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Comparison of PU.1 genomic binding across immune cells reveals cell type-specific roles in autoimmune disease. medRxiv. 2026 Jan 27.
Lewis DA, Shook MS, Lawson LP, Parameswaran S, Chen X, Edsall LE, Donmez OA, Yin C, Rosado-Tristani DA, VonHandorf A, Dexheimer PJ, Forney CR, Felton JM, Diouf AA, Dunn KA, Smith DF, Rothenberg ME, Seidman JS, Troutman TD, Glass CK, Waggoner SN, Weirauch MT, Kottyan LC. PMID: 41646676; PMCID: PMC12870612.
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Systemically inducing trained immunity overcomes solid tumors' immunosuppressive microenvironment. Sci Adv. 2026 Jan 02; 12(1):eadu0292.
Priem B, Willemsen L, Anbergen T, van Elsas Y, Deckers J, Schrijver DP, Hofstraat SRJ, Messing IV, Munitz J, Honing D, Prévot G, Toner YC, Morla J, Wang W, Ranzenigo A, Sirchia I, Post T, Duivenvoorden R, Kluza E, Cremers GAO, Kreijtz JHCM, Pérez-Medina C, van Leent MMT, Teunissen AJP, van der Meel R, Zhou Y, Glass C, Ochando J, Joosten LAB, Fayad ZA, Netea-Maier RT, Netea MG, de Winther MPJ, Beldman TJ, Griffioen AW, Mulder WJM. PMID: 41477842; PMCID: PMC12757067.
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Transcriptional and epigenetic targets of MEF2C in human microglia contribute to cellular functions related to autism risk and age-related disease. Nat Immunol. 2025 Nov; 26(11):1989-2003.
Nguyen C, Broersma EH, Warden AS, Mora C, Han CZ, Keulen Z, Spann N, Wang J, Ramirez G, Mak S, Trescott S, Khakpour M, Johnson A, Qureshi F, La Frano MR, Mohajeri K, Talkowski ME, Corradin O, Tremblay MÈ, Glass CK, Coufal NG. PMID: 41125877; PMCID: PMC12571900.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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CCL26 and CXCL12 preserve insulin-sensitizing macrophages in subcutaneous adipose tissue in obesity. Cell Rep. 2025 Oct 28; 44(10):116450.
Jeelani I, Franco da Cunha F, Rohm TV, Nasamran CA, Wang L, Moon JS, Prakash S, Oswari J, Isaac R, Murphy C, Glass CK, Olefsky JM, Lee YS. PMID: 41100258; PMCID: PMC12587491.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Global human myeloid replacement with peripheral progenitors induces interferonopathy and neurodegeneration. Res Sq. 2025 Oct 03.
Wang J, Warden A, Xia B, Mostoller KE, Brandon B, Du M, Spann N, Li RZ, Parast MM, Mestan K, Qureshi F, Corradin O, Glass C, Coufal NG. PMID: 41256000; PMCID: PMC12622173.
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PubMed Mentions:
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Microglia networks within the tapestry of alzheimer's disease through spatial transcriptomics. Mol Neurodegener. 2025 Sep 29; 20(1):102.
Zhou Y, Glass CK. PMID: 41024223; PMCID: PMC12482212.
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PubMed Mentions:
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CCL26 and CXCL12 Promote Release of Insulin-Sensitizing Adipose Tissue Macrophage sEVs from Subcutaneous Adipose Tissue in Obesity. bioRxiv. 2025 Aug 24.
Jeelani I, da Cunha FF, Rohm TV, Nasamran CA, Moon JS, Wang L, Prakash S, Issac R, Murphy C, Glass CK, Olefsky JM, Lee YS. PMID: 40894782; PMCID: PMC12393446.
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PubMed Mentions:
1
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Genetic variation in the activity of a TREM2-p53 signaling axis determines oxygen-induced lung injury. Nat Immunol. 2025 Aug; 26(8):1287-1298.
Abe Y, Spann NJ, Tang W, Zeng F, Seymour C, Jansky S, Guo JL, Huff R, Chanthavixay K, Richard JLC, Mooney M, Dhar D, Ganguly S, Lopez DM, Longaker MT, Benner C, Glass CK, Sajti E. PMID: 40715658; PMCID: PMC12456008.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Self-amplifying NRF2-EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer. Nat Cancer. 2025 Jul; 6(7):1263-1282.
Antonucci L, Li N, Duran A, Cobo I, Nicoletti C, Watari K, Nandi SP, Zhu F, Zhao Y, Riahi I, Tsuda M, Shah VM, Morgan T, Waugh T, Caputo L, Liu Y, Rundberg Nilsson A, Xian H, Todoric J, Gu L, Sanchez-Lopez E, Eibl G, Vucic EA, Krawczyk M, Xu Q, Lowy AM, Hatzivassiliou G, Roose-Girma M, Skowronska-Krawczyk D, Scott DA, Bar-Sagi D, Tamayo P, Wu Y, Sears RC, Glass CK, Alexandrov LB, Puri PL, Dawson DW, Hu Y, Diaz-Meco MT, Moscat J, Karin M. PMID: 40588523; PMCID: PMC12331375.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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The inactive X chromosome drives sex differences in microglial inflammatory activity in human glioblastoma. bioRxiv. 2025 May 19.
Tharp ME, Han CZ, Talukdar M, Balak CD, Fitzpatrick C, Connor CO, Preissl S, Buchanan J, Nott A, Escoubet L, Mavrommatis K, Gupta M, Schwartz MS, U HS, Jones PS, Levy ML, Gonda DD, Ben-Haim S, Ciacci J, Barba D, Khalessi A, Coufal NG, Chen CC, Glass CK, Page DC. PMID: 38895459; PMCID: PMC11185629.
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PubMed Mentions:
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Machine-guided cell-fate engineering. Cell Rep. 2025 Jun 24; 44(6):115726.
Appleton E, Tao J, Liu S, Glass C, Fonseca G, Church G. PMID: 40382774.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression. Immunity. 2025 Apr 08; 58(4):826-842.e8.
Cobo I, Murillo-Saich J, Alishala M, Calderon S, Coras R, Hemming B, Inkum F, Rosas F, Takei R, Spann N, Prohaska TA, Alabarse PVG, Jeong SJ, Nickl CK, Cheng A, Li B, Vogel A, Weichhart T, Fuster JJ, Le T, Bradstreet TR, Webber AM, Edelson BT, Razani B, Ebert BL, Taneja R, Terkeltaub R, Bryan RL, Guma M, Glass CK. PMID: 40118070; PMCID: PMC12093573.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression. Immunity. 2025 Feb 11; 58(2):326-343.e11.
McManus RM, Komes MP, Griep A, Santarelli F, Schwartz S, Ramón Perea J, Schlachetzki JCM, Bouvier DS, Khalil MA, Lauterbach MA, Heinemann L, Schlüter T, Pour MS, Lovotti M, Stahl R, Duthie F, Rodríguez-Alcázar JF, Schmidt SV, Spitzer J, Noori P, Maillo A, Boettcher A, Herron B, McConville J, Gomez-Cabrero D, Tegnér J, Glass CK, Hiller K, Latz E, Heneka MT. PMID: 39904338.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Neuroinflammation in Alzheimer disease. Nat Rev Immunol. 2025 May; 25(5):321-352.
Heneka MT, van der Flier WM, Jessen F, Hoozemanns J, Thal DR, Boche D, Brosseron F, Teunissen C, Zetterberg H, Jacobs AH, Edison P, Ramirez A, Cruchaga C, Lambert JC, Laza AR, Sanchez-Mut JV, Fischer A, Castro-Gomez S, Stein TD, Kleineidam L, Wagner M, Neher JJ, Cunningham C, Singhrao SK, Prinz M, Glass CK, Schlachetzki JCM, Butovsky O, Kleemann K, De Jaeger PL, Scheiblich H, Brown GC, Landreth G, Moutinho M, Grutzendler J, Gomez-Nicola D, McManus RM, Andreasson K, Ising C, Karabag D, Baker DJ, Liddelow SA, Verkhratsky A, Tansey M, Monsonego A, Aigner L, Dorothée G, Nave KA, Simons M, Constantin G, Rosenzweig N, Pascual A, Petzold GC, Kipnis J, Venegas C, Colonna M, Walter J, Tenner AJ, O'Banion MK, Steinert JR, Feinstein DL, Sastre M, Bhaskar K, Hong S, Schafer DP, Golde T, Ransohoff RM, Morgan D, Breitner J, Mancuso R, Riechers SP. PMID: 39653749.
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PubMed Mentions:
66 Fields:
Translation:
HumansAnimals
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Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model. bioRxiv. 2024 Nov 14.
Balak CD, Schlachetzki JCM, Lana AJ, West E, Hong C, DuGal J, Zhou Y, Li B, Saisan P, Spann NJ, Sarsani V, Pasillas MP, O'Brien S, Gordts P, Stevens B, Kamme F, Glass CK. PMID: 39605454; PMCID: PMC11601307.
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Multi-modal analysis of human hepatic stellate cells identifies novel therapeutic targets for metabolic dysfunction-associated steatotic liver disease. J Hepatol. 2025 May; 82(5):882-897.
Kim HY, Rosenthal SB, Liu X, Miciano C, Hou X, Miller M, Buchanan J, Poirion OB, Chilin-Fuentes D, Han C, Housseini M, Carvalho-Gontijo Weber R, Sakane S, Lee W, Zhao H, Diggle K, Preissl S, Glass CK, Ren B, Wang A, Brenner DA, Kisseleva T. PMID: 39522884; PMCID: PMC12306656.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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The human milk oligosaccharide 3'sialyllactose reduces low-grade inflammation and atherosclerosis development in mice. JCI Insight. 2024 Nov 08; 9(21).
Pessentheiner AR, Spann NJ, Autran CA, Oh TG, Grunddal KV, Coker JK, Painter CD, Ramms B, Chiang AW, Wang CY, Hsiao J, Wang Y, Quach A, Booshehri LM, Hammond A, Tognaccini C, Latasiewicz J, Willemsen L, Zengler K, de Winther MP, Hoffman HM, Philpott M, Cribbs AP, Oppermann U, Lewis NE, Witztum JL, Yu R, Atkins AR, Downes M, Evans RM, Glass CK, Bode L, Gordts PL. PMID: 39325548; PMCID: PMC11601559.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Correction: Gene expression and chromatin conformation of microglia in virally suppressed people with HIV. Life Sci Alliance. 2025 Jan; 8(1).
Schlachetzki JC, Gianella S, Ouyang Z, Lana AJ, Yang X, O'Brien S, Challacombe JF, Gaskill PJ, Jordan-Sciutto KL, Chaillon A, Moore D, Achim CL, Ellis RJ, Smith DM, Glass CK. PMID: 39467638; PMCID: PMC11519389.
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PubMed Mentions: Fields:
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Isolation and Cryopreservation of Highly Viable Human Peripheral Blood Mononuclear Cells From Whole Blood: A Guide for Beginners. J Vis Exp. 2024 Oct 25; (212).
Dinh B, Hoeksema MA, Spann NJ, Rendler J, Cobo I, Glass CK, Yeang C. PMID: 39526601.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2. NPJ Parkinsons Dis. 2024 Oct 22; 10(1):192.
Ging K, Frick L, Schlachetzki J, Armani A, Zhu Y, Gilormini PA, Dhingra A, Böck D, Marques A, Deen M, Chen X, Serdiuk T, Trevisan C, Sellitto S, Pisano C, Glass CK, Heutink P, Yin JA, Vocadlo DJ, Aguzzi A. PMID: 39438499; PMCID: PMC11496744.
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PubMed Mentions:
1
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Proinflammatory immune cells disrupt angiogenesis and promote germinal matrix hemorrhage in prenatal human brain. Nat Neurosci. 2024 Nov; 27(11):2115-2129.
Chen J, Crouch EE, Zawadzki ME, Jacobs KA, Mayo LN, Choi JJ, Lin PY, Shaikh S, Tsui J, Gonzalez-Granero S, Waller S, Kelekar A, Kang G, Valenzuela EJ, Birrueta JO, Diafos LN, Wedderburn-Pugh K, Di Marco B, Xia W, Han CZ, Coufal NG, Glass CK, Fancy SPJ, Alfonso J, Kriegstein AR, Oldham MC, Garcia-Verdugo JM, Kutys ML, Lehtinen MK, Combes AJ, Huang EJ. PMID: 39349662; PMCID: PMC11537974.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Lipid-associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2. Proc Natl Acad Sci U S A. 2024 Aug 27; 121(35):e2405746121.
Ganguly S, Rosenthal SB, Ishizuka K, Troutman TD, Rohm TV, Khader N, Aleman-Muench G, Sano Y, Archilei S, Soroosh P, Olefsky JM, Feldstein AE, Kisseleva T, Loomba R, Glass CK, Brenner DA, Dhar D. PMID: 39172787; PMCID: PMC11363294.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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TIANA: transcription factors cooperativity inference analysis with neural attention. BMC Bioinformatics. 2024 Aug 22; 25(1):274.
Li RZ, Han CZ, Glass CK. PMID: 39174927; PMCID: PMC11342676.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Gene expression and chromatin conformation of microglia in virally suppressed people with HIV. Life Sci Alliance. 2024 Oct; 7(10).
Schlachetzki JC, Gianella S, Ouyang Z, Lana AJ, Yang X, O'Brien S, Challacombe JF, Gaskill PJ, Jordan-Sciutto KL, Chaillon A, Moore D, Achim CL, Ellis RJ, Smith DM, Glass CK. PMID: 39060113; PMCID: PMC11282357.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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APOE4/4 is linked to damaging lipid droplets in Alzheimer's disease microglia. Nature. 2024 Apr; 628(8006):154-161.
Haney MS, Pálovics R, Munson CN, Long C, Johansson PK, Yip O, Dong W, Rawat E, West E, Schlachetzki JCM, Tsai A, Guldner IH, Lamichhane BS, Smith A, Schaum N, Calcuttawala K, Shin A, Wang YH, Wang C, Koutsodendris N, Serrano GE, Beach TG, Reiman EM, Glass CK, Abu-Remaileh M, Enejder A, Huang Y, Wyss-Coray T. PMID: 38480892; PMCID: PMC10990924.
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PubMed Mentions:
203 Fields:
Translation:
HumansAnimalsCells
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The nuclear factor ID3 endows macrophages with a potent anti-tumour activity. Nature. 2024 Feb; 626(8000):864-873.
Deng Z, Loyher PL, Lazarov T, Li L, Shen Z, Bhinder B, Yang H, Zhong Y, Alberdi A, Massague J, Sun JC, Benezra R, Glass CK, Elemento O, Iacobuzio-Donahue CA, Geissmann F. PMID: 38326607; PMCID: PMC10881399.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Deciphering microglia phenotypes in health and disease. Curr Opin Genet Dev. 2024 02; 84:102146.
Balak CD, Han CZ, Glass CK. PMID: 38171044; PMCID: PMC12118495.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proc Natl Acad Sci U S A. 2024 Jan 09; 121(2):e2316104121.
Abe Y, Kofman ER, Ouyang Z, Cruz-Becerra G, Spann NJ, Seidman JS, Troutman TD, Stender JD, Taylor H, Fan W, Link VM, Shen Z, Sakai J, Downes M, Evans RM, Kadonaga JT, Rosenfeld MG, Glass CK. PMID: 38165941; PMCID: PMC10786282.
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PubMed Mentions:
14 Fields:
Translation:
Cells
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Interpretation of Neurodegenerative GWAS Risk Alleles in Microglia and their Interplay with Other Cell Types. Adv Neurobiol. 2024; 37:531-544.
Holtman IR, Glass CK, Nott A. PMID: 39207711.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression. Mol Cell. 2023 10 05; 83(19):3421-3437.e11.
Abe Y, Kofman ER, Almeida M, Ouyang Z, Ponte F, Mueller JR, Cruz-Becerra G, Sakai M, Prohaska TA, Spann NJ, Resende-Coelho A, Seidman JS, Stender JD, Taylor H, Fan W, Link VM, Cobo I, Schlachetzki JCM, Hamakubo T, Jepsen K, Sakai J, Downes M, Evans RM, Yeo GW, Kadonaga JT, Manolagas SC, Rosenfeld MG, Glass CK. PMID: 37751740; PMCID: PMC10591845.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes. Nat Immunol. 2023 11; 24(11):1825-1838.
Bennett H, Troutman TD, Zhou E, Spann NJ, Link VM, Seidman JS, Nickl CK, Abe Y, Sakai M, Pasillas MP, Marlman JM, Guzman C, Hosseini M, Schnabl B, Glass CK. PMID: 37735593; PMCID: PMC10602851.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Correction: A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice. Elife. 2023 Aug 31; 12.
Abdel-Haq R, Schlachetzki JCM, Boktor JC, Cantu-Jungles TM, Thron T, Zhang M, Bostick JW, Khazaei T, Chilakala S, Morais LH, Humphrey G, Keshavarzian A, Katz JE, Thomson M, Knight R, Gradinaru V, Hamaker BR, Glass CK, Mazmanian SK. PMID: 37650862; PMCID: PMC10471158.
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PubMed Mentions:
1 Fields:
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Human microglia maturation is underpinned by specific gene regulatory networks. Immunity. 2023 09 12; 56(9):2152-2171.e13.
Han CZ, Li RZ, Hansen E, Trescott S, Fixsen BR, Nguyen CT, Mora CM, Spann NJ, Bennett HR, Poirion O, Buchanan J, Warden AS, Xia B, Schlachetzki JCM, Pasillas MP, Preissl S, Wang A, O'Connor C, Shriram S, Kim R, Schafer D, Ramirez G, Challacombe J, Anavim SA, Johnson A, Gupta M, Glass IA, Birth Defects Research Laboratory, Levy ML, Haim SB, Gonda DD, Laurent L, Hughes JF, Page DC, Blurton-Jones M, Glass CK, Coufal NG. PMID: 37582369; PMCID: PMC10529991.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro. Nat Immunol. 2023 08; 24(8):1382-1390.
Dolan MJ, Therrien M, Jereb S, Kamath T, Gazestani V, Atkeson T, Marsh SE, Goeva A, Lojek NM, Murphy S, White CM, Joung J, Liu B, Limone F, Eggan K, Hacohen N, Bernstein BE, Glass CK, Leinonen V, Blurton-Jones M, Zhang F, Epstein CB, Macosko EZ, Stevens B. PMID: 37500887; PMCID: PMC10382323.
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PubMed Mentions:
76 Fields:
Translation:
HumansCells
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APOE4/4 is linked to damaging lipid droplets in Alzheimer's microglia. bioRxiv. 2023 Jul 25.
Haney MS, Pálovics R, Munson CN, Long C, Johansson P, Yip O, Dong W, Rawat E, West E, Schlachetzki JC, Tsai A, Guldner IH, Lamichhane BS, Smith A, Schaum N, Calcuttawala K, Shin A, Wang YH, Wang C, Koutsodendris N, Serrano GE, Beach TG, Reiman EM, Glass CK, Abu-Remaileh M, Enejder A, Huang Y, Wyss-Coray T. PMID: 37546938; PMCID: PMC10401952.
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PubMed Mentions:
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Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation. EMBO Mol Med. 2023 08 07; 15(8):e16845.
Zhou E, Ge X, Nakashima H, Li R, van der Zande HJP, Liu C, Li Z, Müller C, Bracher F, Mohammed Y, de Boer JF, Kuipers F, Guigas B, Glass CK, Rensen PCN, Giera M, Wang Y. PMID: 37357756; PMCID: PMC10405065.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimals
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SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity. Nat Immunol. 2023 07; 24(7):1188-1199.
