Objective: To evaluate whether respiratory therapy followed by the use of inhaled albuterol modif... more Objective: To evaluate whether respiratory therapy followed by the use of inhaled albuterol modifies the pulmonary deposition of inhaled tobramycin in patients with cystic fibrosis (CF) and whether pulmonary deposition correlates with disease severity or genotype. Methods: A prospective study was carried out including patients with CF older than 6 years of age and colonized with Pseudomonas aeruginosa. Exclusion criteria
We investigated the depth of systemic oscillations, as the heartbeat, always present in the optic... more We investigated the depth of systemic oscillations, as the heartbeat, always present in the optical signal. To this aim we performed measurements in the head of humans and piglets using frequency domain and time domain systems. Measurements in piglets and Monte Carlo simulations have also been used towards explaining the experimental data. Preliminary results indicate that with time and frequency domain we are able to isolate the heartbeat contribution originated from intracranial layers (brain).
This study evaluated, by clinical analysis, the hard tissue response following treatment of ligat... more This study evaluated, by clinical analysis, the hard tissue response following treatment of ligature-induced peri-implantitis defects in 5 dogs. The mandibular premolars were removed from both sides of the jaw. After 3 months of healing, two titanium implants were placed on each side of the mandible. Following abutment connection, 3 months later, experimental peri-implantitis was induced by the placement of cotton ligatures in a submarginal position. Ligatures and abutments were removed after one month and the bony defects were randomly assigned to one of the following treatments: debridement (DE), debridement plus guided bone regeneration (GBR), debridement plus mineralized bone graft (BG) and debridement plus guided bone regeneration associated with mineralized bone graft (GBR + BG). The peri-implant bone defects were clinically measured before and 5 months post-treatment. Results showed a higher percentage of vertical bone fill for GBR + BG (27.77 +/- 14.07) followed by GBR (21.7...
O aumento gengival induzido por drogas anticonvulsivantes é uma reação adversa que pode interferi... more O aumento gengival induzido por drogas anticonvulsivantes é uma reação adversa que pode interferir na erupção normal dos dentes, fonação e estética, tendo como tratamento o efetivo controle da placa dental bacteriana e a remoção de seus fatores locais de retenção, combinados ou não à excisão cirúrgica do tecido gengival. O presente trabalho tem como objetivo discutir a utilização do retalho periodontal de bisel interno como uma opção cirúrgica para o tratamento do aumento gengival induzido pela fenitoína, através da apresentação de um caso clínico que demonstra a previsibilidade da técnica empregada. UNITERMOS: aumento gengival; fenitoína; bisel interno.
O objetivo deste trabalho foi avaliar a marcação milimetrada e o diâmetro da ponta de três marcas... more O objetivo deste trabalho foi avaliar a marcação milimetrada e o diâmetro da ponta de três marcas comerciais de sondas periodontais disponíveis no mercado brasileiro (Williams-Neumar/Brasil-A; Williams-Golgran/Brasil-B e Williams-Hu-Friedy/USA-C). Para isso, foram utilizadas 94 sondas novas, sendo 50 Golgran, 35 Neumar e 9 Hu-Friedy. Imagens digitais foram obtidas, e a verificação dos parâmetros realizada através de um analisador de imagens e por um paquímetro digital (diâmetro das pontas). Os resultados demonstraram que todas as sondas obtiveram valores maiores que os padronizados. As sondas A e B, em geral, apresentam maior distorção na calibração. Foi também observado que as sondas C foram as que apresentaram medidas mais precisas, aproximando-se muito das medidas padrão e mostrando pouca variação entre os elementos da amostra.
infrared spiroximetry: noninvasive measurements of venous saturation in piglets and human subject... more infrared spiroximetry: noninvasive measurements of venous saturation in piglets and human subjects. J Appl Physiol 92: 372-384, 2002.—We present a noninvasive method to mea- sure the venous oxygen saturation (SvO2 ) in tissues using near-infrared spectroscopy (NIRS). This method is based on the respiration-induced oscillations of the near-infrared ab- sorption in tissues, and we call it spiroximetry (the prefix spiro
Device-Associated Infections Rates, Bacterial Resistance, Extra Length of stay, and Attributable Mortality in Intensive Care Units of Brazilian Hospitals. International Nosocomial Infection Control Consortium (INICC) Findings
The sequence of the Mycobacterium leprae homologue of ESAT-6 shows only 36% amino acid correspond... more The sequence of the Mycobacterium leprae homologue of ESAT-6 shows only 36% amino acid correspondence to that from Mycobacterium tuberculosis. Anti-M. leprae ESAT-6 polyclonal and monoclonal antibodies and T-cell hybridomas reacted only with the homologous protein and allowed identification of the B-and T-cell epitopes. The protein is expressed in M. leprae and appears in the cell wall fraction. Thus, M. leprae ESAT-6 shows promise as a specific diagnostic agent for leprosy. on November 7, 2017 by guest
Genetic linkage in Muir-Torre syndrome to the same chromosomal region as cancer family syndrome
European Journal of Cancer, 1994
The Muir-Torre syndrome, in which sebaceous gland tumours occur in association with internal mali... more The Muir-Torre syndrome, in which sebaceous gland tumours occur in association with internal malignancy, is inherited as an autosomal dominant disorder. Many features of the syndrome are similar to those of the Lynch II cancer family syndrome, and thus the two disorders might share a common genetic basis. We typed two large families with DNA markers on chromosome 2p around D2S123, a site recently shown to be linked to the Lynch II syndrome. LOD scores at this locus demonstrated significant and tight linkage to D2S123, suggesting that defects in the same gene might give rise to both syndromes.
