Agentic AI systems are evolving from tool‑driven workflows into autonomous agents that can perceive, react, and operate in dynamic environments. This talk uses OpenClaw as a reference architecture to explore how agentic systems can move beyond single‑machine orchestration toward perception‑aware, production‑ready deployments.
We begin with OpenClaw’s core design—gateway‑based orchestration, tool execution, and local‑first workflows—and examine its limitations when scaling toward real‑time, autonomous behavior. From there, we introduce architectural patterns for integrating perception signals and environment feedback, enabling agents to reason and act in continuously changing contexts.
The session then covers key system challenges, including state management, observability, and coordination, along with practical approaches for scaling these systems across distributed environments. We conclude with concrete architectural principles for building robust, perception‑aware agentic systems that combine infrastructure rigor, extensible toolchains, and real‑world responsiveness.
2026 John C. Martin Memorial Lectureship
LectureHonor the legacy of the renowned scientist, visionary businessman and global health pioneer, John C. Martin, at this annual event.
Join us for the fifth annual John C. Martin Memorial Lectureship at Scripps Research.
This event honors the legacy of renowned scientist, visionary leader, and global health champion John C. Martin. Each year, we come together to spotlight scientific breakthroughs and foster collaboration between academia and industry—all in the pursuit of improving human health. This year’s agenda includes:
1:00 p.m. – Welcome by Pete Schultz, PhD, President and CEO, Scripps Research
1:10 p.m. – Keynote presentation by Nicholas Leeper, PhD, Professor of Vascular Surgery and Chief of Vascular Medicine, Stanford University
2:30 p.m. – Keynote presentation by Stuart Schreiber, PhD, Founding Core Institute Member Emeritus, Broad Institute of MIT and Harvard
3:30 p.m. – Closing remarks by Gregg Alton, JD, Former Chief Patient Officer, Gilead
3:45 p.m. – Reception in the Hazen courtyard
Registration is required to join us for this event in person. Please confirm your attendance prior to April 8, 2026.
For any event-related questions, please contact us at [email protected].
Startup Quarters Curated Conversations
Community BuildingStartup Quarters is a weekly gathering held every Wednesday, discussing in breakout groups, Curated Conversations where founders and builders share ideas and work through challenges in real time. Designed to create momentum through consistent connection, it brings together multiple startup-focused interactions in one place, fostering ongoing mentorship, collaboration, and meaningful conversations that build week over week.
Designing Water Resilient Buildings
WebinarLearn how onsite water recycling systems reduce potable demand, support LEED v5, and drive resilient, water-positive building design.
Designing Water Resilient Buildings: Onsite Water Recycling Solutions for the Built Environment
As water scarcity, infrastructure strain, population growth, and conservation mandates intensify, design teams are being asked to rethink how buildings source, use, and reuse water. This continuing education webinar introduces onsite water recycling solutions as a practical, proven strategy to reduce potable water demand, support resilient design, meet regulatory requirements, and achieve long-term performance goals.
The course provides a practical overview of onsite wastewater reuse systems (OWRS), including greywater and blackwater treatment approaches. Participants will explore system components, treatment processes, and spatial planning considerations, with an emphasis on early design coordination and real-world constructability.
Through case studies and code-informed guidance, attendees will learn how closed-loop water systems can support LEED v5, reduce operational costs, and advance water-positive building strategies. Regulatory pathways, permitting considerations, incentives, and public health safeguards will also be addressed.
By the end of the session, participants will be equipped to evaluate when onsite water recycling is appropriate, how it impacts building design, and how to specify systems that maximize reuse while minimizing reliance on potable water supplies.
Learning Objectives
Participants will be able to:
This course is sponsored by: Epic Cleantec
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Please be aware that USGBC-CA may capture photos and videos during this event. By participating, you may appear in these visual recordings. Your presence at the event signifies your consent to be featured in these photos or videos, which may be utilized for educational, archival, or promotional endeavors.
Foundations of Green Building
WebinarJoin us to learn about the foundations of green building design, materials, and jobs. Earn 4 GBCI credits & a certificate after a quiz.
Join us for a virtual webinar to learn about the foundations of green building design, materials, and jobs. Earn 4 GBCI credits and a certificate after a 25-question exam.
Buildings wield significant influence over our environment, neighboring communities, and the individuals who inhabit them. Recognizing and mitigating these impacts through building modernization is crucial. In this course, you will delve into the intricacies of green, high-performing buildings, exploring elements such as building design, operational strategies, project location, and materials selection. You’ll also gain insights into the expanding realm of green jobs, a vital component of this sustainable transition. Upon successful completion of a 25-question exam following the class, attendees will receive a certificate of completion.
LEARNING OBJECTIVES:
This course is sponsored by: San Diego Learn
Cross Platform Apps with React Native
Business & Professionals, Entrepreneurs, Investors & Funding, NetworkingWhen you need an app that can work on iOS and Android, React Native lets you write code that will work across both platforms.
In this meetup we’ll have a presentation from our member, Ross, where he’ll talk about his experience using React Native.
When is worth using? and how has AI changed the workflow?
