Papers by M.Saifur Rahman
In this paper, we propose a rigorous configuration of graphene coated surface plasmon resonance (... more In this paper, we propose a rigorous configuration of graphene coated surface plasmon resonance (SPR) sensor with Tungsten Disulfide (WS2) for sensing DNA hybridization. The present configuration is consisted of prism (SF10 glass), Gold (Au), WS2- graphene and sensing medium. We perform the performance parameters of the proposed sensor in terms of sensitivity, detection accuracy and quality factor. Here we report a dramatic enhancement of the overall performance. Addition of graphene layers increase the sensitivity but decrease the other performance parameters. To increase the all performance parameters we add WS2 between metal and graphene layer. Furthermore in this paper, the thickness effect of Gold (Au) is also analyzed. Numerical analysis shows that the variation of SPR angle for mismatched DNA strands is quiet negligible whereas that for complementary DNA strands is considerably countable. Therefore, the proposed biosensor opens a new window towards detection for biomolecular interactions.
American Scientific Publishers, 2017
Planar waveguide surface plasmon resonance sensors have great potential for use in the field of
b... more Planar waveguide surface plasmon resonance sensors have great potential for use in the field of
biosensing research. In this paper, we investigated a new surface plasmon resonance (SPR) based
optical waveguide sensor for sensing DNA hybridization. Performance of the proposed sensor is
analyzed in terms of sensitivity, detection accuracy and quality factor. By the addition of graphene
layers with the conventional SPR, sensitivity is increased but detection accuracy and quality factor is
decreased. Hence to increase the overall performance including detection accuracy and quality factor, MoS
2-graphene hybrid structure is used in the middle of metal and sensing layer. The improved
sensing property by proposed SPR structure combinedwith the absorption ability and optical characteristics of graphene biomolecules and high fluorescence quenching ability of MoS2
. Numerical
investigation also reflects the variation of resonance angle and spectrum of transmitted power for
mismatched DNA strands and for complementary DNA strands. These variations are negligible for
mismatched DNA strands whereas significantly computable for complementary DNA strands. Proposed sensor successfully differentiates hybridization and single nucleotide polymorphisms (SNP)
by observing the variation level of resonance angle and spectrum of transmitted power.
This paper presents a highly sensitive photonic crystal fiber (PCF) refractive index sensor based... more This paper presents a highly sensitive photonic crystal fiber (PCF) refractive index sensor based on
the surface plasmon resonance (SPR) effect operating in the telecommunication wavelengths. Gold is used as
the plasmonic material due to its chemical stability and titanium dioxide (TiO2) is used to shift the resonance
wavelength in the telecommunication bands. Both materials are deposited sequentially on the PCF surface,
which is comparatively easy to fabricate. Numerical investigations show that the proposed sensor exhibits
very high wavelength sensitivity of 10;800 nm∕RIU and amplitude sensitivity of 514 RIU−1 in the sensing
range between 1.46 and 1.48. Moreover, it exhibits maximum sensor resolution of 9.25 × 10−6 RIU and high
linearity over a wide sensing range. The proposed sensor can be practically realized due to its simple and
straightforward structure.
Planar waveguide based surface plasmon resonance (SPR) biosensor is proposed and numerically inve... more Planar waveguide based surface plasmon resonance (SPR) biosensor is proposed and numerically investigated for the detection of DNA hybridization. Thorough numerical analysis reveals that the proposed graphene coated on gold SPR biosensor shows 1 + 045L (where L is the number of graphene layers) times better sensitivity than that of obtained in conventional SPR biosensor. Sensitivity of the designed biosensor is enhanced by using superior optical characteristics of graphene. Hybridization with mismatched and complementary targets DNA is thoroughly discussed with different probe and complementary target molecules. Numerical analysis reflects the variation of resonance angle and spectrum of the transmitted power for both mismatched DNA and complementary DNA strands. These variations are negligible for mismatched DNA strands whereas significantly computable for complementary DNA strands. The proposed sensor effectively differentiates between hybridization and single nucleotide polymorphisms (SNP) by examining the level of changes in resonance angle. Due to straightforward structural design, the proposed planar waveguide based biosensor can be implemented in numerous real time sensing applications.
