This paper is dedicated to the memory of our ATLAS colleagues who did not live to see the full im... more This paper is dedicated to the memory of our ATLAS colleagues who did not live to see the full impact and significance of their contributions to the experiment.
Proceedings of The National Academy of Sciences, 2001
Open reading frame expressed sequences tags (ORESTES) differ from conventional ESTs by providing ... more Open reading frame expressed sequences tags (ORESTES) differ from conventional ESTs by providing sequence data from the central protein coding portion of transcripts. We generated a total of 696,745 ORESTES sequences from 24 human tissues and used a subset of the data that correspond to a set of 15,095 full-length mRNAs as a means of assessing the efficiency of the strategy and its potential contribution to the definition of the human transcriptome. We estimate that ORESTES sampled over 80% of all highly and moderately expressed, and between 40% and 50% of rarely expressed, human genes. In our most thoroughly sequenced tissue, the breast, the 130,000 ORESTES generated are derived from transcripts from an estimated 70% of all genes expressed in that tissue, with an equally efficient representation of both highly and poorly expressed genes. In this respect, we find that the capacity of the ORESTES strategy both for gene discovery and shotgun transcript sequence generation significantly exceeds that of conventional ESTs. The distribution of ORESTES is such that many human transcripts are now represented by a scaffold of partial sequences distributed along the length of each gene product. The experimental joining of the scaffold components, by reverse transcription-PCR, represents a direct route to transcript finishing that may represent a useful alternative to full-length cDNA cloning.
A search for diphoton events with large missing transverse energy is presented. The data were col... more A search for diphoton events with large missing transverse energy is presented. The data were collected with the ATLAS detector in proton-proton collisions at √ s = 7 TeV at the CERN Large
A search for the electroweak pair production of charged sleptons and weak gauginos decaying into ... more A search for the electroweak pair production of charged sleptons and weak gauginos decaying into final states with two leptons is performed using 4.7 fb −1 of proton-proton collision data at √ s = 7 TeV recorded with the ATLAS experiment at the Large Hadron Collider. No significant excesses are observed with respect to the prediction from Standard Model processes. In the scenario of direct slepton production, if the sleptons decay directly into the lightest neutralino, left-handed slepton masses between 85 and 195 GeV are excluded at 95% confidence level for a 20 GeV neutralino. Chargino masses between 110 and 340 GeV are excluded in the scenario of direct production of wino-like chargino pairs decaying into the lightest neutralino via an intermediate on-shell charged slepton for a 10 GeV neutralino. The results are also interpreted in the framework of the phenomenological minimal supersymmetric Standard Model.
This paper describes the measurement of elliptic flow of charged particles in lead-lead collision... more This paper describes the measurement of elliptic flow of charged particles in lead-lead collisions at √ s NN = 2.76 TeV using the ATLAS detector at the Large Hadron Collider (LHC). The results are based on an integrated luminosity of approximately 7 µb −1 . Elliptic flow is measured over a wide region in pseudorapidity, |η| < 2.5, and over a broad range in transverse momentum, 0.5 < p T < 20 GeV. The elliptic flow parameter v 2 is obtained by correlating individual tracks with the event plane measured using energy deposited in the forward calorimeters. As a function of transverse momentum, v 2 (p T ) reaches a maximum at p T of about 3 GeV, then decreases and becomes weakly dependent on p T above 7-8 GeV. Over the measured pseudorapidity region, v 2 is found to be only weakly dependent on η, with less variation than observed at lower beam energies. The results are discussed in the context of previous measurements at lower collision energies, as well as recent results from the LHC.
The present article reviews the literature about the main contributions of fathers and siblings t... more The present article reviews the literature about the main contributions of fathers and siblings to the disabled individual development based on the family systems perspective. The purpose is to deepen the subject families of disabled people, focusing those elements that have been left in a second plan in studies of this area, father and siblings, showing their importance in the development of these individuals. Thus, aspects of the relation fatherindividual with special needs and siblingsindividual with special needs in literature are argued, elucidating the practical and methodological challenges of these studies that investigate such relations. One expects to contribute, in this analysis, for the interest increase in the related area.
