Background Gastric polyps are often detected incidentally during endoscopic procedures performed ... more Background Gastric polyps are often detected incidentally during endoscopic procedures performed for different reasons and may sometimes manifest by gastric bleeding, pyloric stenosis, iron deficiency anemia and abdominal pain. Our study aimed to investigate the demographic data of the cases found to have gastric polyps at the gastroenterology endoscopy unit, histologic type of the polyps, their localization and size, and their relationship with Helicobacter pylori. Material and Methods Between September 2016-September 2019, gastric polyps were detected in 255 of 9,771 cases who underwent upper gastrointestinal system endoscopy at the Gastroenterology Endoscopy Unit of our hospital. Demographic data, endoscopy reports and pathology results of these patients were retrospectively reviewed from the hospital registry system. Results Of 255 cases included in the study, 160 (62.7%) were female, and 95 (37.3%) were male, with a mean age of 56.9 (min: 19, max: 95). A total of 336 polyps were detected in 255 cases, with 1.3 polyps per case. 36 (10.7%) of gastric polyps were found to be fundic gland polyps, 32 (9.5%) were found to be foveolar hyperplasia, 137 (40.8%) were found to be hyperplastic polyps, 5 (1.5%) were found to be xanthomas, and 6 (1.8%) were found to be neuroendocrine tumors. Conclusions According to this study, 90% of gastric polyps detected endoscopically in southeast Turkey are smaller than 5 mm and located most commonly in the corpus; the most common histologic subtype is hyperplastic polyps.
Objective: The aim of this study was to evaluate the effect of the euthyroid nodular gouiter on t... more Objective: The aim of this study was to evaluate the effect of the euthyroid nodular gouiter on the anxiety and depression. Materials and Methods: 50 male and 50 female patients between ages of 18-50 who were diagnosed euthyroid nodular gouiter for at least 6 months were included in our study (group 2). 20 male and 20 female healthy patients were included as control group (group 1). The patients who had psychiatric problems and chronic comorbidities were excluded. The BDS (Beck Depression scale) and BAS (Beck anxiety scale) tests were used as comparison of two groups. Student's T-test was performed for parametric data A p level of <0.05 was taken as statistically significant. Results: Comparing the unhealthy and control groups: BDS test and BAS test were significantly higher in group 2 male patients than group 1 male patients, p=0.019 and p<0.005 respectively. Group 2 female patients showed significantly higher results in BDS and BAS tests than group 1 female patients, p<0.001 and p<0.001 respectively. Conclusion: The result of this study showed that euthyroid nodular gouiter had negative effects on anxiety and depression and our article is the first article in literature on this issue.
Aim: Diabetic dermopathy is a skin disease, seen in patients with diabetes mellitus, characterize... more Aim: Diabetic dermopathy is a skin disease, seen in patients with diabetes mellitus, characterized by atrophic scar and hyperpigmented lesions. Recently, it was proposed that this disease might be associated with other microangiopathic complications of diabetes such as retinopathy, nephropathy, and polyneuropathy. In this study, patients with diabetic dermopathy were compared with two control groups to test the validity of these associations. Material and Methods: Twenty-three patients, who admitted to Dermatology Outpatient Clinic Health Sciences University Gazi Yaşargil Education and Research Hospital and diagnosed as diabetic dermopathy were included in the study. Twenty-three patients with well controlled diabetes mellitus (Control Group A) who treated as outpatients and 23 patients with diabetes mellitus who had poor general status and hospitalized by internal medicine department (Control Group B) were included as two control groups. Patients were evaluated in terms of retinopa...
Background: Rabies is among the infections which has the highest fatality rate among all other in... more Background: Rabies is among the infections which has the highest fatality rate among all other inflectional diseases. In our study we aimed to predict the precautions to be taken and review demographic characteristics of the cases that apply to Batman Regional State Hospital Emergency Service Rabies Unit. Method: In our study between January 2012 – January 2017, 1591 patients have been examined retrospectively who apply to Batman Regional State Hospital Emergency Rabies Unit. Ages, genders, residential locations (urban/rural centers), whether the animal is a waif or reverse, species, wound location, whether the physical injury is deep or surficial, type of contact and application period after contact, whether prophylaxis is applied to the bitten patient or not and the season of contact of cases have been taken under registration. Results: In our study average ages of our 1591 cases was 22,73 ± 17,20. 77,9% (n=1239) of cases were male and 22,1% (n=352) of cases were female and 70,3% ...
