Jihjong Lee

National Taiwan University, Graduate Institute of Veterinary Clinical Sciences, Faculty Member

National Taiwan University, Veterinary Medicine, Faculty Member

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Veterinarian, Medical Oncologist, Diplomate of Asian College of Veterinary Internal Medicine.
Phone: +886926192939
Address: 153, Keelung Rd. Sec. 3, Da-an Dist
Taipei, Taiwan, 10660

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Robert Hills

Cardiff University

Vivekanand Jha

Fortis Escorts Heart Institute

Maria-Corina Serban

University Of Medicine And Pharmacy Timisoara

Samuel LÉZÉ

École Normale Supérieure de Lyon

Dr Hakim Athar

Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST)

Eszter Banffy

Hungarian Academy of Sciences

Dr Noore Alam Tufani

Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST)

Fatih Hatipoglu

Selcuk University (Selçuk Üniversitesi)

MARIA KRITSEPI-KONSTANTINOU

Aristotle University of Thessaloniki

Abdulrahman Bello (DVM, MSc, PhD)

Usmanu Danfodio University, Sokoto

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Papers by Jihjong Lee

Assessment of temporal association of relapse of canine multicentric lymphoma with components of the CHOP protocol: Is cyclophosphamide the weakest link?

The Veterinary Journal, 2016

Combination chemotherapy, using cyclophosphamide, hydroxydaunorubicin, vincristine and prednisolo... more Combination chemotherapy, using cyclophosphamide, hydroxydaunorubicin, vincristine and prednisolone (CHOP), is the most commonly used treatment for canine lymphoma. Most affected dogs respond during the initial stages of chemotherapy, but many relapse. The aim of this study was to evaluate the relationship between the use of specific chemotherapy drugs and clinical relapse, using the modified Madison-Wisconsin, 25 week chemotherapy protocol. Forty-one of 68 dogs affected with multicentric lymphoma relapsed during the treatment period. Relapse occurred more frequently after the administration of cyclophosphamide (n = 24; P &lt; 0.01), compared with vincristine (n = 9) or doxorubicin (n = 5). Therefore, the therapeutic outcome of traditional CHOP-based chemotherapy might be improved by replacing cyclophosphamide with other cytotoxic drugs.

Field strain feline coronaviruses with small deletions in ORF7b associated with both enteric infection and feline infectious peritonitis

Journal of Feline Medicine & Surgery, 2009

Feline coronavirus (FCoV) varies greatly from causing subclinical or mild enteric infections to f... more Feline coronavirus (FCoV) varies greatly from causing subclinical or mild enteric infections to fatal feline infectious peritonitis (FIP). The open reading frame (ORF) 7b of FCoV has been speculated to play a determining role in virulence as deletions were found to be associated with avirulent viruses. To further clarify the correlation between this gene and FIP, clinical samples from 20 cats that had succumbed to wet-type FIP and 20 clinically healthy FCoV-infected cats were analysed. The ORF7b from the peritoneal/pleural effusions of FIP cats and from the rectal swabs of healthy cats was amplified. Of the 40 FCoVs analysed, 32 were found to have an intact 7b gene whereas eight showed deletions of either three or 12 nucleotides. Surprisingly, among the eight viruses with deletions, three were from FIP diseased cats. These results show that deletions in the ORF7b gene are not constrained to low pathogenicity/enteric biotypes but also associated with pathogenicity/FIP biotypes of FCoV.

Jihjong Lee

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