Fixsen BR, Han CZ, Zhou Y, Spann NJ, Saisan P, Shen Z, Balak C, Sakai M, Cobo I, Holtman IR, Warden AS, Ramirez G, Collier JG, Pasillas MP, Yu M, Hu R, Li B, Belhocine S, Gosselin D, Coufal NG, Ren B, Glass CK. PMID: 37322178; PMCID: PMC10307637.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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An in vivo neuroimmune organoid model to study human microglia phenotypes. Cell. 2023 05 11; 186(10):2111-2126.e20.
Schafer ST, Mansour AA, Schlachetzki JCM, Pena M, Ghassemzadeh S, Mitchell L, Mar A, Quang D, Stumpf S, Ortiz IS, Lana AJ, Baek C, Zaghal R, Glass CK, Nimmerjahn A, Gage FH. PMID: 37172564; PMCID: PMC10284271.
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PubMed Mentions:
112 Fields:
Translation:
HumansCells
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Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity. Proc Natl Acad Sci U S A. 2023 05 16; 120(20):e2210991120.
Raviram R, Raman A, Preissl S, Ning J, Wu S, Koga T, Zhang K, Brennan CW, Zhu C, Luebeck J, Van Deynze K, Han JY, Hou X, Ye Z, Mischel AK, Li YE, Fang R, Baback T, Mugford J, Han CZ, Glass CK, Barr CL, Mischel PS, Bafna V, Escoubet L, Ren B, Chen CC. PMID: 37155843; PMCID: PMC10194019.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Shp2 Deficiency in Kupffer Cells and Hepatocytes Aggravates Hepatocarcinogenesis by Recruiting Non-Kupffer Macrophages. Cell Mol Gastroenterol Hepatol. 2023; 15(6):1351-1369.
Du L, Ji Y, Xin B, Zhang J, Lu LC, Glass CK, Feng GS. PMID: 36828281; PMCID: PMC10140795.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis. Nat Commun. 2023 01 17; 14(1):251.
Arimoto KI, Miyauchi S, Troutman TD, Zhang Y, Liu M, Stoner SA, Davis AG, Fan JB, Huang YJ, Yan M, Glass CK, Zhang DE. PMID: 36646704; PMCID: PMC9842760.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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Deep learning predicts the impact of regulatory variants on cell-type-specific enhancers in the brain. Bioinform Adv. 2023; 3(1):vbad002.
Zheng A, Shen Z, Glass CK, Gymrek M. PMID: 36726730; PMCID: PMC9887460.
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PubMed Mentions:
1
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Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice. J Exp Med. 2023 02 06; 220(2).
Han RT, Vainchtein ID, Schlachetzki JCM, Cho FS, Dorman LC, Ahn E, Kim DK, Barron JJ, Nakao-Inoue H, Molofsky AB, Glass CK, Paz JT, Molofsky AV. PMID: 36520518; PMCID: PMC9757845.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's disease. Cell Stem Cell. 2022 12 01; 29(12):1637-1652.e6.
Herdy JR, Traxler L, Agarwal RK, Karbacher L, Schlachetzki JCM, Boehnke L, Zangwill D, Galasko D, Glass CK, Mertens J, Gage FH. PMID: 36459967; PMCID: PMC10093780.
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PubMed Mentions:
100 Fields:
Translation:
HumansCells
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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4. Neuron. 2023 01 18; 111(2):202-219.e7.
Gratuze M, Schlachetzki JCM, D'Oliveira Albanus R, Jain N, Novotny B, Brase L, Rodriguez L, Mansel C, Kipnis M, O'Brien S, Pasillas MP, Lee C, Manis M, Colonna M, Harari O, Glass CK, Ulrich JD, Holtzman DM. PMID: 36368315; PMCID: PMC9852006.
View in:
PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice. Elife. 2022 11 08; 11.
Abdel-Haq R, Schlachetzki JCM, Boktor JC, Cantu-Jungles TM, Thron T, Zhang M, Bostick JW, Khazaei T, Chilakala S, Morais LH, Humphrey G, Keshavarzian A, Katz JE, Thomson M, Knight R, Gradinaru V, Hamaker BR, Glass CK, Mazmanian SK. PMID: 36346385; PMCID: PMC9668333.
View in:
PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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Microglia states and nomenclature: A field at its crossroads. Neuron. 2022 11 02; 110(21):3458-3483.
Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, Boddeke E, Brites D, Brône B, Brown GC, Butovsky O, Carson MJ, Castellano B, Colonna M, Cowley SA, Cunningham C, Davalos D, De Jager PL, de Strooper B, Denes A, Eggen BJL, Eyo U, Galea E, Garel S, Ginhoux F, Glass CK, Gokce O, Gomez-Nicola D, González B, Gordon S, Graeber MB, Greenhalgh AD, Gressens P, Greter M, Gutmann DH, Haass C, Heneka MT, Heppner FL, Hong S, Hume DA, Jung S, Kettenmann H, Kipnis J, Koyama R, Lemke G, Lynch M, Majewska A, Malcangio M, Malm T, Mancuso R, Masuda T, Matteoli M, McColl BW, Miron VE, Molofsky AV, Monje M, Mracsko E, Nadjar A, Neher JJ, Neniskyte U, Neumann H, Noda M, Peng B, Peri F, Perry VH, Popovich PG, Pridans C, Priller J, Prinz M, Ragozzino D, Ransohoff RM, Salter MW, Schaefer A, Schafer DP, Schwartz M, Simons M, Smith CJ, Streit WJ, Tay TL, Tsai LH, Verkhratsky A, von Bernhardi R, Wake H, Wittamer V, Wolf SA, Wu LJ, Wyss-Coray T. PMID: 36327895; PMCID: PMC9999291.
View in:
PubMed Mentions:
869 Fields:
Translation:
Cells
-
The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands. Immunity. 2022 11 08; 55(11):2006-2026.e6.
Czimmerer Z, Halasz L, Daniel B, Varga Z, Bene K, Domokos A, Hoeksema M, Shen Z, Berger WK, Cseh T, Jambrovics K, Kolostyak Z, Fenyvesi F, Varadi J, Poliska S, Hajas G, Szatmari I, Glass CK, Bacsi A, Nagy L. PMID: 36323312; PMCID: PMC9649892.
View in:
PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Human microglia phenotypes in the brain associated with HIV infection. Curr Opin Neurobiol. 2022 12; 77:102637.
Schlachetzki JCM, Zhou Y, Glass CK. PMID: 36194988.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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The TBK1/IKKε inhibitor amlexanox improves dyslipidemia and prevents atherosclerosis. JCI Insight. 2022 09 08; 7(17).
Zhao P, Sun X, Liao Z, Yu H, Li D, Shen Z, Glass CK, Witztum JL, Saltiel AR. PMID: 35917178; PMCID: PMC9536260.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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CSF1R-Mediated Myeloid Cell Depletion Prolongs Lifespan But Aggravates Distinct Motor Symptoms in a Model of Multiple System Atrophy. J Neurosci. 2022 10 05; 42(40):7673-7688.
Battis K, Florio JB, Mante M, Lana A, Naumann I, Gauer C, Lambrecht V, Müller SJ, Cobo I, Fixsen B, Kim HY, Masliah E, Glass CK, Schlachetzki JCM, Rissman RA, Winkler J, Hoffmann A. PMID: 36333098; PMCID: PMC9546481.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Shared Mechanisms between Cardiovascular Disease and NAFLD. Semin Liver Dis. 2022 11; 42(4):455-464.
Huang DQ, Downes M, Evans RM, Witztum JL, Glass CK, Loomba R. PMID: 36008083; PMCID: PMC9828940.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's disease. Cell Metab. 2022 09 06; 34(9):1248-1263.e6.
Traxler L, Herdy JR, Stefanoni D, Eichhorner S, Pelucchi S, Szücs A, Santagostino A, Kim Y, Agarwal RK, Schlachetzki JCM, Glass CK, Lagerwall J, Galasko D, Gage FH, D'Alessandro A, Mertens J. PMID: 35987203; PMCID: PMC9458870.
View in:
PubMed Mentions:
88 Fields:
Translation:
HumansCells
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DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages. Immunity. 2022 08 09; 55(8):1386-1401.e10.
Cobo I, Tanaka TN, Chandra Mangalhara K, Lana A, Yeang C, Han C, Schlachetzki J, Challcombe J, Fixsen BR, Sakai M, Li RZ, Fields H, Mokry M, Tsai RG, Bejar R, Prange K, de Winther M, Shadel GS, Glass CK. PMID: 35931086; PMCID: PMC9718507.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Author Correction: Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. Nat Chem Biol. 2022 May; 18(5):575.
Weiss RJ, Spahn PN, Chiang AWT, Liu Q, Li J, Hamill KM, Rother S, Clausen TM, Hoeksema MA, Timm BM, Godula K, Glass CK, Tor Y, Gordts PLSM, Lewis NE, Esko JD. PMID: 35354934.
View in:
PubMed Mentions: Fields:
-
Somatic mosaicism reveals clonal distributions of neocortical development. Nature. 2022 04; 604(7907):689-696.
Breuss MW, Yang X, Schlachetzki JCM, Antaki D, Lana AJ, Xu X, Chung C, Chai G, Stanley V, Song Q, Newmeyer TF, Nguyen A, O'Brien S, Hoeksema MA, Cao B, Nott A, McEvoy-Venneri J, Pasillas MP, Barton ST, Copeland BR, Nahas S, Van Der Kraan L, Ding Y, NIMH Brain Somatic Mosaicism Network, Glass CK, Gleeson JG. PMID: 35444276; PMCID: PMC9436791.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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The Lung Microenvironment Instructs Gene Transcription in Neonatal and Adult Alveolar Macrophages. J Immunol. 2022 04 15; 208(8):1947-1959.
Honda A, Hoeksema MA, Sakai M, Lund SJ, Lakhdari O, Butcher LD, Rambaldo TC, Sekiya NM, Nasamran CA, Fisch KM, Sajti E, Glass CK, Prince LS. PMID: 35354612; PMCID: PMC9012679.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response. Cell Rep. 2022 03 08; 38(10):110489.
Cobo I, Cheng A, Murillo-Saich J, Coras R, Torres A, Abe Y, Lana AJ, Schlachetzki J, Liu-Bryan R, Terkeltaub R, Sanchez-Lopez E, Glass CK, Guma M. PMID: 35263587; PMCID: PMC8989403.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Systemic Influences of Mammary Cancer on Monocytes in Mice. Cancers (Basel). 2022 Feb 07; 14(3).
Robinson A, Burgess M, Webb S, Louwe PA, Ouyang Z, Skola D, Han CZ, Batada NN, González-Huici V, Cassetta L, Glass CK, Jenkins SJ, Pollard JW. PMID: 35159100; PMCID: PMC8834227.
View in:
PubMed Mentions:
7
-
Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs. Elife. 2022 01 20; 11.
Shen Z, Li RZ, Prohaska TA, Hoeksema MA, Spann NJ, Tao J, Fonseca GJ, Le T, Stolze LK, Sakai M, Romanoski CE, Glass CK. PMID: 35049498; PMCID: PMC8809895.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Clonal hematopoiesis driven by DNMT3A and TET2 mutations: role in monocyte and macrophage biology and atherosclerotic cardiovascular disease. Curr Opin Hematol. 2022 01 01; 29(1):1-7.
Cobo I, Tanaka T, Glass CK, Yeang C. PMID: 34654019; PMCID: PMC8639635.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Exploiting dynamic enhancer landscapes to decode macrophage and microglia phenotypes in health and disease. Mol Cell. 2021 10 07; 81(19):3888-3903.
Troutman TD, Kofman E, Glass CK. PMID: 34464593; PMCID: PMC8500948.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Heterogeneity of HSCs in a Mouse Model of NASH. Hepatology. 2021 08; 74(2):667-685.
Rosenthal SB, Liu X, Ganguly S, Dhar D, Pasillas MP, Ricciardelli E, Li RZ, Troutman TD, Kisseleva T, Glass CK, Brenner DA. PMID: 33550587; PMCID: PMC8346581.
View in:
PubMed Mentions:
69 Fields:
Translation:
HumansAnimalsCells
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A Cdk4/6-dependent phosphorylation gradient regulates the early to late G1 phase transition. Sci Rep. 2021 07 19; 11(1):14736.
Kaulich M, Link VM, Lapek JD, Lee YJ, Glass CK, Gonzalez DJ, Dowdy SF. PMID: 34282211; PMCID: PMC8290049.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells. NAR Genom Bioinform. 2021 Sep; 3(3):lqab061.
Shamie I, Duttke SH, Karottki KJC, Han CZ, Hansen AH, Hefzi H, Xiong K, Li S, Roth SJ, Tao J, Lee GM, Glass CK, Kildegaard HF, Benner C, Lewis NE. PMID: 34268494; PMCID: PMC8276764.
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PubMed Mentions:
12 Fields:
-
Diet-regulated production of PDGFcc by macrophages controls energy storage. Science. 2021 07 02; 373(6550).
Cox N, Crozet L, Holtman IR, Loyher PL, Lazarov T, White JB, Mass E, Stanley ER, Elemento O, Glass CK, Geissmann F. PMID: 34210853; PMCID: PMC9558257.
View in:
PubMed Mentions:
75 Fields:
Translation:
AnimalsCells
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Mechanisms underlying divergent responses of genetically distinct macrophages to IL-4. Sci Adv. 2021 06; 7(25).
Hoeksema MA, Shen Z, Holtman IR, Zheng A, Spann NJ, Cobo I, Gymrek M, Glass CK. PMID: 34134993; PMCID: PMC8208725.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients. Cell Stem Cell. 2021 09 02; 28(9):1533-1548.e6.
Mertens J, Herdy JR, Traxler L, Schafer ST, Schlachetzki JCM, Böhnke L, Reid DA, Lee H, Zangwill D, Fernandes DP, Agarwal RK, Lucciola R, Zhou-Yang L, Karbacher L, Edenhofer F, Stern S, Horvath S, Paquola ACM, Glass CK, Yuan SH, Ku M, Szücs A, Goldstein LSB, Galasko D, Gage FH. PMID: 33910058; PMCID: PMC8423435.
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PubMed Mentions:
123 Fields:
Translation:
HumansCells
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PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response. Proc Natl Acad Sci U S A. 2021 04 20; 118(16).
Li J, Kaneda MM, Ma J, Li M, Shepard RM, Patel K, Koga T, Sarver A, Furnari F, Xu B, Dhawan S, Ning J, Zhu H, Wu A, You G, Jiang T, Venteicher AS, Rich JN, Glass CK, Varner JA, Chen CC. PMID: 33846242; PMCID: PMC8072253.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. Nat Chem Biol. 2021 06; 17(6):684-692.
Weiss RJ, Spahn PN, Chiang AWT, Liu Q, Li J, Hamill KM, Rother S, Clausen TM, Hoeksema MA, Timm BM, Godula K, Glass CK, Tor Y, Gordts PLSM, Lewis NE, Esko JD. PMID: 33846619; PMCID: PMC8159865.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons. Science. 2021 04 02; 372(6537):91-94.
Reid DA, Reed PJ, Schlachetzki JCM, Nitulescu II, Chou G, Tsui EC, Jones JR, Chandran S, Lu AT, McClain CA, Ooi JH, Wang TW, Lana AJ, Linker SB, Ricciardulli AS, Lau S, Schafer ST, Horvath S, Dixon JR, Hah N, Glass CK, Gage FH. PMID: 33795458; PMCID: PMC9179101.
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PubMed Mentions:
62 Fields:
-
Purification of mouse hepatic non-parenchymal cells or nuclei for use in ChIP-seq and other next-generation sequencing approaches. STAR Protoc. 2021 03 19; 2(1):100363.
Troutman TD, Bennett H, Sakai M, Seidman JS, Heinz S, Glass CK. PMID: 33748781; PMCID: PMC7960533.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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FOXO1 constrains activation and regulates senescence in CD8 T cells. Cell Rep. 2021 01 26; 34(4):108674.
Delpoux A, Marcel N, Hess Michelini R, Katayama CD, Allison KA, Glass CK, Quiñones-Parra SM, Murre C, Loh L, Kedzierska K, Lappas M, Hedrick SM, Doedens AL. PMID: 33503413.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
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Epigenetic Regulation of Kupffer Cell Function in Health and Disease. Front Immunol. 2020; 11:609618.
Bennett H, Troutman TD, Sakai M, Glass CK. PMID: 33574817; PMCID: PMC7870864.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Nuclei isolation of multiple brain cell types for omics interrogation. Nat Protoc. 2021 03; 16(3):1629-1646.
Nott A, Schlachetzki JCM, Fixsen BR, Glass CK. PMID: 33495627; PMCID: PMC7969463.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Monocyte Regulation in Homeostasis and Malignancy. Trends Immunol. 2021 02; 42(2):104-119.
Robinson A, Han CZ, Glass CK, Pollard JW. PMID: 33446416; PMCID: PMC7877795.
View in:
PubMed Mentions:
91 Fields:
Translation:
HumansCells
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Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics. Circ Res. 2020 11 06; 127(11):1437-1455.
Depuydt MAC, Prange KHM, Slenders L, Örd T, Elbersen D, Boltjes A, de Jager SCA, Asselbergs FW, de Borst GJ, Aavik E, Lönnberg T, Lutgens E, Glass CK, den Ruijter HM, Kaikkonen MU, Bot I, Slütter B, van der Laan SW, Yla-Herttuala S, Mokry M, Kuiper J, de Winther MPJ, Pasterkamp G. PMID: 32981416; PMCID: PMC7641189.
View in:
PubMed Mentions:
299 Fields:
Translation:
HumansAnimalsCells
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MAGGIE: leveraging genetic variation to identify DNA sequence motifs mediating transcription factor binding and function. Bioinformatics. 2020 07 01; 36(Suppl_1):i84-i92.
Shen Z, Hoeksema MA, Ouyang Z, Benner C, Glass CK. PMID: 32657363; PMCID: PMC7355228.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
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Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance. Nat Cell Biol. 2020 06; 22(6):701-715.
Bi M, Zhang Z, Jiang YZ, Xue P, Wang H, Lai Z, Fu X, De Angelis C, Gong Y, Gao Z, Ruan J, Jin VX, Marangoni E, Montaudon E, Glass CK, Li W, Huang TH, Shao ZM, Schiff R, Chen L, Liu Z. PMID: 32424275; PMCID: PMC7737911.
View in:
PubMed Mentions:
86 Fields:
Translation:
HumansAnimalsCells
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Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis. Immunity. 2020 06 16; 52(6):1057-1074.e7.
Seidman JS, Troutman TD, Sakai M, Gola A, Spann NJ, Bennett H, Bruni CM, Ouyang Z, Li RZ, Sun X, Vu BT, Pasillas MP, Ego KM, Gosselin D, Link VM, Chong LW, Evans RM, Thompson BM, McDonald JG, Hosseini M, Witztum JL, Germain RN, Glass CK. PMID: 32362324; PMCID: PMC7305990.
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PubMed Mentions:
227 Fields:
Translation:
AnimalsCells
-
ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis. Proc Natl Acad Sci U S A. 2020 04 28; 117(17):9311-9317.
Weiss RJ, Spahn PN, Toledo AG, Chiang AWT, Kellman BP, Li J, Benner C, Glass CK, Gordts PLSM, Lewis NE, Esko JD. PMID: 32277030; PMCID: PMC7196839.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Author Correction: A monocyte gene expression signature in the early clinical course of Parkinson's disease. Sci Rep. 2020 Apr 07; 10(1):6261.
Schlachetzki JCM, Prots I, Tao J, Chun HB, Saijo K, Gosselin D, Winner B, Glass CK, Winkler J. PMID: 32253373; PMCID: PMC7136204.
