Hospital Militar Central

Aim: To assess whether levothyroxine treatment improves functional capacity in patients with chronic heart failure (New York Heart Association class I---III) and subclinical hypothyroidism. Methods: One hundred and sixty-three outpatients with stable chronic heart failure followed up for at least 6 months were enrolled. A physical examination was performed, and laboratory tests including thyroid hormone levels, Doppler echocardiogram, radionuclide ventriculography, and Holter monitoring were requested. Functional capacity was assessed by of the 6-min walk test. Patients with subclinical hypothyroidism were detected and, after undergoing the s6-min walk test, were given replacement therapy. When they reached normal thyrotropin (TSH) levels, the 6-min walk test was performed again. The distance walked in both tests was recorded, and the difference in meters covered by each patient was analyzed. Results: Prevalence of subclinical hypothyroidism in patients with heart failure was 13%. These patients walked 292 ± 63 m while they were hypothyroid and 350 ± 76 m when TSH levels returned to normal, a difference of 58 ± 11 m (P < .011). Patients with normal baseline TSH levels showed no significant difference between the two 6-min walk tests. Conclusions: Patients with chronic heart failure and subclinical hypothyroidism significantly improved their physical performance when normal TSH levels were reached.

Relación del síndrome metabólico y sus componentes con la presión del pulso en personas sin enfermedad aparente Revista Argentina de Cardiología, vol. 78, núm. 3, mayo-junio, 2010, pp. 215-221 Sociedad Argentina de Cardiología Buenos Aires, Argentina Disponible en: http://www.redalyc.org/articulo.oa?id=305326921011 Cómo citar el artículo Número completo Más información del artículo Página de la revista en redalyc.org Sistema de Información Científica Red de Revistas Científicas de América Latina, el Caribe, España y Portugal Proyecto académico sin fines de lucro, desarrollado bajo la iniciativa de acceso abierto SÍNDROME METABÓLICO Y PRESIÓN DEL PULSO / Antonio J. Paragano y col.