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Ernest Lee, MD, PhD

Photo of Ernest Lee, MD, PhD
Title(s)Assistant Professor, Dermatology
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSW, #4-25
San Francisco CA 94143
PronounsHe/Him/His
ORCID ORCID Icon0000-0001-5144-2552 Additional info
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    Collapse Biography 
    Collapse education and training
    California Institute of TechnologyBS2012Physics
    University of California, Los AngelesPhD2018Bioengineering
    David Geffen School of Medicine at UCLAMD2020Medicine
    Cedars-Sinai Medical CenterInternship2021Internal Medicine
    University of California, San FranciscoResidency2024Dermatology
    Collapse awards and honors
    UCSF2026ASCI Emerging-Generation Award
    UCSF2025Sandler Program for Breakthrough Biomedical Research, Postdoctoral Independent Research Grant
    UCSF2025Physician Scientist Career Development Award, Dermatology Foundation
    UCSF2025Society for Investigative Dermatology Travel Grant
    UCSF2024Hidradenitis Suppurativa Foundation Translational Research Grant
    UCSF2024Dermatologist Investigator Research Fellowship, Dermatology Foundation
    2021Forbes 30 under 30 in Science
    UCLA2020Emil Bogen Research Prize
    UCLA2019Alpha Omega Alpha Honor Society, Junior Member
    UCLA2019Edward K. Rice Outstanding Doctoral Student Award
    UCLA2018Department of Bioengineering Outstanding PhD Student Award
    UCLA2017National Psoriasis Foundation Early Career Research Grant
    UCLA2015Hertz Foundation Graduate Fellowship Finalist

    Collapse Overview 

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Computational discovery of precision therapeutics for hidradenitis suppurativa. bioRxiv. 2026 Feb 24. Lee EY, Leboit P, Naik HB, Tang AS, Vallania F, Yates AE, Klufas DM, Hansen SL, Rosenblum MD, Lowe MM, Sirota M. PMID: 41799800; PMCID: PMC12964703.
      View in: PubMed   Mentions:
    2. Artificial intelligence-enabled precision medicine for inflammatory skin diseases. J Invest Dermatol. 2026 Feb 14. Tang AS, Wei ML, Haemel A, La C, Sirota M, Lee EY. PMID: 41689579.
      View in: PubMed   Mentions:
    3. First, do NOHARM: towards clinically safe large language models. ArXiv. 2025 Dec 17. Wu D, Haredasht FN, Maharaj SK, Jain P, Tran J, Gwiazdon M, Rustagi A, Jindal J, Koshy JM, Kadiyala V, Agarwal A, Tappuni B, French B, Jesudasen S, Cosgriff CV, Chakraborty R, Caldwell J, Ziolkowski S, Iberri DJ, Diep R, Dalal RS, Newman KL, Galetta K, Pallais JC, Wei N, Buchheit KM, Hong DI, Lee EY, Shih A, Pahalyants V, Kaplan TB, Ravi V, Khemani S, Liang AS, Shirvani D, Patil A, Marshall N, Chopra K, Koh J, Badhwar A, McCoy LG, Wu DJH, Weng Y, Ranji S, Schulman K, Shah NH, Hom J, Milstein A, Rodman A, Chen JH, Goh E. PMID: 41532042; PMCID: PMC12794822.
      View in: PubMed   Mentions:
    4. Dynamics of Th1/Th17 responses and antimicrobial pathways in leprosy skin lesions. J Clin Invest. 2025 Sep 02; 135(17). Andrade PR, Ma F, Lu J, de Anda J, Lee EY, Agak GW, Dobry CJ, de Andrade Silva BJ, Teles RM, Mansky LA, Perrie J, Montoya DJ, Bryson BD, Gudjonsson JE, Wong GC, Sarno EN, Pellegrini M, Modlin RL. PMID: 40569678; PMCID: PMC12404764.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    5. Chemokines kill bacteria without triggering antimicrobial resistance by binding anionic phospholipids. Sci Adv. 2025 Jun 06; 11(23):eads2675. Pontejo SM, Martinez S, Zhao A, Barnes K, de Anda J, Alimohamadi H, Lee EY, Dishman AF, Volkman BF, Wong GCL, Garboczi DN, Ballesteros A, Murphy PM. PMID: 40479071; PMCID: PMC12143392.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Artificial intelligence-enabled precision medicine for inflammatory skin diseases. ArXiv. 2025 May 14. Tang A, Wei ML, Haemel A, La C, Sirota M, Lee EY. PMID: 40463698; PMCID: PMC12133082.