Measurement of the centrality dependence of the charged particle pseudorapidity distribution in l... more Measurement of the centrality dependence of the charged particle pseudorapidity distribution in lead-lead collisions at √ s NN = 2.76 TeV with the ATLAS detector
Post-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the f... more Post-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the fact that there are many reports about the association of visceral leishmaniasis and AIDS, PKDL is very uncommon in HIV-positive patients, and so far only four cases have been documented in the literature. We present another case with unusual clinicopathological aspects. The patient, a 28-year-old male, from Salvador, Bahia (an endemic area) presented with clinical manifestations of visceral leishmaniasis three years after the diagnosis of AIDS. During treatment for visceral leishmaniasis he developed disseminated miliary papules. Microscopically, the skin biopsy showed a &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;saw-tooth&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot; pattern with a lichenoid mononuclear infiltrate simulating lichen planus. The histopathological diagnosis was achieved through the finding of amastigotes. The authors discuss the clinicopathological aspects of this case based on a review of the specific literature.
A comparative study between crotoxin and gamma irradiated crotoxin was performed on the indirectl... more A comparative study between crotoxin and gamma irradiated crotoxin was performed on the indirectly evoked twitches and tetani of sciatic nerve-extensor digitorum longus muscle of rats. Crotoxin (3 to 14 microg/ml) decreased the amplitude of twitches and induced a slight tetanic fade, and irradiated crotoxin did not significantly affect either twitch amplitude or tetanic tension. Since gamma radiation reduced the neurotoxicity of crotoxin it may be useful for the production of anticrotalic serum.
A search for production of supersymmetric particles in final states containing jets, missing tran... more A search for production of supersymmetric particles in final states containing jets, missing transverse momentum, and at least one hadronically decaying τ lepton is presented. The data were recorded by the ATLAS experiment in √ s = 7 TeV proton-proton collisions at the Large Hadron Collider. No excess above the Standard Model background expectation was observed in 2.05 fb −1 of data. The results are interpreted in the context of gauge mediated supersymmetry breaking models with M mess = 250 TeV, N 5 = 3, µ > 0, and C grav = 1. The production of supersymmetric particles is excluded at 95% C.L. up to a supersymmetry breaking scale Λ = 30 TeV, independent of tan β, and up to Λ = 43 TeV for large tan β.
Jaids-journal of Acquired Immune Deficiency Syndromes, 2008
Context-Since drug-involved women are among the fastest growing groups with AIDS, sexual risk red... more Context-Since drug-involved women are among the fastest growing groups with AIDS, sexual risk reduction intervention for them is a public health imperative.
Measurements are presented from proton-proton collisions at centre-of-mass energies of √ s = 0.9,... more Measurements are presented from proton-proton collisions at centre-of-mass energies of √ s = 0.9, 2.36 and 7 TeV recorded with the ATLAS detector at the LHC. Events were collected using a single-arm minimum-bias trigger. The charged-particle multiplicity, its dependence on transverse momentum and pseudorapidity and the relationship between the mean transverse momentum and charged-particle multiplicity are measured. Measurements in different regions of phase-space are shown, providing diffraction-reduced measurements as well as more inclusive ones. The observed distributions are corrected to well-defined phase-space regions, using model-independent corrections. The results are compared to each other and to various Monte Carlo models, including a new AMBT1 pythia6 tune. In all the kinematic regions considered, the particle multiplicities are higher than predicted by the Monte Carlo models. The central charged-particle multiplicity per event and unit of pseudorapidity, for tracks with p T > 100 MeV, is measured to be 3.483 ± 0.009 (stat) ± 0.106 (syst) at √ s = 0.9 TeV and 5.630 ± 0.003 (stat) ± 0.169 (syst) at √ s = 7 TeV.
Abstract In this paper, a measurement of τ polarization in W → τ ν decays is presented. It is mea... more Abstract In this paper, a measurement of τ polarization in W → τ ν decays is presented. It is measured from the energies of the decay products in hadronic τ decays with a single final state charged particle. The data, corresponding to an integrated luminosity of 24 pb −1 , were collected by the AT-LAS experiment at the Large Hadron Collider in 2010. The measured value of the τ polarization is P τ = −1.06 ± 0.04 (stat) +0.05 −0.07 (syst), in agreement with the Standard Model prediction, and is consistent with a physically allowed 95% CL interval [−1, −0.91]. Measurements of τ polarization have not previously been made at hadron colliders.
A measurement of the production cross section of top quark pairs (tt) in proton-proton collisions... more A measurement of the production cross section of top quark pairs (tt) in proton-proton collisions at a center-of-mass energy of 7 TeV recorded with the ATLAS detector at the Large Hadron Collider is reported. Candidate events are selected in the dilepton topology with large missing transverse energy and at least two jets. Using a data sample corresponding to an integrated luminosity of 35 pb −1 , a tt production cross section σ tt = 177 ± 20(stat.) ± 14(syst.) ± 7(lum.) pb is measured for an assumed top quark mass of m t = 172.5 GeV. A second measurement requiring at least one jet identified as coming from a b quark yields a comparable result, demonstrating that the dilepton final states are consistent with being accompanied by b-quark jets. These measurements are in good agreement with Standard Model predictions.