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PubMed Mentions:
2 Fields:
-
Chronic Peripheral Inflammation Causes a Region-Specific Myeloid Response in the Central Nervous System. Cell Rep. 2020 03 24; 30(12):4082-4095.e6.
Süß P, Hoffmann A, Rothe T, Ouyang Z, Baum W, Staszewski O, Schett G, Prinz M, Krönke G, Glass CK, Winkler J, Schlachetzki JCM. PMID: 32209470.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells. EMBO J. 2020 04 01; 39(7):e103949.
Higashijima Y, Matsui Y, Shimamura T, Nakaki R, Nagai N, Tsutsumi S, Abe Y, Link VM, Osaka M, Yoshida M, Watanabe R, Tanaka T, Taguchi A, Miura M, Ruan X, Li G, Inoue T, Nangaku M, Kimura H, Furukawa T, Aburatani H, Wada Y, Ruan Y, Glass CK, Kanki Y. PMID: 32125007; PMCID: PMC7110136.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. JCI Insight. 2020 02 13; 5(3).
Xu J, Ma HY, Liu X, Rosenthal S, Baglieri J, McCubbin R, Sun M, Koyama Y, Geoffroy CG, Saijo K, Shang L, Nishio T, Maricic I, Kreifeldt M, Kusumanchi P, Roberts A, Zheng B, Kumar V, Zengler K, Pizzo DP, Hosseini M, Contet C, Glass CK, Liangpunsakul S, Tsukamoto H, Gao B, Karin M, Brenner DA, Koob GF, Kisseleva T. PMID: 32051339; PMCID: PMC7098802.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Macrophage Syk-PI3Kγ Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk-PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression. Mol Cancer Ther. 2020 03; 19(3):755-764.
Joshi S, Liu KX, Zulcic M, Singh AR, Skola D, Glass CK, Sanders PD, Sharabi AB, Pham TV, Tamayo P, Shiang D, Dinh HQ, Hedrick CC, Morales GA, Garlich JR, Durden DL. PMID: 31974273; PMCID: PMC7450492.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution. Gastroenterology. 2020 05; 158(6):1728-1744.e14.
Liu X, Xu J, Rosenthal S, Zhang LJ, McCubbin R, Meshgin N, Shang L, Koyama Y, Ma HY, Sharma S, Heinz S, Glass CK, Benner C, Brenner DA, Kisseleva T. PMID: 31982409; PMCID: PMC7252905.
View in:
PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsCells
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Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung. Nat Immunol. 2020 02; 21(2):221-231.
Sajti E, Link VM, Ouyang Z, Spann NJ, Westin E, Romanoski CE, Fonseca GJ, Prince LS, Glass CK. PMID: 31959980; PMCID: PMC7667722.
View in:
PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
-
The coming of age of Langerhans cell histiocytosis. Nat Immunol. 2020 01; 21(1):1-7.
Allen CE, Beverley PCL, Collin M, Diamond EL, Egeler RM, Ginhoux F, Glass C, Minkov M, Rollins BJ, van Halteren A. PMID: 31831887.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Cx3cr1-deficient microglia exhibit a premature aging transcriptome. Life Sci Alliance. 2019 12; 2(6).
Gyoneva S, Hosur R, Gosselin D, Zhang B, Ouyang Z, Cotleur AC, Peterson M, Allaire N, Challa R, Cullen P, Roberts C, Miao K, Reynolds TL, Glass CK, Burkly L, Ransohoff RM. PMID: 31792059; PMCID: PMC6892408.
View in:
PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
-
Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. Cell Metab. 2020 01 07; 31(1):189-206.e8.
Sun X, Seidman JS, Zhao P, Troutman TD, Spann NJ, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida JA, Kisseleva T, Brenner DA, Downes M, Evans RM, Saltiel AR, Tsimikas S, Glass CK, Witztum JL. PMID: 31761566; PMCID: PMC7028360.
View in:
PubMed Mentions:
98 Fields:
Translation:
HumansAnimalsCells
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Brain cell type-specific enhancer-promoter interactome maps and disease-risk association. Science. 2019 11 29; 366(6469):1134-1139.
Nott A, Holtman IR, Coufal NG, Schlachetzki JCM, Yu M, Hu R, Han CZ, Pena M, Xiao J, Wu Y, Keulen Z, Pasillas MP, O'Connor C, Nickl CK, Schafer ST, Shen Z, Rissman RA, Brewer JB, Gosselin D, Gonda DD, Levy ML, Rosenfeld MG, McVicker G, Gage FH, Ren B, Glass CK. PMID: 31727856; PMCID: PMC7028213.
View in:
PubMed Mentions:
391 Fields:
Translation:
HumansCells
-
Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity. Immunity. 2019 10 15; 51(4):655-670.e8.
Sakai M, Troutman TD, Seidman JS, Ouyang Z, Spann NJ, Abe Y, Ego KM, Bruni CM, Deng Z, Schlachetzki JCM, Nott A, Bennett H, Chang J, Vu BT, Pasillas MP, Link VM, Texari L, Heinz S, Thompson BM, McDonald JG, Geissmann F, Glass CK. PMID: 31587991; PMCID: PMC6800814.
View in:
PubMed Mentions:
220 Fields:
Translation:
AnimalsCells
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Transcriptional and epigenetic regulation of macrophages in atherosclerosis. Nat Rev Cardiol. 2020 04; 17(4):216-228.
Kuznetsova T, Prange KHM, Glass CK, de Winther MPJ. PMID: 31578516; PMCID: PMC7770754.
View in:
PubMed Mentions:
195 Fields:
Translation:
Cells
-
PHLPP1 counter-regulates STAT1-mediated inflammatory signaling. Elife. 2019 08 13; 8.
Cohen Katsenelson K, Stender JD, Kawashima AT, Lordén G, Uchiyama S, Nizet V, Glass CK, Newton AC. PMID: 31408005; PMCID: PMC6692130.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. Neuron. 2019 09 25; 103(6):1016-1033.e10.
Hasselmann J, Coburn MA, England W, Figueroa Velez DX, Kiani Shabestari S, Tu CH, McQuade A, Kolahdouzan M, Echeverria K, Claes C, Nakayama T, Azevedo R, Coufal NG, Han CZ, Cummings BJ, Davtyan H, Glass CK, Healy LM, Gandhi SP, Spitale RC, Blurton-Jones M. PMID: 31375314; PMCID: PMC7138101.
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PubMed Mentions:
195 Fields:
Translation:
HumansAnimalsCells
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Leducq Epigenetics of Atherosclerosis Network. Circ Res. 2019 06 07; 124(12):1697-1700.
de Winther MPJ, Glass CK. PMID: 31170047.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer. Mol Cancer Ther. 2019 06; 18(6):1036-1044.
Joshi S, Singh AR, Liu KX, Pham TV, Zulcic M, Skola D, Chun HB, Glass CK, Morales GA, Garlich JR, Durden DL. PMID: 31018997; PMCID: PMC6893301.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophages. Nat Commun. 2019 01 24; 10(1):414.
Fonseca GJ, Tao J, Westin EM, Duttke SH, Spann NJ, Strid T, Shen Z, Stender JD, Sakai M, Link VM, Benner C, Glass CK. PMID: 30679424; PMCID: PMC6345992.
View in:
PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice. Transl Psychiatry. 2019 01 17; 9(1):24.
Moore SM, Seidman JS, Ellegood J, Gao R, Savchenko A, Troutman TD, Abe Y, Stender J, Lee D, Wang S, Voytek B, Lerch JP, Suh H, Glass CK, Muotri AR. PMID: 30655503; PMCID: PMC6336863.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons. Nat Neurosci. 2019 02; 22(2):243-255.
Schafer ST, Paquola ACM, Stern S, Gosselin D, Ku M, Pena M, Kuret TJM, Liyanage M, Mansour AA, Jaeger BN, Marchetto MC, Glass CK, Mertens J, Gage FH. PMID: 30617258; PMCID: PMC6402576.
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PubMed Mentions:
146 Fields:
Translation:
HumansCells
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A longitudinal systems immunologic investigation of acute Zika virus infection in an individual infected while traveling to Caracas, Venezuela. PLoS Negl Trop Dis. 2018 12; 12(12):e0007053.
Carlin AF, Wen J, Vizcarra EA, McCauley M, Chaillon A, Akrami K, Kim C, Ngono AE, Lara-Marquez ML, Smith DM, Glass CK, Schooley RT, Benner C, Shresta S. PMID: 30596671; PMCID: PMC6329527.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity. Cell Metab. 2019 02 05; 29(2):457-474.e5.
Ying W, Lee YS, Dong Y, Seidman JS, Yang M, Isaac R, Seo JB, Yang BH, Wollam J, Riopel M, McNelis J, Glass CK, Olefsky JM, Fu W. PMID: 30595478; PMCID: PMC6701710.
View in:
PubMed Mentions:
147 Fields:
Translation:
AnimalsCells
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Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge. Nat Commun. 2018 12 06; 9(1):5206.
Shemer A, Grozovski J, Tay TL, Tao J, Volaski A, Süß P, Ardura-Fabregat A, Gross-Vered M, Kim JS, David E, Chappell-Maor L, Thielecke L, Glass CK, Cornils K, Prinz M, Jung S. PMID: 30523248; PMCID: PMC6284018.
View in:
PubMed Mentions:
134 Fields:
Translation:
HumansAnimalsCells
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Microbiome-microglia connections via the gut-brain axis. J Exp Med. 2019 01 07; 216(1):41-59.
Abdel-Haq R, Schlachetzki JCM, Glass CK, Mazmanian SK. PMID: 30385457; PMCID: PMC6314531.
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PubMed Mentions:
246 Fields:
Translation:
HumansAnimalsCells
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Nature and nurture of tissue-specific macrophage phenotypes. Atherosclerosis. 2019 02; 281:159-167.
Hoeksema MA, Glass CK. PMID: 30343819; PMCID: PMC6399046.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages. Proc Natl Acad Sci U S A. 2018 09 25; 115(39):E9172-E9181.
Carlin AF, Vizcarra EA, Branche E, Viramontes KM, Suarez-Amaran L, Ley K, Heinz S, Benner C, Shresta S, Glass CK. PMID: 30206152; PMCID: PMC6166801.
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PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. 2018 09; 561(7724):E43.
Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. PMID: 30013121.
View in:
PubMed Mentions:
2 Fields:
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MMARGE: Motif Mutation Analysis for Regulatory Genomic Elements. Nucleic Acids Res. 2018 08 21; 46(14):7006-7021.
Link VM, Romanoski CE, Metzler D, Glass CK. PMID: 29893919; PMCID: PMC6101580.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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A monocyte gene expression signature in the early clinical course of Parkinson's disease. Sci Rep. 2018 Jul 17; 8(1):10757.
Schlachetzki JCM, Prots I, Tao J, Chun HB, Saijo K, Gosselin D, Winner B, Glass CK, Winkler J. PMID: 30018301; PMCID: PMC6050266.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. 2018 06; 558(7709):301-306.
Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. PMID: 29875409; PMCID: PMC6033669.
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PubMed Mentions:
264 Fields:
Translation:
AnimalsCells
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Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile. Cell Rep. 2018 05 29; 23(9):2550-2558.
Kim Y, Zheng X, Ansari Z, Bunnell MC, Herdy JR, Traxler L, Lee H, Paquola ACM, Blithikioti C, Ku M, Schlachetzki JCM, Winkler J, Edenhofer F, Glass CK, Paucar AA, Jaeger BN, Pham S, Boyer L, Campbell BC, Hunter T, Mertens J, Gage FH. PMID: 29847787; PMCID: PMC6478017.
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PubMed Mentions:
70 Fields:
Translation:
HumansCells
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Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function. Cell. 2018 06 14; 173(7):1796-1809.e17.
Link VM, Duttke SH, Chun HB, Holtman IR, Westin E, Hoeksema MA, Abe Y, Skola D, Romanoski CE, Tao J, Fonseca GJ, Troutman TD, Spann NJ, Strid T, Sakai M, Yu M, Hu R, Fang R, Metzler D, Ren B, Glass CK. PMID: 29779944; PMCID: PMC6003872.
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PubMed Mentions:
119 Fields:
Translation:
AnimalsCells
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NDF, a nucleosome-destabilizing factor that facilitates transcription through nucleosomes. Genes Dev. 2018 05 01; 32(9-10):682-694.
Fei J, Ishii H, Hoeksema MA, Meitinger F, Kassavetis GA, Glass CK, Ren B, Kadonaga JT. PMID: 29759984; PMCID: PMC6004073.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages. Proc Natl Acad Sci U S A. 2018 05 15; 115(20):E4680-E4689.
Muse ED, Yu S, Edillor CR, Tao J, Spann NJ, Troutman TD, Seidman JS, Henke A, Roland JT, Ozeki KA, Thompson BM, McDonald JG, Bahadorani J, Tsimikas S, Grossman TR, Tremblay MS, Glass CK. PMID: 29632203; PMCID: PMC5960280.
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PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
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Immune memory in the brain. Nature. 2018 04; 556(7701):312-313.
Nott A, Glass CK. PMID: 29662132.
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PubMed Mentions:
5 Fields:
-
The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Mol Cell. 2018 03 01; 69(5):915.
Neal S, Jaeger PA, Duttke SH, Benner C, Glass CK, Ideker T, Hampton RY. PMID: 29499140.
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PubMed Mentions:
14 Fields:
-
Massively Parallel Sequencing of Peritoneal and Splenic B Cell Repertoires Highlights Unique Properties of B-1 Cell Antibodies. J Immunol. 2018 03 01; 200(5):1702-1717.
Prohaska TA, Que X, Diehl CJ, Hendrikx S, Chang MW, Jepsen K, Glass CK, Benner C, Witztum JL. PMID: 29378911; PMCID: PMC5821571.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):E244-E252.
Wang J, Saijo K, Skola D, Jin C, Ma Q, Merkurjev D, Glass CK, Rosenfeld MG. PMID: 29263096; PMCID: PMC5777077.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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An IRF-3-, IRF-5-, and IRF-7-Independent Pathway of Dengue Viral Resistance Utilizes IRF-1 to Stimulate Type I and II Interferon Responses. Cell Rep. 2017 Nov 07; 21(6):1600-1612.
Carlin AF, Plummer EM, Vizcarra EA, Sheets N, Joo Y, Tang W, Day J, Greenbaum J, Glass CK, Diamond MS, Shresta S. PMID: 29117564; PMCID: PMC5696617.
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PubMed Mentions:
45 Fields:
Translation:
AnimalsCells
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Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine. Nat Med. 2017 Nov; 23(11):1309-1318.
Pirzgalska RM, Seixas E, Seidman JS, Link VM, Sánchez NM, Mahú I, Mendes R, Gres V, Kubasova N, Morris I, Arús BA, Larabee CM, Vasques M, Tortosa F, Sousa AL, Anandan S, Tranfield E, Hahn MK, Iannacone M, Spann NJ, Glass CK, Domingos AI. PMID: 29035364; PMCID: PMC7104364.
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PubMed Mentions:
266 Fields:
Translation:
AnimalsCells
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Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling. Nat Commun. 2017 09 29; 8(1):754.
Rahnamoun H, Lu H, Duttke SH, Benner C, Glass CK, Lauberth SM. PMID: 28963538; PMCID: PMC5622043.
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PubMed Mentions:
66 Fields:
Translation:
HumansCells
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Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations. J Exp Med. 2017 Nov 06; 214(11):3331-3346.
Lopez-Ramirez MA, Fonseca G, Zeineddine HA, Girard R, Moore T, Pham A, Cao Y, Shenkar R, de Kreuk BJ, Lagarrigue F, Lawler J, Glass CK, Awad IA, Ginsberg MH. PMID: 28970240; PMCID: PMC5679163.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Transcriptional control of microglia phenotypes in health and disease. J Clin Invest. 2017 Sep 01; 127(9):3220-3229.
Holtman IR, Skola D, Glass CK. PMID: 28758903; PMCID: PMC5669536.
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PubMed Mentions:
122 Fields:
Translation:
HumansAnimalsCells
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Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells. Elife. 2017 06 06; 6.
Hogan NT, Whalen MB, Stolze LK, Hadeli NK, Lam MT, Springstead JR, Glass CK, Romanoski CE. PMID: 28585919; PMCID: PMC5461113.
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PubMed Mentions:
63 Fields:
Translation:
HumansCells
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An environment-dependent transcriptional network specifies human microglia identity. Science. 2017 06 23; 356(6344).
Gosselin D, Skola D, Coufal NG, Holtman IR, Schlachetzki JCM, Sajti E, Jaeger BN, O'Connor C, Fitzpatrick C, Pasillas MP, Pena M, Adair A, Gonda DD, Levy ML, Ransohoff RM, Gage FH, Glass CK. PMID: 28546318; PMCID: PMC5858585.
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PubMed Mentions:
613 Fields:
Translation:
HumansAnimalsCells
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Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity. Immunity. 2017 05 16; 46(5):714-729.
Phan AT, Goldrath AW, Glass CK. PMID: 28514673; PMCID: PMC5505665.
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PubMed Mentions:
165 Fields:
Translation:
HumansAnimalsCells
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Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells. Mol Cell. 2017 Mar 16; 65(6):1122-1135.e5.
Stender JD, Nwachukwu JC, Kastrati I, Kim Y, Strid T, Yakir M, Srinivasan S, Nowak J, Izard T, Rangarajan ES, Carlson KE, Katzenellenbogen JA, Yao XQ, Grant BJ, Leong HS, Lin CY, Frasor J, Nettles KW, Glass CK. PMID: 28306507; PMCID: PMC5546241.
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PubMed Mentions:
60 Fields:
Translation:
HumansCells
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Loss of CMAH during Human Evolution Primed the Monocyte-Macrophage Lineage toward a More Inflammatory and Phagocytic State. J Immunol. 2017 03 15; 198(6):2366-2373.
Okerblom JJ, Schwarz F, Olson J, Fletes W, Ali SR, Martin PT, Glass CK, Nizet V, Varki A. PMID: 28148732; PMCID: PMC5340615.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism. Cell Metab. 2017 02 07; 25(2):412-427.
Oishi Y, Spann NJ, Link VM, Muse ED, Strid T, Edillor C, Kolar MJ, Matsuzaka T, Hayakawa S, Tao J, Kaikkonen MU, Carlin AF, Lam MT, Manabe I, Shimano H, Saghatelian A, Glass CK. PMID: 28041958; PMCID: PMC5568699.
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PubMed Mentions:
197 Fields:
Translation:
AnimalsCells
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Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function. Immunity. 2016 11 15; 45(5):975-987.
Thomas GD, Hanna RN, Vasudevan NT, Hamers AA, Romanoski CE, McArdle S, Ross KD, Blatchley A, Yoakum D, Hamilton BA, Mikulski Z, Jain MK, Glass CK, Hedrick CC. PMID: 27814941; PMCID: PMC5694686.
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PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
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Genome-Wide Approaches to Defining Macrophage Identity and Function. Microbiol Spectr. 2016 10; 4(5).
Fonseca GJ, Seidman JS, Glass CK. PMID: 28087927; PMCID: PMC5240536.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages. Elife. 2016 07 27; 5.
Eichenfield DZ, Troutman TD, Link VM, Lam MT, Cho H, Gosselin D, Spann NJ, Lesch HP, Tao J, Muto J, Gallo RL, Evans RM, Glass CK. PMID: 27462873; PMCID: PMC4963201.
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PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016 07 18; 214(2):155-66.
Meitinger F, Anzola JV, Kaulich M, Richardson A, Stender JD, Benner C, Glass CK, Dowdy SF, Desai A, Shiau AK, Oegema K. PMID: 27432897; PMCID: PMC4949453.
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PubMed Mentions:
131 Fields:
Translation:
HumansCells
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Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells. Elife. 2016 07 04; 5.
