Эчтәлеккә күчү

SPN

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SPN
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген Лейкосиалин[d][1]
Молекуляр функция transmembrane signaling receptor activity[d][2], Hsp70 protein binding[d][3] һәм heat shock protein binding[d][3][4]
Күзәнәк компоненты мембрана өлеше[d][4], мембрана[d][4][5], күзәнәк мембранасы[d][4], күзәнәк мембранасы өлеше[d][6][4], базаль мембрана[d][4], күзәнәк өслеге[d][7], uropod[d][4], экзосома[d][8], наружная сторона клеточной мембраны[d][4] һәм күзәнәк тышындагы мохит[d][9]
Биологик процесс negative regulation of cell adhesion[d][10][4], positive regulation of protein phosphorylation[d][4], negative regulation of type IV hypersensitivity[d][4], response to protozoan[d][4], T cell costimulation[d][4], negative thymic T cell selection[d][4], хемотаксис[d][10], establishment or maintenance of cell polarity[d][10], cellular defense response[d][2], cell surface receptor signaling pathway[d][4], negative regulation of T cell proliferation[d][4], defense response to bacterium[d][4][9], иммун җавап[d][6], positive regulation of T cell proliferation[d][4], regulation of immune response[d][4], apoptotic signaling pathway[d][4], regulation of defense response to virus[d][4], negative regulation of T cell activation[d][4], leukocyte migration[d][4] һәм передача сигнала[d][6]

SPN (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[11][12]

  1. 1 2 UniProt
  2. 1 2 Burakoff S. J., Bierer B. E., Hahn W. C. CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1 // Nature / M. SkipperNPG, Springer Science+Business Media, 1991. — ISSN 1476-4687; 0028-0836doi:10.1038/354233A0PMID:1683685
  3. 1 2 Tyler B M Hickey, Ziltener H. J., Speert D. P. et al. Mycobacterium tuberculosis employs Cpn60.2 as an adhesin that binds CD43 on the macrophage surface // Cellular MicrobiologyWiley-Blackwell, Hindawi Publishing Corporation, 2010. — ISSN 1462-5814; 1462-5822doi:10.1111/J.1462-5822.2010.01496.XPMID:20633027
  4. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 GOA
  5. Lippert D. Defining the membrane proteome of NK cells // J. Mass Spectrom.Wiley, 2010. — ISSN 1076-5174; 1096-9888doi:10.1002/JMS.1696PMID:19946888
  6. 1 2 3 Burakoff S. J., Bierer B. E., E Remold-O'Donnell Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome // Nature / M. SkipperNPG, Springer Science+Business Media, 1991. — ISSN 1476-4687; 0028-0836doi:10.1038/350706A0PMID:2023632
  7. Dohmae N. The Lyn kinase C-lobe mediates Golgi export of Lyn through conformation-dependent ACSL3 association // J. Cell Sci.The Company of Biologists, 2010. — ISSN 0021-9533; 1477-9137doi:10.1242/JCS.066266PMID:20605918
  8. Buschow S. I., Stoorvogel W., Wauben M. MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis // Immunology & Cell BiologyWiley, 2010. — ISSN 0818-9641; 1440-1711doi:10.1038/ICB.2010.64PMID:20458337
  9. 1 2 C Fratazzi, N Manjunath, Arbeit R. D. et al. A macrophage invasion mechanism for mycobacteria implicating the extracellular domain of CD43 // J. Exp. Med.Rockefeller University Press, 2000. — ISSN 0022-1007; 1540-9538doi:10.1084/JEM.192.2.183PMID:10899905
  10. 1 2 3 Seveau S, Keller H, FR M. et al. Neutrophil polarity and locomotion are associated with surface redistribution of leukosialin (CD43), an antiadhesive membrane molecule // BloodAmerican Society of Hematology, Elsevier, 2000. — ISSN 0006-4971; 1528-0020PMID:10753822
  11. HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  12. UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)