Proton-proton collisions at √ s = 7 TeV and heavy ion collisions at √ s NN = 2.76 TeV were produc... more Proton-proton collisions at √ s = 7 TeV and heavy ion collisions at √ s NN = 2.76 TeV were produced by the LHC and recorded using the ATLAS experiment's trigger system in 2010. The LHC is designed with a maximum bunch crossing rate of 40 MHz and the ATLAS trigger system is designed to record approximately 200 of these per second. The trigger system selects events by rapidly identifying signatures of muon, electron, photon, tau lepton, jet, and B meson candidates, as well as using global event signatures, such as missing transverse energy. An overview of the ATLAS trigger system, the evolution of the system during 2010 and the performance of the trigger system components and selections based on the 2010 collision data are shown. A brief outline of plans for the trigger system in 2011 is presented.
Karl Popper versus Theodor Adorno: Lessons from a historical confrontation. In 1961, during the C... more Karl Popper versus Theodor Adorno: Lessons from a historical confrontation. In 1961, during the Congress of the German Society of Sociology, two great theoretical references of the XX century faced in a historical debate about the logic of the social sciences. In addition to methodological issues strict sense, the confrontation became known as a debate between positivism and dialectic. The article first deals with the theoretical trajectories of Popper and Adorno and the relation of their theories with their political and ideological certainties. On one hand, the trajectory of the Popperian epistemology is examined, its contributions and vigorous attacks on Marx in what he called 'poverty of historicism" and false predictive Marxist world, and, on the other hand, the role of Adorno in the Frankfurt School, his criticism of totalitarianism and the defense of a critical emancipatory reason. The article also deals with the confrontation itself, the exposure of Popper's twenty-seven theses that culminate with the situation logic and the method of the economy as exemplary for the social sciences and Adorno's critical perspective of sociology and society as non-separable objects. In conclusion we show how the articulation of theory with the weltanschauung of each author helps to clarify the terms of the debate and how the confrontation contributed unequivocally to the dynamics of scientific progress and for the critical history of the ideas.
This paper is dedicated to the memory of our ATLAS colleagues who did not live to see the full im... more This paper is dedicated to the memory of our ATLAS colleagues who did not live to see the full impact and significance of their contributions to the experiment.
Proceedings of The National Academy of Sciences, 2001
Open reading frame expressed sequences tags (ORESTES) differ from conventional ESTs by providing ... more Open reading frame expressed sequences tags (ORESTES) differ from conventional ESTs by providing sequence data from the central protein coding portion of transcripts. We generated a total of 696,745 ORESTES sequences from 24 human tissues and used a subset of the data that correspond to a set of 15,095 full-length mRNAs as a means of assessing the efficiency of the strategy and its potential contribution to the definition of the human transcriptome. We estimate that ORESTES sampled over 80% of all highly and moderately expressed, and between 40% and 50% of rarely expressed, human genes. In our most thoroughly sequenced tissue, the breast, the 130,000 ORESTES generated are derived from transcripts from an estimated 70% of all genes expressed in that tissue, with an equally efficient representation of both highly and poorly expressed genes. In this respect, we find that the capacity of the ORESTES strategy both for gene discovery and shotgun transcript sequence generation significantly exceeds that of conventional ESTs. The distribution of ORESTES is such that many human transcripts are now represented by a scaffold of partial sequences distributed along the length of each gene product. The experimental joining of the scaffold components, by reverse transcription-PCR, represents a direct route to transcript finishing that may represent a useful alternative to full-length cDNA cloning.
A search for diphoton events with large missing transverse energy is presented. The data were col... more A search for diphoton events with large missing transverse energy is presented. The data were collected with the ATLAS detector in proton-proton collisions at √ s = 7 TeV at the CERN Large
A search for the electroweak pair production of charged sleptons and weak gauginos decaying into ... more A search for the electroweak pair production of charged sleptons and weak gauginos decaying into final states with two leptons is performed using 4.7 fb −1 of proton-proton collision data at √ s = 7 TeV recorded with the ATLAS experiment at the Large Hadron Collider. No significant excesses are observed with respect to the prediction from Standard Model processes. In the scenario of direct slepton production, if the sleptons decay directly into the lightest neutralino, left-handed slepton masses between 85 and 195 GeV are excluded at 95% confidence level for a 20 GeV neutralino. Chargino masses between 110 and 340 GeV are excluded in the scenario of direct production of wino-like chargino pairs decaying into the lightest neutralino via an intermediate on-shell charged slepton for a 10 GeV neutralino. The results are also interpreted in the framework of the phenomenological minimal supersymmetric Standard Model.