      View in: PubMed   Mentions:
    7. Transcriptomic analysis reveals immune signatures associated with specific cutaneous manifestations of lupus in systemic lupus erythematosus. bioRxiv. 2025 Apr 29. Lee EY, Patterson S, Cutts Z, Lanata CM, Dall'Era M, Yazdany J, Criswell LA, Haemel A, Katz P, Jimmie Ye C, Langelier C, Sirota M. PMID: 40488128; PMCID: PMC12143873.
      View in: PubMed   Mentions:
    8. The p12 Subunit Choreographs the Regulation and Functions of Two Forms of DNA Polymerase δ in Mammalian Cells. Genes (Basel). 2025 Feb 03; 16(2). Xu D, Ayyamperumal S, Zhang S, Chen J, Lee EYC, Lee MYWT. PMID: 40004517; PMCID: PMC11855201.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. Emerging Techniques in Spatial Multiomics: Fundamental Principles and Applications to Dermatology. J Invest Dermatol. 2025 May; 145(5):1017-1032. Jia BB, Sun BK, Lee EY, Ren B. PMID: 39503694.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Chemokines Kill Bacteria by Binding Anionic Phospholipids without Triggering Antimicrobial Resistance. bioRxiv. 2024 Jul 25. Pontejo SM, Martinez S, Zhao A, Barnes K, de Anda J, Alimohamadi H, Lee EY, Dishman AF, Volkman BF, Wong GCL, Garboczi DN, Ballesteros A, Murphy PM. PMID: 39091850; PMCID: PMC11291121.
      View in: PubMed   Mentions:
    11. Age and urban-rural disparities in cutaneous melanoma mortality rates in the United States during the COVID-19 pandemic. Pigment Cell Melanoma Res. 2024 11; 37(6):783-792. Hu T, Ma Z, Guo Y, Qiu S, Lv F, Liu Y, Ng WH, Zu J, Yeo YH, Ji F, Lee EY, Li Z. PMID: 38868930.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    12. Sweet syndrome in a patient with rectal adenocarcinoma and HIV following neoadjuvant chemoradiation. JAAD Case Rep. 2024 Jan; 43:72-75. Wilkerson K, Bradley FE, Lee EY, Cohen JN, Chang AY. PMID: 38234372; PMCID: PMC10793161.
      View in: PubMed   Mentions:
    13. The DHX9 helicase interacts with human DNA polymerase δ4 and stimulates its activity in D-loop extension synthesis. DNA Repair (Amst). 2023 08; 128:103513. Wang X, Zhang S, Zhang Z, Mazloum NA, Lee EYC, Lee MYW. PMID: 37285751; PMCID: PMC10330758.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. Excess psoriasis and psoriatic arthritis mortality during the COVID-19 pandemic in the United States: A nationwide population-based study from 2010 to 2021. J Eur Acad Dermatol Venereol. 2023 Jun; 37(6):1221-1227. Liu Y, He X, Lee EY, Lv F, Yao L, Meng Q, Zhang L, Ng WH, Zhang Y, Elias PM, Man M, Yeo YH, Li Z. PMID: 36808772.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    15. Severe recurrence of reactive infectious mucocutaneous eruption with extensive ocular involvement in an adult due to SARS-CoV-2. JAAD Case Rep. 2023 Jun; 36:1-3. Wu D, Lee EY, Lifton J, Zullo SW, Seiger K, Nadadur R, Fox LP, Escobar DJ, Dobry AS, Yung M, Kangelaris KN, Arakaki RY. PMID: 36819988; PMCID: PMC9931421.
