From Krista:

I was longing for a deep dive on the radiant and common-sense hope that Jason Reynolds embodies after I interviewed him at a Georgetown event last year. I got my chance at the 2025 Aspen Ideas Festival. Jason’s perspective is so urgent for the world we’ve now walked into: on giving ourselves grace to be hopeless, the virtue of stamina, and the hope that stays strong in him from his life in relationship with the very young in our midst — “the arbiters and purveyors of the future” — as well as an occasional stranger in a bar. Jason himself is preternaturally wise as well as talented and kind and humble. He’s become a friend across the years and is one of my favorite people in the world.

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From Krista:

The word “trauma” is used so widely at present, arguably too widely. But it bespeaks a tenor of our shared reality. This episode is a journey inside what I’ve come to see as a parallel universe unfolding, where our species is unlocking knowledge about ourselves and capacities for radical healing of the most extreme trauma and distress. These findings are even giving rise to dramatic healing alliances across political and social lines that are inflamed in the culture at large. 

At universities and research laboratories around the U.S. and the world, there are countless clinical studies, yielding results it’s hard not at times to call miraculous — for complex PTSD, long-term addiction, treatment-resistant depression. What I’m talking about are therapeutically-administered treatments with plant medicines and chemical compounds we call psychedelic or empathogenic.

Use those words, and many of us — including me until not that long ago — might become wary. Like all forces of great power, these can cut in every direction — the dark and the light of the human condition. But the conversation you are about to hear, with one of the leading neuroscientists in this field, revolves around serious, important research in settings designed for careful, beneficial human effect. Gül Dölen’s groundbreaking contribution to all of us is in her fascinating insight into what psychedelically-assisted therapies are revealing about the workings of the human brain and the brain’s capacity to change and the human capacity for major transformation altogether. The potential consequences of this science are intimate and civilizational at once. I see them as a stunning ray of hope in a struggling world.

I interviewed Gül Dölen at the 2025 Aspen Ideas Festival.

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The great primatologist and humanitarian, Jane Goodall, died on October 1, 2025, at the age of 91. It is a joy and a comfort to revisit our last broadcast of her 2020 conversation with Krista. Jane Goodall began her epic work studying chimpanzees in the Gombe forest without even a college degree. The science she proceeded to do recalled modern Western science to the fact that we are a part of nature, not separate from it. She spent the last decades of her life on the road, often with the young, tending to human fear and misunderstanding. In this beautiful conversation from the pandemic lockdown, she shared the moral and spiritual wisdom that emerged in her extraordinary life — and the hope that, to the end, sustained her.

We are strange creatures. It is hard for us to speak about, or let in, the reality of frailty and death — the elemental fact of mortality itself. In this century, western medicine has gradually moved away from its understanding of death as a failure — where care stops with a terminal diagnosis. Hospice has moved, from something rare to something expected. And yet advances in technology have made it ever harder for physicians and patients to make a call to stop fighting death — often at the expense of the quality of this last time of life. Meanwhile, there is a new longevity industry which resists the very notion of decline, much less finitude.

Fascinatingly, the simple question which transformed the surgeon Atul Gawande’s life and practice of medicine is this: What does a good day look like? As he has come to see, standing reverently before our mortality is an exercise in more intricately inhabiting why we want to be alive. This conversation evokes both grief and hope, sadness at so many deaths — including our species-level losses to Covid — that have not allowed for this measure of care. Yet it also includes very actionable encouragement towards the agency that is there to claim in our mortal odysseys ahead.

In this all-new episode, Krista engages biomimicry pioneer Janine Benyus in a second, urgent conversation, alongside creative biomimicry practitioner Azita Ardakani Walton. Together they trace precise guidance and applied wisdom from the natural world for the civilizational callings before us now.

What does nature have to teach us about healing from trauma? And how might those of us aspiring to good and generative lives start to function like an ecosystem rather than a collection of separate, siloed projects? We are in kinship. How to make that real — and in making it real, make it more of an offering to the whole wide world?

Krista, Azita, and Janine spoke at the January 2024 gathering of visionaries, activists, and creatives where Krista also drew out Lyndsey Stonebridge and Lucas Johnson for the recent episode on Hannah Arendt. We’re excited to bring you back into that room.