Gallstones in children with sickle cell disease followed up at a Brazilian hematology center
Arquivos de Gastroenterologia, 2008
BACKGROUND: Sickle cell disease causes chronic and recurrent hemolysis which is a recognized risk... more BACKGROUND: Sickle cell disease causes chronic and recurrent hemolysis which is a recognized risk factor for cholelithiasis. This complication occurs in 50% of adults with sickle cell disease. Surgery is the consensual therapy for symptomatic patients, but the surgical approach is still controversial in asymptomatic individuals. AIMS: To determine the frequency and to describe and discuss the outcome of children with sickle cell disease complicated with gallstones followed up at a tertiary pediatric hematology center. METHODS: In a retrospective and descriptive study, 225 charts were reviewed and data regarding patient outcome were recorded. RESULTS: The prevalence of cholelithiasis was 45% and half the patients were asymptomatic. The mean age at the time of diagnosis of cholelithiasis and surgical treatment was 12.5 years (standard deviation = 5) and 14 years (standard deviation = 5.4), respectively. The prevalence of cholelithiasis was higher in patients with SS homozygous and Sb ...
The biotechnological potential of mushroom tyrosinases
Food Technology and …, 2007
... Acknowledgements Rodrigo Faria, Vivian Moure, Nadia Krieger and David Mitchell thank the Braz... more ... Acknowledgements Rodrigo Faria, Vivian Moure, Nadia Krieger and David Mitchell thank the Brazilian National Council for Scientific and Technological ... 4. C. Soler-Rivas, S. Jolivet, N. Arpin, JM Olivier, HJ Wi-chers, Biochemical and physiological aspects of brown blotch ...
Objective: To evaluate whether respiratory therapy followed by the use of inhaled albuterol modif... more Objective: To evaluate whether respiratory therapy followed by the use of inhaled albuterol modifies the pulmonary deposition of inhaled tobramycin in patients with cystic fibrosis (CF) and whether pulmonary deposition correlates with disease severity or genotype. Methods: A prospective study was carried out including patients with CF older than 6 years of age and colonized with Pseudomonas aeruginosa. Exclusion criteria
We investigated the depth of systemic oscillations, as the heartbeat, always present in the optic... more We investigated the depth of systemic oscillations, as the heartbeat, always present in the optical signal. To this aim we performed measurements in the head of humans and piglets using frequency domain and time domain systems. Measurements in piglets and Monte Carlo simulations have also been used towards explaining the experimental data. Preliminary results indicate that with time and frequency domain we are able to isolate the heartbeat contribution originated from intracranial layers (brain).
This study evaluated, by clinical analysis, the hard tissue response following treatment of ligat... more This study evaluated, by clinical analysis, the hard tissue response following treatment of ligature-induced peri-implantitis defects in 5 dogs. The mandibular premolars were removed from both sides of the jaw. After 3 months of healing, two titanium implants were placed on each side of the mandible. Following abutment connection, 3 months later, experimental peri-implantitis was induced by the placement of cotton ligatures in a submarginal position. Ligatures and abutments were removed after one month and the bony defects were randomly assigned to one of the following treatments: debridement (DE), debridement plus guided bone regeneration (GBR), debridement plus mineralized bone graft (BG) and debridement plus guided bone regeneration associated with mineralized bone graft (GBR + BG). The peri-implant bone defects were clinically measured before and 5 months post-treatment. Results showed a higher percentage of vertical bone fill for GBR + BG (27.77 +/- 14.07) followed by GBR (21.7...
O aumento gengival induzido por drogas anticonvulsivantes é uma reação adversa que pode interferi... more O aumento gengival induzido por drogas anticonvulsivantes é uma reação adversa que pode interferir na erupção normal dos dentes, fonação e estética, tendo como tratamento o efetivo controle da placa dental bacteriana e a remoção de seus fatores locais de retenção, combinados ou não à excisão cirúrgica do tecido gengival. O presente trabalho tem como objetivo discutir a utilização do retalho periodontal de bisel interno como uma opção cirúrgica para o tratamento do aumento gengival induzido pela fenitoína, através da apresentação de um caso clínico que demonstra a previsibilidade da técnica empregada. UNITERMOS: aumento gengival; fenitoína; bisel interno.