      View in: PubMed   Mentions: 2  
    16. POLDIP3: At the Crossroad of RNA and DNA Metabolism. Genes (Basel). 2022 10 22; 13(11). Singh M, Zhang S, Perez AM, Lee EYC, Lee MYWT, Zhang D. PMID: 36360158; PMCID: PMC9690394.
      View in: PubMed   Mentions: 2     Fields:    
    17. DNA polymerase delta interacting protein 3 facilitates the activation and maintenance of DNA damage checkpoint in response to replication stress. Animal Model Exp Med. 2022 10; 5(5):461-469. Zhang S, Lee EYC, Lee MYWT, Zhang D. PMID: 36168146; PMCID: PMC9610138.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    18. Phenol-Soluble Modulins From Staphylococcus aureus Biofilms Form Complexes With DNA to Drive Autoimmunity. Front Cell Infect Microbiol. 2022; 12:884065. Grando K, Nicastro LK, Tursi SA, De Anda J, Lee EY, Wong GCL, Tükel Ç. PMID: 35646719; PMCID: PMC9131096.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    19. Histidine-Mediated Ion Specific Effects Enable Salt Tolerance of a Pore-Forming Marine Antimicrobial Peptide. Angew Chem Int Ed Engl. 2022 06 20; 61(25):e202108501. Xian W, Hennefarth MR, Lee MW, Do T, Lee EY, Alexandrova AN, Wong GCL. PMID: 35352449; PMCID: PMC9189074.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    20. Quantitative readability analysis of online patient educational materials for dermatofibrosarcoma protuberans. Int J Dermatol. 2022 05; 61(5):e196-e197. Kirchner A, Patel M, Kulkarni V, Usman A, Lee EY. PMID: 34165781.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Readability assessment of patient-facing online educational content for pyoderma gangrenosum. J Am Acad Dermatol. 2022 05; 86(5):1127-1128. Kirchner A, Kulkarni V, Rajkumar J, Usman A, Hassan S, Lee EY. PMID: 33882279.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. PACAP is a pathogen-inducible resident antimicrobial neuropeptide affording rapid and contextual molecular host defense of the brain. Proc Natl Acad Sci U S A. 2021 01 05; 118(1). Lee EY, Chan LC, Wang H, Lieng J, Hung M, Srinivasan Y, Wang J, Waschek JA, Ferguson AL, Lee KF, Yount NY, Yeaman MR, Wong GCL. PMID: 33372152; PMCID: PMC7817161.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    23. Ocular lichen planus treated with lifitegrast. Int J Dermatol. 2021 Jun; 60(6):e231-e233. Lee EY, Arzeno J, Ni C, Holland V. PMID: 32989726.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Discovery of Novel Type II Bacteriocins Using a New High-Dimensional Bioinformatic Algorithm. Front Immunol. 2020; 11:1873. Yount NY, Weaver DC, de Anda J, Lee EY, Lee MW, Wong GCL, Yeaman MR. PMID: 33013838; PMCID: PMC7494827.