Asian Journal of Biomedical and Pharmaceutical Sciences, 2017
Objective: Chronic Sinusitis, as per symptoms, is a disease that has been associated with depress... more Objective: Chronic Sinusitis, as per symptoms, is a disease that has been associated with depression and anxiety in nominal literature. In the literature, regardless of symptoms, the impact of anxiety and depression on patients with a diagnosis of chronic rhinosinusitis is an issue which has not been explained much. In this study we have tried to clarify this subject. Materials and methods: Our study was designed as a prospective study. The group has been formed by including 50 male and 50 female patients aged between 20 and 40 (group 1) and 30 male and 30 female control groups to this study (group 2). Patients and control groups were given BDI (Beck Depression Inventory) and BAI (Beck Anxiety Inventory) to be filled, then the total point averages they received and the number of patients who received over cut off values was compared separately in male and female in group 1 and 2 by SPSS and t-test. Results: In men, while the average total scores received from BDI were 10 ± 7 in Grou...
Aim: Rhabdomyolysis (RML) is a clinical and biochemical syndrome caused by acute necrosis of stri... more Aim: Rhabdomyolysis (RML) is a clinical and biochemical syndrome caused by acute necrosis of striated muscle fibers and the subsequent transportation of potentially toxic cellular contents into the systemic circulation. In this study, we present data from rhabdomyolysis patients that developed acute renal failure who were hospitalized and treated in our clinic in 2019. Materials and Methods: We reviewed all cases of RML treated in the tertiary hospital within a 12-month period, which was defined as serum creatinine kinase (CK) levels > five times the upper normal limit. The inclusion criteria were as follow: (a) being aged ≥ 18 years, (b) being treated for RML within the designated time period, (c) AKI development. The exclusion criteria are as follows: (a) being aged <18 years, (b) patients without AKI, (c) patients with End Stage Renal Disease(ESRD), (d) patients with neuromuscular diseases. Among a total of 583 patients with CK > 5 time upper normal limit (UNL), 14 confo...
OBJECTIVE Although dual-energy x-ray absorptiometry (DXA) remains the gold standard for the measu... more OBJECTIVE Although dual-energy x-ray absorptiometry (DXA) remains the gold standard for the measurement of bone mineral density (BMD), degenerative spine and spinal instrumentation yields inaccurate results, warranting the need for optional methods. METHODS Surgical options depend on the BMD of the patients, and to accommodate this need, we compared Hounsfield unit (HU) measurements obtained from computed tomography (CT) scans with the T-scores obtained from DXA scans to inquire whether HU measurements can screen for BMD. In this study, we also evaluated the relationship between body mass index and spontaneous fractures. RESULTS Based on the findings described in this study, we provide evidence that HU measurements obtained from CT scans can predict BMD. CONCLUSIONS This, therefore, allows HU measurements to be used as an effective diagnostic method in lieu of DXA scans when deciding on appropriate management of therapy for patients with spinal instrumentation or degenerative spines.
Ferit Akıl1, Eşref Araç2, Ayhan Kaydu3, Muhammed Ayral4, Serkan Dedeoğlu4, Erhan Gökçek3, Ahmet Ü... more Ferit Akıl1, Eşref Araç2, Ayhan Kaydu3, Muhammed Ayral4, Serkan Dedeoğlu4, Erhan Gökçek3, Ahmet Üzer5, Bilal Hamarat6 1Diyarbakır Selahaddin Eyyubi Devlet Hastanesi Kulak Burun Boğaz Kliniği, Türkiye 2Gazi Yaşargil Eğitim Araştırma Hastanesi Dahiliye Kliniği, Diyarbakır, Türkiye 3Diyarbakır Selahaddin Eyyubi Devlet Hastanesi Anestezi kliniği, Diyarbakır, Türkiye 4Gazi Yaşargil Eğitim Araştırma Hastanesi Kulak Burun Boğaz Kliniği, Diyarbakır, Türkiye 5Çorum Eğitim Araştırma Hastanesi Psikiyatri Kliniği, Çorum, Türkiye 6Artvin Devlet Hastanesi Üroloji Kliniği, Artvin, Türkiye
Enfeksiyon kontrolü özellikle başta yoğun bakım üniteleri (YBÜ) olmak üzere hastaneler için öncel... more Enfeksiyon kontrolü özellikle başta yoğun bakım üniteleri (YBÜ) olmak üzere hastaneler için öncelikli bir hedeftir. YBÜ'de dünya çapında yaygınlık oranı %30 olarak tahmin edilen enfeksiyonlar önemli bir morbidite ve mortalite nedenidir. Yoğun bakımda yatan hastalarda enfeksiyon riskini artıran pek çok
This study was approved by the ethics committee of Gazi Yaşargil Education and Research Hospital ... more This study was approved by the ethics committee of Gazi Yaşargil Education and Research Hospital with the decision numbered 452 and dated April 28, 2020. All procedures in this study involving human participants were performed in accordance with the 1964 Helsinki Declaration and its later amendments.