This paper describes the measurement of elliptic flow of charged particles in lead-lead collision... more This paper describes the measurement of elliptic flow of charged particles in lead-lead collisions at √ s NN = 2.76 TeV using the ATLAS detector at the Large Hadron Collider (LHC). The results are based on an integrated luminosity of approximately 7 µb −1 . Elliptic flow is measured over a wide region in pseudorapidity, |η| < 2.5, and over a broad range in transverse momentum, 0.5 < p T < 20 GeV. The elliptic flow parameter v 2 is obtained by correlating individual tracks with the event plane measured using energy deposited in the forward calorimeters. As a function of transverse momentum, v 2 (p T ) reaches a maximum at p T of about 3 GeV, then decreases and becomes weakly dependent on p T above 7-8 GeV. Over the measured pseudorapidity region, v 2 is found to be only weakly dependent on η, with less variation than observed at lower beam energies. The results are discussed in the context of previous measurements at lower collision energies, as well as recent results from the LHC.
The present article reviews the literature about the main contributions of fathers and siblings t... more The present article reviews the literature about the main contributions of fathers and siblings to the disabled individual development based on the family systems perspective. The purpose is to deepen the subject families of disabled people, focusing those elements that have been left in a second plan in studies of this area, father and siblings, showing their importance in the development of these individuals. Thus, aspects of the relation fatherindividual with special needs and siblingsindividual with special needs in literature are argued, elucidating the practical and methodological challenges of these studies that investigate such relations. One expects to contribute, in this analysis, for the interest increase in the related area.
Measurement of the centrality dependence of the charged particle pseudorapidity distribution in l... more Measurement of the centrality dependence of the charged particle pseudorapidity distribution in lead-lead collisions at √ s NN = 2.76 TeV with the ATLAS detector
Post-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the f... more Post-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the fact that there are many reports about the association of visceral leishmaniasis and AIDS, PKDL is very uncommon in HIV-positive patients, and so far only four cases have been documented in the literature. We present another case with unusual clinicopathological aspects. The patient, a 28-year-old male, from Salvador, Bahia (an endemic area) presented with clinical manifestations of visceral leishmaniasis three years after the diagnosis of AIDS. During treatment for visceral leishmaniasis he developed disseminated miliary papules. Microscopically, the skin biopsy showed a &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;saw-tooth&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot; pattern with a lichenoid mononuclear infiltrate simulating lichen planus. The histopathological diagnosis was achieved through the finding of amastigotes. The authors discuss the clinicopathological aspects of this case based on a review of the specific literature.
A comparative study between crotoxin and gamma irradiated crotoxin was performed on the indirectl... more A comparative study between crotoxin and gamma irradiated crotoxin was performed on the indirectly evoked twitches and tetani of sciatic nerve-extensor digitorum longus muscle of rats. Crotoxin (3 to 14 microg/ml) decreased the amplitude of twitches and induced a slight tetanic fade, and irradiated crotoxin did not significantly affect either twitch amplitude or tetanic tension. Since gamma radiation reduced the neurotoxicity of crotoxin it may be useful for the production of anticrotalic serum.
A search for production of supersymmetric particles in final states containing jets, missing tran... more A search for production of supersymmetric particles in final states containing jets, missing transverse momentum, and at least one hadronically decaying τ lepton is presented. The data were recorded by the ATLAS experiment in √ s = 7 TeV proton-proton collisions at the Large Hadron Collider. No excess above the Standard Model background expectation was observed in 2.05 fb −1 of data. The results are interpreted in the context of gauge mediated supersymmetry breaking models with M mess = 250 TeV, N 5 = 3, µ > 0, and C grav = 1. The production of supersymmetric particles is excluded at 95% C.L. up to a supersymmetry breaking scale Λ = 30 TeV, independent of tan β, and up to Λ = 43 TeV for large tan β.
Jaids-journal of Acquired Immune Deficiency Syndromes, 2008
Context-Since drug-involved women are among the fastest growing groups with AIDS, sexual risk red... more Context-Since drug-involved women are among the fastest growing groups with AIDS, sexual risk reduction intervention for them is a public health imperative.
