The wonders of the indole pulse
ZARKAN, Ashraf, et al. Indole pulse signalling regulates the cytoplasmic pH of E. coli in a memory-like manner. Scientific Reports, 2019, vol. 9, no 1, p. 1-10.
CV
You can find a link to my full CV here, but here is a briefing.
Education
- Ph.D in Medical Science, University of Cambridge (UK), (2017/Sep-2021/Nov).
- M.S. in Molecular Biology & Biotechnology, University of Groninge (NL), (2014-2016)
- B.S. Biology, Universidad Autónoma de Madrid (SP), (2008-2014)
Other training
- Advance Statistics for Data Science, John Hopkins (USA), (2022)
- Design & Interpretation Clinical Trials, John Hopkins (USA), (2022)
- B.S. Biology, Universidad Autónoma de Madrid, (2008-2014)
Research Experience
- Postdoctoral researcher, Boeck Lab (2024-Present)
- Research associate, Bryant Lab (2023-Present)
- PhD/Research associate, Floto Lab (2017-2022)
- Research assistant, Summers Lab (2016-2017)
- Student Intership, Kuipers Lab (2016)
Publications
Indole and the metabolic pathways
DE LEON-RODRIGUEZ, Antonio, et al. Indole modifies the central carbon flux in the anaerobic metabolism of Escherichia coli: application to the production of hydrogen and other metabolites. New biotechnology, 2016, vol. 33, no 6, p. 868-873.
New Approaches and Therapeutic Options for Mycobacterium tuberculosis in a Dormant State
CAÑO-MUÑIZ, Santiago, et al. New approaches and therapeutic options for Mycobacterium tuberculosis in a dormant state. Clinical microbiology reviews, 2018, vol. 31, no 1, p. e00060-17.
Persisters and pH
GOODE, Olivia, et al. Persister Escherichia coli cells have a lower intracellular pH than susceptible cells but maintain their pH in response to antibiotic treatment. MBio, 2021, vol. 12, no 4, p. e00909-21.
Ionic control of porin permeability in bacteria.
CANO MUNIZ, Santiago, et al. Ionic control of porin permeability in bacteria. bioRxiv, 2022, p. 2022.07. 13.499887.
Metabolic control of porin permeability influences antibiotic resistance in Escherichia coli.
Caño Muñiz, Santiago E., et al. "Metabolic Control of Porin Permeability Influences Antibiotic Resistance in Escherichia Coli." Nature Microbiology, vol. 10, no. 12, 2025, pp. 3202-3214, https://doi.org/10.1038/s41564-025-02175-5. Accessed 4 Dec. 2025.