      View in: PubMed   Mentions: 13     Fields:    
    25. Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation. Front Immunol. 2020; 11:1629. Lee EY, Srinivasan Y, de Anda J, Nicastro LK, Tükel Ç, Wong GCL. PMID: 32849553; PMCID: PMC7412598.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    26. Standing electric scooter injuries: Impact on a community. Am J Surg. 2021 01; 221(1):227-232. Bloom MB, Noorzad A, Lin C, Little M, Lee EY, Margulies DR, Torbati SS. PMID: 32778397; PMCID: PMC7933485.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    27. Machine learning for precision dermatology: Advances, opportunities, and outlook. J Am Acad Dermatol. 2021 May; 84(5):1458-1459. Lee EY, Maloney NJ, Cheng K, Bach DQ. PMID: 32645400; PMCID: PMC8023050.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    28. Telehealth Solutions for In-hospital Communication with Patients Under Isolation During COVID-19. West J Emerg Med. 2020 Jun 23; 21(4):801-806. Fang J, Liu YT, Lee EY, Yadav K. PMID: 32726245; PMCID: PMC7390554.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCellsPHPublic Health
    29. Switchable Membrane Remodeling and Antifungal Defense by Metamorphic Chemokine XCL1. ACS Infect Dis. 2020 05 08; 6(5):1204-1213. Dishman AF, Lee MW, de Anda J, Lee EY, He J, Huppler AR, Wong GCL, Volkman BF. PMID: 32243126; PMCID: PMC7258946.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    30. Circulating biomarkers predictive of tumor response to cancer immunotherapy. Expert Rev Mol Diagn. 2019 10; 19(10):895-904. Lee EY, Kulkarni RP. PMID: 31469965; PMCID: PMC6773262.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    31. Improved prediction of HIT in the SICU using an improved model of the Warkentin 4-T system: 3-T. Am J Surg. 2020 01; 219(1):54-57. Bloom MB, Johnson J, Volod O, Lee EY, White T, Margulies DR. PMID: 31400811; PMCID: PMC6917902.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    32. Two forms of human DNA polymerase δ: Who does what and why? DNA Repair (Amst). 2019 09; 81:102656. Lee MYWT, Zhang S, Wang X, Chao HH, Zhao H, Darzynkiewicz Z, Zhang Z, Lee EYC. PMID: 31326365.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    33. Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death. Nature. 2019 05; 569(7755):236-240. Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gómez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, González-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O. PMID: 31043745; PMCID: PMC6716525.
      View in: PubMed   Mentions: 235     Fields:    Translation:AnimalsCells
    34. CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-α production in systemic sclerosis. Nat Commun. 2019 05 01; 10(1):1731. Lande R, Lee EY, Palazzo R, Marinari B, Pietraforte I, Santos GS, Mattenberger Y, Spadaro F, Stefanantoni K, Iannace N, Dufour AM, Falchi M, Bianco M, Botti E, Bianchi L, Alvarez M, Riccieri V, Truchetet ME, C L Wong G, Chizzolini C, Frasca L. PMID: 31043596; PMCID: PMC6494823.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    35. Off-label studies on apremilast in dermatology: a review. J Dermatolog Treat. 2020 Mar; 31(2):131-140. Maloney NJ, Zhao J, Tegtmeyer K, Lee EY, Cheng K. PMID: 30935262; PMCID: PMC6774908.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    36. Unifying structural signature of eukaryotic α-helical host defense peptides. Proc Natl Acad Sci U S A. 2019 04 02; 116(14):6944-6953. Yount NY, Weaver DC, Lee EY, Lee MW, Wang H, Chan LC, Wong GCL, Yeaman MR. PMID: 30877253; PMCID: PMC6452647.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    37. Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9. Nat Commun. 2019 03 04; 10(1):1012. Lee EY, Zhang C, Di Domizio J, Jin F, Connell W, Hung M, Malkoff N, Veksler V, Gilliet M, Ren P, Wong GCL. PMID: 30833557; PMCID: PMC6399285.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    38. Machine learning antimicrobial peptide sequences: Some surprising variations on the theme of amphiphilic assembly. Curr Opin Colloid Interface Sci. 2018 Nov; 38:204-213. Lee MW, Lee EY, Ferguson AL, Wong GCL. PMID: 31093008; PMCID: PMC6513345.
      View in: PubMed   Mentions: 11  
    39. Discovery of a novel DNA polymerase inhibitor and characterization of its antiproliferative properties. Cancer Biol Ther. 2019; 20(4):474-486. Mishra B, Zhang S, Zhao H, Darzynkiewicz Z, Lee EYC, Lee MYWT, Zhang Z. PMID: 30427259; PMCID: PMC6422523.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    40. Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis. iScience. 2018 Aug 31; 6:52-67. Peddu C, Zhang S, Zhao H, Wong A, Lee EYC, Lee MYWT, Zhang Z. PMID: 30240625; PMCID: PMC6137289.