Allison KA, Sajti E, Collier JG, Gosselin D, Troutman TD, Stone EL, Hedrick SM, Glass CK. PMID: 27376549; PMCID: PMC4931909.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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Dissociated sterol-based liver X receptor agonists as therapeutics for chronic inflammatory diseases. FASEB J. 2016 07; 30(7):2570-9.
Yu S, Li S, Henke A, Muse ED, Cheng B, Welzel G, Chatterjee AK, Wang D, Roland J, Glass CK, Tremblay M. PMID: 27025962; PMCID: PMC4904286.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Molecular control of activation and priming in macrophages. Nat Immunol. 2016 Jan; 17(1):26-33.
Glass CK, Natoli G. PMID: 26681459; PMCID: PMC4795476.
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PubMed Mentions:
264 Fields:
Translation:
HumansAnimalsCells
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Mechanisms Underlying the Selection and Function of Macrophage-Specific Enhancers. Cold Spring Harb Symp Quant Biol. 2015; 80:213-21.
Link VM, Gosselin D, Glass CK. PMID: 26582787; PMCID: PMC4936825.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Perspectives on Unidirectional versus Divergent Transcription. Mol Cell. 2015 Nov 05; 60(3):348-9.
Duttke SH, Lacadie SA, Ibrahim MM, Glass CK, Corcoran DL, Benner C, Heinz S, Kadonaga JT, Ohler U. PMID: 26545075; PMCID: PMC4643650.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation. Nat Immunol. 2015 Dec; 16(12):1228-34.
Shaked I, Hanna RN, Shaked H, Chodaczek G, Nowyhed HN, Tweet G, Tacke R, Basat AB, Mikulski Z, Togher S, Miller J, Blatchley A, Salek-Ardakani S, Darvas M, Kaikkonen MU, Thomas GD, Lai-Wing-Sun S, Rezk A, Bar-Or A, Glass CK, Bandukwala H, Hedrick CC. PMID: 26523867; PMCID: PMC4833087.
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PubMed Mentions:
72 Fields:
Translation:
HumansAnimalsCells
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Exploiting genomics and natural genetic variation to decode macrophage enhancers. Trends Immunol. 2015 Sep; 36(9):507-18.
Romanoski CE, Link VM, Heinz S, Glass CK. PMID: 26298065; PMCID: PMC4548828.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Daniel Steinberg, 1922-2015. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):9791-2.
Glass CK, Witztum JL. PMID: 26209653; PMCID: PMC4538637.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Transcription factor ISL1 is essential for pacemaker development and function. J Clin Invest. 2015 Aug 03; 125(8):3256-68.
Liang X, Zhang Q, Cattaneo P, Zhuang S, Gong X, Spann NJ, Jiang C, Cao X, Zhao X, Zhang X, Bu L, Wang G, Chen HS, Zhuang T, Yan J, Geng P, Luo L, Banerjee I, Chen Y, Glass CK, Zambon AC, Chen J, Sun Y, Evans SM. PMID: 26193633; PMCID: PMC4563735.
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PubMed Mentions:
79 Fields:
Translation:
AnimalsCells
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The choreography of neuroinflammation in Huntington's disease. Trends Immunol. 2015 Jun; 36(6):364-73.
Crotti A, Glass CK. PMID: 26001312; PMCID: PMC4786070.
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PubMed Mentions:
122 Fields:
Translation:
HumansAnimalsCells
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Siglec receptors impact mammalian lifespan by modulating oxidative stress. Elife. 2015 Apr 07; 4.
Schwarz F, Pearce OM, Wang X, Samraj AN, Läubli H, Garcia JO, Lin H, Fu X, Garcia-Bingman A, Secrest P, Romanoski CE, Heyser C, Glass CK, Hazen SL, Varki N, Varki A, Gagneux P. PMID: 25846707; PMCID: PMC4384638.
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PubMed Mentions:
34 Fields:
Translation:
Animals
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Epigenomics: Roadmap for regulation. Nature. 2015 Feb 19; 518(7539):314-6.
Romanoski CE, Glass CK, Stunnenberg HG, Wilson L, Almouzni G. PMID: 25693562.
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PubMed Mentions:
91 Fields:
Translation:
HumansCells
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The selection and function of cell type-specific enhancers. Nat Rev Mol Cell Biol. 2015 Mar; 16(3):144-54.
Heinz S, Romanoski CE, Benner C, Glass CK. PMID: 25650801; PMCID: PMC4517609.
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PubMed Mentions:
621 Fields:
Translation:
HumansAnimalsCells
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Human promoters are intrinsically directional. Mol Cell. 2015 Feb 19; 57(4):674-684.
Duttke SHC, Lacadie SA, Ibrahim MM, Glass CK, Corcoran DL, Benner C, Heinz S, Kadonaga JT, Ohler U. PMID: 25639469; PMCID: PMC4336624.
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PubMed Mentions:
93 Fields:
Translation:
HumansCells
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Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. J Lipid Res. 2015 Mar; 56(3):722-736.
Gorden DL, Myers DS, Ivanova PT, Fahy E, Maurya MR, Gupta S, Min J, Spann NJ, McDonald JG, Kelly SL, Duan J, Sullards MC, Leiker TJ, Barkley RM, Quehenberger O, Armando AM, Milne SB, Mathews TP, Armstrong MD, Li C, Melvin WV, Clements RH, Washington MK, Mendonsa AM, Witztum JL, Guan Z, Glass CK, Murphy RC, Dennis EA, Merrill AH, Russell DW, Subramaniam S, Brown HA. PMID: 25598080; PMCID: PMC4340319.
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PubMed Mentions:
198 Fields:
Translation:
HumansCTClinical Trials
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Considering the kinetics of mRNA synthesis in the analysis of the genome and epigenome reveals determinants of co-transcriptional splicing. Nucleic Acids Res. 2015 Jan; 43(2):699-707.
Davis-Turak JC, Allison K, Shokhirev MN, Ponomarenko P, Tsimring LS, Glass CK, Johnson TL, Hoffmann A. PMID: 25541195; PMCID: PMC4333389.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Environment drives selection and function of enhancers controlling tissue-specific macrophage identities. Cell. 2014 Dec 04; 159(6):1327-40.
Gosselin D, Link VM, Romanoski CE, Fonseca GJ, Eichenfield DZ, Spann NJ, Stender JD, Chun HB, Garner H, Geissmann F, Glass CK. PMID: 25480297; PMCID: PMC4364385.
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PubMed Mentions:
745 Fields:
Translation:
AnimalsCells
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Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling. Cell Metab. 2014 Nov 04; 20(5):813-826.
Gordts PLSM, Foley EM, Lawrence R, Sinha R, Lameda-Diaz C, Deng L, Nock R, Glass CK, Erbilgin A, Lusis AJ, Witztum JL, Esko JD. PMID: 25440058; PMCID: PMC4254584.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Epigenomics of macrophages. Immunol Rev. 2014 Nov; 262(1):96-112.
Gosselin D, Glass CK. PMID: 25319330; PMCID: PMC4203424.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization. Nucleic Acids Res. 2014 Nov 10; 42(20):12570-84.
Kaikkonen MU, Niskanen H, Romanoski CE, Kansanen E, Kivelä AM, Laitalainen J, Heinz S, Benner C, Glass CK, Ylä-Herttuala S. PMID: 25352550; PMCID: PMC4227755.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
-
Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output. Proc Natl Acad Sci U S A. 2014 Sep 23; 111(38):E3957-65.
Reyes G, Niederst M, Cohen-Katsenelson K, Stender JD, Kunkel MT, Chen M, Brognard J, Sierecki E, Gao T, Nowak DG, Trotman LC, Glass CK, Newton AC. PMID: 25201979; PMCID: PMC4183331.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions. EMBO Mol Med. 2014 Sep; 6(9):1124-32.
Hoeksema MA, Gijbels MJ, Van den Bossche J, van der Velden S, Sijm A, Neele AE, Seijkens T, Stöger JL, Meiler S, Boshuizen MC, Dallinga-Thie GM, Levels JH, Boon L, Mullican SE, Spann NJ, Cleutjens JP, Glass CK, Lazar MA, de Vries CJ, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. PMID: 25007801; PMCID: PMC4197860.
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PubMed Mentions:
97 Fields:
Translation:
HumansAnimalsCells
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Phospholipase A2 regulates eicosanoid class switching during inflammasome activation. Proc Natl Acad Sci U S A. 2014 Sep 02; 111(35):12746-51.
Norris PC, Gosselin D, Reichart D, Glass CK, Dennis EA. PMID: 25139986; PMCID: PMC4156727.
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PubMed Mentions:
90 Fields:
Translation:
AnimalsCells
-
Origin of myofibroblasts in the fibrotic liver in mice. Proc Natl Acad Sci U S A. 2014 Aug 12; 111(32):E3297-305.
Iwaisako K, Jiang C, Zhang M, Cong M, Moore-Morris TJ, Park TJ, Liu X, Xu J, Wang P, Paik YH, Meng F, Asagiri M, Murray LA, Hofmann AF, Iida T, Glass CK, Brenner DA, Kisseleva T. PMID: 25074909; PMCID: PMC4136601.
View in:
PubMed Mentions:
281 Fields:
Translation:
AnimalsCells
-
Enhancer RNAs and regulated transcriptional programs. Trends Biochem Sci. 2014 Apr; 39(4):170-82.
Lam MT, Li W, Rosenfeld MG, Glass CK. PMID: 24674738; PMCID: PMC4266492.
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PubMed Mentions:
285 Fields:
Translation:
HumansAnimalsCells
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Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors. Nat Neurosci. 2014 Apr; 17(4):513-21.
Crotti A, Benner C, Kerman BE, Gosselin D, Lagier-Tourenne C, Zuccato C, Cattaneo E, Gage FH, Cleveland DW, Glass CK. PMID: 24584051; PMCID: PMC4113004.
View in:
PubMed Mentions:
179 Fields:
Translation:
HumansAnimalsCells
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Modeling of eicosanoid fluxes reveals functional coupling between cyclooxygenases and terminal synthases. Biophys J. 2014 Feb 18; 106(4):966-75.
Kihara Y, Gupta S, Maurya MR, Armando A, Shah I, Quehenberger O, Glass CK, Dennis EA, Subramaniam S. PMID: 24559999; PMCID: PMC3945033.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Vespucci: a system for building annotated databases of nascent transcripts. Nucleic Acids Res. 2014 Feb; 42(4):2433-47.
Allison KA, Kaikkonen MU, Gaasterland T, Glass CK. PMID: 24304890; PMCID: PMC3936758.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Towards an understanding of cell-specific functions of signal-dependent transcription factors. J Mol Endocrinol. 2013 Dec; 51(3):T37-50.
Zhang DX, Glass CK. PMID: 24130129; PMCID: PMC4128342.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. J Biol Chem. 2013 Dec 13; 288(50):35812-23.
Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Fahy E, Subramaniam S, Cavener DR, Spector DH, Russell DW, Glass CK. PMID: 24189069; PMCID: PMC3861632.
View in:
PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Effect of natural genetic variation on enhancer selection and function. Nature. 2013 Nov 28; 503(7477):487-92.
Heinz S, Romanoski CE, Benner C, Allison KA, Kaikkonen MU, Orozco LD, Glass CK. PMID: 24121437; PMCID: PMC3994126.
View in:
PubMed Mentions:
207 Fields:
Translation:
AnimalsCells
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NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids. Cell. 2013 Sep 26; 155(1):200-214.
Li P, Spann NJ, Kaikkonen MU, Lu M, Oh DY, Fox JN, Bandyopadhyay G, Talukdar S, Xu J, Lagakos WS, Patsouris D, Armando A, Quehenberger O, Dennis EA, Watkins SM, Auwerx J, Glass CK, Olefsky JM. PMID: 24074869; PMCID: PMC4131699.
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PubMed Mentions:
107 Fields:
Translation:
AnimalsCells
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Sterols and oxysterols in immune cell function. Nat Immunol. 2013 Sep; 14(9):893-900.
Spann NJ, Glass CK. PMID: 23959186.
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PubMed Mentions:
161 Fields:
Translation:
HumansAnimals
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A combined omics study on activated macrophages--enhanced role of STATs in apoptosis, immunity and lipid metabolism. Bioinformatics. 2013 Nov 01; 29(21):2735-43.
Dinasarapu AR, Gupta S, Ram Maurya M, Fahy E, Min J, Sud M, Gersten MJ, Glass CK, Subramaniam S. PMID: 23981351; PMCID: PMC3799469.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid. EMBO Mol Med. 2013 Sep; 5(9):1443-57.
McCarthy C, Lieggi NT, Barry D, Mooney D, de Gaetano M, James WG, McClelland S, Barry MC, Escoubet-Lozach L, Li AC, Glass CK, Fitzgerald DJ, Belton O. PMID: 23964012; PMCID: PMC3799497.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription. Mol Cell. 2013 Aug 08; 51(3):310-25.
Kaikkonen MU, Spann NJ, Heinz S, Romanoski CE, Allison KA, Stender JD, Chun HB, Tough DF, Prinjha RK, Benner C, Glass CK. PMID: 23932714; PMCID: PMC3779836.
View in:
PubMed Mentions:
407 Fields:
Translation:
AnimalsCells
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Epigenomic control of the innate immune response. Curr Opin Pharmacol. 2013 Aug; 13(4):582-7.
Stender JD, Glass CK. PMID: 23816801; PMCID: PMC5733719.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages. J Lipid Res. 2013 Sep; 54(9):2525-42.
Maurya MR, Gupta S, Li X, Fahy E, Dinasarapu AR, Sud M, Brown HA, Glass CK, Murphy RC, Russell DW, Dennis EA, Subramaniam S. PMID: 23776196; PMCID: PMC3735949.
View in:
PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature. 2013 Jun 27; 498(7455):511-5.
Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, Glass CK. PMID: 23728303; PMCID: PMC3839578.
View in:
PubMed Mentions:
353 Fields:
Translation:
AnimalsCells
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Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature. 2013 Jun 27; 498(7455):516-20.
Li W, Notani D, Ma Q, Tanasa B, Nunez E, Chen AY, Merkurjev D, Zhang J, Ohgi K, Song X, Oh S, Kim HS, Glass CK, Rosenfeld MG. PMID: 23728302; PMCID: PMC3718886.
View in:
PubMed Mentions:
618 Fields:
Translation:
HumansCells
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Serum response factor indirectly regulates type I interferon-signaling in macrophages. J Interferon Cytokine Res. 2013 Oct; 33(10):588-96.
Xie L, Sullivan AL, Collier JG, Glass CK. PMID: 23705899; PMCID: PMC3793656.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Signaling by nuclear receptors. Cold Spring Harb Perspect Biol. 2013 Mar 01; 5(3):a016709.
Sever R, Glass CK. PMID: 23457262; PMCID: PMC3578364.
View in:
PubMed Mentions:
173 Fields:
Translation:
HumansCells
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Anti-inflammatory therapy in chronic disease: challenges and opportunities. Science. 2013 Jan 11; 339(6116):166-72.
Tabas I, Glass CK. PMID: 23307734; PMCID: PMC3608517.
View in:
PubMed Mentions:
502 Fields:
Translation:
HumansAnimals
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The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. Immunity. 2013 Jan 24; 38(1):106-18.
Blanc M, Hsieh WY, Robertson KA, Kropp KA, Forster T, Shui G, Lacaze P, Watterson S, Griffiths SJ, Spann NJ, Meljon A, Talbot S, Krishnan K, Covey DF, Wenk MR, Craigon M, Ruzsics Z, Haas J, Angulo A, Griffiths WJ, Glass CK, Wang Y, Ghazal P. PMID: 23273843; PMCID: PMC3556782.
View in:
PubMed Mentions:
225 Fields:
Translation:
AnimalsCells
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Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):21028-33.
Mansson R, Welinder E, Åhsberg J, Lin YC, Benner C, Glass CK, Lucas JS, Sigvardsson M, Murre C. PMID: 23213261; PMCID: PMC3529039.
View in:
PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate. Nat Immunol. 2012 Dec; 13(12):1196-204.
Lin YC, Benner C, Mansson R, Heinz S, Miyazaki K, Miyazaki M, Chandra V, Bossen C, Glass CK, Murre C. PMID: 23064439; PMCID: PMC3501570.
View in:
PubMed Mentions:
179 Fields:
Translation:
AnimalsCells
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DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation. Nat Struct Mol Biol. 2012 Nov; 19(11):1168-75.
Hu Q, Tanasa B, Trabucchi M, Li W, Zhang J, Ohgi KA, Rose DW, Glass CK, Rosenfeld MG. PMID: 23064648; PMCID: PMC3743530.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
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The transcriptional specificity of NF-κB dimers is coded within the κB DNA response elements. Cell Rep. 2012 Oct 25; 2(4):824-39.
Wang VY, Huang W, Asagiri M, Spann N, Hoffmann A, Glass C, Ghosh G. PMID: 23063365; PMCID: PMC4167904.
View in:
PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
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Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 2012 Sep 28; 151(1):138-52.
Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK. PMID: 23021221; PMCID: PMC3464914.
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PubMed Mentions:
336 Fields:
Translation:
AnimalsCells
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Regulation of microglia activation and deactivation by nuclear receptors. Glia. 2013 Jan; 61(1):104-11.
Saijo K, Crotti A, Glass CK. PMID: 22987512.
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PubMed Mentions:
86 Fields:
Translation:
HumansAnimalsCells
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Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Mol Cell. 2012 Oct 12; 48(1):28-38.
Stender JD, Pascual G, Liu W, Kaikkonen MU, Do K, Spann NJ, Boutros M, Perrimon N, Rosenfeld MG, Glass CK. PMID: 22921934; PMCID: PMC3472359.
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PubMed Mentions:
139 Fields:
Translation:
HumansAnimalsCells
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Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci U S A. 2012 Jun 12; 109(24):9448-53.
Kisseleva T, Cong M, Paik Y, Scholten D, Jiang C, Benner C, Iwaisako K, Moore-Morris T, Scott B, Tsukamoto H, Evans SM, Dillmann W, Glass CK, Brenner DA. PMID: 22566629; PMCID: PMC3386114.
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PubMed Mentions:
409 Fields:
Translation:
AnimalsCells
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Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab. 2012 May 02; 15(5):635-45.
Glass CK, Olefsky JM. PMID: 22560216; PMCID: PMC4156155.
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PubMed Mentions:
447 Fields:
Translation:
HumansAnimalsCells
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Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β. Nature. 2012 Mar 29; 485(7396):123-7.
Cho H, Zhao X, Hatori M, Yu RT, Barish GD, Lam MT, Chong LW, DiTacchio L, Atkins AR, Glass CK, Liddle C, Auwerx J, Downes M, Panda S, Evans RM. PMID: 22460952; PMCID: PMC3367514.
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PubMed Mentions:
596 Fields:
Translation:
AnimalsCells
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The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors. Circ Res. 2012 Apr 13; 110(8):e50-63.
Papac-Milicevic N, Breuss JM, Zaujec J, Ryban L, Plyushch T, Wagner GA, Fenzl S, Dremsek P, Cabaravdic M, Steiner M, Glass CK, Binder CJ, Uhrin P, Binder BR. PMID: 22427340.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2. Mol Cell. 2012 Apr 13; 46(1):91-104.
Cardamone MD, Krones A, Tanasa B, Taylor H, Ricci L, Ohgi KA, Glass CK, Rosenfeld MG, Perissi V. PMID: 22424771; PMCID: PMC3327812.
View in:
PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Roles of lineage-determining transcription factors in establishing open chromatin: lessons from high-throughput studies. Curr Top Microbiol Immunol. 2012; 356:1-15.
