics. Occupants in child safety carriers (car seats) were excluded. Results: We found 821 pediatric occupants, of which 57 had TL spine injuries (21 minor, 36 major)(age range:39 to 213 months). Age distribution showed a bimodal pattern with a majority of the patients in the 12-18 years age group and 3-6 years age group. Lower lumbar levels (L2-3 to L5-S1) were most frequently involved (63%), compared to the TL junction (T11 to L2) (24%) and thoracic (T1 to T10-11) levels (13%). The most common associated systemic injuries in occupants with major TL spine injuries were abdominal injuries (53%). 'Suboptimally-belted' pediatric occupants, defined as those wearing either a two-point seat belt or a three-point seat belt with the shoulder belt inappropriately worn behind the back or underarm (n=14, age range: 61 to 158 months), showed the highest likelihood of sustaining TL spine injuries (21%). Suboptimally-belted children were most likely to sustain flexion-distraction injuries (73%), while appropriately belted children were most likely to sustain compression fractures (47%), followed by flexion-distraction injuries (35%) and burst fractures (18%). The likelihood of neurological injury was highest in the suboptimally belted group (36%), followed by the unbelted group (33%) and appropriately belted group (16%). Side impact collisions were more often associated with a higher overall injury severity score (ISS) and fatality as compared to frontal impacts, irrespective of use of seat belts. Conclusion: Transition from child safety carriers to booster seats may be responsible for the spike in the 3-6 years age group. The classic "seat belt injury" described in association with 'lap-belt only' configuration is still common in children in spite of universal change to 3-point seat belts in vehicles manufactured in the last few decades. Certain morphologic features in children (immature iliac bones, flexible lumbar spine, and a higher center of gravity) allow 'submarining' under the lap belt more readily than in adults, making them prone to flexion-distraction injuries of the lumbar spine. Inappropriate use or lack of use of the shoulder belt is common in children, and can lead to a higher likelihood of flexion-distraction TL spine injuries, neurologic deficits, and associated abdominal injuries. Understanding the mechanisms of spinal injuries in children is important to stimulate further advances in child safety restraints.
Papers by Chirag Berry
Journal of Orthopaedic Science, 2022

European Spine Journal, Jan 8, 2021
Purpose While posterior-alone techniques have been successful for most pediatric spinal deformiti... more Purpose While posterior-alone techniques have been successful for most pediatric spinal deformities, anterior spinal release may be useful for severe rigid deformities. Traditional lateral-positioned video-assisted thoracoscopic surgical release (VATSR) followed by prone posterior spinal fusion (PSF) has been criticized for adding extensive operative morbidity. We aimed to reduce its disadvantages by performing prone VATSR and PSF simultaneously and evaluate its long-term outcomes. Methods All consecutive patients from 1991 to 2012 undergoing VATSR and PSF at one institution were retrospectively reviewed. The inclusion criteria comprised severe rigid thoracic scoliosis (> 70°, bending correction > 45°) or kyphosis (> 75°, bolster correction > 45°), and a minimum 2 year follow-up. Demographics, operative data, hospital stay, and radiographic correction data were compared between patients who had undergone sequential VATSR followed by PSF and those who had undergone these procedures simultaneously. Results Of 153 patients who had undergone VATSR and PSF, 53 met the inclusion criteria (31 sequential, 22 simultaneous; average follow-up, 50 [range, 24–86] months). Age, preoperative measurements and flexibility, and perioperative complications did not differ significantly. The simultaneous group showed significantly lower operative time (449 vs. 618 min), blood loss (1039 vs. 1906 cc), and hospital stay (6.3 vs. 8.5 days) (all, p < 0.05). Postoperative radiographic correction and maintenance at the final follow-up showed a non-significant trend favoring the simultaneous group. Conclusion Our simultaneous prone VATSR and PSF technique showed significantly lower operative time, blood loss, and hospital stay compared with the traditional sequential VATSR and PSF method, suggesting its value in treating rigid deformities.
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olif by Chirag Berry
aorta and the left-sided psoas muscle to access the lumbar spine allowing a minimally invasive approach
for interbody fusion with lower associated morbidity. As this approach is gaining popularity among spine
surgeons, it is important to understand the potential pitfalls that may arise in patients with congenital
anomalies of the vascular anatomy.