This paper demonstrates a promising surface plasmon resonance (SPR) biosensor for the sensing of ... more This paper demonstrates a promising surface plasmon resonance (SPR) biosensor for the sensing of DNA hybridization. We measure the performance parameters of the proposed sensor in terms of sensitivity, detection accuracy and quality factor using air gap as the dielectric medium. It carries the amenities of the absorption ability and optical characteristics of graphene, high fluores-cence quenching ability of MoS 2 and sharp reflectance curve of silver. Thorough numerical analysis shows that proposed biosensor exhibits high angular sensitivity of 80.71 degree/RIU with reasonable detection accuracy and quality factor of 1.628 and 23.40 RIU −1 , respectively. The proposed biosensor successfully differentiates the hybridization observing the variation of resonance angle and reflectance; therefore, it can be potentially used for the detection of DNA hybridization.
Optical fiber instead of prism is now widely studied in biosensing research. This paper investiga... more Optical fiber instead of prism is now widely studied in biosensing research. This paper investigates a
highly sensitive optical fiber based Ag-MoS2-Graphene hybrid surface plasmon resonance (SPR) biosensor for
sensing DNA hybridization. Sensitivity, detection accuracy and quality factor are carefully studied for the
performance analysis. Numerical study shows that usingsingle layer of MoS2 in the middle of a Graphene-on-Ag
layer, the fiber optic biosensor exhibits high sensitivity of 105.71 deg/RIU with reasonable detection accuracy
and quality factor of 1.626 and 23.23 RIU
-1
, respectively. This enhanced sensitivity is due to the absorption ability
and optical characteristics of graphene biomolecules and high fluorescence quenching ability of MoS2. Numerical
investigation also reflects the variation of resonance angle and spectrum of transmitted power for mismatched
DNA strands and for complementary DNA strands. These variations are negligible for mismatched DNA strands
whereas significantly computable for complementary DNA strands. Thus the proposed sensor effectively
differentiates hybridization and single nucleotide polymorphisms (SNP) by examining the level of changes in
resonance angle and transmitted power spectrum. Therefore, this fiber optic based Ag-MoS2-Graphene hybrid
biosensor might be a promising candidate for the detection of DNA hybridization
—In this paper a theoretical porous silicon surface based plasmon resonance (SPR) sensor has been... more —In this paper a theoretical porous silicon surface based plasmon resonance (SPR) sensor has been presented consisting graphene-Melybdenum sulphide (MoS2) hybrid structure for enhancing sensor detection sensitivity. The biosensor uses perfectly matched layer (PML) boundary condition incorporating on its computational domain to improve its surface plasmon resonance characteristics. Here, graphene-MoS2 hybrid sheet is used to detect the refractive index change of the sensor surface, which is cause of the reaction of biomolecules. Our calculations show that the graphene-MoS2 hybrid structure on silicon porous sensor has 25% more sensitivity than the conventional silicon resonant sensor. The enhanced sensitivity is for increasing SPR angle about 25% by adding graphene-MoS2 hybrid structure.
A B S T R A C T We demonstrate a highly sensitive Au-MoS 2-Graphene based hybrid surface plasmon ... more A B S T R A C T We demonstrate a highly sensitive Au-MoS 2-Graphene based hybrid surface plasmon resonance (SPR) biosensor for the detection of DNA hybridization. The performance parameters of the proposed sensor are investigated in terms of sensitivity, detection accuracy and quality factor at operating wavelength of 633 nm. We observed in the numerical study that sensitivity can be greatly increased by adding MoS 2 layer in the middle of a Graphene-on-Au layer. It is shown that by using single layer of MoS 2 in between gold and graphene layer, the proposed biosensor exhibits simultaneously high sensitivity of 87.8 deg/RIU, high detection accuracy of 1.28 and quality factor of 17.56 with gold layer thickness of 50 nm. This increased performance is due to the absorption ability and optical characteristics of graphene biomolecules and high fluorescence quenching ability of MoS 2. On the basis of changing in SPR angle and minimum reflectance, the proposed sensor can sense nucleotides bonding happened between double-stranded DNA (dsDNA) helix structures. Therefore, this sensor can successfully detect the hybridization of target DNAs to the probe DNAs pre-immobilized on the Au-MoS 2-Graphene hybrid with capability of distinguishing single-base mismatch.
This paper proposes an effective model for prediction of different blood diseases by measuring th... more This paper proposes an effective model for prediction of different blood diseases by measuring the electromagnetic field created by human heart using SQUID meter. Four parameters such as voltage, current, resistivity of blood and accumulation time are measured using the proposed model and hence developed a relationship to find out various types of diseases such as diabetes, polycythemia, and anemia. Resistivity of blood is used as disease determinant that plays a vital role for prediction the disease. A number of experiments have been done to ascertain the accumulation time of blood particles from a patient blood which gives staggering information.