Heinz S, Glass CK. PMID: 21744305.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Peroxisome proliferator-activated receptor-γ agonists repress epithelial sodium channel expression in the kidney. Am J Physiol Renal Physiol. 2012 Mar 01; 302(5):F540-51.
Borsting E, Cheng VP, Glass CK, Vallon V, Cunard R. PMID: 22169011; PMCID: PMC3353644.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Mechanisms establishing TLR4-responsive activation states of inflammatory response genes. PLoS Genet. 2011 Dec; 7(12):e1002401.
Escoubet-Lozach L, Benner C, Kaikkonen MU, Lozach J, Heinz S, Spann NJ, Crotti A, Stender J, Ghisletti S, Reichart D, Cheng CS, Luna R, Ludka C, Sasik R, Garcia-Bassets I, Hoffmann A, Subramaniam S, Hardiman G, Rosenfeld MG, Glass CK. PMID: 22174696; PMCID: PMC3234212.
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PubMed Mentions:
93 Fields:
Translation:
HumansAnimalsCells
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Microglial cell origin and phenotypes in health and disease. Nat Rev Immunol. 2011 Oct 25; 11(11):775-87.
Saijo K, Glass CK. PMID: 22025055.
View in:
PubMed Mentions:
529 Fields:
Translation:
HumansCells
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PPARs and lipid ligands in inflammation and metabolism. Chem Rev. 2011 Oct 12; 111(10):6321-40.
Harmon GS, Lam MT, Glass CK. PMID: 21988241; PMCID: PMC3437919.
View in:
PubMed Mentions:
88 Fields:
Translation:
AnimalsCells
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A global clustering algorithm to identify long intergenic non-coding RNA--with applications in mouse macrophages. PLoS One. 2011; 6(9):e24051.
Garmire LX, Garmire DG, Huang W, Yao J, Glass CK, Subramaniam S. PMID: 21980340; PMCID: PMC3184070.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors. Immunity. 2011 Sep 23; 35(3):413-25.
Mercer EM, Lin YC, Benner C, Jhunjhunwala S, Dutkowski J, Flores M, Sigvardsson M, Ideker T, Glass CK, Murre C. PMID: 21903424; PMCID: PMC3183365.
View in:
PubMed Mentions:
91 Fields:
Translation:
AnimalsCells
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Specificity of eicosanoid production depends on the TLR-4-stimulated macrophage phenotype. J Leukoc Biol. 2011 Sep; 90(3):563-74.
Norris PC, Reichart D, Dumlao DS, Glass CK, Dennis EA. PMID: 21653236; PMCID: PMC3157897.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Review focus on epigenetics and the histone code in vascular biology. Cardiovasc Res. 2011 Jun 01; 90(3):402-3.
Ylä-Herttuala S, Glass CK. PMID: 21586445; PMCID: PMC3096309.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Migration of fibrocytes in fibrogenic liver injury. Am J Pathol. 2011 Jul; 179(1):189-98.
Scholten D, Reichart D, Paik YH, Lindert J, Bhattacharya J, Glass CK, Brenner DA, Kisseleva T. PMID: 21703401; PMCID: PMC3123781.
View in:
PubMed Mentions:
62 Fields:
Translation:
AnimalsCells
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Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA. Nature. 2011 May 15; 474(7351):390-4.
Wang D, Garcia-Bassets I, Benner C, Li W, Su X, Zhou Y, Qiu J, Liu W, Kaikkonen MU, Ohgi KA, Glass CK, Rosenfeld MG, Fu XD. PMID: 21572438; PMCID: PMC3117022.
View in:
PubMed Mentions:
538 Fields:
Translation:
HumansCells
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An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation. Cell. 2011 May 13; 145(4):584-95.
Saijo K, Collier JG, Li AC, Katzenellenbogen JA, Glass CK. PMID: 21565615; PMCID: PMC3433492.
View in:
PubMed Mentions:
169 Fields:
Translation:
HumansAnimalsCells
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Non-coding RNAs as regulators of gene expression and epigenetics. Cardiovasc Res. 2011 Jun 01; 90(3):430-40.
Kaikkonen MU, Lam MT, Glass CK. PMID: 21558279; PMCID: PMC3096308.
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PubMed Mentions:
335 Fields:
Translation:
HumansAnimalsCells
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Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection. J Mol Med (Berl). 2011 Oct; 89(10):997-1013.
Kisseleva T, von Köckritz-Blickwede M, Reichart D, McGillvray SM, Wingender G, Kronenberg M, Glass CK, Nizet V, Brenner DA. PMID: 21499735; PMCID: PMC3171633.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature. 2011 Feb 17; 470(7334):414-8.
Huang W, Ghisletti S, Saijo K, Gandhi M, Aouadi M, Tesz GJ, Zhang DX, Yao J, Czech MP, Goode BL, Rosenfeld MG, Glass CK. PMID: 21331046; PMCID: PMC3464905.
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PubMed Mentions:
97 Fields:
Translation:
HumansAnimalsCells
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Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism. BMC Syst Biol. 2011 Feb 08; 5:26.
Gupta S, Maurya MR, Merrill AH, Glass CK, Subramaniam S. PMID: 21303545; PMCID: PMC3047436.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Research resource: Comparative nuclear receptor atlas: basal and activated peritoneal B-1 and B-2 cells. Mol Endocrinol. 2011 Mar; 25(3):529-45.
Diehl CJ, Barish GD, Downes M, Chou MY, Heinz S, Glass CK, Evans RM, Witztum JL. PMID: 21273443; PMCID: PMC3045740.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs. Cold Spring Harb Perspect Biol. 2011 Jan 01; 3(1):a003756.
Wang X, Song X, Glass CK, Rosenfeld MG. PMID: 20573714; PMCID: PMC3003465.
View in:
PubMed Mentions:
90 Fields:
Translation:
Cells
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Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages. Mol Cell Biol. 2011 Feb; 31(4):861-75.
Sullivan AL, Benner C, Heinz S, Huang W, Xie L, Miano JM, Glass CK. PMID: 21135125; PMCID: PMC3028656.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Statins enhance formation of phagocyte extracellular traps. Cell Host Microbe. 2010 Nov 18; 8(5):445-54.
Chow OA, von Köckritz-Blickwede M, Bright AT, Hensler ME, Zinkernagel AS, Cogen AL, Gallo RL, Monestier M, Wang Y, Glass CK, Nizet V. PMID: 21075355; PMCID: PMC3008410.
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PubMed Mentions:
229 Fields:
Translation:
HumansAnimalsCells
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FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages. EMBO J. 2010 Dec 15; 29(24):4223-36.
Fan W, Morinaga H, Kim JJ, Bae E, Spann NJ, Heinz S, Glass CK, Olefsky JM. PMID: 21045807; PMCID: PMC3018786.
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PubMed Mentions:
131 Fields:
Translation:
AnimalsCells
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A mouse macrophage lipidome. J Biol Chem. 2010 Dec 17; 285(51):39976-85.
Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH, Sullards MC, Wang E, Murphy RC, Raetz CR, Garrett TA, Guan Z, Ryan AC, Russell DW, McDonald JG, Thompson BM, Shaw WA, Sud M, Zhao Y, Gupta S, Maurya MR, Fahy E, Subramaniam S. PMID: 20923771; PMCID: PMC3000979.
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PubMed Mentions:
161 Fields:
Translation:
AnimalsCells
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Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. J Biol Chem. 2010 Dec 03; 285(49):38568-79.
Sims K, Haynes CA, Kelly S, Allegood JC, Wang E, Momin A, Leipelt M, Reichart D, Glass CK, Sullards MC, Merrill AH. PMID: 20876532; PMCID: PMC2992289.
View in:
PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
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Macrophages, oxysterols and atherosclerosis. Circ J. 2010 Oct; 74(10):2045-51.
Shibata N, Glass CK. PMID: 20838002.
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PubMed Mentions:
41 Fields:
Translation:
HumansCells
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A new role for cyclic phosphatidic acid as a PPARgamma antagonist. Cell Metab. 2010 Sep 08; 12(3):207-8.
Oishi-Tanaka Y, Glass CK. PMID: 20816085.
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PubMed Mentions:
6 Fields:
-
The type I interferon signaling pathway is a target for glucocorticoid inhibition. Mol Cell Biol. 2010 Oct; 30(19):4564-74.
Flammer JR, Dobrovolna J, Kennedy MA, Chinenov Y, Glass CK, Ivashkiv LB, Rogatsky I. PMID: 20679482; PMCID: PMC2950533.
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PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
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Nuclear receptors and inflammation control: molecular mechanisms and pathophysiological relevance. Arterioscler Thromb Vasc Biol. 2010 Aug; 30(8):1542-9.
Huang W, Glass CK. PMID: 20631355; PMCID: PMC2911147.
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PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature. 2010 Jul 22; 466(7305):508-12.
Liu W, Tanasa B, Tyurina OV, Zhou TY, Gassmann R, Liu WT, Ohgi KA, Benner C, Garcia-Bassets I, Aggarwal AK, Desai A, Dorrestein PC, Glass CK, Rosenfeld MG. PMID: 20622854; PMCID: PMC3059551.
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PubMed Mentions:
243 Fields:
Translation:
HumansCells
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Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation. Mol Cell Biol. 2010 Aug; 30(16):3943-55.
Stender JD, Kim K, Charn TH, Komm B, Chang KC, Kraus WL, Benner C, Glass CK, Katzenellenbogen BS. PMID: 20547749; PMCID: PMC2916448.
View in:
PubMed Mentions:
128 Fields:
Translation:
HumansCells
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A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nat Immunol. 2010 Jul; 11(7):635-43.
Lin YC, Jhunjhunwala S, Benner C, Heinz S, Welinder E, Mansson R, Sigvardsson M, Hagman J, Espinoza CA, Dutkowski J, Ideker T, Glass CK, Murre C. PMID: 20543837; PMCID: PMC2896911.
View in:
PubMed Mentions:
314 Fields:
Translation:
AnimalsCells
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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell. 2010 May 28; 38(4):576-89.
Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK. PMID: 20513432; PMCID: PMC2898526.
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PubMed Mentions:
7931 Fields:
Translation:
AnimalsCells
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Conserved role for autophagy in Rho1-mediated cortical remodeling and blood cell recruitment. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10502-7.
Kadandale P, Stender JD, Glass CK, Kiger AA. PMID: 20498061; PMCID: PMC2890812.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Retinoid X receptor alpha controls innate inflammatory responses through the up-regulation of chemokine expression. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10626-31.
Núñez V, Alameda D, Rico D, Mota R, Gonzalo P, Cedenilla M, Fischer T, Boscá L, Glass CK, Arroyo AG, Ricote M. PMID: 20498053; PMCID: PMC2890831.
View in:
PubMed Mentions:
89 Fields:
Translation:
AnimalsCells
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Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1: possible mechanism for acceleration of atherosclerosis by subclinical endotoxemia. Circ Res. 2010 Jul 09; 107(1):56-65.
Wiesner P, Choi SH, Almazan F, Benner C, Huang W, Diehl CJ, Gonen A, Butler S, Witztum JL, Glass CK, Miller YI. PMID: 20489162; PMCID: PMC2904601.
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PubMed Mentions:
99 Fields:
Translation:
AnimalsCells
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Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells. Nat Rev Immunol. 2010 May; 10(5):365-76.
Glass CK, Saijo K. PMID: 20414208.
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PubMed Mentions:
324 Fields:
Translation:
HumansAnimalsCells
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Mechanisms underlying inflammation in neurodegeneration. Cell. 2010 Mar 19; 140(6):918-34.
Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH. PMID: 20303880; PMCID: PMC2873093.
View in:
PubMed Mentions:
1730 Fields:
Translation:
HumansAnimals
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Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice. Nat Med. 2010 Mar; 16(3):313-8.
Harmon GS, Dumlao DS, Ng DT, Barrett KE, Dennis EA, Dong H, Glass CK. PMID: 20154695; PMCID: PMC2834836.
View in:
PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
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Deconstructing repression: evolving models of co-repressor action. Nat Rev Genet. 2010 Feb; 11(2):109-23.
Perissi V, Jepsen K, Glass CK, Rosenfeld MG. PMID: 20084085.
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PubMed Mentions:
288 Fields:
Translation:
HumansAnimalsCells
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Macrophages, inflammation, and insulin resistance. Annu Rev Physiol. 2010; 72:219-46.
Olefsky JM, Glass CK. PMID: 20148674.
View in:
PubMed Mentions:
1423 Fields:
Translation:
HumansAnimalsCells
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Nuclear receptors, inflammation, and neurodegenerative diseases. Adv Immunol. 2010; 106:21-59.
Saijo K, Crotti A, Glass CK. PMID: 20728023.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Regulatory network of microRNAs in RAW 264.7 macrophage cells. Annu Int Conf IEEE Eng Med Biol Soc. 2010; 2010:6198-201.
Garmire LX, Shen Z, Briggs S, Yeo G, Subramaniam S, Glass C. PMID: 21097158.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell. 2009 Dec 11; 139(6):1069-83.
Lin C, Yang L, Tanasa B, Hutt K, Ju BG, Ohgi K, Zhang J, Rose DW, Fu XD, Glass CK, Rosenfeld MG. PMID: 19962179; PMCID: PMC2812435.
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PubMed Mentions:
323 Fields:
Translation:
HumansCells
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The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J Exp Med. 2009 Sep 28; 206(10):2079-89.
Klotz L, Burgdorf S, Dani I, Saijo K, Flossdorf J, Hucke S, Alferink J, Nowak N, Novak N, Beyer M, Mayer G, Langhans B, Klockgether T, Waisman A, Eberl G, Schultze J, Famulok M, Kolanus W, Glass C, Kurts C, Knolle PA. PMID: 19737866; PMCID: PMC2757877.
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PubMed Mentions:
182 Fields:
Translation:
HumansAnimalsCells
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Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy. Circ Res. 2009 Sep 11; 105(6):604-9.
Turunen MP, Lehtola T, Heinonen SE, Assefa GS, Korpisalo P, Girnary R, Glass CK, Väisänen S, Ylä-Herttuala S. PMID: 19696410.
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PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint. Mol Cell. 2009 Jul 10; 35(1):48-57.
Huang W, Ghisletti S, Perissi V, Rosenfeld MG, Glass CK. PMID: 19595715; PMCID: PMC2759189.
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PubMed Mentions:
69 Fields:
Translation:
AnimalsCells
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Transcriptional regulation through noncoding RNAs and epigenetic modifications. RNA Biol. 2009 Jul-Aug; 6(3):233-6.
Kurokawa R, Rosenfeld MG, Glass CK. PMID: 19411842.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol. 2009 Jun; 23(6):740-6.
McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, Evans RM, O'Malley BW. PMID: 19423650; PMCID: PMC2691684.
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PubMed Mentions:
73 Fields:
Translation:
Cells
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A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell. 2009 Apr 03; 137(1):47-59.
Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG, Gage FH, Glass CK. PMID: 19345186; PMCID: PMC2754279.
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PubMed Mentions:
504 Fields:
Translation:
AnimalsCells
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Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 2009 Mar 15; 23(6):681-93.
Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, Glass CK. PMID: 19299558; PMCID: PMC2661610.
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PubMed Mentions:
149 Fields:
Translation:
AnimalsCells
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Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature. 2009 Apr 02; 458(7238):591-6.
Cook PJ, Ju BG, Telese F, Wang X, Glass CK, Rosenfeld MG. PMID: 19234442; PMCID: PMC2692521.
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PubMed Mentions:
299 Fields:
Translation:
HumansAnimalsCells
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Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proc Natl Acad Sci U S A. 2008 12 09; 105(49):19199-204.
Hu Q, Kwon YS, Nunez E, Cardamone MD, Hutt KR, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. PMID: 19052240; PMCID: PMC2593616.
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PubMed Mentions:
143 Fields:
Translation:
HumansCells
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Regulation of macrophage function in inflammation and atherosclerosis. J Lipid Res. 2009 Apr; 50 Suppl:S277-81.
Shibata N, Glass CK. PMID: 18987388; PMCID: PMC2674700.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity. J Med Chem. 2008 Sep 25; 51(18):5758-65.
Chao EY, Caravella JA, Watson MA, Campobasso N, Ghisletti S, Billin AN, Galardi C, Wang P, Laffitte BA, Iannone MA, Goodwin BJ, Nichols JA, Parks DJ, Stewart E, Wiethe RW, Williams SP, Smallwood A, Pearce KH, Glass CK, Willson TM, Zuercher WJ, Collins JL. PMID: 18800767.
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PubMed Mentions:
16 Fields:
Translation:
Cells
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Immunology: Oxysterols hold T cells in check. Nature. 2008 Sep 04; 455(7209):40-1.
Glass CK, Saijo K. PMID: 18769427.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Evidence mandating earlier and more aggressive treatment of hypercholesterolemia. Circulation. 2008 Aug 05; 118(6):672-7.
Steinberg D, Glass CK, Witztum JL. PMID: 18678783.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimals
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Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell. 2008 Jul 11; 134(1):189.
Nunez E, Kwon YS, Hutt KR, Hu Q, Cardamone MD, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. PMID: 18630350.
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PubMed Mentions:
4 Fields:
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Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature. 2008 Jul 03; 454(7200):126-30.
Wang X, Arai S, Song X, Reichart D, Du K, Pascual G, Tempst P, Rosenfeld MG, Glass CK, Kurokawa R. PMID: 18509338; PMCID: PMC2823488.
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PubMed Mentions:
545 Fields:
Translation:
HumansCells
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Expression analysis of G Protein-Coupled Receptors in mouse macrophages. Immunome Res. 2008 Apr 29; 4:5.
Lattin JE, Schroder K, Su AI, Walker JR, Zhang J, Wiltshire T, Saijo K, Glass CK, Hume DA, Kellie S, Sweet MJ. PMID: 18442421; PMCID: PMC2394514.
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PubMed Mentions:
274
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TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints. Mol Cell. 2008 Mar 28; 29(6):755-66.
Perissi V, Scafoglio C, Zhang J, Ohgi KA, Rose DW, Glass CK, Rosenfeld MG. PMID: 18374649; PMCID: PMC2364611.
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PubMed Mentions:
92 Fields:
Translation:
HumansAnimalsCells
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Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell. 2008 Mar 21; 132(6):996-1010.
Nunez E, Kwon YS, Hutt KR, Hu Q, Cardamone MD, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. PMID: 18358812.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation. Mol Cell. 2008 Jan 18; 29(1):69-80.
Zhou W, Zhu P, Wang J, Pascual G, Ohgi KA, Lozach J, Glass CK, Rosenfeld MG. PMID: 18206970; PMCID: PMC2327256.
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PubMed Mentions:
199 Fields:
Translation:
HumansAnimalsCells
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Use of mouse models to evaluate roles of nuclear receptors and their ligands in the pathogenesis and treatment of atherosclerosis. Curr Drug Targets. 2007 Dec; 8(12):1273-87.
Li AC, Glass CK. PMID: 18220704.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms. Trends Immunol. 2007 Dec; 28(12):551-8.
Straus DS, Glass CK. PMID: 17981503.
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PubMed Mentions:
254 Fields:
Translation:
HumansAnimalsCells
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SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature. 2007 Nov 15; 450(7168):415-9.
Jepsen K, Solum D, Zhou T, McEvilly RJ, Kim HJ, Glass CK, Hermanson O, Rosenfeld MG. PMID: 17928865.
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PubMed Mentions:
221 Fields:
Translation:
HumansAnimalsCells
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A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem. 2007 Nov 30; 282(48):35279-92.
Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, Olefsky JM. PMID: 17916553.
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PubMed Mentions:
511 Fields:
Translation:
AnimalsCells
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A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. Mol Cell. 2007 Aug 17; 27(4):609-21.