For regular attendees please note it starts at 6:30 now instead of 6:15.
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It will take place in the Seminar Room at the La Jolla Riford Libary which has a capacity of 40 people. The meeting is usually around an hour, but will go no more than 90 minutes since the library closes. There is parking lot at the library and parking on the street in the surrounding area.
Everyone interested is welcome: app developers, business owners, entrepreneurs, and investors. The idea is to grow this group to be a great networking hub where people can meet each other for projects and/or friendships.
Discover The Science and The Magic Behind Living Light
Biotech & Life Sciences📅 Tuesday, April 14th, 2026
⏰ Talk at 7:30 PM (Doors at 6:00 PM)
📍 University Club – San Diego
🧠 Featuring Dimitri Deheyn, a marine biologist at Scripps Institution of Oceanography at UC San Diego, focused on bioluminescence, biofluorescence, and marine ecotoxicology. His work examines how marine organisms generate and alter light signals as he observes, quantifies, and tests these changes to detect stress and contaminants, supporting ocean health, environmental monitoring, and conservation.
OpenClaw Architecture: From Tool‑Orchestrated Agents to Perception‑Aware Autonomous Systems
AI, VirtualAgentic AI systems are evolving from tool‑driven workflows into autonomous agents that can perceive, react, and operate in dynamic environments. This talk uses OpenClaw as a reference architecture to explore how agentic systems can move beyond single‑machine orchestration toward perception‑aware, production‑ready deployments.
We begin with OpenClaw’s core design—gateway‑based orchestration, tool execution, and local‑first workflows—and examine its limitations when scaling toward real‑time, autonomous behavior. From there, we introduce architectural patterns for integrating perception signals and environment feedback, enabling agents to reason and act in continuously changing contexts.
The session then covers key system challenges, including state management, observability, and coordination, along with practical approaches for scaling these systems across distributed environments. We conclude with concrete architectural principles for building robust, perception‑aware agentic systems that combine infrastructure rigor, extensible toolchains, and real‑world responsiveness.
Investor Readiness: Funding Fundamentals Exploring Diverse Capital Pathways
Startups & Founders, WorkshopUnderstanding funding basics and exploring multiple capital options to prepare businesses for successful investment readiness.
The Brink SBDC at University of San Diego, Knauss School of Business presents Investor Readiness: Funding Fundamentals Exploring Diverse Captial Pathways.
In this Investor Readiness workshop, founders will gain a clear understanding of the full spectrum of capital options available to early-stage companies—and how to choose the right path at the right time. Led by Silvia Mah, a seasoned angel investor, venture advisor, and professor of entrepreneurship, this session helps founders move beyond a “VC-only” mindset toward more strategic, values-aligned funding decisions.
Hosted at The Brink SBDC, the workshop breaks down equity and non-dilutive capital options, investor expectations, and trade-offs founders must consider before raising. Founders will learn how different capital pathways impact ownership, governance, growth pace, and long-term outcomes—so they can fundraise with intention, not pressure.
What You’ll Learn:
ISACA San Diego April Meeting
Cybersecurity, Discussions, HybridWhat A Career in Cybersecurity Taught Me That Certifications Didn’t
Where I started in IT and how that career path eventually led me into cybersecurity. I will briefly cover some of the various IT roles I filled along the way and what really helped me and what didn’t.
We will also discuss some of the non-technical lessons learned that had a big impact on how I approached cyber and the team building process once I was in upper management roles. Hoping for an interactive session as we discuss in a very honest way what being in cybersecurity is really like.
SPEAKER: Gary Martino, CEO at Sicura Networks LLC
Gary has over 20 years of cyber security experience implementing compensating controls and identifying and quantifying risks to comply with PCI, ISO, NIST, and HIPAA regulations. Working across various industries including defense, healthcare, hospitality, sport and leisure to build successful security teams to detect and protect against the latest threats.
Over the years, Gary has held various industry certifications in both IT and Security and is currently enjoying retirement and spending much needed time with family.
Visit Gary on LinkedIn: https://www.linkedin.com/in/gary-martino-8487567/
DETAILS:
Date: Thursday, April 16
Time: 12:00 – 1:15 p.m.
Location: In-Person and Online via Zoom
CPE: 1
Fine Tuning Large Language Models (LLMs) with Domain Specific Datasets
Computer Science, Virtual, WebinarLarge language models (LLMs) are trained on massive, publicly available text datasets comprising trillions of tokens, enabling them to excel at general language tasks like next-token prediction. However, LLMs often struggle with domain-specific prompts, exhibiting reduced accuracy or generating inaccurate information (hallucinations). This is because they lack sufficient subject matter expertise. Two primary approaches exist to address this limitation for augmenting LLMs knowledge: Retrieval-Augmented Generation (RAG) and fine-tuning. This presentation focuses on fine-tuning smaller LLMs with domain-specific instruct datasets using the LoRA (Low-Rank Adaptation) technique on Gaudi hardware. We will leverage publicly available LLMs and datasets from the Hugging Face Hub for this demonstration. Though it is possible to fine tune LLMs with plain text data – sourced from documents, articles, and other materials.