Background: Mastalgia defines pain that is located in or felt in the breast area. Pain can be a s... more Background: Mastalgia defines pain that is located in or felt in the breast area. Pain can be a symptom in many psychiatric disorders. Therefore, considering the psychiatric disorders in the evaluation of patients with mastalgia is of great importance in terms of treatment success and pain control Aims and Objective: In this study, we aimed to identify the psychiatric diagnoses that may be involved in the etiology of mastalgia and to retrospectively determine the frequency of patients who may need psychiatric treatment among the treatment options that can be used in patients with mastalgia Materials and Methods: We included patients who presented with breast pain between August 2017 and August 2018 and had normal results of radiological imaging studies. The archive system of the hospital was screened for the presence of any psychiatric admission before the diagnosis and previous psychiatric diagnoses, if any, were recorded Results: There were 1124 patients with mastalgia included in...
Aim: Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), mean platelet volume (MP... more Aim: Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), mean platelet volume (MPV) and erythrocyte distribution width (RDW) are considered to be associated with systemic inflammation. In this study, it was aimed to evaluate NLR, PLR, MPV and RDW as prognostic factors in acute pancreatitis (AP). : A total of 315 patients admitted to Health Sciences University Gazi Yaşargil Training and Research Hospital between May 2016 and May 2019 and diagnosed with AP were included in the study. Data of the patients were analyzed retrospectively. Laboratory values of the patients at the time of admission to the hospital were recorded and the Ranson score was calculated. Patients were divided into two groups as Ranson score <3 (mild AP) and ≥3 (severe AP). NLR, PLR, MPV and RDW parameters were compared between these groups. Results: Of the patients, 103 (32.7%) were males and 212 (67.3%) were females, and mean age was 57.2±19.5. According to the Ranson criteria, number of patients with a score below 3 was 274 (87.0%), and number of patients with a score of 3 or above was 41 (13.0%). In the severe AP group, NLR and PLR were significantly higher than in the mild AP group (16.2±14.3 vs. 8.2±7.7, p<0.001 and 283.7±223.0 vs. 195.5±139.3, p=0.004 respectively), but there was no statistically significant difference in terms of RDW-CV and MPV (13.7±1.0 vs. 13.9±1.9, p=0.849 and 9.7±1.3 vs. 9.5±1.1, p=0.201, respectively). Conclusion: NLR and PLR are simple and safe tests that can be used to determine the severity of AP.
The aim of this study was to determine the effect of vitamin D (vit D) supplementation on the ocu... more The aim of this study was to determine the effect of vitamin D (vit D) supplementation on the ocular surface parameters in patients with vit D deficiency. Material and Methods: In total, 63 patients with serum vit D deficiency were included. Patients were treated with an oral dose of 300.000 IU cholecalciferol. The ocular surface disease index (OSDI) questionnaire, fluorescein tears breakup time (FBUT), Oxford score, and Schirmer's 1 test were performed for all patients. The data was obtained initially and at 4, 8, and 12 weeks after vit D supplementation. Results: Forty-nine of the patients were female and 14 were male. The mean age was 30.8±9.7 (18-58) years. All 63 patients came to the first follow-up, 57 patients came to the second follow-up, and 48 patients came to the third follow-up. The OSDI and Oxford scores yielded statistically significant decreases, while Schirmer's 1 test and FBUT values showed a statistically significant increase after treatment with vit D. A positive correlation was observed between vit D values and FBUT and Schirmer's 1 values; there was a negative correlation between OSDI values (r=0.286 and p<0.001, r=0.219 and p=0.032, r =-0.357 and p<0.001, respectively). The dry eye findings improved significantly after vit D supplementation in all cases. Conclusion: During clinical follow-up, it is important to evaluate serum vit D levels in patients with dry eye syndrome (DES). Increasing their vit D levels will help clinicians to treat DES quickly and effectively.
Abstract Background It is seen that various forms of retinoids have different results on VEGF-A a... more Abstract Background It is seen that various forms of retinoids have different results on VEGF-A and VEGF-C levels when tested at different dosages, in different diseases and under different conditions such as in vivo or in vitro. Objective To evaluate the effects of isotretinoin on VEGF-A and VEGF-C levels in humans. Methods Blood samples at the third month of the patient group and blood samples of the control group were compared in terms of VEGF-A and VEGF-C concentrations. Results No statistically significant difference was observed between the patient group and the control group in terms of VEGF-A and VEGF-C levels. Limitations Most of the patients discontinued treatment and could not reach the required number, the study was converted to case–control. Conclusions We think that 0.5 mg/kg/day isotretinoin has no effect on blood concentrations of VEGF-A and VEGF-C in humans. Therefore, there is a need for studies using isotretinoin in different doses and durations in humans in order to better evaluate its effects.