The years of pandemic and lockdown are still working powerfully on us from the inside. But we have trouble acknowledging this, much less metabolizing it. This conversation with Christine Runyan, which took place in the dark middle of those years, helps make sense of our present of still-unfolding epidemic distress — as individuals, as communities, as a species. She has cultivated a reverence for the human nervous system. She tells truths about our bodies that western medicine itself is only fitfully learning to see. This quiet conversation is not just revelatory, but healing and calming. It holds startling prescience about some of what we’re navigating now. And it offers self-compassion and simple strategies for finding ease within ourselves — and with each other — as we live forward from here.

There is a quiet, redemptive story of our time in this conversation — a radical way of approaching the gravest of our problems by attending to how original vitality functions. Biomimicry takes the natural world as mentor and teacher — for, as Janine Benyus puts it, “we are surrounded by geniuses.” Nature solves problems and performs what appear to us as miracles in every second, all around: running on sunlight, fitting form to function, recycling everything, relentlessly “creating conditions conducive to life.” Janine launched this way of seeing and imagining as a field with her 1997 book, Biomimicry: Innovation Inspired by Nature. Today she teaches and consults with all kinds of projects and organizations, including major corporations, as you’ll hear.

Welcome to this unfolding parallel universe in our midst, which might just shift the way you see almost everything about our possible futures.

This conversation was part of The Great Northern Festival, a celebration of Minnesota’s signature cold, creative winters.

One of the most fascinating developments of our time is that human qualities we have understood in terms of virtue — experiences we’ve called spiritual — are now being taken seriously by science as intelligence — as elements of human wholeness. Dacher Keltner and his Greater Good Science Center at Berkeley have been pivotal in this emergence. From the earliest years of his career, he investigated how emotions are coded in the muscles of our faces, and how they serve as “moral sensory systems.” He was called on as Emojis evolved; he consulted on Pete Docter’s groundbreaking movie Inside Out.

All of this, as Dacher sees it now, led him deeper and deeper into investigating the primary experience of awe in human life — moments when we have a sense of wonder, an experience of mystery, that transcends our understanding. These, it turns out, are as common in human life globally as they are measurably health-giving and immunity-boosting. They bring us together with others, again and again. They bring our nervous system and heartbeat and breath into sync — and even into sync with other bodies around us.

Amidst all of the perspectives and arguments around our ecological future, this much is true: we are not in the natural world — we are part of it. The next-generation marine biologist Ayana Elizabeth Johnson would let that reality of belonging show us the way forward. She loves the ocean. She loves human beings. And she’s animated by questions emerging from those loves — and from the science she does — which we scarcely know how to take seriously amidst so much demoralizing bad ecological news. This hour, Krista draws out her creative and pragmatic inquiry: Could we let ourselves be led by what we already know how to do, and by what we have it in us to save? What, she asks, if we get this right?

The British psychologist Kimberley Wilson works in the emergent field of whole body mental health, one of the most astonishing frontiers we are on as a species. Discoveries about the gut microbiome, for example, and the gut-brain axis; the fascinating vagus nerve and the power of the neurotransmitters we hear about in piecemeal ways in discussions around mental health. The phrase “mental health” itself makes less and less sense in light of the wild interactivity we can now see between what we’ve falsely compartmentalized as physical, emotional, mental, even spiritual. And so much of what we’re seeing brings us back to intelligence that has always been in the very words we use — “gut instinct,” for instance. It brings us back to something your grandmother was right about, for reasons she would never have imagined: you are what you eat. There is so much actionable knowledge in the tour of the ecosystem of our bodies that Kimberley Wilson takes us on this hour. This is science that invites us to nourish the brains we need, young and old, to live in this world.

Few books have been more eagerly passed from hand to hand with delight in these last years than Robin Wall Kimmerer’s Braiding Sweetgrass. Krista interviewed her in 2015, and it quickly became a much-loved show as her voice was just rising in common life. Robin is a botanist and also a member of the Citizen Potawatomi Nation. She’s written, “Science polishes the gift of seeing, Indigenous traditions work with gifts of listening and language.” An expert in moss — a bryologist — she describes mosses as the “coral reefs of the forest.” Robin Wall Kimmerer opens a sense of wonder and humility for the intelligence in all kinds of life we are used to naming and imagining as inanimate.