Measurements are presented from proton-proton collisions at centre-of-mass energies of √ s = 0.9,... more Measurements are presented from proton-proton collisions at centre-of-mass energies of √ s = 0.9, 2.36 and 7 TeV recorded with the ATLAS detector at the LHC. Events were collected using a single-arm minimum-bias trigger. The charged-particle multiplicity, its dependence on transverse momentum and pseudorapidity and the relationship between the mean transverse momentum and charged-particle multiplicity are measured. Measurements in different regions of phase-space are shown, providing diffraction-reduced measurements as well as more inclusive ones. The observed distributions are corrected to well-defined phase-space regions, using model-independent corrections. The results are compared to each other and to various Monte Carlo models, including a new AMBT1 pythia6 tune. In all the kinematic regions considered, the particle multiplicities are higher than predicted by the Monte Carlo models. The central charged-particle multiplicity per event and unit of pseudorapidity, for tracks with p T > 100 MeV, is measured to be 3.483 ± 0.009 (stat) ± 0.106 (syst) at √ s = 0.9 TeV and 5.630 ± 0.003 (stat) ± 0.169 (syst) at √ s = 7 TeV.
Abstract In this paper, a measurement of τ polarization in W → τ ν decays is presented. It is mea... more Abstract In this paper, a measurement of τ polarization in W → τ ν decays is presented. It is measured from the energies of the decay products in hadronic τ decays with a single final state charged particle. The data, corresponding to an integrated luminosity of 24 pb −1 , were collected by the AT-LAS experiment at the Large Hadron Collider in 2010. The measured value of the τ polarization is P τ = −1.06 ± 0.04 (stat) +0.05 −0.07 (syst), in agreement with the Standard Model prediction, and is consistent with a physically allowed 95% CL interval [−1, −0.91]. Measurements of τ polarization have not previously been made at hadron colliders.
A measurement of the production cross section of top quark pairs (tt) in proton-proton collisions... more A measurement of the production cross section of top quark pairs (tt) in proton-proton collisions at a center-of-mass energy of 7 TeV recorded with the ATLAS detector at the Large Hadron Collider is reported. Candidate events are selected in the dilepton topology with large missing transverse energy and at least two jets. Using a data sample corresponding to an integrated luminosity of 35 pb −1 , a tt production cross section σ tt = 177 ± 20(stat.) ± 14(syst.) ± 7(lum.) pb is measured for an assumed top quark mass of m t = 172.5 GeV. A second measurement requiring at least one jet identified as coming from a b quark yields a comparable result, demonstrating that the dilepton final states are consistent with being accompanied by b-quark jets. These measurements are in good agreement with Standard Model predictions.
Proton-proton collisions at √ s = 7 TeV and heavy ion collisions at √ s NN = 2.76 TeV were produc... more Proton-proton collisions at √ s = 7 TeV and heavy ion collisions at √ s NN = 2.76 TeV were produced by the LHC and recorded using the ATLAS experiment's trigger system in 2010. The LHC is designed with a maximum bunch crossing rate of 40 MHz and the ATLAS trigger system is designed to record approximately 200 of these per second. The trigger system selects events by rapidly identifying signatures of muon, electron, photon, tau lepton, jet, and B meson candidates, as well as using global event signatures, such as missing transverse energy. An overview of the ATLAS trigger system, the evolution of the system during 2010 and the performance of the trigger system components and selections based on the 2010 collision data are shown. A brief outline of plans for the trigger system in 2011 is presented.
Karl Popper versus Theodor Adorno: Lessons from a historical confrontation. In 1961, during the C... more Karl Popper versus Theodor Adorno: Lessons from a historical confrontation. In 1961, during the Congress of the German Society of Sociology, two great theoretical references of the XX century faced in a historical debate about the logic of the social sciences. In addition to methodological issues strict sense, the confrontation became known as a debate between positivism and dialectic. The article first deals with the theoretical trajectories of Popper and Adorno and the relation of their theories with their political and ideological certainties. On one hand, the trajectory of the Popperian epistemology is examined, its contributions and vigorous attacks on Marx in what he called 'poverty of historicism" and false predictive Marxist world, and, on the other hand, the role of Adorno in the Frankfurt School, his criticism of totalitarianism and the defense of a critical emancipatory reason. The article also deals with the confrontation itself, the exposure of Popper's twenty-seven theses that culminate with the situation logic and the method of the economy as exemplary for the social sciences and Adorno's critical perspective of sociology and society as non-separable objects. In conclusion we show how the articulation of theory with the weltanschauung of each author helps to clarify the terms of the debate and how the confrontation contributed unequivocally to the dynamics of scientific progress and for the critical history of the ideas.
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Papers by Nancy Nunes