Zhu P, Zhou W, Wang J, Puc J, Ohgi KA, Erdjument-Bromage H, Tempst P, Glass CK, Rosenfeld MG. PMID: 17707232; PMCID: PMC2709280.
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PubMed Mentions:
152 Fields:
Translation:
HumansAnimalsCells
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Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis. Science. 2007 Jul 13; 317(5835):248-51.
Lunyak VV, Prefontaine GG, Núñez E, Cramer T, Ju BG, Ohgi KA, Hutt K, Roy R, García-Díaz A, Zhu X, Yung Y, Montoliu L, Glass CK, Rosenfeld MG. PMID: 17626886.
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PubMed Mentions:
152 Fields:
Translation:
AnimalsCells
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 2007 Jun 14; 447(7146):799-816.
ENCODE Project Consortium, Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, Asthana S, Malhotra A, Adzhubei I, Greenbaum JA, Andrews RM, Flicek P, Boyle PJ, Cao H, Carter NP, Clelland GK, Davis S, Day N, Dhami P, Dillon SC, Dorschner MO, Fiegler H, Giresi PG, Goldy J, Hawrylycz M, Haydock A, Humbert R, James KD, Johnson BE, Johnson EM, Frum TT, Rosenzweig ER, Karnani N, Lee K, Lefebvre GC, Navas PA, Neri F, Parker SC, Sabo PJ, Sandstrom R, Shafer A, Vetrie D, Weaver M, Wilcox S, Yu M, Collins FS, Dekker J, Lieb JD, Tullius TD, Crawford GE, Sunyaev S, Noble WS, Dunham I, Denoeud F, Reymond A, Kapranov P, Rozowsky J, Zheng D, Castelo R, Frankish A, Harrow J, Ghosh S, Sandelin A, Hofacker IL, Baertsch R, Keefe D, Dike S, Cheng J, Hirsch HA, Sekinger EA, Lagarde J, Abril JF, Shahab A, Flamm C, Fried C, Hackermüller J, Hertel J, Lindemeyer M, Missal K, Tanzer A, Washietl S, Korbel J, Emanuelsson O, Pedersen JS, Holroyd N, Taylor R, Swarbreck D, Matthews N, Dickson MC, Thomas DJ, Weirauch MT, Gilbert J, Drenkow J, Bell I, Zhao X, Srinivasan KG, Sung WK, Ooi HS, Chiu KP, Foissac S, Alioto T, Brent M, Pachter L, Tress ML, Valencia A, Choo SW, Choo CY, Ucla C, Manzano C, Wyss C, Cheung E, Clark TG, Brown JB, Ganesh M, Patel S, Tammana H, Chrast J, Henrichsen CN, Kai C, Kawai J, Nagalakshmi U, Wu J, Lian Z, Lian J, Newburger P, Zhang X, Bickel P, Mattick JS, Carninci P, Hayashizaki Y, Weissman S, Hubbard T, Myers RM, Rogers J, Stadler PF, Lowe TM, Wei CL, Ruan Y, Struhl K, Gerstein M, Antonarakis SE, Fu Y, Green ED, Karaöz U, Siepel A, Taylor J, Liefer LA, Wetterstrand KA, Good PJ, Feingold EA, Guyer MS, Cooper GM, Asimenos G, Dewey CN, Hou M, Nikolaev S, Montoya-Burgos JI, Löytynoja A, Whelan S, Pardi F, Massingham T, Huang H, Zhang NR, Holmes I, Mullikin JC, Ureta-Vidal A, Paten B, Seringhaus M, Church D, Rosenbloom K, Kent WJ, Stone EA, NISC Comparative Sequencing Program, Baylor College of Medicine Human Genome Sequencing Center, Washington University Genome Sequencing Center, Broad Institute, Children's Hospital Oakland Research Institute, Batzoglou S, Goldman N, Hardison RC, Haussler D, Miller W, Sidow A, Trinklein ND, Zhang ZD, Barrera L, Stuart R, King DC, Ameur A, Enroth S, Bieda MC, Kim J, Bhinge AA, Jiang N, Liu J, Yao F, Vega VB, Lee CW, Ng P, Shahab A, Yang A, Moqtaderi Z, Zhu Z, Xu X, Squazzo S, Oberley MJ, Inman D, Singer MA, Richmond TA, Munn KJ, Rada-Iglesias A, Wallerman O, Komorowski J, Fowler JC, Couttet P, Bruce AW, Dovey OM, Ellis PD, Langford CF, Nix DA, Euskirchen G, Hartman S, Urban AE, Kraus P, Van Calcar S, Heintzman N, Kim TH, Wang K, Qu C, Hon G, Luna R, Glass CK, Rosenfeld MG, Aldred SF, Cooper SJ, Halees A, Lin JM, Shulha HP, Zhang X, Xu M, Haidar JN, Yu Y, Ruan Y, Iyer VR, Green RD, Wadelius C, Farnham PJ, Ren B, Harte RA, Hinrichs AS, Trumbower H, Clawson H, Hillman-Jackson J, Zweig AS, Smith K, Thakkapallayil A, Barber G, Kuhn RM, Karolchik D, Armengol L, Bird CP, de Bakker PI, Kern AD, Lopez-Bigas N, Martin JD, Stranger BE, Woodroffe A, Davydov E, Dimas A, Eyras E, Hallgrímsdóttir IB, Huppert J, Zody MC, Abecasis GR, Estivill X, Bouffard GG, Guan X, Hansen NF, Idol JR, Maduro VV, Maskeri B, McDowell JC, Park M, Thomas PJ, Young AC, Blakesley RW, Muzny DM, Sodergren E, Wheeler DA, Worley KC, Jiang H, Weinstock GM, Gibbs RA, Graves T, Fulton R, Mardis ER, Wilson RK, Clamp M, Cuff J, Gnerre S, Jaffe DB, Chang JL, Lindblad-Toh K, Lander ES, Koriabine M, Nefedov M, Osoegawa K, Yoshinaga Y, Zhu B, de Jong PJ. PMID: 17571346; PMCID: PMC2212820.
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PubMed Mentions:
2744 Fields:
Translation:
HumansCells
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Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J Clin Invest. 2007 Jun; 117(6):1658-69.
Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, Folian B, Subramaniam S, Gonzalez FJ, Glass CK, Ricote M. PMID: 17525798; PMCID: PMC1868788.
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PubMed Mentions:
256 Fields:
Translation:
AnimalsCells
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Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS. Cell Cycle. 2007 Jul 01; 6(13):1594-604.
Hester KD, Verhelle D, Escoubet-Lozach L, Luna R, Rose DW, Glass CK. PMID: 17525531.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature. 2007 Apr 19; 446(7138):882-7.
Wang J, Scully K, Zhu X, Cai L, Zhang J, Prefontaine GG, Krones A, Ohgi KA, Zhu P, Garcia-Bassets I, Liu F, Taylor H, Lozach J, Jayes FL, Korach KS, Glass CK, Fu XD, Rosenfeld MG. PMID: 17392792.
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PubMed Mentions:
337 Fields:
Translation:
AnimalsCells
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Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):4852-7.
Kwon YS, Garcia-Bassets I, Hutt KR, Cheng CS, Jin M, Liu D, Benner C, Wang D, Ye Z, Bibikova M, Fan JB, Duan L, Glass CK, Rosenfeld MG, Fu XD. PMID: 17360330; PMCID: PMC1821125.
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PubMed Mentions:
65 Fields:
Translation:
HumansCells
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PPARs and molecular mechanisms of transrepression. Biochim Biophys Acta. 2007 Aug; 1771(8):926-35.
Ricote M, Glass CK. PMID: 17433773; PMCID: PMC1986735.
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PubMed Mentions:
262 Fields:
Translation:
HumansAnimalsCells
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Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell. 2007 Feb 09; 128(3):505-518.
Garcia-Bassets I, Kwon YS, Telese F, Prefontaine GG, Hutt KR, Cheng CS, Ju BG, Ohgi KA, Wang J, Escoubet-Lozach L, Rose DW, Glass CK, Fu XD, Rosenfeld MG. PMID: 17289570; PMCID: PMC1994663.
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PubMed Mentions:
246 Fields:
Translation:
HumansCells
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Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma. Mol Cell. 2007 Jan 12; 25(1):57-70.
Ghisletti S, Huang W, Ogawa S, Pascual G, Lin ME, Willson TM, Rosenfeld MG, Glass CK. PMID: 17218271; PMCID: PMC1850387.
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PubMed Mentions:
282 Fields:
Translation:
HumansAnimalsCells
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Systems biology of macrophages. Adv Exp Med Biol. 2007; 598:62-79.
Maurya MR, Benner C, Pradervand S, Glass C, Subramaniam S. PMID: 17892205.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Anti-inflammatory and antidiabetic roles of PPARgamma. Novartis Found Symp. 2007; 286:183-96; discussion 196-203.
Pascual G, Sullivan AL, Ogawa S, Gamliel A, Perissi V, Rosenfeld MG, Glass CK. PMID: 18269183.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors. Pharmacol Rev. 2006 Dec; 58(4):726-41.
Michalik L, Auwerx J, Berger JP, Chatterjee VK, Glass CK, Gonzalez FJ, Grimaldi PA, Kadowaki T, Lazar MA, O'Rahilly S, Palmer CN, Plutzky J, Reddy JK, Spiegelman BM, Staels B, Wahli W. PMID: 17132851.
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PubMed Mentions:
396 Fields:
Translation:
HumansAnimalsCells
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Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter. BMC Mol Biol. 2006 Nov 29; 7:45.
Liddiard K, Welch JS, Lozach J, Heinz S, Glass CK, Greaves DR. PMID: 17134490; PMCID: PMC1698493.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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LMSD: LIPID MAPS structure database. Nucleic Acids Res. 2007 Jan; 35(Database issue):D527-32.
Sud M, Fahy E, Cotter D, Brown A, Dennis EA, Glass CK, Merrill AH, Murphy RC, Raetz CR, Russell DW, Subramaniam S. PMID: 17098933; PMCID: PMC1669719.
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PubMed Mentions:
617 Fields:
Translation:
HumansCells
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Nuclear receptors versus inflammation: mechanisms of transrepression. Trends Endocrinol Metab. 2006 Oct; 17(8):321-7.
Pascual G, Glass CK. PMID: 16942889.
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PubMed Mentions:
83 Fields:
Translation:
HumansAnimalsCells
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Normal hematopoiesis after conditional targeting of RXRalpha in murine hematopoietic stem/progenitor cells. J Leukoc Biol. 2006 Oct; 80(4):850-61.
Ricote M, Snyder CS, Leung HY, Chen J, Chien KR, Glass CK. PMID: 16888087.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science. 2006 Jun 23; 312(5781):1798-802.
Ju BG, Lunyak VV, Perissi V, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG. PMID: 16794079.
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PubMed Mentions:
473 Fields:
Translation:
HumansCells
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Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev. 2006 Jun 01; 20(11):1405-28.
Rosenfeld MG, Lunyak VV, Glass CK. PMID: 16751179.
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PubMed Mentions:
416 Fields:
Translation:
HumansAnimalsCells
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Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression. Cancer Res. 2006 Jun 01; 66(11):5565-73.
Toyo-oka K, Bowen TJ, Hirotsune S, Li Z, Jain S, Ota S, Escoubet-Lozach L, Lozach LE, Garcia-Bassets I, Bassett IG, Lozach J, Rosenfeld MG, Glass CK, Eisenman R, Ren B, Hurlin P, Wynshaw-Boris A. PMID: 16740691.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Going nuclear in metabolic and cardiovascular disease. J Clin Invest. 2006 Mar; 116(3):556-60.
Glass CK. PMID: 16511587; PMCID: PMC1386116.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimals
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Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. J Lipid Res. 2006 May; 47(5):1097-111.
Raetz CR, Garrett TA, Reynolds CM, Shaw WA, Moore JD, Smith DC, Ribeiro AA, Murphy RC, Ulevitch RJ, Fearns C, Reichart D, Glass CK, Benner C, Subramaniam S, Harkewicz R, Bowers-Gentry RC, Buczynski MW, Cooper JA, Deems RA, Dennis EA. PMID: 16479018.
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PubMed Mentions:
146 Fields:
Translation:
AnimalsCells
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Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway. Cell. 2006 Feb 10; 124(3):615-29.
Zhu P, Baek SH, Bourk EM, Ohgi KA, Garcia-Bassets I, Sanjo H, Akira S, Kotol PF, Glass CK, Rosenfeld MG, Rose DW. PMID: 16469706.
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PubMed Mentions:
137 Fields:
Translation:
HumansAnimalsCells
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Combinatorial roles of nuclear receptors in inflammation and immunity. Nat Rev Immunol. 2006 Jan; 6(1):44-55.
Glass CK, Ogawa S. PMID: 16493426.
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PubMed Mentions:
203 Fields:
Translation:
HumansAnimalsCells
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Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell. 2005 Sep 09; 122(5):707-21.
Ogawa S, Lozach J, Benner C, Pascual G, Tangirala RK, Westin S, Hoffmann A, Subramaniam S, David M, Rosenfeld MG, Glass CK. PMID: 16143103; PMCID: PMC1430687.
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PubMed Mentions:
274 Fields:
Translation:
AnimalsCells
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A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature. 2005 Sep 29; 437(7059):759-63.
Pascual G, Fong AL, Ogawa S, Gamliel A, Li AC, Perissi V, Rose DW, Willson TM, Rosenfeld MG, Glass CK. PMID: 16127449; PMCID: PMC1464798.
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PubMed Mentions:
596 Fields:
Translation:
AnimalsCells
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Gaining weight: the Keystone Symposium on PPAR and LXR. Genes Dev. 2005 Aug 01; 19(15):1737-42.
Lehrke M, Pascual G, Glass CK, Lazar MA. PMID: 16077002; PMCID: PMC1182333.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Facilitated replacement of Kupffer cells expressing a paraoxonase-1 transgene is essential for ameliorating atherosclerosis in mice. Proc Natl Acad Sci U S A. 2005 Aug 02; 102(31):11029-34.
Bradshaw G, Gutierrez A, Miyake JH, Davis KR, Li AC, Glass CK, Curtiss LK, Davis RA. PMID: 16043712; PMCID: PMC1182426.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Direct isolation and identification of promoters in the human genome. Genome Res. 2005 Jun; 15(6):830-9.
Kim TH, Barrera LO, Qu C, Van Calcar S, Trinklein ND, Cooper SJ, Luna RM, Glass CK, Rosenfeld MG, Myers RM, Ren B. PMID: 15899964; PMCID: PMC1142473.
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PubMed Mentions:
45 Fields:
Translation:
HumansCells
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A comprehensive classification system for lipids. J Lipid Res. 2005 May; 46(5):839-61.
Fahy E, Subramaniam S, Brown HA, Glass CK, Merrill AH, Murphy RC, Raetz CR, Russell DW, Seyama Y, Shaw W, Shimizu T, Spener F, van Meer G, VanNieuwenhze MS, White SH, Witztum JL, Dennis EA. PMID: 15722563.
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PubMed Mentions:
622 Fields:
Translation:
Cells
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Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway. Cell. 2004 Dec 17; 119(6):815-29.
Ju BG, Solum D, Song EJ, Lee KJ, Rose DW, Glass CK, Rosenfeld MG. PMID: 15607978.
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PubMed Mentions:
131 Fields:
Translation:
AnimalsCells
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Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis. Proc Natl Acad Sci U S A. 2004 Dec 21; 101(51):17813-8.
Valledor AF, Hsu LC, Ogawa S, Sawka-Verhelle D, Karin M, Glass CK. PMID: 15601766; PMCID: PMC539759.
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PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
-
Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma. J Clin Invest. 2004 Dec; 114(11):1564-76.
Li AC, Binder CJ, Gutierrez A, Brown KK, Plotkin CR, Pattison JW, Valledor AF, Davis RA, Willson TM, Witztum JL, Palinski W, Glass CK. PMID: 15578089; PMCID: PMC529277.
View in:
PubMed Mentions:
213 Fields:
Translation:
HumansAnimalsCells
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Factor XIIIA (cross)links AT1 receptors to atherosclerosis. Cell. 2004 Oct 29; 119(3):313-4.
Ogawa S, Glass CK. PMID: 15507203.
View in:
PubMed Mentions:
2 Fields:
-
PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis. J Lipid Res. 2004 Dec; 45(12):2161-73.
Li AC, Glass CK. PMID: 15489539.
View in:
PubMed Mentions:
121 Fields:
Translation:
HumansAnimals
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A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation. Proc Natl Acad Sci U S A. 2004 Oct 05; 101(40):14461-6.
Ogawa S, Lozach J, Jepsen K, Sawka-Verhelle D, Perissi V, Sasik R, Rose DW, Johnson RS, Rosenfeld MG, Glass CK. PMID: 15452344; PMCID: PMC521940.
View in:
PubMed Mentions:
107 Fields:
Translation:
AnimalsCells
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Repression of IFN-gamma expression by peroxisome proliferator-activated receptor gamma. J Immunol. 2004 Jun 15; 172(12):7530-6.
Cunard R, Eto Y, Muljadi JT, Glass CK, Kelly CJ, Ricote M. PMID: 15187132.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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The jensen symposium; a tribute to a pioneer in the field of nuclear receptor biology. Mol Cell. 2004 Feb 27; 13(4):459-67.
Glass CK, McDonnell DP. PMID: 14992717.
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PubMed Mentions: Fields:
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A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors. Cell. 2004 Feb 20; 116(4):511-26.
Perissi V, Aggarwal A, Glass CK, Rose DW, Rosenfeld MG. PMID: 14980219.
View in:
PubMed Mentions:
271 Fields:
Translation:
AnimalsCells
-
PE-1/METS, an antiproliferative Ets repressor factor, is induced by CREB-1/CREM-1 during macrophage differentiation. J Biol Chem. 2004 Apr 23; 279(17):17772-84.
Sawka-Verhelle D, Escoubet-Lozach L, Fong AL, Hester KD, Herzig S, Lebrun P, Glass CK. PMID: 14754893.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature. 2003 Nov 20; 426(6964):247-54.
Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG. PMID: 14628042.
View in:
PubMed Mentions:
302 Fields:
Translation:
AnimalsCells
-
Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: effects on lipid homeostasis, inflammation, and atherosclerosis. Arterioscler Thromb Vasc Biol. 2004 Feb; 24(2):230-9.
Ricote M, Valledor AF, Glass CK. PMID: 14592855.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. Mol Cell Biol. 2003 Aug; 23(16):5780-9.
Wagner BL, Valledor AF, Shao G, Daige CL, Bischoff ED, Petrowski M, Jepsen K, Baek SH, Heyman RA, Rosenfeld MG, Schulman IG, Glass CK. PMID: 12897148; PMCID: PMC166346.
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PubMed Mentions:
96 Fields:
Translation:
AnimalsCells
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PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6712-7.
Welch JS, Ricote M, Akiyama TE, Gonzalez FJ, Glass CK. PMID: 12740443; PMCID: PMC164512.
View in:
PubMed Mentions:
167 Fields:
Translation:
Cells
-
Differential recruitment of the coactivator proteins CREB-binding protein and steroid receptor coactivator-1 to peroxisome proliferator-activated receptor gamma/9-cis-retinoic acid receptor heterodimers by ligands present in oxidized low-density lipoprotein. J Endocrinol. 2003 May; 177(2):207-14.
Wigren J, Surapureddi S, Olsson AG, Glass CK, Hammarström S, Söderström M. PMID: 12740008.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3245-50.
Baek SH, Kioussi C, Briata P, Wang D, Nguyen HD, Ohgi KA, Glass CK, Wynshaw-Boris A, Rose DW, Rosenfeld MG. PMID: 12629224; PMCID: PMC152277.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP. Cancer Cell. 2003 Mar; 3(3):259-71.