International Journal of Hematology and Oncology, 2020
We aimed to investigate whether there is a predisposition to COVID-19 with ABO and Rh blood group... more We aimed to investigate whether there is a predisposition to COVID-19 with ABO and Rh blood group systems. This study was a retrospective study that investigate the patients admitted to our hospital between March 16-May 20 due to Covid-19 pandemic and conducted with data revealed from the hospital Information Management System A total of 392 patients were included in this study, including 227 PCR test positive patients with blood group information in the system and 165 possible patients with CT findings in favor of Covid-19. Data from a blood group study conducted with 127091 people in our province in 2019 were used as a control group. In our study, a significant increase was observed in the blood group A in patients diagnosed with Covid-19, and a decrease was found in the blood groups B, AB and especially O. However, statistical analysis showed no significant difference between Covid-19 patients and healthy individuals in terms of ABO blood group system. When analyzed in terms of Rh blood group system, it was found that Rh positivity was statistically significantly higher in patients with Covid-19 (p= 0.000). Our study suggests that the Rh (-) blood group is protective and the Rh (+) blood group is predisposed to Covid 19 significantly. We think that it is valuable because it is the first study to reveal the relationship between Covid-19 and blood type in our country and the only one to reveal the relationship between Covid-19 and Rh (+) in the world literature.
CLINICAL RELEVANCE Obesity has become one of the most important health problems of today with its... more CLINICAL RELEVANCE Obesity has become one of the most important health problems of today with its increasing prevalence. With the development of retinal imaging systems, obesity has been observed to be associated with changes in outer retinal layers and choroid in women. BACKGROUND The aim of this study was to examine retinal layer parameters and their relationship with body mass index in obese women. METHODS The study included 197 eyes of 197 women, of whom 44 were normal-weight, 40 were overweight, 40 were class 1 obese, 38 were class 2 obese, and 35 were morbidly obese. The thickness of the choroid was measured manually using an enhanced-depth imaging optical coherence tomography scanning program. RESULTS The mean choroidal thickness values in five locations were lower than those of normal-weight, overweight, class 1, and class 2 obese women, in morbidly obese women (p < 0.05 for all). Subfoveal outer retinal layer thickness and specific sublayer thickness of the photoreceptor layer values were significantly lower in morbidly obese women than in normal-weight women, but there were no statistically significant differences between the groups in retinal pigment epithelium thickness and Bruch's membrane thickness (p = 0.001, p < 0.001, p = 1.00, and p = 0.101, respectively). Furthermore, there were significant negative relationships between body mass index and subfoveal choroidal thickness, subfoveal outer retinal layer thickness, and specific sublayer thickness of the photoreceptor layer values (r = -0.327, p < 0.001; r = -0.259, p < 0.001; and r = -0.281, p < 0.001, respectively). CONCLUSIONS Morbid obesity was associated with a thinner choroid, subfoveal outer retinal layer, and specific sublayer thickness of the photoreceptor layer in women. Furthermore, retinal hypoxia associated with morbid obesity may be related to a decrease in photoreceptor layer thickness. Thinning of the outer retinal layer may also lead to atrophy of the cone sheath.
Medical Journal of Islamic World Academy of Sciences, 2017
Chronic/recurrent tonsillitis is a condition that affects the quality of life with symptoms such ... more Chronic/recurrent tonsillitis is a condition that affects the quality of life with symptoms such as pain, fever, halitosis, and so forth. However, the effect of this condition on depression and anxiety has not been studied. Therefore, this study aimed to investigate the complex relationship between chronic/recurrent tonsillitis and depression and anxiety in adult patients. The study included 60 female and 60 male patients and 25 healthy male and 25 healthy female controls, aged 18-40 years. The participants were made to fill out the Beck depression and anxiety inventories (BDI and BAI). Those who met the inclusion criteria were included. The averages and cutoff values of the total scores were investigated separately for males and females. For both males and females, the averages of total BDI scores (P < 0.043 and <0.035, respectively) and total BAI scores (P = 0.019 and 0.027, respectively) were significantly higher in group 2 than in group 1. This study was novel in exploring the relationship between chronic/recurrent tonsillitis and depression and anxiety in adults. The findings of this study might enhance the understanding on this subject and serve as a valuable guidance for the interested researchers.
Araştırmamız daha önce bilimsel bir toplantıda sunulmamıştır. Çalısmamızı destekleyen kurum veya ... more Araştırmamız daha önce bilimsel bir toplantıda sunulmamıştır. Çalısmamızı destekleyen kurum veya kuruluş yoktur.