O objetivo deste trabalho foi avaliar a marcação milimetrada e o diâmetro da ponta de três marcas... more O objetivo deste trabalho foi avaliar a marcação milimetrada e o diâmetro da ponta de três marcas comerciais de sondas periodontais disponíveis no mercado brasileiro (Williams-Neumar/Brasil-A; Williams-Golgran/Brasil-B e Williams-Hu-Friedy/USA-C). Para isso, foram utilizadas 94 sondas novas, sendo 50 Golgran, 35 Neumar e 9 Hu-Friedy. Imagens digitais foram obtidas, e a verificação dos parâmetros realizada através de um analisador de imagens e por um paquímetro digital (diâmetro das pontas). Os resultados demonstraram que todas as sondas obtiveram valores maiores que os padronizados. As sondas A e B, em geral, apresentam maior distorção na calibração. Foi também observado que as sondas C foram as que apresentaram medidas mais precisas, aproximando-se muito das medidas padrão e mostrando pouca variação entre os elementos da amostra.
infrared spiroximetry: noninvasive measurements of venous saturation in piglets and human subject... more infrared spiroximetry: noninvasive measurements of venous saturation in piglets and human subjects. J Appl Physiol 92: 372-384, 2002.—We present a noninvasive method to mea- sure the venous oxygen saturation (SvO2 ) in tissues using near-infrared spectroscopy (NIRS). This method is based on the respiration-induced oscillations of the near-infrared ab- sorption in tissues, and we call it spiroximetry (the prefix spiro
Device-Associated Infections Rates, Bacterial Resistance, Extra Length of stay, and Attributable Mortality in Intensive Care Units of Brazilian Hospitals. International Nosocomial Infection Control Consortium (INICC) Findings
The sequence of the Mycobacterium leprae homologue of ESAT-6 shows only 36% amino acid correspond... more The sequence of the Mycobacterium leprae homologue of ESAT-6 shows only 36% amino acid correspondence to that from Mycobacterium tuberculosis. Anti-M. leprae ESAT-6 polyclonal and monoclonal antibodies and T-cell hybridomas reacted only with the homologous protein and allowed identification of the B-and T-cell epitopes. The protein is expressed in M. leprae and appears in the cell wall fraction. Thus, M. leprae ESAT-6 shows promise as a specific diagnostic agent for leprosy. on November 7, 2017 by guest
Genetic linkage in Muir-Torre syndrome to the same chromosomal region as cancer family syndrome
European Journal of Cancer, 1994
The Muir-Torre syndrome, in which sebaceous gland tumours occur in association with internal mali... more The Muir-Torre syndrome, in which sebaceous gland tumours occur in association with internal malignancy, is inherited as an autosomal dominant disorder. Many features of the syndrome are similar to those of the Lynch II cancer family syndrome, and thus the two disorders might share a common genetic basis. We typed two large families with DNA markers on chromosome 2p around D2S123, a site recently shown to be linked to the Lynch II syndrome. LOD scores at this locus demonstrated significant and tight linkage to D2S123, suggesting that defects in the same gene might give rise to both syndromes.
Gallstones in children with sickle cell disease followed up at a Brazilian hematology center
Arquivos de Gastroenterologia, 2008
BACKGROUND: Sickle cell disease causes chronic and recurrent hemolysis which is a recognized risk... more BACKGROUND: Sickle cell disease causes chronic and recurrent hemolysis which is a recognized risk factor for cholelithiasis. This complication occurs in 50% of adults with sickle cell disease. Surgery is the consensual therapy for symptomatic patients, but the surgical approach is still controversial in asymptomatic individuals. AIMS: To determine the frequency and to describe and discuss the outcome of children with sickle cell disease complicated with gallstones followed up at a tertiary pediatric hematology center. METHODS: In a retrospective and descriptive study, 225 charts were reviewed and data regarding patient outcome were recorded. RESULTS: The prevalence of cholelithiasis was 45% and half the patients were asymptomatic. The mean age at the time of diagnosis of cholelithiasis and surgical treatment was 12.5 years (standard deviation = 5) and 14 years (standard deviation = 5.4), respectively. The prevalence of cholelithiasis was higher in patients with SS homozygous and Sb ...
The biotechnological potential of mushroom tyrosinases
Food Technology and …, 2007
... Acknowledgements Rodrigo Faria, Vivian Moure, Nadia Krieger and David Mitchell thank the Braz... more ... Acknowledgements Rodrigo Faria, Vivian Moure, Nadia Krieger and David Mitchell thank the Brazilian National Council for Scientific and Technological ... 4. C. Soler-Rivas, S. Jolivet, N. Arpin, JM Olivier, HJ Wi-chers, Biochemical and physiological aspects of brown blotch ...
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