Deguchi K, Ayton PM, Carapeti M, Kutok JL, Snyder CS, Williams IR, Cross NC, Glass CK, Cleary ML, Gilliland DG. PMID: 12676584.
View in:
PubMed Mentions:
89 Fields:
Translation:
HumansAnimalsCells
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Novel prostaglandin D(2)-derived activators of peroxisome proliferator-activated receptor-gamma are formed in macrophage cell cultures. Biochim Biophys Acta. 2003 Feb 20; 1631(1):35-41.
Söderström M, Wigren J, Surapureddi S, Glass CK, Hammarström S. PMID: 12573447.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
WY14,643, a PPAR alpha ligand, has profound effects on immune responses in vivo. J Immunol. 2002 Dec 15; 169(12):6806-12.
Cunard R, DiCampli D, Archer DC, Stevenson JL, Ricote M, Glass CK, Kelly CJ. PMID: 12471112.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell. 2002 Nov 27; 111(5):673-85.
Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, Herman T, Ohgi KA, Lin C, Gleiberman A, Wang J, Brault V, Ruiz-Lozano P, Nguyen HD, Kemler R, Glass CK, Wynshaw-Boris A, Rosenfeld MG. PMID: 12464179.
View in:
PubMed Mentions:
229 Fields:
Translation:
AnimalsCells
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The macrophage foam cell as a target for therapeutic intervention. Nat Med. 2002 Nov; 8(11):1235-42.
Li AC, Glass CK. PMID: 12411950.
View in:
PubMed Mentions:
234 Fields:
Translation:
HumansAnimalsCells
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Corepressor-dependent silencing of chromosomal regions encoding neuronal genes. Science. 2002 Nov 29; 298(5599):1747-52.
Lunyak VV, Burgess R, Prefontaine GG, Nelson C, Sze SH, Chenoweth J, Schwartz P, Pevzner PA, Glass C, Mandel G, Rosenfeld MG. PMID: 12399542.
View in:
PubMed Mentions:
198 Fields:
Translation:
HumansAnimalsCells
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The role of transcription factors in allergic inflammation. J Allergy Clin Immunol. 2002 Oct; 110(4):553-64.
Escoubet-Lozach L, Glass CK, Wasserman SI. PMID: 12373260.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism. J Biol Chem. 2002 Nov 08; 277(45):42821-9.
Welch JS, Escoubet-Lozach L, Sykes DB, Liddiard K, Greaves DR, Glass CK. PMID: 12215441.
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PubMed Mentions:
103 Fields:
Translation:
AnimalsCells
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Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein. Cell. 2002 Jul 12; 110(1):55-67.
Baek SH, Ohgi KA, Rose DW, Koo EH, Glass CK, Rosenfeld MG. PMID: 12150997.
View in:
PubMed Mentions:
223 Fields:
Translation:
HumansAnimalsCells
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Roles of peroxisome proliferator-activated receptor gamma in lipid homeostasis and inflammatory responses of macrophages. Curr Opin Lipidol. 2002 Jun; 13(3):305-12.
Klappacher GW, Glass CK. PMID: 12045401.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation. Cell. 2002 Apr 19; 109(2):169-80.
Klappacher GW, Lunyak VV, Sykes DB, Sawka-Verhelle D, Sage J, Brard G, Ngo SD, Gangadharan D, Jacks T, Kamps MP, Rose DW, Rosenfeld MG, Glass CK. PMID: 12007404.
View in:
PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
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Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux. Mol Cell Biol. 2002 Apr; 22(8):2607-19.
Akiyama TE, Sakai S, Lambert G, Nicol CJ, Matsusue K, Pimprale S, Lee YH, Ricote M, Glass CK, Brewer HB, Gonzalez FJ. PMID: 11909955; PMCID: PMC133709.
View in:
PubMed Mentions:
145 Fields:
Translation:
AnimalsCells
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Maternal hypercholesterolemia during pregnancy promotes early atherogenesis in LDL receptor-deficient mice and alters aortic gene expression determined by microarray. Circulation. 2002 Mar 19; 105(11):1360-7.
Napoli C, de Nigris F, Welch JS, Calara FB, Stuart RO, Glass CK, Palinski W. PMID: 11901049.
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PubMed Mentions:
55 Fields:
Translation:
Animals
-
Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors. J Immunol. 2002 Mar 15; 168(6):2795-802.
Cunard R, Ricote M, DiCampli D, Archer DC, Kahn DA, Glass CK, Kelly CJ. PMID: 11884448.
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PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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Nuclear receptor coregulators: multiple modes of modification. Trends Endocrinol Metab. 2002 Mar; 13(2):55-60.
Hermanson O, Glass CK, Rosenfeld MG. PMID: 11854019.
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PubMed Mentions:
105 Fields:
Translation:
HumansAnimalsCells
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Novel eicosanoid activators of PPAR gamma formed by RAW 264.7 macrophage cultures. Adv Exp Med Biol. 2002; 507:343-9.
Hammarstrom S, Trinks C, Wigren J, Surapureddi S, Soderstrom M, Glass CK. PMID: 12664608.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Quality of life in patients with spinal cord injury--basic issues, assessment, and recommendations. Restor Neurol Neurosci. 2002; 20(3-4):135-49.
Wood-Dauphinée S, Exner G, Bostanci B, Exner G, Glass C, Jochheim KA, Kluger P, Koller M, Krishnan KR, Post MW, Ragnarsson KT, Rommel T, Zitnay G, SCI Consensus Group. PMID: 12454362.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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New roles for PPARs in cholesterol homeostasis. Trends Pharmacol Sci. 2001 Sep; 22(9):441-3; discussion 444.
Ricote M, Glass CK. PMID: 11543857.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Coregulator codes of transcriptional regulation by nuclear receptors. J Biol Chem. 2001 Oct 05; 276(40):36865-8.
Rosenfeld MG, Glass CK. PMID: 11459854.
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PubMed Mentions:
133 Fields:
Translation:
HumansCells
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Potential roles of the peroxisome proliferator-activated receptor-gamma in macrophage biology and atherosclerosis. J Endocrinol. 2001 Jun; 169(3):461-4.
Glass CK. PMID: 11375116.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome. Hum Mol Genet. 2001 May 01; 10(10):1071-6.
Murata T, Kurokawa R, Krones A, Tatsumi K, Ishii M, Taki T, Masuno M, Ohashi H, Yanagisawa M, Rosenfeld MG, Glass CK, Hayashi Y. PMID: 11331617.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Antiatherogenic effects of thiazolidinediones? Arterioscler Thromb Vasc Biol. 2001 Mar; 21(3):295-6.
Glass CK. PMID: 11231905.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Atherosclerosis. the road ahead. Cell. 2001 Feb 23; 104(4):503-16.
Glass CK, Witztum JL. PMID: 11239408.
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PubMed Mentions:
1004 Fields:
Translation:
HumansAnimalsCells
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Regulation of somatic growth by the p160 coactivator p/CIP. Proc Natl Acad Sci U S A. 2000 Dec 05; 97(25):13549-54.
Wang Z, Rose DW, Hermanson O, Liu F, Herman T, Wu W, Szeto D, Gleiberman A, Krones A, Pratt K, Rosenfeld R, Glass CK, Rosenfeld MG. PMID: 11087842; PMCID: PMC17613.
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PubMed Mentions:
84 Fields:
Translation:
AnimalsCells
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Mildly oxidized low density lipoprotein activates multiple apoptotic signaling pathways in human coronary cells. FASEB J. 2000 Oct; 14(13):1996-2007.
Napoli C, Quehenberger O, De Nigris F, Abete P, Glass CK, Palinski W. PMID: 11023984.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell. 2000 Sep 15; 102(6):753-63.
Jepsen K, Hermanson O, Onami TM, Gleiberman AS, Lunyak V, McEvilly RJ, Kurokawa R, Kumar V, Liu F, Seto E, Hedrick SM, Mandel G, Glass CK, Rose DW, Rosenfeld MG. PMID: 11030619.
View in:
PubMed Mentions:
212 Fields:
Translation:
AnimalsCells
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Liver biopsies in adult hemophiliacs with hepatitis C: a United States center's experience. Am J Gastroenterol. 2000 Sep; 95(9):2374-6.
Venkataramani A, Behling C, Rond R, Glass C, Lyche K. PMID: 11007246.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma. J Clin Invest. 2000 Sep; 106(6):793-802.
Han KH, Chang MK, Boullier A, Green SR, Li A, Glass CK, Quehenberger O. PMID: 10995790; PMCID: PMC381395.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Polymerase chain reaction-based method for quantifying recruitment of monocytes to mouse atherosclerotic lesions in vivo: enhancement by tumor necrosis factor-alpha and interleukin-1 beta. Arterioscler Thromb Vasc Biol. 2000 Aug; 20(8):1976-82.
Kim CJ, Khoo JC, Gillotte-Taylor K, Li A, Palinski W, Glass CK, Steinberg D. PMID: 10938020.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice. J Clin Invest. 2000 Aug; 106(4):523-31.
Li AC, Brown KK, Silvestre MJ, Willson TM, Palinski W, Glass CK. PMID: 10953027; PMCID: PMC380255.
View in:
PubMed Mentions:
233 Fields:
Translation:
HumansAnimalsCells
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Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene. Mol Cell Biol. 2000 Jul; 20(13):4699-707.
Li M, Pascual G, Glass CK. PMID: 10848596; PMCID: PMC85890.
View in:
PubMed Mentions:
123 Fields:
Translation:
AnimalsCells
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The histone deacetylase-3 complex contains nuclear receptor corepressors. Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13):7202-7.
Wen YD, Perissi V, Staszewski LM, Yang WM, Krones A, Glass CK, Rosenfeld MG, Seto E. PMID: 10860984; PMCID: PMC16523.
View in:
PubMed Mentions:
161 Fields:
Translation:
HumansCells
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15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway. Proc Natl Acad Sci U S A. 2000 Apr 25; 97(9):4844-9.
Straus DS, Pascual G, Li M, Welch JS, Ricote M, Hsiang CH, Sengchanthalangsy LL, Ghosh G, Glass CK. PMID: 10781090; PMCID: PMC18320.
View in:
PubMed Mentions:
277 Fields:
Translation:
HumansAnimalsCells
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Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):4363-8.
Llopis J, Westin S, Ricote M, Wang Z, Cho CY, Kurokawa R, Mullen TM, Rose DW, Rosenfeld MG, Tsien RY, Glass CK, Wang J. PMID: 10760302; PMCID: PMC18247.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
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The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 2000 Jan 15; 14(2):121-41.
Glass CK, Rosenfeld MG. PMID: 10652267.
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PubMed Mentions:
734 Fields:
Translation:
HumansAnimalsCells
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Nuclear receptor coactivators. Adv Pharmacol. 2000; 47:89-112.
Westin S, Rosenfeld MG, Glass CK. PMID: 10582085.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Regulation of macrophage gene expression by the peroxisome proliferator-activated receptor-gamma. Horm Res. 2000; 54(5-6):275-80.
Ricote M, Welch JS, Glass CK. PMID: 11595817.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Molecular determinants of nuclear receptor-corepressor interaction. Genes Dev. 1999 Dec 15; 13(24):3198-208.
Perissi V, Staszewski LM, McInerney EM, Kurokawa R, Krones A, Rose DW, Lambert MH, Milburn MV, Glass CK, Rosenfeld MG. PMID: 10617569; PMCID: PMC317209.
View in:
PubMed Mentions:
158 Fields:
Translation:
HumansAnimalsCells
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The peroxisome proliferator-activated receptor(PPARgamma) as a regulator of monocyte/macrophage function. J Leukoc Biol. 1999 Nov; 66(5):733-9.
Ricote M, Huang JT, Welch JS, Glass CK. PMID: 10577502.
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PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsCells
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Influence of maternal hypercholesterolaemia during pregnancy on progression of early atherosclerotic lesions in childhood: Fate of Early Lesions in Children (FELIC) study. Lancet. 1999 Oct 09; 354(9186):1234-41.
Napoli C, Glass CK, Witztum JL, Deutsch R, D'Armiento FP, Palinski W. PMID: 10520631.
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PubMed Mentions:
148 Fields:
Translation:
Humans
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PCR-based cloning and segregation analysis of functional gene homologues in Beta vulgaris. Mol Gen Genet. 1999 Oct; 262(3):515-24.
Schneider K, Borchardt DC, Schäfer-Pregl R, Nagl N, Glass C, Jeppsson A, Gebhardt C, Salamini F. PMID: 10589840.
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PubMed Mentions:
17 Fields:
Translation:
Animals
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Transcriptional activation by NF-kappaB requires multiple coactivators. Mol Cell Biol. 1999 Sep; 19(9):6367-78.
Sheppard KA, Rose DW, Haque ZK, Kurokawa R, McInerney E, Westin S, Thanos D, Rosenfeld MG, Glass CK, Collins T. PMID: 10454583; PMCID: PMC84607.
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PubMed Mentions:
142 Fields:
Translation:
AnimalsCells
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RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex. Nat Genet. 1999 Aug; 22(4):394-9.
Bach I, Rodriguez-Esteban C, Carrière C, Bhushan A, Krones A, Rose DW, Glass CK, Andersen B, Izpisúa Belmonte JC, Rosenfeld MG. PMID: 10431247.
View in:
PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase. Nature. 1999 Jul 22; 400(6742):378-82.
Huang JT, Welch JS, Ricote M, Binder CJ, Willson TM, Kelly C, Witztum JL, Funk CD, Conrad D, Glass CK. PMID: 10432118.
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PubMed Mentions:
289 Fields:
Translation:
HumansAnimalsCells
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Coactivator and corepressor complexes in nuclear receptor function. Curr Opin Genet Dev. 1999 Apr; 9(2):140-7.
Xu L, Glass CK, Rosenfeld MG. PMID: 10322133.
View in:
PubMed Mentions:
266 Fields:
Translation:
Animals
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Factor-specific modulation of CREB-binding protein acetyltransferase activity. Proc Natl Acad Sci U S A. 1999 Mar 30; 96(7):3652-7.
Perissi V, Dasen JS, Kurokawa R, Wang Z, Korzus E, Rose DW, Glass CK, Rosenfeld MG. PMID: 10097092; PMCID: PMC22349.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Paradoxical effect on atherosclerosis of hormone-sensitive lipase overexpression in macrophages. J Lipid Res. 1999 Mar; 40(3):397-404.
Escary JL, Choy HA, Reue K, Wang XP, Castellani LW, Glass CK, Lusis AJ, Schotz MC. PMID: 10064727.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Mol Cell Biol. 1998 Dec; 18(12):7176-84.
Lutterbach B, Westendorf JJ, Linggi B, Patten A, Moniwa M, Davie JR, Huynh KD, Bardwell VJ, Lavinsky RM, Rosenfeld MG, Glass C, Seto E, Hiebert SW. PMID: 9819404; PMCID: PMC109299.
View in:
PubMed Mentions:
163 Fields:
Translation:
HumansCells
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Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1. J Biol Chem. 1998 Nov 06; 273(45):29291-4.
Sheppard KA, Phelps KM, Williams AJ, Thanos D, Glass CK, Rosenfeld MG, Gerritsen ME, Collins T. PMID: 9792627.
View in:
PubMed Mentions:
73 Fields:
Translation:
AnimalsCells
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Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev. 1998 Nov 01; 12(21):3357-68.
McInerney EM, Rose DW, Flynn SE, Westin S, Mullen TM, Krones A, Inostroza J, Torchia J, Nolte RT, Assa-Munt N, Milburn MV, Glass CK, Rosenfeld MG. PMID: 9808623; PMCID: PMC317227.
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PubMed Mentions:
194 Fields:
Translation:
AnimalsCells
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Signal-specific co-activator domain requirements for Pit-1 activation. Nature. 1998 Sep 17; 395(6699):301-6.
Xu L, Lavinsky RM, Dasen JS, Flynn SE, McInerney EM, Mullen TM, Heinzel T, Szeto D, Korzus E, Kurokawa R, Aggarwal AK, Rose DW, Glass CK, Rosenfeld MG. PMID: 9751061.
View in:
PubMed Mentions:
69 Fields:
Translation:
HumansCells
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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature. 1998 Sep 10; 395(6698):137-43.
Nolte RT, Wisely GB, Westin S, Cobb JE, Lambert MH, Kurokawa R, Rosenfeld MG, Willson TM, Glass CK, Milburn MV. PMID: 9744270.
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PubMed Mentions:
546 Fields:
Translation:
HumansCells
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Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators. Nature. 1998 Sep 10; 395(6698):199-202.
Westin S, Kurokawa R, Nolte RT, Wisely GB, McInerney EM, Rose DW, Milburn MV, Rosenfeld MG, Glass CK. PMID: 9744281.
View in:
PubMed Mentions:
100 Fields:
Translation:
Cells
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Transcriptional activation of scavenger receptor expression in human smooth muscle cells requires AP-1/c-Jun and C/EBPbeta: both AP-1 binding and JNK activation are induced by phorbol esters and oxidative stress. Arterioscler Thromb Vasc Biol. 1998 Sep; 18(9):1440-9.
Mietus-Snyder M, Glass CK, Pitas RE. PMID: 9743233.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Mol Cell. 1998 Jul; 2(1):33-42.
Laherty CD, Billin AN, Lavinsky RM, Yochum GS, Bush AC, Sun JM, Mullen TM, Davie JR, Rose DW, Glass CK, Rosenfeld MG, Ayer DE, Eisenman RN. PMID: 9702189.
View in:
PubMed Mentions:
91 Fields:
Translation:
HumansAnimalsCells
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Differential utilization of Ras signaling pathways by macrophage colony-stimulating factor (CSF) and granulocyte-macrophage CSF receptors during macrophage differentiation. Mol Cell Biol. 1998 Jul; 18(7):3851-61.
Guidez F, Li AC, Horvai A, Welch JS, Glass CK. PMID: 9632769; PMCID: PMC108969.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc Natl Acad Sci U S A. 1998 Jun 23; 95(13):7614-9.
Ricote M, Huang J, Fajas L, Li A, Welch J, Najib J, Witztum JL, Auwerx J, Palinski W, Glass CK. PMID: 9636198; PMCID: PMC22700.
View in:
PubMed Mentions:
174 Fields:
Translation:
HumansAnimalsCells
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Co-activators and co-repressors in the integration of transcriptional responses. Curr Opin Cell Biol. 1998 Jun; 10(3):373-83.
Torchia J, Glass C, Rosenfeld MG. PMID: 9640539.
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PubMed Mentions:
147 Fields:
Translation:
AnimalsCells
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Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):2920-5.
Lavinsky RM, Jepsen K, Heinzel T, Torchia J, Mullen TM, Schiff R, Del-Rio AL, Ricote M, Ngo S, Gemsch J, Hilsenbeck SG, Osborne CK, Glass CK, Rosenfeld MG, Rose DW. PMID: 9501191; PMCID: PMC19670.
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PubMed Mentions:
148 Fields:
Translation:
HumansAnimalsCells
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The macrosialin promoter directs high levels of transcriptional activity in macrophages dependent on combinatorial interactions between PU.1 and c-Jun. J Biol Chem. 1998 Feb 27; 273(9):5389-99.
Li AC, Guidez FR, Collier JG, Glass CK. PMID: 9479000.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Differential use of CREB binding protein-coactivator complexes. Science. 1998 Jan 30; 279(5351):700-3.
Kurokawa R, Kalafus D, Ogliastro MH, Kioussi C, Xu L, Torchia J, Rosenfeld MG, Glass CK. PMID: 9445474.
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PubMed Mentions:
58 Fields:
Translation:
HumansAnimalsCells
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Transcription factor-specific requirements for coactivators and their acetyltransferase functions. Science. 1998 Jan 30; 279(5351):703-7.