Background Gastric polyps are often detected incidentally during endoscopic procedures performed ... more Background Gastric polyps are often detected incidentally during endoscopic procedures performed for different reasons and may sometimes manifest by gastric bleeding, pyloric stenosis, iron deficiency anemia and abdominal pain. Our study aimed to investigate the demographic data of the cases found to have gastric polyps at the gastroenterology endoscopy unit, histologic type of the polyps, their localization and size, and their relationship with Helicobacter pylori. Material and Methods Between September 2016-September 2019, gastric polyps were detected in 255 of 9,771 cases who underwent upper gastrointestinal system endoscopy at the Gastroenterology Endoscopy Unit of our hospital. Demographic data, endoscopy reports and pathology results of these patients were retrospectively reviewed from the hospital registry system. Results Of 255 cases included in the study, 160 (62.7%) were female, and 95 (37.3%) were male, with a mean age of 56.9 (min: 19, max: 95). A total of 336 polyps were detected in 255 cases, with 1.3 polyps per case. 36 (10.7%) of gastric polyps were found to be fundic gland polyps, 32 (9.5%) were found to be foveolar hyperplasia, 137 (40.8%) were found to be hyperplastic polyps, 5 (1.5%) were found to be xanthomas, and 6 (1.8%) were found to be neuroendocrine tumors. Conclusions According to this study, 90% of gastric polyps detected endoscopically in southeast Turkey are smaller than 5 mm and located most commonly in the corpus; the most common histologic subtype is hyperplastic polyps.
Objective: The aim of this study was to evaluate the effect of the euthyroid nodular gouiter on t... more Objective: The aim of this study was to evaluate the effect of the euthyroid nodular gouiter on the anxiety and depression. Materials and Methods: 50 male and 50 female patients between ages of 18-50 who were diagnosed euthyroid nodular gouiter for at least 6 months were included in our study (group 2). 20 male and 20 female healthy patients were included as control group (group 1). The patients who had psychiatric problems and chronic comorbidities were excluded. The BDS (Beck Depression scale) and BAS (Beck anxiety scale) tests were used as comparison of two groups. Student's T-test was performed for parametric data A p level of <0.05 was taken as statistically significant. Results: Comparing the unhealthy and control groups: BDS test and BAS test were significantly higher in group 2 male patients than group 1 male patients, p=0.019 and p<0.005 respectively. Group 2 female patients showed significantly higher results in BDS and BAS tests than group 1 female patients, p<0.001 and p<0.001 respectively. Conclusion: The result of this study showed that euthyroid nodular gouiter had negative effects on anxiety and depression and our article is the first article in literature on this issue.
Aim: Diabetic dermopathy is a skin disease, seen in patients with diabetes mellitus, characterize... more Aim: Diabetic dermopathy is a skin disease, seen in patients with diabetes mellitus, characterized by atrophic scar and hyperpigmented lesions. Recently, it was proposed that this disease might be associated with other microangiopathic complications of diabetes such as retinopathy, nephropathy, and polyneuropathy. In this study, patients with diabetic dermopathy were compared with two control groups to test the validity of these associations. Material and Methods: Twenty-three patients, who admitted to Dermatology Outpatient Clinic Health Sciences University Gazi Yaşargil Education and Research Hospital and diagnosed as diabetic dermopathy were included in the study. Twenty-three patients with well controlled diabetes mellitus (Control Group A) who treated as outpatients and 23 patients with diabetes mellitus who had poor general status and hospitalized by internal medicine department (Control Group B) were included as two control groups. Patients were evaluated in terms of retinopa...
Background: Rabies is among the infections which has the highest fatality rate among all other in... more Background: Rabies is among the infections which has the highest fatality rate among all other inflectional diseases. In our study we aimed to predict the precautions to be taken and review demographic characteristics of the cases that apply to Batman Regional State Hospital Emergency Service Rabies Unit. Method: In our study between January 2012 – January 2017, 1591 patients have been examined retrospectively who apply to Batman Regional State Hospital Emergency Rabies Unit. Ages, genders, residential locations (urban/rural centers), whether the animal is a waif or reverse, species, wound location, whether the physical injury is deep or surficial, type of contact and application period after contact, whether prophylaxis is applied to the bitten patient or not and the season of contact of cases have been taken under registration. Results: In our study average ages of our 1591 cases was 22,73 ± 17,20. 77,9% (n=1239) of cases were male and 22,1% (n=352) of cases were female and 70,3% ...
