The Art and Science of Cellular Health
Advancing noninvasive technology to create a new diagnostic standard of care
SignatureDx is reshaping the way we predict, detect, and understand human disease through advanced noninvasive diagnostics
The Importance of Early
Detection & Diagnosis
Medical conditions appear in different forms for each individual, often progressing without any visible symptoms. Silently progressing conditions are not typically detected until they have reached more advanced stages, which can result in fewer options for effective and accessible treatments. While diagnostic testing plays an important role in determining next steps, many of these procedures are invasive and may be associated with additional health risks.
The Global Burden of Disease and Health Risk
544.9 million people
suffer worldwide from chronic respiratory diseases 1
3-10% of women
in the world experience
preeclampsia during
pregnancy 2
10% of the population
worldwide is affected by
chronic kidney disease 3
Turning Signatures into Powerful Insights
A single blood sample offers a world of insights into a person’s health. That’s why our research platform utilizes cell free DNA (cfDNA) obtained from a noninvasive liquid biopsy. Through our innovative lab techniques and patented analytical approaches, we can identify relevant data, or “signatures”, and use them to determine early health indicators.
Our Research Areas
Women's Reproductive Health
We are dedicated to advancing noninvasive diagnostics to create better health outcomes for women. With growing concerns in the maternal health space, our research focuses on developing novel solutions to safely predict and detect pregnancy-related complications as well as conditions affecting women's overall reproductive health.
Women's Reproductive Health
We are dedicated to advancing noninvasive diagnostics to create better health outcomes for women. With growing concerns in the maternal health space, our research focuses on developing novel solutions to safely predict and detect pregnancy-related complications.
Organ Health
Our research includes the study of organs, organ systems, and the unique complications associated with organ transplants. Through our approach of noninvasive liquid biopsy, we are developing diagnostic tools that can monitor the long-term health of kidneys and lungs and detect early indications of organ transplant rejection.
References
- GBD Chronic Respiratory Disease Collaborators (2020). Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet. Respiratory medicine, 8(6), 585–596. https://doi.org/10.1016/S2213-2600(20)30105-3
- Hansson, T., Andersson, M. E., Ahlström, G., & Hansson, S. R. (2022). Women´s experiences of preeclampsia as a condition of uncertainty: a qualitative study. BMC pregnancy and childbirth, 22(1), 521. https://doi.org/10.1186/s12884-022-04826-5
- Kidney Disease: Improving Global Outcomes (KDIGO) Lupus Nephritis Work Group. (January 2024). KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney International, 105(1), S1-S197. https://doi.org/10.1016/j.kint.2023.09.002