Korzus E, Torchia J, Rose DW, Xu L, Kurokawa R, McInerney EM, Mullen TM, Glass CK, Rosenfeld MG. PMID: 9445475.
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PubMed Mentions:
178 Fields:
Translation:
HumansCells
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The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature. 1998 Jan 01; 391(6662):79-82.
Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. PMID: 9422508.
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PubMed Mentions:
1049 Fields:
Translation:
HumansCells
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Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex. Proc Natl Acad Sci U S A. 1997 Dec 23; 94(26):14400-5.
Zamir I, Dawson J, Lavinsky RM, Glass CK, Rosenfeld MG, Lazar MA. PMID: 9405624; PMCID: PMC24996.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Activated lymphocytes increase expression of 5-lipoxygenase and its activating protein in THP-1 cells. Am J Physiol. 1997 12; 273(6):C2057-64.
Ring WL, Riddick CA, Baker JR, Glass CK, Bigby TD. PMID: 9435513.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Characterization of the chromatin binding activity of lamina-associated polypeptide (LAP) 2. Biochem Biophys Res Commun. 1997 Sep 08; 238(1):240-6.
Furukawa K, Glass C, Kondo T. PMID: 9299486.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature. 1997 Jun 12; 387(6634):677-84.
Torchia J, Rose DW, Inostroza J, Kamei Y, Westin S, Glass CK, Rosenfeld MG. PMID: 9192892.
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PubMed Mentions:
372 Fields:
Translation:
HumansAnimalsCells
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Differential effects of nuclear receptor corepressor (N-CoR) expression levels on retinoic acid receptor-mediated repression support the existence of dynamically regulated corepressor complexes. Mol Endocrinol. 1997 Jun; 11(6):682-92.
Söderström M, Vo A, Heinzel T, Lavinsky RM, Yang WM, Seto E, Peterson DA, Rosenfeld MG, Glass CK. PMID: 9171232.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Regulation of scavenger receptor expression in smooth muscle cells by protein kinase C: a role for oxidative stress. Arterioscler Thromb Vasc Biol. 1997 May; 17(5):969-78.
Mietus-Snyder M, Friera A, Glass CK, Pitas RE. PMID: 9157963.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Mechanisms of transcriptional activation by retinoic acid receptors. Biochem Soc Trans. 1997 May; 25(2):602-5.
Glass CK, Rosenfeld MG, Rose DW, Kurokawa R, Kamei Y, Xu L, Torchia J, Ogliastro MH, Westin S. PMID: 9191164.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature. 1997 May 01; 387(6628):43-8.
Heinzel T, Lavinsky RM, Mullen TM, Söderstrom M, Laherty CD, Torchia J, Yang WM, Brard G, Ngo SD, Davie JR, Seto E, Eisenman RN, Rose DW, Glass CK, Rosenfeld MG. PMID: 9139820.
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PubMed Mentions:
376 Fields:
Translation:
HumansAnimalsCells
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A new approach to determining the rates of recruitment of circulating leukocytes into tissues: application to the measurement of leukocyte recruitment into atherosclerotic lesions. Proc Natl Acad Sci U S A. 1997 Apr 15; 94(8):4040-4.
Steinberg D, Khoo JC, Glass CK, Palinski W, Almazan F. PMID: 9108101; PMCID: PMC20564.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Nuclear receptor coactivators. Curr Opin Cell Biol. 1997 Apr; 9(2):222-32.
Glass CK, Rose DW, Rosenfeld MG. PMID: 9069256.
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PubMed Mentions:
116 Fields:
Translation:
HumansAnimalsCells
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Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors. Mol Cell Biol. 1997 Apr; 17(4):2166-76.
DiRenzo J, Söderstrom M, Kurokawa R, Ogliastro MH, Ricote M, Ingrey S, Hörlein A, Rosenfeld MG, Glass CK. PMID: 9121466; PMCID: PMC232065.
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PubMed Mentions:
64 Fields:
Translation:
AnimalsCells
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Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1074-9.
Horvai AE, Xu L, Korzus E, Brard G, Kalafus D, Mullen TM, Rose DW, Rosenfeld MG, Glass CK. PMID: 9037008; PMCID: PMC19746.
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PubMed Mentions:
95 Fields:
Translation:
HumansAnimalsCells
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Responding to parental concerns after a prenatal diagnosis of trisomy 21. J Dev Behav Pediatr. 1997 Feb; 18(1):42-6.
Stein MT, Scioscia A, Jones KL, Cohen WI, Glass CK, Glass RF. PMID: 9055149.
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PubMed Mentions: Fields:
Translation:
Humans
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Constitutive retinoid receptors expressed from adenovirus vectors that specifically activate chromosomal target genes required for differentiation of promyelocytic leukemia and teratocarcinoma cells. J Virol. 1996 Oct; 70(10):7182-9.
Lipkin SM, Grider TL, Heyman RA, Glass CK, Gage FH. PMID: 8794365; PMCID: PMC190771.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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A nuclear hormone receptor corepressor mediates transcriptional silencing by receptors with distinct repression domains. Mol Cell Biol. 1996 Oct; 16(10):5458-65.
Zamir I, Harding HP, Atkins GB, Hörlein A, Glass CK, Rosenfeld MG, Lazar MA. PMID: 8816459; PMCID: PMC231546.
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PubMed Mentions:
86 Fields:
Translation:
HumansCells
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Some new twists in the regulation of gene expression by thyroid hormone and retinoic acid receptors. J Endocrinol. 1996 Sep; 150(3):349-57.
Glass CK. PMID: 8882153.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell. 1996 May 03; 85(3):403-14.
Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, Lin SC, Heyman RA, Rose DW, Glass CK, Rosenfeld MG. PMID: 8616895.
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PubMed Mentions:
524 Fields:
Translation:
AnimalsCells
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The humoral hypercalcemia of benignancy. A newly appreciated syndrome. Am J Clin Pathol. 1996 Apr; 105(4):487-92.
Knecht TP, Behling CA, Burton DW, Glass CK, Deftos LJ. PMID: 8604692.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Positive regulation of cdc2 gene activity by protein phosphatase type 2A. J Biol Chem. 1996 Mar 15; 271(11):5988-92.
Jaramillo-Babb VL, Sugarmans JL, Scavetta R, Wang SJ, Berndt N, Born TL, Glass CK, Schönthal AH. PMID: 8626381.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature. 1995 Oct 05; 377(6548):397-404.
Hörlein AJ, Näär AM, Heinzel T, Torchia J, Gloss B, Kurokawa R, Ryan A, Kamei Y, Söderström M, Glass CK, et al. PMID: 7566114.
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PubMed Mentions:
578 Fields:
Translation:
HumansAnimalsCells
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Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature. 1995 Oct 05; 377(6548):451-4.
Kurokawa R, Söderström M, Hörlein A, Halachmi S, Brown M, Rosenfeld MG, Glass CK. PMID: 7566126.
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PubMed Mentions:
143 Fields:
Translation:
HumansCells
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A chromatin binding site in the tail domain of nuclear lamins that interacts with core histones. J Cell Biol. 1995 Oct; 131(1):33-44.
Taniura H, Glass C, Gerace L. PMID: 7559784; PMCID: PMC2120604.
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PubMed Mentions:
113 Fields:
Translation:
HumansAnimalsCells
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Humoral hypercalcaemia of "benignancy". Lancet. 1995 Sep 09; 346(8976):711-2.
Knecht TP, Behling CA, Burton DW, Glass CK, Deftos LJ. PMID: 7658859.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain. Genes Dev. 1995 Aug 15; 9(16):1992-2006.
Holloway JM, Szeto DP, Scully KM, Glass CK, Rosenfeld MG. PMID: 7649480.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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Scavenger receptor A gene regulatory elements target gene expression to macrophages and to foam cells of atherosclerotic lesions. Proc Natl Acad Sci U S A. 1995 Jun 06; 92(12):5391-5.
Horvai A, Palinski W, Wu H, Moulton KS, Kalla K, Glass CK. PMID: 7777517; PMCID: PMC41700.
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PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
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Identification of a cell-type-specific and E2F-independent mechanism for repression of cdc2 transcription. Mol Cell Biol. 1995 Jun; 15(6):3282-90.
Sugarman JL, Schönthal AH, Glass CK. PMID: 7760824; PMCID: PMC230561.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Neutrophils and monocytes express high levels of PU.1 (Spi-1) but not Spi-B. Blood. 1995 May 15; 85(10):2918-28.
Chen HM, Zhang P, Voso MT, Hohaus S, Gonzalez DA, Glass CK, Zhang DE, Tenen DG. PMID: 7742552.
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PubMed Mentions:
57 Fields:
Translation:
HumansAnimalsCells
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Retinoic acid receptor alpha suppresses transformation by v-myb. Mol Cell Biol. 1995 May; 15(5):2474-81.
Smarda J, Sugarman J, Glass C, Lipsick J. PMID: 7739532; PMCID: PMC230477.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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The influence of molecular biology on our understanding of lipoprotein metabolism and the pathobiology of atherosclerosis. Adv Genet. 1995; 32:141-98.
Knecht TP, Glass CK. PMID: 7741021.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding. Nature. 1994 Oct 06; 371(6497):528-31.
Kurokawa R, DiRenzo J, Boehm M, Sugarman J, Gloss B, Rosenfeld MG, Heyman RA, Glass CK. PMID: 7935766.
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PubMed Mentions:
118 Fields:
Translation:
HumansCells
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Cell-specific expression of the macrophage scavenger receptor gene is dependent on PU.1 and a composite AP-1/ets motif. Mol Cell Biol. 1994 Jul; 14(7):4408-18.
Moulton KS, Semple K, Wu H, Glass CK. PMID: 8007948; PMCID: PMC358812.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers. Endocr Rev. 1994 Jun; 15(3):391-407.
Glass CK. PMID: 8076589.
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PubMed Mentions:
148 Fields:
Translation:
HumansAnimalsCells
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Delineation of three different thyroid hormone-response elements in promoter of rat sarcoplasmic reticulum Ca2+ATPase gene. Demonstration that retinoid X receptor binds 5' to thyroid hormone receptor in response element 1. J Biol Chem. 1994 Apr 29; 269(17):13021-9.
Hartong R, Wang N, Kurokawa R, Lazar MA, Glass CK, Apriletti JW, Dillmann WH. PMID: 8175722.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Combinatorial interactions between AP-1 and ets domain proteins contribute to the developmental regulation of the macrophage scavenger receptor gene. Mol Cell Biol. 1994 Mar; 14(3):2129-39.
Wu H, Moulton K, Horvai A, Parik S, Glass CK. PMID: 8114743; PMCID: PMC358573.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers. Genes Dev. 1993 Jul; 7(7B):1423-35.
Kurokawa R, Yu VC, Näär A, Kyakumoto S, Han Z, Silverman S, Rosenfeld MG, Glass CK. PMID: 8392479.
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PubMed Mentions:
92 Fields:
Translation:
HumansCells
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Synergistic interactions between Pit-1 and other elements are required for effective somatotroph rat growth hormone gene expression in transgenic mice. Mol Endocrinol. 1993 May; 7(5):694-701.
Lira SA, Kalla KA, Glass CK, Drolet DW, Rosenfeld MG. PMID: 8316253.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Interaction between the thyroid hormone receptor and co-factors on the promoter of the gene encoding phospho enol pyruvate carboxykinase. Biochim Biophys Acta. 1993 Feb 20; 1172(1-2):82-8.
Schmidt ED, van Beeren M, Glass CK, Wiersinga WM, Lamers WH. PMID: 8382533.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Macrophage scavenger receptors and atherosclerosis. Trends Cardiovasc Med. 1992 Nov-Dec; 2(6):220-5.
Wu H, Moulton KS, Glass CK. PMID: 21239245.
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PubMed Mentions:
2 Fields:
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Regulated expression of the human acetylated low density lipoprotein receptor gene and isolation of promoter sequences. Proc Natl Acad Sci U S A. 1992 Sep 01; 89(17):8102-6.
Moulton KS, Wu H, Barnett J, Parthasarathy S, Glass CK. PMID: 1518836; PMCID: PMC49864.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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A negative retinoic acid response element in the rat oxytocin promoter restricts transcriptional stimulation by heterologous transactivation domains. Proc Natl Acad Sci U S A. 1992 Feb 15; 89(4):1209-13.
Lipkin SM, Nelson CA, Glass CK, Rosenfeld MG. PMID: 1311087; PMCID: PMC48418.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Regulation of gene expression by thyroid hormones and retinoic acid. Genet Eng (N Y). 1992; 14:185-209.
Lipkin SM, Rosenfeld MG, Glass CK. PMID: 1369379.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell. 1991 Dec 20; 67(6):1251-66.
Yu VC, Delsert C, Andersen B, Holloway JM, Devary OV, Näär AM, Kim SY, Boutin JM, Glass CK, Rosenfeld MG. PMID: 1662118.
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PubMed Mentions:
286 Fields:
Translation:
AnimalsCells
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Regulation of gene expression by retinoic acid receptors. DNA Cell Biol. 1991 Nov; 10(9):623-38.
Glass CK, DiRenzo J, Kurokawa R, Han ZH. PMID: 1661598.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors. Cell. 1991 Jun 28; 65(7):1267-79.
Näär AM, Boutin JM, Lipkin SM, Yu VC, Holloway JM, Glass CK, Rosenfeld MG. PMID: 1648451.
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PubMed Mentions:
158 Fields:
Translation:
HumansAnimalsCells
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Regulation of gene expression by the thyroid hormone receptor. Biochim Biophys Acta. 1990 Dec 11; 1032(2-3):157-76.
Glass CK, Holloway JM. PMID: 2261492.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Multiple cell type-specific proteins differentially regulate target sequence recognition by the alpha retinoic acid receptor. Cell. 1990 Nov 16; 63(4):729-38.
Glass CK, Devary OV, Rosenfeld MG. PMID: 2171781.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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The C'-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity. Proc Natl Acad Sci U S A. 1990 Oct; 87(20):8160-4.
Holloway JM, Glass CK, Adler S, Nelson CA, Rosenfeld MG. PMID: 2236029; PMCID: PMC54912.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Ligand-activated thyroid hormone and retinoic acid receptors inhibit growth factor receptor promoter expression. Cell. 1990 Sep 21; 62(6):1165-75.
Hudson LG, Santon JB, Glass CK, Gill GN. PMID: 2169350.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions. Proc Natl Acad Sci U S A. 1990 Sep; 87(18):6959-63.
Ylä-Herttuala S, Rosenfeld ME, Parthasarathy S, Glass CK, Sigal E, Witztum JL, Steinberg D. PMID: 1698286; PMCID: PMC54661.
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PubMed Mentions:
75 Fields:
Translation:
HumansAnimalsCells
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Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer. Cell. 1989 Nov 17; 59(4):697-708.
Glass CK, Lipkin SM, Devary OV, Rosenfeld MG. PMID: 2555064.
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PubMed Mentions:
111 Fields:
Translation:
HumansAnimalsCells
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Analysis of 'color PCR' by automatic DNA sequencer. Nucleic Acids Res. 1989 Sep 25; 17(18):7538.
Zimran A, Glass C, Thorpe VS, Beutler E. PMID: 2798114; PMCID: PMC334848.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Retinoic acid and thyroid hormone induce gene expression through a common responsive element. Nature. 1988 Nov 17; 336(6196):262-5.
Umesono K, Giguere V, Glass CK, Rosenfeld MG, Evans RM. PMID: 2848197.
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PubMed Mentions:
134 Fields:
Translation:
HumansCells
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Isolation, sequence, and differential expression of a human K7 gene in simple epithelial cells. J Cell Biol. 1988 Oct; 107(4):1337-50.
Glass C, Fuchs E. PMID: 2459129; PMCID: PMC2115265.
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PubMed Mentions:
14 Fields:
Translation:
Cells
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The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements. Cell. 1988 Jul 29; 54(3):313-23.
Glass CK, Holloway JM, Devary OV, Rosenfeld MG. PMID: 3396073.
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PubMed Mentions:
158 Fields:
Translation:
AnimalsCells
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Identification of rat growth hormone genomic sequences targeting pituitary expression in transgenic mice. Proc Natl Acad Sci U S A. 1988 Jul; 85(13):4755-9.
Lira SA, Crenshaw EB, Glass CK, Swanson LW, Rosenfeld MG. PMID: 3387436; PMCID: PMC280514.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Response and binding elements for ligand-dependent positive transcription factors integrate positive and negative regulation of gene expression. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 1:545-56.
Rosenfeld MG, Glass CK, Adler S, Crenshaw EB, He X, Lira SA, Elsholtz HP, Mangalam HJ, Holloway JM, Nelson C, et al. PMID: 3254780.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone. Nature. 1987 Oct 22-28; 329(6141):738-41.
Glass CK, Franco R, Weinberger C, Albert VR, Evans RM, Rosenfeld MG. PMID: 3313046.
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PubMed Mentions:
74 Fields:
Translation:
AnimalsCells
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Synthetic high density lipoprotein particles. Application to studies of the apoprotein specificity for selective uptake of cholesterol esters. J Biol Chem. 1987 Feb 25; 262(6):2435-42.
Pittman RC, Glass CK, Atkinson D, Small DM. PMID: 3029080.
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PubMed Mentions:
25 Fields:
Translation:
Animals
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Synchronized synthesis and intracellular transport of serum albumin and apolipoprotein B in cultured rat hepatocytes as studied by double immunofluorescence. J Histochem Cytochem. 1986 Sep; 34(9):1223-30.
Keller GA, Glass C, Louvard D, Steinberg D, Singer SJ. PMID: 3525668.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Sequence and expression of a human type II mesothelial keratin. J Cell Biol. 1985 Dec; 101(6):2366-73.
Glass C, Kim KH, Fuchs E. PMID: 2415537; PMCID: PMC2114014.
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PubMed Mentions:
12 Fields:
Translation:
Cells
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Uptake of high-density lipoprotein-associated apoprotein A-I and cholesterol esters by 16 tissues of the rat in vivo and by adrenal cells and hepatocytes in vitro. J Biol Chem. 1985 Jan 25; 260(2):744-50.
Glass C, Pittman RC, Civen M, Steinberg D. PMID: 3918032.
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PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
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Lipoprotein synthesis and secretion by cultured rat hepatocytes. Parallel inhibition of secretion of VLDL, HDL and albumin by monensin. Biochim Biophys Acta. 1984 Oct 04; 795(3):574-88.
Melin B, Keller G, Glass C, Weinstein DB, Steinberg D. PMID: 6477962.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Dissociation of tissue uptake of cholesterol ester from that of apoprotein A-I of rat plasma high density lipoprotein: selective delivery of cholesterol ester to liver, adrenal, and gonad. Proc Natl Acad Sci U S A. 1983 Sep; 80(17):5435-9.
Glass C, Pittman RC, Weinstein DB, Steinberg D. PMID: 6412229; PMCID: PMC384271.
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PubMed Mentions:
100 Fields:
Translation:
Animals
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A radioiodinated, intracellularly trapped ligand for determining the sites of plasma protein degradation in vivo. Biochem J. 1983 Jun 15; 212(3):791-800.
Pittman RC, Carew TE, Glass CK, Green SR, Taylor CA, Attie AD. PMID: 6882394; PMCID: PMC1153156.
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PubMed Mentions:
73 Fields:
Translation:
HumansAnimalsCells
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Tissue sites of degradation of apoprotein A-I in the rat. J Biol Chem. 1983 Jun 10; 258(11):7161-7.
Glass CK, Pittman RC, Keller GA, Steinberg D. PMID: 6406495.
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PubMed Mentions:
48 Fields:
Translation:
Animals