OnCore
OnCore
OnCore is the University’s clinical research management system, supporting end-to-end oversight of studies conducted at UNC. It provides comprehensive functionality across protocol, calendar, and subject management; centralized and standardized coverage analysis, invoicing, and financial reconciliation; and robust reporting and analytics tools that strengthen operational efficiency, compliance, and data quality. Integration with other research systems such as IRBIS and Epic help streamline study and subject documentation across systems.
Review the Managing Clinical Research Administrative Data Policy and Standard to learn more about OnCore requirements.
OnCore News & Updates
June 1, 2026: Institutional Approval Now Live
The Institutional Approval process is now live. This process applies to all studies initiated on or after June 1, 2026. Researchers may notice a new protocol status of “Institutional Approval Signoff” before opening their study to accrual as well as the addition of new task lists. For questions regarding the Institutional Approval process or issues opening a study to accrual, please contact [email protected]. For all other inquiries, please continue to submit an OnCore Support ticket via TDX as usual.
Subscribe to OnCore Announcements to receive updates on upcoming maintenance, upgrades, features, and OnCore news.
OnCore Features
OnCore utilization for study management allows researchers to:
Improve and streamline research enrollment and tracking
Standardize processes and workflows
Improve billing compliance through integrated billing coverage analyses and qualifying clinical trial checklists
Centralize sponsor invoicing and manage revenue reconciliation
Provide quality metrics on study development, accruals, costs, resources, and impact of clinical trials to research leaders
OnCore Training
Training is required before receiving OnCore access. Users should complete role-based training(s) that match their job responsibilities. Training is provided via Zoom or asynchronously via Carolina Talent.
An Access Request Form must be completed in TDX before training is assigned.
OnCore Guides
Detailed tip sheets and guidance videos can be found on the UNC Research OnCore Support and Resources page.
Questions and Support
For OnCore questions, support, and feedback, please submit a request through the OnCore Support Portal.