      View in: PubMed   Mentions: 6  
    41. What Can Pleiotropic Proteins in Innate Immunity Teach Us about Bioconjugation and Molecular Design? Bioconjug Chem. 2018 07 18; 29(7):2127-2139. Lee MW, Lee EY, Wong GCL. PMID: 29771496; PMCID: PMC6540093.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    42. Multigenerational memory and adaptive adhesion in early bacterial biofilm communities. Proc Natl Acad Sci U S A. 2018 04 24; 115(17):4471-4476. Lee CK, de Anda J, Baker AE, Bennett RR, Luo Y, Lee EY, Keefe JA, Helali JS, Ma J, Zhao K, Golestanian R, O'Toole GA, Wong GCL. PMID: 29559526; PMCID: PMC5924909.
      View in: PubMed   Mentions: 83     Fields:    Translation:Cells
    43. Cathelicidin promotes inflammation by enabling binding of self-RNA to cell surface scavenger receptors. Sci Rep. 2018 03 05; 8(1):4032. Takahashi T, Kulkarni NN, Lee EY, Zhang LJ, Wong GCL, Gallo RL. PMID: 29507358; PMCID: PMC5838106.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    44. Modulation of toll-like receptor signaling by antimicrobial peptides. Semin Cell Dev Biol. 2019 04; 88:173-184. Lee EY, Lee MW, Wong GCL. PMID: 29432957; PMCID: PMC6087683.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    45. Molecular Motor Dnm1 Synergistically Induces Membrane Curvature To Facilitate Mitochondrial Fission. ACS Cent Sci. 2017 Nov 22; 3(11):1156-1167. Lee MW, Lee EY, Lai GH, Kennedy NW, Posey AE, Xian W, Ferguson AL, Hill RB, Wong GCL. PMID: 29202017; PMCID: PMC5704292.
      View in: PubMed   Mentions: 22  
    46. What can machine learning do for antimicrobial peptides, and what can antimicrobial peptides do for machine learning? Interface Focus. 2017 Dec 06; 7(6):20160153. Lee EY, Lee MW, Fulan BM, Ferguson AL, Wong GCL. PMID: 29147555; PMCID: PMC5665795.
      View in: PubMed   Mentions: 57  
    47. Crystallinity of Double-Stranded RNA-Antimicrobial Peptide Complexes Modulates Toll-Like Receptor 3-Mediated Inflammation. ACS Nano. 2017 12 26; 11(12):12145-12155. Lee EY, Takahashi T, Curk T, Dobnikar J, Gallo RL, Wong GCL. PMID: 29016111; PMCID: PMC5936640.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    48. High-Speed "4D" Computational Microscopy of Bacterial Surface Motility. ACS Nano. 2017 09 26; 11(9):9340-9351. de Anda J, Lee EY, Lee CK, Bennett RR, Ji X, Soltani S, Harrison MC, Baker AE, Luo Y, Chou T, O'Toole GA, Armani AM, Golestanian R, Wong GCL. PMID: 28836761; PMCID: PMC5978429.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    49. Regulation and Modulation of Human DNA Polymerase δ Activity and Function. Genes (Basel). 2017 Jul 24; 8(7). Lee MYWT, Wang X, Zhang S, Zhang Z, Lee EYC. PMID: 28737709; PMCID: PMC5541323.
      View in: PubMed   Mentions: 28     Fields:    
    50. Machine learning-enabled discovery and design of membrane-active peptides. Bioorg Med Chem. 2018 06 01; 26(10):2708-2718. Lee EY, Wong GCL, Ferguson AL. PMID: 28728899; PMCID: PMC5758442.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimals
    51. A Role for Neuronal Alpha-Synuclein in Gastrointestinal Immunity. J Innate Immun. 2017; 9(5):456-463. Stolzenberg E, Berry D, Lee EY, Kroemer A, Kaufman S, Wong GCL, Oppenheim JJ, Sen S, Fishbein T, Bax A, Harris B, Barbut D, Zasloff MA. PMID: 28651250; PMCID: PMC5865636.