This paper proposes, designs and constructs an image recognition & voice technology based securit... more This paper proposes, designs and constructs an image recognition & voice technology based security system by highlighting the advantages of image processing technology and voice synthesis technology which are presence in the electronic market. This paper mainly approaches towards enhanced security by checking the tag image of the operator as well as recognizing voice which are validated previously by this system just using simply a web-camera or closed circuit television (CCTV) camera and a voice recording software system and gives the signal in terms of alarm, Alert Light, message via global system for mobile communication (GSM)/ general packet radio service (GPRS) to the consumer mobile number/the nearest police station's mobile number.
Thesis Chapters by M.Saifur Rahman
Surface plasmon resonance biosensors are introduced that transact to report specially the detecti... more Surface plasmon resonance biosensors are introduced that transact to report specially the detection of DNA Hybridization. The detection technique is attenuated total reflection (ATR) method, which is happened due to the adsorption of biomolecules and refractive index change near the sensor surface. This proposed sensors sensed nucleotides bonding happened between double-stranded (dsDNA) helix structure, based on the change of surface plasmon resonance (SPR) angle-the change of minimum reflectance (Rmin) attributor and the surface plasmon resonance (SPR) angle- maximum transmittance (Tmax) attributor. Numerical analysis shows that the variation of SPR angle for mismatched DNA strands is quiet negligible whereas that for complementary DNA strands is considerably countable. Here, sensors are designed based on graphene, graphene –MoS2 hybrid structure material as bimolecular recognition elements (BRE) and the sharp SPR curve of silver (Ag) and gold (Au). These materials are implemented to perform faster immobilization between target DNA and probe DNA. Proposed sensors can efficiently identify the hybridization of target DNAs to the probe DNAs pre-immobilized on graphene with capability to distinguish single-base mismatch. In additionally the methodology of this study is presented for diagnosis of the single-nucleotide polymorphisms (SNP) which uses a graphene coated DNA sensor.Numerical calculations reveal that the proposed graphene coated on gold SPR waveguide biosensor has 1 + 0.4 L; (where L is the number of graphene sub-layers) times more sensitivity than the conventional SPR biosensor when SPR angle-Tmin attributor is used as detecting parameters. The prolonged sensitivity is due to enhanced SPR angle change about 40L% by adding graphene layer and using the optical property of graphene. On the other hand using single layer of MoS2 in between gold and graphene layer, the proposed biosensor exhibits simultaneously high sensitivity of 87.8 deg/ RIU, high detection accuracy of 1.28 and quality factor of 17.56 with gold layer thickness of 50 nm in case of prism based SPR biosensor. This increased performance is due to the absorption ability and optical characteristics of graphene biomolecules and high fluorescence quenching ability of Mo¬¬S¬2.In addition, performance of the MoS2-graphne hybrid structure based prism biosensor is analyzed using air gap. Further for the case of fiber optic SPR biosensor using single layer of MoS2 in the middle of a Graphene-on-Ag layer, the fiber optic biosensor exhibits high sensitivity of 105.71 deg/RIU with reasonable detection accuracy and quality factor of 1.626 and 23.23 RIU1,respectively.
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Papers by M.Saifur Rahman
biosensing research. In this paper, we investigated a new surface plasmon resonance (SPR) based
optical waveguide sensor for sensing DNA hybridization. Performance of the proposed sensor is
analyzed in terms of sensitivity, detection accuracy and quality factor. By the addition of graphene
layers with the conventional SPR, sensitivity is increased but detection accuracy and quality factor is
decreased. Hence to increase the overall performance including detection accuracy and quality factor, MoS
2-graphene hybrid structure is used in the middle of metal and sensing layer. The improved
sensing property by proposed SPR structure combinedwith the absorption ability and optical characteristics of graphene biomolecules and high fluorescence quenching ability of MoS2
. Numerical
investigation also reflects the variation of resonance angle and spectrum of transmitted power for
mismatched DNA strands and for complementary DNA strands. These variations are negligible for
mismatched DNA strands whereas significantly computable for complementary DNA strands. Proposed sensor successfully differentiates hybridization and single nucleotide polymorphisms (SNP)
by observing the variation level of resonance angle and spectrum of transmitted power.
the surface plasmon resonance (SPR) effect operating in the telecommunication wavelengths. Gold is used as
the plasmonic material due to its chemical stability and titanium dioxide (TiO2) is used to shift the resonance
wavelength in the telecommunication bands. Both materials are deposited sequentially on the PCF surface,
which is comparatively easy to fabricate. Numerical investigations show that the proposed sensor exhibits
very high wavelength sensitivity of 10;800 nm∕RIU and amplitude sensitivity of 514 RIU−1 in the sensing
range between 1.46 and 1.48. Moreover, it exhibits maximum sensor resolution of 9.25 × 10−6 RIU and high
linearity over a wide sensing range. The proposed sensor can be practically realized due to its simple and
straightforward structure.
