Background. Frailty is considered highly prevalent in old age and to confer high risk for falls, ... more Background. Frailty is considered highly prevalent in old age and to confer high risk for falls, disability, hospitalization, and mortality. Frailty has been considered synonymous with disability, comorbidity, and other characteristics, but it is recognized that it may have a biologic basis and be a distinct clinical syndrome. A standardized definition has not yet been established.
Meta-analytic techniques were used to determine which predictor domains and actuarial assessment ... more Meta-analytic techniques were used to determine which predictor domains and actuarial assessment instruments were the best predictors of adult offender recidivism. One hundred and thirty-one studies produced 1,141 correlations with recidivism. The strongest predictor domains were criminogenic needs, criminal history/history of antisocial behavior, social achievement, age/gender/race, and family factors. Less robust predictors included intellectual functioning, personal distress factors, and socioeconomic status in the family of origin. Dynamic predictor domains performed at least as well as the static domains. The LSI-R was identified as the most useful actuarial measure. Recommendations for developing sound assessment practices in corrections are provided.
ABSTRACT Network wide broadcasting in Mobile Ad Hoc Networks provides important control and route... more ABSTRACT Network wide broadcasting in Mobile Ad Hoc Networks provides important control and route establishment functionality for a num-ber of unicast and multicast protocols. Considering its wide use as a building block for other network layer protocols, the MANET community ...
Gene targeting was used to create a null allele at the epidermal growth factor receptor locus (Eg... more Gene targeting was used to create a null allele at the epidermal growth factor receptor locus (Egfr). The phenotype was dependent on genetic background. EGFR deficiency on a CF-1 background resulted in peri-implantation death due to degeneration of the inner cell mass. On a 129/Sv background, homozygous mutants died at mid-gestation due to placental defects; on a CD-1 background, the mutants lived for up to 3 weeks and showed abnormalities in skin, kidney, brain, liver, and gastrointestinal tract. The multiple abnormalities associated with EGFR deficiency indicate that the receptor is involved in a wide range of cellular activities.
Previous studies suggested that one or more genes on chromosome 5q21 are responsible for the inhe... more Previous studies suggested that one or more genes on chromosome 5q21 are responsible for the inheritance of familial adenomatous polyposis (FAP) and Gardner's syndrome (GS), and contribute to tumor development in patients with noninherited forms of colorectal cancer. Two genes on 5q21 that are tightly linked to FAP (MCC and APC) were found to be somatically altered in tumors from sporadic colorectal cancer patients. One of the genes (APC) was also found to be altered by point mutation in the germ line of FAP and GS patients. These data suggest that more than one gene on chromosome 5q21 may contribute to colorectal neoplasia, and that mutations of the APC gene can cause both FAP and GS. The identification of these genes should aid in understanding the pathogenesis of colorectal neoplasia and in the diagnosis and counseling of patients with inherited predispositions to colorectal cancer.
Most automatic test pattern generation systems for combinational circuits generate a test for a g... more Most automatic test pattern generation systems for combinational circuits generate a test for a given fault by directly searching a data structure representing the circuit to be tested. The author describes a novel system that divides the problem into two parts: first it constructs a formula expressing the Boolean difference between the unfaulted and faulted circuits. Second, it applies a Boolean satisfiability algorithm to the resulting formula. The novel system can incorporate any of the heuristics used by structural search techniques. It is not only quite general but is able to test or improve untestable every fault in the popular Brglez-Fujiwara test benchmark (Int. Symp. Circuits and Systems, June 1985). Experimental results are presented
Wireless Communications and Mobile Computing, 2002
In the performance evaluation of a protocol for an ad hoc network, the protocol should be tested ... more In the performance evaluation of a protocol for an ad hoc network, the protocol should be tested under realistic conditions including, but not limited to, a sensible transmission range, limited buffer space for the storage of messages, representative data traffic models and realistic movements of the mobile users (i.e. a mobility model). This paper is a survey of mobility models that are used in the simulations of ad hoc networks. We describe several mobility models that represent mobile nodes whose movements are independent of each other (i.e. entity mobility models) and several mobility models that represent mobile nodes whose movements are dependent on each other (i.e. group mobility models). The goal of this paper is to present a number of mobility models in order to offer researchers more informed choices when they are deciding on a mobility model to use in their performance evaluations. Lastly, we present simulation results that illustrate the importance of choosing a mobility model in the simulation of an ad hoc network protocol. Specifically, we illustrate how the performance results of an ad hoc network protocol drastically change as a result of changing the mobility model simulated.
