Eiko Hanaoka

Osaka Prefecture University, Graduate School of Humanities and Sustainable System Sciences, Emeritus

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She was born in1938 inTokyo (Dr.theol. at Hamburg University and Dr.Litt.at Kyoto university.)She is now Prof. emerita of Osaka Prefecture University.She was completed Postgraduate course of Kyoto university and Hamburg University in Germany. She is now an Honorary member of Japanese Association for Religious Studies.She was received Internatinal Order of Merit and life long patron (from IBS, A.D.2000)as well as World Laureate and International Directory of distinguished Leadership(from ABI, A.D.2000).

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Andrej Dujella

University of Zagreb

Hemin Koyi

Uppsala University

Jana Javornik

University of East London

Graham Martin

University of Leicester

Gwen Robbins Schug

University of North Carolina at Greensboro

Gabriel Gutierrez-Alonso

University of Salamanca

John Sutton

Macquarie University

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Universidade Federal do Rio Grande do Sul

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Swansea University

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University of Copenhagen

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Papers by Eiko Hanaoka

The Absolute Openness as the Groundless Ground of All Nature

The Selected Works of Nishitani Keiji

Buddhist–Christian Studies, 1991

Caos y cosmos en el zen

有機体の哲学における時と永遠の問題 : M・ハイデッガーの実存哲学との比較において

人文学論集, Mar 20, 1999

禅における"始原"と"一即一切

人文学論集, Mar 1, 1995

西田哲学における「絶対無の場所」の論理をめぐって

人文学論集, Mar 20, 2000

「対話」の問題 : 精神と心の相違を介して(第二部会)(<特集>第六十二回学術大会紀要)

Journal of Religious Studies, 2004

哲学における実在と過程の問題 : 西田哲学とA.N.ホワイトヘッドの哲学を介して

人文学論集, Jan 10, 1998

新しい宗教哲学の問題 : 西田・田辺・西谷の宗教哲学を介して

人文学論集, Mar 20, 2001

H. Asami: Dialogue between Nishida Kitaro and Christianity

Theological Studies in Japan, 2001

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Integrin-Linked Kinase Regulates Interphase and Mitotic Microtubule Dynamics

PLoS ONE, 2013

Integrin-linked kinase (ILK) localizes to both focal adhesions and centrosomes in distinct multip... more Integrin-linked kinase (ILK) localizes to both focal adhesions and centrosomes in distinct multiprotein complexes. Its dual function as a kinase and scaffolding protein has been well characterized at focal adhesions, where it regulates integrinmediated cell adhesion, spreading, migration and signaling. At the centrosomes, ILK regulates mitotic spindle organization and centrosome clustering. Our previous study showed various spindle defects after ILK knockdown or inhibition that suggested alteration in microtubule dynamics. Since ILK expression is frequently elevated in many cancer types, we investigated the effects of ILK overexpression on microtubule dynamics. We show here that overexpressing ILK in HeLa cells was associated with a shorter duration of mitosis and decreased sensitivity to paclitaxel, a chemotherapeutic agent that suppresses microtubule dynamics. Measurement of interphase microtubule dynamics revealed that ILK overexpression favored microtubule depolymerization, suggesting that microtubule destabilization could be the mechanism behind the decreased sensitivity to paclitaxel, which is known to stabilize microtubules. Conversely, the use of a small molecule inhibitor selective against ILK, QLT-0267, resulted in suppressed microtubule dynamics, demonstrating a new mechanism of action for this compound. We further show that treatment of HeLa cells with QLT-0267 resulted in higher inter-centromere tension in aligned chromosomes during mitosis, slower microtubule regrowth after cold depolymerization and the presence of a more stable population of spindle microtubules. These results demonstrate that ILK regulates microtubule dynamics in both interphase and mitotic cells.

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Chaos and Cosmos in Zen

Diogenes, 1994

Shu, the ruler of the Southern Sea, and Hu, the ruler of the Northern Sea, met in the realm of Hu... more Shu, the ruler of the Southern Sea, and Hu, the ruler of the Northern Sea, met in the realm of Hun-tun, the emperor of the Center, that is to say in the world of true reality that contradicted their own as being one of vast disorder. Hun-tun received the two emperors warmly, and they both overcame their knowledge-based and conceptional consciousness, entirely forgot the evaluating, one-sided viewpoint of differentiation. Thus they enjoyed the world of true reality, the land of Hun-tun, Emperor Chaos. Subsequently the two guests wondered how they could possibly repay the kindness of Hun-tun. Concluding their consultation, they decided to present Hun-tun with seven openings the sense doors of the eyes, ears, mouth, and nose. They duly proceeded to bore one opening into Hun-tun every day. However, on the seventh day, when he was finally becoming like a human being, Hun-tun died.’