highly sensitive optical fiber based Ag-MoS2-Graphene hybrid surface plasmon resonance (SPR) biosensor for
sensing DNA hybridization. Sensitivity, detection accuracy and quality factor are carefully studied for the
performance analysis. Numerical study shows that usingsingle layer of MoS2 in the middle of a Graphene-on-Ag
layer, the fiber optic biosensor exhibits high sensitivity of 105.71 deg/RIU with reasonable detection accuracy
and quality factor of 1.626 and 23.23 RIU
-1
, respectively. This enhanced sensitivity is due to the absorption ability
and optical characteristics of graphene biomolecules and high fluorescence quenching ability of MoS2. Numerical
investigation also reflects the variation of resonance angle and spectrum of transmitted power for mismatched
DNA strands and for complementary DNA strands. These variations are negligible for mismatched DNA strands
whereas significantly computable for complementary DNA strands. Thus the proposed sensor effectively
differentiates hybridization and single nucleotide polymorphisms (SNP) by examining the level of changes in
resonance angle and transmitted power spectrum. Therefore, this fiber optic based Ag-MoS2-Graphene hybrid
biosensor might be a promising candidate for the detection of DNA hybridization
Thesis Chapters by M.Saifur Rahman
biosensing research. In this paper, we investigated a new surface plasmon resonance (SPR) based
optical waveguide sensor for sensing DNA hybridization. Performance of the proposed sensor is
analyzed in terms of sensitivity, detection accuracy and quality factor. By the addition of graphene
layers with the conventional SPR, sensitivity is increased but detection accuracy and quality factor is
decreased. Hence to increase the overall performance including detection accuracy and quality factor, MoS
2-graphene hybrid structure is used in the middle of metal and sensing layer. The improved
sensing property by proposed SPR structure combinedwith the absorption ability and optical characteristics of graphene biomolecules and high fluorescence quenching ability of MoS2
. Numerical
investigation also reflects the variation of resonance angle and spectrum of transmitted power for
mismatched DNA strands and for complementary DNA strands. These variations are negligible for
mismatched DNA strands whereas significantly computable for complementary DNA strands. Proposed sensor successfully differentiates hybridization and single nucleotide polymorphisms (SNP)
by observing the variation level of resonance angle and spectrum of transmitted power.
the surface plasmon resonance (SPR) effect operating in the telecommunication wavelengths. Gold is used as
the plasmonic material due to its chemical stability and titanium dioxide (TiO2) is used to shift the resonance
wavelength in the telecommunication bands. Both materials are deposited sequentially on the PCF surface,
which is comparatively easy to fabricate. Numerical investigations show that the proposed sensor exhibits
very high wavelength sensitivity of 10;800 nm∕RIU and amplitude sensitivity of 514 RIU−1 in the sensing
range between 1.46 and 1.48. Moreover, it exhibits maximum sensor resolution of 9.25 × 10−6 RIU and high
linearity over a wide sensing range. The proposed sensor can be practically realized due to its simple and
straightforward structure.
highly sensitive optical fiber based Ag-MoS2-Graphene hybrid surface plasmon resonance (SPR) biosensor for
sensing DNA hybridization. Sensitivity, detection accuracy and quality factor are carefully studied for the
performance analysis. Numerical study shows that usingsingle layer of MoS2 in the middle of a Graphene-on-Ag
layer, the fiber optic biosensor exhibits high sensitivity of 105.71 deg/RIU with reasonable detection accuracy
and quality factor of 1.626 and 23.23 RIU
-1
, respectively. This enhanced sensitivity is due to the absorption ability
and optical characteristics of graphene biomolecules and high fluorescence quenching ability of MoS2. Numerical
investigation also reflects the variation of resonance angle and spectrum of transmitted power for mismatched
DNA strands and for complementary DNA strands. These variations are negligible for mismatched DNA strands
whereas significantly computable for complementary DNA strands. Thus the proposed sensor effectively
differentiates hybridization and single nucleotide polymorphisms (SNP) by examining the level of changes in
resonance angle and transmitted power spectrum. Therefore, this fiber optic based Ag-MoS2-Graphene hybrid
biosensor might be a promising candidate for the detection of DNA hybridization