Case description: We present a case of a persistent left-sided inferior vena cava (IVC) affecting the side
of approach in a patient undergoing lumbar interbody fusion through an oblique pre-psoas
retroperitoneal approach. Preoperative imaging of our patient revealed a persistent left-sided inferior
vena cava with a wide interval between the aorta and the right-sided psoas allowing us a right-sided
oblique approach.
Conclusions: Thorough preoperative imaging evaluation is essential to identify vascular anomalies that
may hinder oblique pre-psoas retroperitoneal approach to the lumbar spine. Although rare, double IVC
or isolated Left IVC may complicate the oblique approach.
Purpose: Our objectives were to evaluate our early experience with the safety of including L5-S1 in OLIF using 3 different approach techniques, as well as to compare early complications between OLIF with and without L5-S1 inclusion.
Study design: Retrospective cohort study.
Patient sample: Of the 87 patients who underwent lumbar interbody fusion at 167 spinal levels via an OLIF approach, 19 included L5-S1 (group A) and 68 did not (group B).
Outcome measures: Demographics, levels fused, indications, operative time (ORT), estimated blood loss (EBL), vascular ligation, intraoperative blood transfusion, length of stay (LOS), discharge to rehabilitation facility, and complications (intraoperative, early ≤90 days, and delayed >90 days) were retrospectively assessed and compared between the groups.
Methods: A retrospective chart and imaging review of all consecutive patients who underwent OLIF at a single institution was performed. Indications for OLIF included symptomatic lumbar degenerative stenosis, deformity, and spondylolisthesis. The L5-S1 level, when included, was approached via one of the following 3 techniques: (1) a left-sided intrabifurcation approach; (2) left-sided prepsoas approach; and (3) right-sided prepsoas approach. Vascular anatomic variations at the lumbosacral junction were evaluated using the preoperative magnetic resonance imaging (MRI), and a "facet line" was proposed to assess this relationship. A minimum of 6 months of follow-up data were assessed for approach-related morbidities.
Results: Demographics and operative indications were similar between the groups. The mean follow-up was 10.8 (6-36) months. ORT was significantly longer in group A than in group B (322 vs. 256.3 min, respectively; p=.001); however, no difference in ORT between the two groups was found in the subanalyses for 2- and 3-level surgeries. Differences in EBL (260 vs. 207.91 cc, p=.251) and LOS (2.76 vs. 2.48 days, p=.491) did not reach statistical significance. Ligation of the iliolumbar vein, segmental veins, median sacral vessels, or any vascular structure, as needed for adequate exposure, was required in 13 (68.4%) patients from group A and 4 (5.9%) from group B (p<.00001). Two patients suffered minor vascular injuries (1 in each group); however, no major vascular injuries were seen. Complications were not significantly different between groups A and B, or between the three approaches to L5-S1, and trended lower in the latter part of the series as the learning curve progressed.
Conclusions: Inclusion of L5-S1 in OLIF is safe and feasible through three different approaches but likely involves greater operative complexity. In our early experience, inclusion of L5-S1 showed no increase in early complications. This is the first series that reports the use of 3 different oblique approaches to L5-S1. The proposed "facet line" in the preoperative MRI may guide the choice of approach.
BACKGROUND
Oblique lumbar interbody fusion is a mini-open retroperitoneal approach that uses a wide corridor between the left psoas muscle and the aorta above L5. This approach avoids the limitations of lateral lumbar interbody fusion, is considered less invasive than anterior lumbar interbody fusion, and is similarly effective for indirect decompression and improving lordosis while maintaining a low complication profile. Including L5-S1, when required, adds to these advantages, as this allows single-position surgery. However, variations in vascular anatomy can affect the ease of access to the L5-S1 disc. The nuances of three different oblique anterolateral techniques to access L5-S1 for interbody fusion, namely, left-sided intra-bifurcation, left-sided pre-psoas, and right-sided pre-psoas approaches, are
illustrated using three representative case studies.
CASE SUMMARY
Cases of three patients who underwent multilevel oblique lumbar interbody fusion including L5-S1, using one of the three different techniques, are described. All patients presented with symptomatic degenerative lumbar pathology and failed conservative management prior to surgery. The anatomical considerations that affected the decisions to utilize each approach are discussed. The pros and cons of each approach are also discussed. A parasagittal facet line objectively assesses the relationship between the left common iliac vein and the L5-S1 disc and assists in choosing the approach to L5-S1.