      View in: PubMed   Mentions: 157     Fields:    Translation:HumansCells
    52. Direct Antimicrobial Activity of IFN-β. J Immunol. 2017 05 15; 198(10):4036-4045. Kaplan A, Lee MW, Wolf AJ, Limon JJ, Becker CA, Ding M, Murali R, Lee EY, Liu GY, Wong GCL, Underhill DM. PMID: 28411186; PMCID: PMC5469413.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    53. Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9. PLoS Pathog. 2017 Apr; 13(4):e1006315. Tursi SA, Lee EY, Medeiros NJ, Lee MH, Nicastro LK, Buttaro B, Gallucci S, Wilson RP, Wong GCL, Tükel Ç. PMID: 28410407; PMCID: PMC5406031.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    54. Mapping membrane activity in undiscovered peptide sequence space using machine learning. Proc Natl Acad Sci U S A. 2016 11 29; 113(48):13588-13593. Lee EY, Fulan BM, Wong GC, Ferguson AL. PMID: 27849600; PMCID: PMC5137689.
      View in: PubMed   Mentions: 71     Fields:    Translation:Cells
    55. S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages. PLoS Pathog. 2016 06; 12(6):e1005705. Realegeno S, Kelly-Scumpia KM, Dang AT, Lu J, Teles R, Liu PT, Schenk M, Lee EY, Schmidt NW, Wong GC, Sarno EN, Rea TH, Ochoa MT, Pellegrini M, Modlin RL. PMID: 27355424; PMCID: PMC4927120.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    56. Oxidation of Membrane Curvature-Regulating Phosphatidylethanolamine Lipid Results in Formation of Bilayer and Cubic Structures. Langmuir. 2016 Mar 15; 32(10):2450-7. Sankhagowit S, Lee EY, Wong GC, Malmstadt N. PMID: 26866900; PMCID: PMC6559366.
      View in: PubMed   Mentions: 10     Fields:    
    57. A review of immune amplification via ligand clustering by self-assembled liquid-crystalline DNA complexes. Adv Colloid Interface Sci. 2016 06; 232:17-24. Lee EY, Lee CK, Schmidt NW, Jin F, Lande R, Curk T, Frenkel D, Dobnikar J, Gilliet M, Wong GCL. PMID: 26956527; PMCID: PMC6519935.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    58. PDIP46 (DNA polymerase δ interacting protein 46) is an activating factor for human DNA polymerase δ. Oncotarget. 2016 Feb 02; 7(5):6294-313. Wang X, Zhang S, Zheng R, Yue F, Lin SH, Rahmeh AA, Lee EY, Zhang Z, Lee MY. PMID: 26819372; PMCID: PMC4868757.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    59. Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase δ revealed in individual cells by cytometry. Oncotarget. 2015 May 20; 6(14):11735-50. Darzynkiewicz Z, Zhao H, Zhang S, Lee MY, Lee EY, Zhang Z. PMID: 26059433; PMCID: PMC4494901.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    60. The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression. Cell Cycle. 2014; 13(1):23-31. Lee MY, Zhang S, Lin SH, Wang X, Darzynkiewicz Z, Zhang Z, Lee EY. PMID: 24300032; PMCID: PMC3925730.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    61. PDIP38 is translocated to the spliceosomes/nuclear speckles in response to UV-induced DNA damage and is required for UV-induced alternative splicing of MDM2. Cell Cycle. 2013 Oct 01; 12(19):3184-93. Wong A, Zhang S, Mordue D, Wu JM, Zhang Z, Darzynkiewicz Z, Lee EY, Lee MY. PMID: 23989611; PMCID: PMC3865014.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    62. A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase. J Biol Chem. 2013 Oct 11; 288(41):29550-61. Zhang S, Zhao H, Darzynkiewicz Z, Zhou P, Zhang Z, Lee EY, Lee MY. PMID: 23913683; PMCID: PMC3795253.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    63. Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage. J Biol Chem. 2013 Feb 01; 288(5):2941-50. Zhang S, Zhou Y, Sarkeshik A, Yates JR, Thomson TM, Zhang Z, Lee EY, Lee MY. PMID: 23233665; PMCID: PMC3561517.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    64. Regulation of human DNA polymerase delta in the cellular responses to DNA damage. Environ Mol Mutagen. 