Asian Journal of Biomedical and Pharmaceutical Sciences, 2017
Objective: Chronic Sinusitis, as per symptoms, is a disease that has been associated with depress... more Objective: Chronic Sinusitis, as per symptoms, is a disease that has been associated with depression and anxiety in nominal literature. In the literature, regardless of symptoms, the impact of anxiety and depression on patients with a diagnosis of chronic rhinosinusitis is an issue which has not been explained much. In this study we have tried to clarify this subject. Materials and methods: Our study was designed as a prospective study. The group has been formed by including 50 male and 50 female patients aged between 20 and 40 (group 1) and 30 male and 30 female control groups to this study (group 2). Patients and control groups were given BDI (Beck Depression Inventory) and BAI (Beck Anxiety Inventory) to be filled, then the total point averages they received and the number of patients who received over cut off values was compared separately in male and female in group 1 and 2 by SPSS and t-test. Results: In men, while the average total scores received from BDI were 10 ± 7 in Grou...
Aim: Rhabdomyolysis (RML) is a clinical and biochemical syndrome caused by acute necrosis of stri... more Aim: Rhabdomyolysis (RML) is a clinical and biochemical syndrome caused by acute necrosis of striated muscle fibers and the subsequent transportation of potentially toxic cellular contents into the systemic circulation. In this study, we present data from rhabdomyolysis patients that developed acute renal failure who were hospitalized and treated in our clinic in 2019. Materials and Methods: We reviewed all cases of RML treated in the tertiary hospital within a 12-month period, which was defined as serum creatinine kinase (CK) levels > five times the upper normal limit. The inclusion criteria were as follow: (a) being aged ≥ 18 years, (b) being treated for RML within the designated time period, (c) AKI development. The exclusion criteria are as follows: (a) being aged <18 years, (b) patients without AKI, (c) patients with End Stage Renal Disease(ESRD), (d) patients with neuromuscular diseases. Among a total of 583 patients with CK > 5 time upper normal limit (UNL), 14 confo...
OBJECTIVE Although dual-energy x-ray absorptiometry (DXA) remains the gold standard for the measu... more OBJECTIVE Although dual-energy x-ray absorptiometry (DXA) remains the gold standard for the measurement of bone mineral density (BMD), degenerative spine and spinal instrumentation yields inaccurate results, warranting the need for optional methods. METHODS Surgical options depend on the BMD of the patients, and to accommodate this need, we compared Hounsfield unit (HU) measurements obtained from computed tomography (CT) scans with the T-scores obtained from DXA scans to inquire whether HU measurements can screen for BMD. In this study, we also evaluated the relationship between body mass index and spontaneous fractures. RESULTS Based on the findings described in this study, we provide evidence that HU measurements obtained from CT scans can predict BMD. CONCLUSIONS This, therefore, allows HU measurements to be used as an effective diagnostic method in lieu of DXA scans when deciding on appropriate management of therapy for patients with spinal instrumentation or degenerative spines.
Ferit Akıl1, Eşref Araç2, Ayhan Kaydu3, Muhammed Ayral4, Serkan Dedeoğlu4, Erhan Gökçek3, Ahmet Ü... more Ferit Akıl1, Eşref Araç2, Ayhan Kaydu3, Muhammed Ayral4, Serkan Dedeoğlu4, Erhan Gökçek3, Ahmet Üzer5, Bilal Hamarat6 1Diyarbakır Selahaddin Eyyubi Devlet Hastanesi Kulak Burun Boğaz Kliniği, Türkiye 2Gazi Yaşargil Eğitim Araştırma Hastanesi Dahiliye Kliniği, Diyarbakır, Türkiye 3Diyarbakır Selahaddin Eyyubi Devlet Hastanesi Anestezi kliniği, Diyarbakır, Türkiye 4Gazi Yaşargil Eğitim Araştırma Hastanesi Kulak Burun Boğaz Kliniği, Diyarbakır, Türkiye 5Çorum Eğitim Araştırma Hastanesi Psikiyatri Kliniği, Çorum, Türkiye 6Artvin Devlet Hastanesi Üroloji Kliniği, Artvin, Türkiye
Enfeksiyon kontrolü özellikle başta yoğun bakım üniteleri (YBÜ) olmak üzere hastaneler için öncel... more Enfeksiyon kontrolü özellikle başta yoğun bakım üniteleri (YBÜ) olmak üzere hastaneler için öncelikli bir hedeftir. YBÜ'de dünya çapında yaygınlık oranı %30 olarak tahmin edilen enfeksiyonlar önemli bir morbidite ve mortalite nedenidir. Yoğun bakımda yatan hastalarda enfeksiyon riskini artıran pek çok
This study was approved by the ethics committee of Gazi Yaşargil Education and Research Hospital ... more This study was approved by the ethics committee of Gazi Yaşargil Education and Research Hospital with the decision numbered 452 and dated April 28, 2020. All procedures in this study involving human participants were performed in accordance with the 1964 Helsinki Declaration and its later amendments.