CONCLUSION
Oblique retroperitoneal access to L5-S1 in the lateral decubitus position is possible through three different approaches. The choice of approach to L5-S1 may be individualized based on a patient’s vascular anatomy using preoperative imaging. While most surgeons will rely on their experience and comfort level in choosing the approach, this article elucidates the nuances of each technique.
ped spine by Chirag Berry
Methods: Retrospective data collection was performed from a multicenter EOS database with additional patients from our own institute. Each patient had a genetic diagnosis of NF1 and was treated with GR. Results were compared with reported results of GR in EOS in the literature.
Results: Fourteen patients from 5 centers underwent a total of 71 procedures with an average follow-up of 54 months. Mean age at surgery was 6.8 years. Means of initial and final curves were 74 and 36 degrees, respectively (51% correction). Spine grew at an average of 39 mm (11.2 mm per year). Implant-related complications were the most common (8/14, 57%), including failure of proximal construct (5/14), rod breakage (2/14), and prominent implants (1/14). There was no significant difference between screws and hooks as proximal anchors (Fischer test). Two patients had deep infection that needed debridement.
Conclusions: This retrospective pooled data study is the first report on the treatment of early-onset NF1 scoliosis with GRs. The use of GRs in these patients effectively controls the spinal deformity and facilitates growth of the spine. The complications were no greater than those seen in other conditions causing EOS. Failure of proximal anchors was found to be the most common complication.
spine trauma by Chirag Berry
Purpose-The objective was to investigate the patterns of T and L spine injury following MVC; correlate these patterns with restraint use, crash characteristics and demographic variables; and study the associations of these injuries with general injury morbidity and fatality.
Study design/Setting-Retrospective study of a prospectively gathered database.
Patient sample-Six hundred and thirty-one occupants with T and L (T1-L5) spine injuries from 4572 occupants included in the Crash Injury Research and Engineering Network (CIREN) database between 1996 and 2011.
Outcome measures-No clinical outcome measures were evaluated in this study.
Methods-The CIREN database includes moderate to severely injured occupants from MVC involving vehicles manufactured recently. Demographic, injury and crash data from each patient was analyzed for correlations between pattern of T and L spine injury, associated extra-spinal injuries and overall injury severity score (ISS), type and use of seat belts, and other crash characteristics. T and L spine injury pattern was categorized using a modified Denis classification, to include extension injuries as a separate entity.
Results-T and L spine injuries were identified in 631 of 4572 vehicle occupants, of whom 299 sustained major injuries (including 21 extension injuries) and 332 sustained minor injuries. Flexion-distraction injuries were more prevalent in children and young adults, and extension injuries in older adults (mean age 65.7 years). Occupants with extension injuries had a mean BMI of 36.0 and a fatality rate of 23.8%, much higher than the fatality rate for the entire cohort (10.9%). The most frequent extra-spinal injuries (Abbreviated Injury Scale grade 2 or more) associated with T and L spine injuries involved the chest (seen in 65.6% of 631 occupants). In contrast to occupants with major T and L spine injuries, those with minor T and L spine injuries showed a strikingly greater association with pelvic and abdominal injuries. Occupants with minor T and L spine injuries had a higher mean ISS (27.1) than those with major T and L spine injuries (25.6). Among occupants wearing a three-point seat belt, 35.3% sustained T and L spine injuries, while only 11.6% of the unbelted occupants sustained T and L spine injuries. Three-point belted individuals were more likely to sustain burst fractures, while two-point belted occupants sustained flexion-distraction injuries most often, and unbelted occupants had a predilection for fracture-dislocations of the T and L spine. Three-point seat belts were protective against neurologic injury, higher ISS and fatality.
Conclusions—T and L spine fracture patterns are influenced by age of occupant and type and use of seat belts. Despite a reduction in overall injury severity and mortality, seat belt use is associated with an increased incidence of T and L spine fractures. Minor T and L spine fractures were associated with an increased likelihood of pelvic and abdominal injuries and higher ISS scores, demonstrating their importance in predicting overall injury severity. Extension injuries occurred in older, obese individuals, and were associated with a high fatality rate. Future advancements in automobile safety engineering should address the need to reduce T and L spine injuries in belted occupants.
cervical degen by Chirag Berry
Conference Presentations by Chirag Berry
Papers by Chirag Berry
aorta and the left-sided psoas muscle to access the lumbar spine allowing a minimally invasive approach
for interbody fusion with lower associated morbidity. As this approach is gaining popularity among spine
surgeons, it is important to understand the potential pitfalls that may arise in patients with congenital
anomalies of the vascular anatomy.