2012 Dec; 53(9):683-98. Lee MY, Zhang S, Lin SH, Chea J, Wang X, LeRoy C, Wong A, Zhang Z, Lee EY. PMID: 23047826.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    65. Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage. Cell Cycle. 2012 Aug 01; 11(15):2885-95. Chea J, Zhang S, Zhao H, Zhang Z, Lee EY, Darzynkiewicz Z, Lee MY. PMID: 22801543; PMCID: PMC3419061.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    66. Characterization of human DNA polymerase delta and its subassemblies reconstituted by expression in the MultiBac system. PLoS One. 2012; 7(6):e39156. Zhou Y, Meng X, Zhang S, Lee EY, Lee MY. PMID: 22723953; PMCID: PMC3377666.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    67. Structure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment maturation. Cell Cycle. 2012 Jun 01; 11(11):2128-36. Zhang Z, Zhang S, Lin SH, Wang X, Wu L, Lee EY, Lee MY. PMID: 22592530; PMCID: PMC3368864.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    68. P50, the small subunit of DNA polymerase delta, is required for mediation of the interaction of polymerase delta subassemblies with PCNA. PLoS One. 2011; 6(11):e27092. Wang Y, Zhang Q, Chen H, Li X, Mai W, Chen K, Zhang S, Lee EY, Lee MY, Zhou Y. PMID: 22073260; PMCID: PMC3206906.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    69. Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor. PLoS One. 2011; 6(7):e22224. Zhou Y, Chen H, Li X, Wang Y, Chen K, Zhang S, Meng X, Lee EY, Lee MY. PMID: 21789240; PMCID: PMC3137619.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    70. The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis. Biochemistry. 2010 May 04; 49(17):3545-54. Meng X, Zhou Y, Lee EY, Lee MY, Frick DN. PMID: 20334433; PMCID: PMC2860660.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    71. DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers. Nucleic Acids Res. 2009 Feb; 37(2):647-57. Meng X, Zhou Y, Zhang S, Lee EY, Frick DN, Lee MY. PMID: 19074196; PMCID: PMC2632934.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    72. PCNA is ubiquitinated by RNF8. Cell Cycle. 2008 Nov 01; 7(21):3399-404. Zhang S, Chea J, Meng X, Zhou Y, Lee EY, Lee MY. PMID: 18948756.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    73. Identification of the interaction sites of Inhibitor-3 for protein phosphatase-1. Biochem Biophys Res Commun. 2008 Dec 12; 377(2):710-713. Zhang L, Qi Z, Gao Y, Lee EYC. PMID: 18951879; PMCID: PMC2613339.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    74. Protein phosphatase-1 is targeted to DNA polymerase delta via an interaction with the p68 subunit. Biochemistry. 2008 Oct 28; 47(43):11367-76. Gao Y, Zhou Y, Xie B, Zhang S, Rahmeh A, Huang HS, Lee MY, Lee EY. PMID: 18826257.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    75. Protein phosphatase-1 inhibitor-3 is an in vivo target of caspase-3 and participates in the apoptotic response. J Biol Chem. 2008 Jun 27; 283(26):18135-46. Huang HS, Lee EY. PMID: 18450750; PMCID: PMC2440612.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    76. A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta. J Biol Chem. 2007 May 25; 282(21):15330-40. Zhang S, Zhou Y, Trusa S, Meng X, Lee EY, Lee MY. PMID: 17317665.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    77. Functional roles of p12, the fourth subunit of human DNA polymerase delta. J Biol Chem. 2006 May 26; 281(21):14748-55. Li H, Xie B, Zhou Y, Rahmeh A, Trusa S, Zhang S, Gao Y, Lee EY, Lee MY. PMID: 16510448.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    78. Protein phosphatase-1 inhibitor-3 is co-localized to the nucleoli and centrosomes with PP1gamma1 and PP1alpha, respectively. Arch Biochem Biophys. 2005 Nov 15; 443(1-2):33-44. Huang HS, Pozarowski P, Gao Y, Darzynkiewicz Z, Lee EY. PMID: 16256067.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
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