Background: Mastalgia defines pain that is located in or felt in the breast area. Pain can be a s... more Background: Mastalgia defines pain that is located in or felt in the breast area. Pain can be a symptom in many psychiatric disorders. Therefore, considering the psychiatric disorders in the evaluation of patients with mastalgia is of great importance in terms of treatment success and pain control Aims and Objective: In this study, we aimed to identify the psychiatric diagnoses that may be involved in the etiology of mastalgia and to retrospectively determine the frequency of patients who may need psychiatric treatment among the treatment options that can be used in patients with mastalgia Materials and Methods: We included patients who presented with breast pain between August 2017 and August 2018 and had normal results of radiological imaging studies. The archive system of the hospital was screened for the presence of any psychiatric admission before the diagnosis and previous psychiatric diagnoses, if any, were recorded Results: There were 1124 patients with mastalgia included in...
Aim: Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), mean platelet volume (MP... more Aim: Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), mean platelet volume (MPV) and erythrocyte distribution width (RDW) are considered to be associated with systemic inflammation. In this study, it was aimed to evaluate NLR, PLR, MPV and RDW as prognostic factors in acute pancreatitis (AP). : A total of 315 patients admitted to Health Sciences University Gazi Yaşargil Training and Research Hospital between May 2016 and May 2019 and diagnosed with AP were included in the study. Data of the patients were analyzed retrospectively. Laboratory values of the patients at the time of admission to the hospital were recorded and the Ranson score was calculated. Patients were divided into two groups as Ranson score <3 (mild AP) and ≥3 (severe AP). NLR, PLR, MPV and RDW parameters were compared between these groups. Results: Of the patients, 103 (32.7%) were males and 212 (67.3%) were females, and mean age was 57.2±19.5. According to the Ranson criteria, number of patients with a score below 3 was 274 (87.0%), and number of patients with a score of 3 or above was 41 (13.0%). In the severe AP group, NLR and PLR were significantly higher than in the mild AP group (16.2±14.3 vs. 8.2±7.7, p<0.001 and 283.7±223.0 vs. 195.5±139.3, p=0.004 respectively), but there was no statistically significant difference in terms of RDW-CV and MPV (13.7±1.0 vs. 13.9±1.9, p=0.849 and 9.7±1.3 vs. 9.5±1.1, p=0.201, respectively). Conclusion: NLR and PLR are simple and safe tests that can be used to determine the severity of AP.
The aim of this study was to determine the effect of vitamin D (vit D) supplementation on the ocu... more The aim of this study was to determine the effect of vitamin D (vit D) supplementation on the ocular surface parameters in patients with vit D deficiency. Material and Methods: In total, 63 patients with serum vit D deficiency were included. Patients were treated with an oral dose of 300.000 IU cholecalciferol. The ocular surface disease index (OSDI) questionnaire, fluorescein tears breakup time (FBUT), Oxford score, and Schirmer's 1 test were performed for all patients. The data was obtained initially and at 4, 8, and 12 weeks after vit D supplementation. Results: Forty-nine of the patients were female and 14 were male. The mean age was 30.8±9.7 (18-58) years. All 63 patients came to the first follow-up, 57 patients came to the second follow-up, and 48 patients came to the third follow-up. The OSDI and Oxford scores yielded statistically significant decreases, while Schirmer's 1 test and FBUT values showed a statistically significant increase after treatment with vit D. A positive correlation was observed between vit D values and FBUT and Schirmer's 1 values; there was a negative correlation between OSDI values (r=0.286 and p<0.001, r=0.219 and p=0.032, r =-0.357 and p<0.001, respectively). The dry eye findings improved significantly after vit D supplementation in all cases. Conclusion: During clinical follow-up, it is important to evaluate serum vit D levels in patients with dry eye syndrome (DES). Increasing their vit D levels will help clinicians to treat DES quickly and effectively.
Abstract Background It is seen that various forms of retinoids have different results on VEGF-A a... more Abstract Background It is seen that various forms of retinoids have different results on VEGF-A and VEGF-C levels when tested at different dosages, in different diseases and under different conditions such as in vivo or in vitro. Objective To evaluate the effects of isotretinoin on VEGF-A and VEGF-C levels in humans. Methods Blood samples at the third month of the patient group and blood samples of the control group were compared in terms of VEGF-A and VEGF-C concentrations. Results No statistically significant difference was observed between the patient group and the control group in terms of VEGF-A and VEGF-C levels. Limitations Most of the patients discontinued treatment and could not reach the required number, the study was converted to case–control. Conclusions We think that 0.5 mg/kg/day isotretinoin has no effect on blood concentrations of VEGF-A and VEGF-C in humans. Therefore, there is a need for studies using isotretinoin in different doses and durations in humans in order to better evaluate its effects.