Case description: We present a case of a persistent left-sided inferior vena cava (IVC) affecting the side
of approach in a patient undergoing lumbar interbody fusion through an oblique pre-psoas
retroperitoneal approach. Preoperative imaging of our patient revealed a persistent left-sided inferior
vena cava with a wide interval between the aorta and the right-sided psoas allowing us a right-sided
oblique approach.
Conclusions: Thorough preoperative imaging evaluation is essential to identify vascular anomalies that
may hinder oblique pre-psoas retroperitoneal approach to the lumbar spine. Although rare, double IVC
or isolated Left IVC may complicate the oblique approach.
Purpose: Our objectives were to evaluate our early experience with the safety of including L5-S1 in OLIF using 3 different approach techniques, as well as to compare early complications between OLIF with and without L5-S1 inclusion.
Study design: Retrospective cohort study.
Patient sample: Of the 87 patients who underwent lumbar interbody fusion at 167 spinal levels via an OLIF approach, 19 included L5-S1 (group A) and 68 did not (group B).
Outcome measures: Demographics, levels fused, indications, operative time (ORT), estimated blood loss (EBL), vascular ligation, intraoperative blood transfusion, length of stay (LOS), discharge to rehabilitation facility, and complications (intraoperative, early ≤90 days, and delayed >90 days) were retrospectively assessed and compared between the groups.
Methods: A retrospective chart and imaging review of all consecutive patients who underwent OLIF at a single institution was performed. Indications for OLIF included symptomatic lumbar degenerative stenosis, deformity, and spondylolisthesis. The L5-S1 level, when included, was approached via one of the following 3 techniques: (1) a left-sided intrabifurcation approach; (2) left-sided prepsoas approach; and (3) right-sided prepsoas approach. Vascular anatomic variations at the lumbosacral junction were evaluated using the preoperative magnetic resonance imaging (MRI), and a "facet line" was proposed to assess this relationship. A minimum of 6 months of follow-up data were assessed for approach-related morbidities.
Results: Demographics and operative indications were similar between the groups. The mean follow-up was 10.8 (6-36) months. ORT was significantly longer in group A than in group B (322 vs. 256.3 min, respectively; p=.001); however, no difference in ORT between the two groups was found in the subanalyses for 2- and 3-level surgeries. Differences in EBL (260 vs. 207.91 cc, p=.251) and LOS (2.76 vs. 2.48 days, p=.491) did not reach statistical significance. Ligation of the iliolumbar vein, segmental veins, median sacral vessels, or any vascular structure, as needed for adequate exposure, was required in 13 (68.4%) patients from group A and 4 (5.9%) from group B (p<.00001). Two patients suffered minor vascular injuries (1 in each group); however, no major vascular injuries were seen. Complications were not significantly different between groups A and B, or between the three approaches to L5-S1, and trended lower in the latter part of the series as the learning curve progressed.
Conclusions: Inclusion of L5-S1 in OLIF is safe and feasible through three different approaches but likely involves greater operative complexity. In our early experience, inclusion of L5-S1 showed no increase in early complications. This is the first series that reports the use of 3 different oblique approaches to L5-S1. The proposed "facet line" in the preoperative MRI may guide the choice of approach.
BACKGROUND
Oblique lumbar interbody fusion is a mini-open retroperitoneal approach that uses a wide corridor between the left psoas muscle and the aorta above L5. This approach avoids the limitations of lateral lumbar interbody fusion, is considered less invasive than anterior lumbar interbody fusion, and is similarly effective for indirect decompression and improving lordosis while maintaining a low complication profile. Including L5-S1, when required, adds to these advantages, as this allows single-position surgery. However, variations in vascular anatomy can affect the ease of access to the L5-S1 disc. The nuances of three different oblique anterolateral techniques to access L5-S1 for interbody fusion, namely, left-sided intra-bifurcation, left-sided pre-psoas, and right-sided pre-psoas approaches, are
illustrated using three representative case studies.
CASE SUMMARY
Cases of three patients who underwent multilevel oblique lumbar interbody fusion including L5-S1, using one of the three different techniques, are described. All patients presented with symptomatic degenerative lumbar pathology and failed conservative management prior to surgery. The anatomical considerations that affected the decisions to utilize each approach are discussed. The pros and cons of each approach are also discussed. A parasagittal facet line objectively assesses the relationship between the left common iliac vein and the L5-S1 disc and assists in choosing the approach to L5-S1.
