PHA4GE Projects are collaborative initiatives that put genomic data standards, tools, and frameworks into practice to address high-priority pathogens and public health challenges. Each project is developed in close partnership with local, regional, and global stakeholders to ensure outputs are context-appropriate, equitable and aligned with international standards.
By focusing on real-world use cases, Driver Projects provide practical pathways for developing, testing, and refining community-driven solutions. These projects generate actionable insights for public health and serve as living examples of how interoperable standards, best practices, and governance frameworks can be applied across diverse settings.
Wastewater surveillance enables cost-effective, population-level disease monitoring. PHA4GE supports standardized and reproducible bioinformatic workflows to ensure consistent interpretation across settings. This enables integration into routine surveillance, including in resource-limited contexts.
Malaria remains a major cause of illness and death in endemic regions. Genomic epidemiology strengthens surveillance and supports targeted interventions. PHA4GE projects promote harmonized data standards to improve data sharing and regional coordination.
Mpox outbreaks highlight the need for rapid genomic surveillance. PHA4GE supports standardized sequencing and contextual data practices. These improve outbreak detection and public health response.
AMR threatens effective treatment and health system resilience. PHA4GE projects enable harmonized genomic surveillance and standardized interpretation of resistance markers. This supports national AMR action plans and public health decision-making.
Cholera causes recurrent outbreaks in vulnerable populations. Genomic tools strengthen surveillance and outbreak response. PHA4GE promotes standardized data practices to improve comparability and coordination.
Sepsis, including neonatal sepsis, remains a leading cause of mortality. Genomic epidemiology and AMR profiling improve pathogen identification. PHA4GE supports scalable data standards to inform surveillance and clinical decision-making.
Meningitis outbreaks cause high mortality and long-term disability. Genomic epidemiology improves early detection and response. PHA4GE supports standardized data frameworks to strengthen surveillance.
coming soon
Coming soon.
Equitable data sharing and accessible repositories are essential to unlocking the full potential of microbial genomics for public health.
During the COVID-19 pandemic, PHA4GE enabled global genomic surveillance through rapid standards development. These efforts improved data sharing and interoperability. Lessons learned now inform surveillance for other priority pathogens.
Additional initiatives and miscellaneous efforts that support PHA4GE’s mission
PHA4GE also undertakes complementary initiatives, including capacity building, method development, and work on data governance and equity.
Work with PHA4GE to strengthen genomic surveillance and public health systems worldwide. Join a Driver Project to contribute expertise, collaborate with global partners, and support data-driven public health action.
PHA4GE works with partners who share our commitment to improving coordination, data-driven decision-making, and preparedness for disease outbreaks.
We invite organisations, institutions, and funders to connect with us and help shape the future of global public health.