Background. Frailty is considered highly prevalent in old age and to confer high risk for falls, ... more Background. Frailty is considered highly prevalent in old age and to confer high risk for falls, disability, hospitalization, and mortality. Frailty has been considered synonymous with disability, comorbidity, and other characteristics, but it is recognized that it may have a biologic basis and be a distinct clinical syndrome. A standardized definition has not yet been established.
Meta-analytic techniques were used to determine which predictor domains and actuarial assessment ... more Meta-analytic techniques were used to determine which predictor domains and actuarial assessment instruments were the best predictors of adult offender recidivism. One hundred and thirty-one studies produced 1,141 correlations with recidivism. The strongest predictor domains were criminogenic needs, criminal history/history of antisocial behavior, social achievement, age/gender/race, and family factors. Less robust predictors included intellectual functioning, personal distress factors, and socioeconomic status in the family of origin. Dynamic predictor domains performed at least as well as the static domains. The LSI-R was identified as the most useful actuarial measure. Recommendations for developing sound assessment practices in corrections are provided.
ABSTRACT Network wide broadcasting in Mobile Ad Hoc Networks provides important control and route... more ABSTRACT Network wide broadcasting in Mobile Ad Hoc Networks provides important control and route establishment functionality for a num-ber of unicast and multicast protocols. Considering its wide use as a building block for other network layer protocols, the MANET community ...
Gene targeting was used to create a null allele at the epidermal growth factor receptor locus (Eg... more Gene targeting was used to create a null allele at the epidermal growth factor receptor locus (Egfr). The phenotype was dependent on genetic background. EGFR deficiency on a CF-1 background resulted in peri-implantation death due to degeneration of the inner cell mass. On a 129/Sv background, homozygous mutants died at mid-gestation due to placental defects; on a CD-1 background, the mutants lived for up to 3 weeks and showed abnormalities in skin, kidney, brain, liver, and gastrointestinal tract. The multiple abnormalities associated with EGFR deficiency indicate that the receptor is involved in a wide range of cellular activities.
Previous studies suggested that one or more genes on chromosome 5q21 are responsible for the inhe... more Previous studies suggested that one or more genes on chromosome 5q21 are responsible for the inheritance of familial adenomatous polyposis (FAP) and Gardner's syndrome (GS), and contribute to tumor development in patients with noninherited forms of colorectal cancer. Two genes on 5q21 that are tightly linked to FAP (MCC and APC) were found to be somatically altered in tumors from sporadic colorectal cancer patients. One of the genes (APC) was also found to be altered by point mutation in the germ line of FAP and GS patients. These data suggest that more than one gene on chromosome 5q21 may contribute to colorectal neoplasia, and that mutations of the APC gene can cause both FAP and GS. The identification of these genes should aid in understanding the pathogenesis of colorectal neoplasia and in the diagnosis and counseling of patients with inherited predispositions to colorectal cancer.
Most automatic test pattern generation systems for combinational circuits generate a test for a g... more Most automatic test pattern generation systems for combinational circuits generate a test for a given fault by directly searching a data structure representing the circuit to be tested. The author describes a novel system that divides the problem into two parts: first it constructs a formula expressing the Boolean difference between the unfaulted and faulted circuits. Second, it applies a Boolean satisfiability algorithm to the resulting formula. The novel system can incorporate any of the heuristics used by structural search techniques. It is not only quite general but is able to test or improve untestable every fault in the popular Brglez-Fujiwara test benchmark (Int. Symp. Circuits and Systems, June 1985). Experimental results are presented
Wireless Communications and Mobile Computing, 2002
In the performance evaluation of a protocol for an ad hoc network, the protocol should be tested ... more In the performance evaluation of a protocol for an ad hoc network, the protocol should be tested under realistic conditions including, but not limited to, a sensible transmission range, limited buffer space for the storage of messages, representative data traffic models and realistic movements of the mobile users (i.e. a mobility model). This paper is a survey of mobility models that are used in the simulations of ad hoc networks. We describe several mobility models that represent mobile nodes whose movements are independent of each other (i.e. entity mobility models) and several mobility models that represent mobile nodes whose movements are dependent on each other (i.e. group mobility models). The goal of this paper is to present a number of mobility models in order to offer researchers more informed choices when they are deciding on a mobility model to use in their performance evaluations. Lastly, we present simulation results that illustrate the importance of choosing a mobility model in the simulation of an ad hoc network protocol. Specifically, we illustrate how the performance results of an ad hoc network protocol drastically change as a result of changing the mobility model simulated.
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