CONCLUSION
Oblique retroperitoneal access to L5-S1 in the lateral decubitus position is possible through three different approaches. The choice of approach to L5-S1 may be individualized based on a patient’s vascular anatomy using preoperative imaging. While most surgeons will rely on their experience and comfort level in choosing the approach, this article elucidates the nuances of each technique.
Methods: Retrospective data collection was performed from a multicenter EOS database with additional patients from our own institute. Each patient had a genetic diagnosis of NF1 and was treated with GR. Results were compared with reported results of GR in EOS in the literature.
Results: Fourteen patients from 5 centers underwent a total of 71 procedures with an average follow-up of 54 months. Mean age at surgery was 6.8 years. Means of initial and final curves were 74 and 36 degrees, respectively (51% correction). Spine grew at an average of 39 mm (11.2 mm per year). Implant-related complications were the most common (8/14, 57%), including failure of proximal construct (5/14), rod breakage (2/14), and prominent implants (1/14). There was no significant difference between screws and hooks as proximal anchors (Fischer test). Two patients had deep infection that needed debridement.
Conclusions: This retrospective pooled data study is the first report on the treatment of early-onset NF1 scoliosis with GRs. The use of GRs in these patients effectively controls the spinal deformity and facilitates growth of the spine. The complications were no greater than those seen in other conditions causing EOS. Failure of proximal anchors was found to be the most common complication.
Purpose-The objective was to investigate the patterns of T and L spine injury following MVC; correlate these patterns with restraint use, crash characteristics and demographic variables; and study the associations of these injuries with general injury morbidity and fatality.
Study design/Setting-Retrospective study of a prospectively gathered database.
Patient sample-Six hundred and thirty-one occupants with T and L (T1-L5) spine injuries from 4572 occupants included in the Crash Injury Research and Engineering Network (CIREN) database between 1996 and 2011.
Outcome measures-No clinical outcome measures were evaluated in this study.
Methods-The CIREN database includes moderate to severely injured occupants from MVC involving vehicles manufactured recently. Demographic, injury and crash data from each patient was analyzed for correlations between pattern of T and L spine injury, associated extra-spinal injuries and overall injury severity score (ISS), type and use of seat belts, and other crash characteristics. T and L spine injury pattern was categorized using a modified Denis classification, to include extension injuries as a separate entity.
Results-T and L spine injuries were identified in 631 of 4572 vehicle occupants, of whom 299 sustained major injuries (including 21 extension injuries) and 332 sustained minor injuries. Flexion-distraction injuries were more prevalent in children and young adults, and extension injuries in older adults (mean age 65.7 years). Occupants with extension injuries had a mean BMI of 36.0 and a fatality rate of 23.8%, much higher than the fatality rate for the entire cohort (10.9%). The most frequent extra-spinal injuries (Abbreviated Injury Scale grade 2 or more) associated with T and L spine injuries involved the chest (seen in 65.6% of 631 occupants). In contrast to occupants with major T and L spine injuries, those with minor T and L spine injuries showed a strikingly greater association with pelvic and abdominal injuries. Occupants with minor T and L spine injuries had a higher mean ISS (27.1) than those with major T and L spine injuries (25.6). Among occupants wearing a three-point seat belt, 35.3% sustained T and L spine injuries, while only 11.6% of the unbelted occupants sustained T and L spine injuries. Three-point belted individuals were more likely to sustain burst fractures, while two-point belted occupants sustained flexion-distraction injuries most often, and unbelted occupants had a predilection for fracture-dislocations of the T and L spine. Three-point seat belts were protective against neurologic injury, higher ISS and fatality.
Conclusions—T and L spine fracture patterns are influenced by age of occupant and type and use of seat belts. Despite a reduction in overall injury severity and mortality, seat belt use is associated with an increased incidence of T and L spine fractures. Minor T and L spine fractures were associated with an increased likelihood of pelvic and abdominal injuries and higher ISS scores, demonstrating their importance in predicting overall injury severity. Extension injuries occurred in older, obese individuals, and were associated with a high fatality rate. Future advancements in automobile safety engineering should address the need to reduce T and L spine injuries in belted occupants.