International Journal of Hematology and Oncology, 2020
We aimed to investigate whether there is a predisposition to COVID-19 with ABO and Rh blood group... more We aimed to investigate whether there is a predisposition to COVID-19 with ABO and Rh blood group systems. This study was a retrospective study that investigate the patients admitted to our hospital between March 16-May 20 due to Covid-19 pandemic and conducted with data revealed from the hospital Information Management System A total of 392 patients were included in this study, including 227 PCR test positive patients with blood group information in the system and 165 possible patients with CT findings in favor of Covid-19. Data from a blood group study conducted with 127091 people in our province in 2019 were used as a control group. In our study, a significant increase was observed in the blood group A in patients diagnosed with Covid-19, and a decrease was found in the blood groups B, AB and especially O. However, statistical analysis showed no significant difference between Covid-19 patients and healthy individuals in terms of ABO blood group system. When analyzed in terms of Rh blood group system, it was found that Rh positivity was statistically significantly higher in patients with Covid-19 (p= 0.000). Our study suggests that the Rh (-) blood group is protective and the Rh (+) blood group is predisposed to Covid 19 significantly. We think that it is valuable because it is the first study to reveal the relationship between Covid-19 and blood type in our country and the only one to reveal the relationship between Covid-19 and Rh (+) in the world literature.
CLINICAL RELEVANCE Obesity has become one of the most important health problems of today with its... more CLINICAL RELEVANCE Obesity has become one of the most important health problems of today with its increasing prevalence. With the development of retinal imaging systems, obesity has been observed to be associated with changes in outer retinal layers and choroid in women. BACKGROUND The aim of this study was to examine retinal layer parameters and their relationship with body mass index in obese women. METHODS The study included 197 eyes of 197 women, of whom 44 were normal-weight, 40 were overweight, 40 were class 1 obese, 38 were class 2 obese, and 35 were morbidly obese. The thickness of the choroid was measured manually using an enhanced-depth imaging optical coherence tomography scanning program. RESULTS The mean choroidal thickness values in five locations were lower than those of normal-weight, overweight, class 1, and class 2 obese women, in morbidly obese women (p < 0.05 for all). Subfoveal outer retinal layer thickness and specific sublayer thickness of the photoreceptor layer values were significantly lower in morbidly obese women than in normal-weight women, but there were no statistically significant differences between the groups in retinal pigment epithelium thickness and Bruch's membrane thickness (p = 0.001, p < 0.001, p = 1.00, and p = 0.101, respectively). Furthermore, there were significant negative relationships between body mass index and subfoveal choroidal thickness, subfoveal outer retinal layer thickness, and specific sublayer thickness of the photoreceptor layer values (r = -0.327, p < 0.001; r = -0.259, p < 0.001; and r = -0.281, p < 0.001, respectively). CONCLUSIONS Morbid obesity was associated with a thinner choroid, subfoveal outer retinal layer, and specific sublayer thickness of the photoreceptor layer in women. Furthermore, retinal hypoxia associated with morbid obesity may be related to a decrease in photoreceptor layer thickness. Thinning of the outer retinal layer may also lead to atrophy of the cone sheath.
Medical Journal of Islamic World Academy of Sciences, 2017
Chronic/recurrent tonsillitis is a condition that affects the quality of life with symptoms such ... more Chronic/recurrent tonsillitis is a condition that affects the quality of life with symptoms such as pain, fever, halitosis, and so forth. However, the effect of this condition on depression and anxiety has not been studied. Therefore, this study aimed to investigate the complex relationship between chronic/recurrent tonsillitis and depression and anxiety in adult patients. The study included 60 female and 60 male patients and 25 healthy male and 25 healthy female controls, aged 18-40 years. The participants were made to fill out the Beck depression and anxiety inventories (BDI and BAI). Those who met the inclusion criteria were included. The averages and cutoff values of the total scores were investigated separately for males and females. For both males and females, the averages of total BDI scores (P < 0.043 and <0.035, respectively) and total BAI scores (P = 0.019 and 0.027, respectively) were significantly higher in group 2 than in group 1. This study was novel in exploring the relationship between chronic/recurrent tonsillitis and depression and anxiety in adults. The findings of this study might enhance the understanding on this subject and serve as a valuable guidance for the interested researchers.
Araştırmamız daha önce bilimsel bir toplantıda sunulmamıştır. Çalısmamızı destekleyen kurum veya ... more Araştırmamız daha önce bilimsel bir toplantıda sunulmamıştır. Çalısmamızı destekleyen kurum veya kuruluş yoktur.
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