The ornithologist J. Drew Lanham is lyrical in the languages of science, humans, and birds. His celebrated books include The Home Place: Memoirs of a Colored Man’s Love Affair with Nature and a collection of poetry and meditations called Sparrow Envy: Field Guide to Birds and Lesser Beasts. J. Drew Lanham’s way of seeing and hearing and noticing the present and the history that birds traverse — through our backyards and beyond — is a revelatory way to be present to the world and to life in our time.

This conversation took place in partnership with The Great Northern.

The astrophysicist Mario Livio spent 24 years at the Space Telescope Science Institute working with the Hubble Telescope, which has revealed the reality and beauty of the Universe to scientists and citizens in whole new ways. The Hubble’s successor, the James Webb Telescope, will become fully operational in 2022, and will further some of the questions about the early formation of the Universe and the origins of life to which Mario Livio has been devoted. Krista spoke with him in 2010, and this conversation has become an On Being Classic, imparting a thrilling sense of all we are learning about the cosmos in this generation in time, our terrible earthly woes notwithstanding. Also: how scientific advance always meets recurrent mystery, from the emergence of life in the Universe to the very heart of mathematics and the puzzle of dark matter and dark energy.

Trabian Shorters is a visionary who has seen and named a task that is necessary for all healing and building, for every vision and plan, whether in a family or a world, to flourish. It’s called Asset Framing — and it works with both new understandings of the brain and an age-old understanding of the real-world power of the words we use, the stories we tell, and the way we name things and people. From everyday social media, to hallowed modes of journalistic, academic, and policy analyses, we have a habit of seeing deficits — and of defining people in need in terms of their problems. This has not only doomed some of our best efforts to failure — it leaves all of us prone to cynicism and hopelessness. What’s exciting is that what Trabian Shorters proposes is not only more effective, it is simple and straightforward to grasp. It is in and of itself dignifying and renewing. The main question you might be asking at the end of this is why, at this advanced stage of our species, it took us so long to learn to asset frame.

The esteemed writer Jane Hirshfield has been a Zen monk and a visiting artist among neuroscientists. She has said this: “It’s my nature to question, to look at the opposite side. I believe that the best writing also does this … It tells us that where there is sorrow, there will be joy; where there is joy, there will be sorrow … The acknowledgement of the fully complex scope of being is why good art thrills … Acknowledging the fullness of things,” she insists, “is our human task.” And that’s the ground Krista meanders with Jane Hirshfield in this conversation: the fullness of things — through the interplay of Zen and science, poetry and ecology — in her life and writing.

What if the future of well-being is about “tipping the scales in the world away from fear and toward love”? And what if it’s a surgeon general of the United States, Dr. Vivek Murthy, who talks this way? Krista draws him out with his friend, the groundbreaking neuroscientist Richard Davidson. Together they carry deep intelligence and vision from the realms of science and public health, expansively understood. They explore all we are learning to help move us forward as a species. This conversation was held as a live Zoom event, sponsored by the Center for Healthy Minds.

When Krista interviewed the psychiatrist and trauma specialist Bessel van der Kolk for the first time, his book The Body Keeps the Score was about to be published. She described him then as “an innovator in treating the effects of overwhelming experiences on people and society.” She catches up with him in 2021 — as we are living through one vast overwhelming experience after the other. And The Body Keeps the Score is now one of the most widely read books in the pandemic world. His perspective is utterly unique and very practically helpful — on what’s been happening in our bodies and our brains, and how that relationship can become severed and restored.

If we didn’t have vast civilizational challenges upon us, we might be living in a constant state of wonder at what science in this century is learning and showing us about the cosmos and about ourselves — the new questions it’s giving us to live. We are the generation of our species to map the genome, to detect black holes colliding, to hear gravitational waves. The physicist Brian Greene is one of our greatest interpreters from the human enterprise that is science. And in his most recent thinking and writing, there’s a stunning evolution in his own approach to science and life and the matters of purpose and meaning. We delve into his exuberant, cosmic lens on living in the here and the now.