Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2007;22(12):871-81.
doi: 10.1007/s10654-007-9190-6. Epub 2007 Oct 10.

Modified Mediterranean diet and survival after myocardial infarction: the EPIC-Elderly study

Affiliations
Multicenter Study

Modified Mediterranean diet and survival after myocardial infarction: the EPIC-Elderly study

A Trichopoulou et al. Eur J Epidemiol. 2007.

Abstract

Mediterranean diet is associated with lower incidence of coronary heart disease, and two randomised trials indicated that it improves prognosis of coronary patients. These trials, however, relied on a total of 100 deaths and evaluated designer diets in the clinical context. We have evaluated the association of adherence to the modified Mediterranean diet, in which unsaturates were substituted for monounsaturates, with survival among elderly with previous myocardial infarction within the European Prospective Investigation into Cancer and nutrition (EPIC) study. As of December 2003, after a median follow-up of 6.7 years, 2671 EPIC participants from nine countries were 60 years or older and had prevalent myocardial infarction but no stroke or cancer at enrolment, complete information on dietary intakes and important covariates and known survival status. Adherence to the modified Mediterranean diet was assessed through a 10-unit-scale. Mortality ratio in relation to modified Mediterranean diet was estimated through Cox regression controlling for possible confounding. Increased adherence to modified Mediterranean diet by two units was associated with 18% lower overall mortality rate (95% confidence interval 7-27%, fixed effects model). There was no significant heterogeneity by sex, age at enrolment, or country, although the association tended to be less evident among northern Europeans. Associations between food groups contributing to the modified Mediterranean diet and mortality were generally weak. A diet inspired by the Mediterranean pattern that can be easily adopted by Western populations is associated with substantial reduction of total mortality of coronary patients in the community.

PubMed Disclaimer

References

    1. BMJ. 1995 Dec 2;311(7018):1457-60 - PubMed
    1. BMJ. 1996 Jul 13;313(7049):84-90 - PubMed
    1. N Engl J Med. 2003 Jun 26;348(26):2599-608 - PubMed
    1. Int J Epidemiol. 1997 Feb;26(1):155-9 - PubMed
    1. Circulation. 1999 Feb 16;99(6):779-85 - PubMed

Publication types

LinkOut - more resources