International Journal of Electrical and Computer Engineering (IJECE), 2022
In this paper, the field analysis of the sleeve rotor induction motor (IM) is carried out taking ... more In this paper, the field analysis of the sleeve rotor induction motor (IM) is carried out taking the rotor ends into consideration. Here, the field system equations are derived using the cylindrical model with applying Maxwell's field equations. It is expected that, both starting and maximum torques will increase with taking the rotor ends than that without rotor ends. A simple model is used to establish the geometry of the rotor ends current density and to investigate the air gap flux density. The magnetic flux is assumed to remain radially constant through the very small air gap length between the sleeve and stator surfaces. Variation of the field in the radial direction is ignored and the skin effect in the axial direction is considered. The axial distributions of the air gap flux density, the sleeve current density components and the force density have been determined. The motor performance is carried out taking into account the effects of the rotor ends on the starting and ...
International Journal of Power Electronics and Drive Systems (IJPEDS), 2021
This paper presents an analytical comparison between two-level inverter and three-level neutral p... more This paper presents an analytical comparison between two-level inverter and three-level neutral point diode clamped inverters for electric vehicle traction purposes. The main objective of the research is to declare the main differences in the performance of the two inverter schemes in terms of the switching and conduction losses over an entire domain of the modulation index and the phase angle distribution, steady-state operation, transient operation at a wide range of speed variation, and the total harmonic distortion THD% of the line voltage output waveform. It also declares the analysis of the three-level neutral point diode clamped inverter (NPCI) obstacle and the unbalance of the DC-link capacitor voltages. The introduced scheme presents an Induction Motor (IM) drive for electric vehicle (EV) applications. Considering the dynamic operation of the EV, the speed of the three-phase induction motor is controlled using a scalar V/Hz control for the full range of the IM power factor ...
Transforaminal lumbar interbody fusion (TLIF) is an alternative interbody fusion procedure in whi... more Transforaminal lumbar interbody fusion (TLIF) is an alternative interbody fusion procedure in which interbody space is accessed via a path that runs through the far lateral portion of the vertebral foramen. TLIF reduces the potential complications of other approaches, including the transabdominal approach or posterior lumbar interbody fusion (PLIF), but still achieves clinical outcomes and circumferential fusion results comparable with PLIF. Operative indications for TLIF are contested among many spine experts. The optimal indications for using this technique are spondylolisthesis, degenerative disc disease with a specific discogenic pain pattern, lumbar stenosis with instability and recurrent lumbar disc herniation with radiculopathy. Various instrumentation techniques and graft materials are available to use in TLIF, and each option has benefits and disadvantages. Further research is needed, however, TLIF with one cage and excised local bone and augmented with a bilateral pedicle ...
Sleep is a highly conserved feature of animal life characterized by dramatic changes in behavior,... more Sleep is a highly conserved feature of animal life characterized by dramatic changes in behavior, neural physiology and gene expression. The gene regulatory factors responsible for these sleep-dependent changes remain largely unknown. microRNAs are post-transcriptional modulators of gene expression which have been implicated in sleep regulation. Our previous screen identified 25 sleep-regulating microRNAs in Drosophila melanogaster, including the developmental regulator bantam (ban). Here we show that ban promotes early nighttime sleep through a population of glutamatergic neurons- the γ5β′2a/β′2mp/β′2mp_bilateral Mushroom Body Output Neurons (MBONs). We found that knockdown of ban in these neurons led to a reduction in early night sleep. The γ5β′2a/β′2mp/β′2mp_bilateral MBONs were previously shown to be wake-promoting, suggesting that ban acts to inhibit these neurons. GCaMP calcium imaging revealed that bantam inhibits the neural activity of the γ5β′2a/β′2mp/β′2mp_bilateral MBONs ...
Sweet potato leaves (SPL) have been used by malay rural folks as traditional topical medication f... more Sweet potato leaves (SPL) have been used by malay rural folks as traditional topical medication for eczematous skin conditions especially psoriasis. Local Chinese consume green SPL as vegetable. SPL contains high amount of polyphenols, a proven antioxidant and free radical scavengers. Local green SPL was extracted for hydrophilic and lipophilic compounds using water, ethanol and hexane as solvents. Water extraction method gave the best yield per kg fresh weight. Total phenolic content was 4.48 mg GAE/g dw SPL, slightly lower of Japan’s and USA’s averages. HPLC analysis revealed significant amount of caffeic acid as one of its major phenolic components beside the dominant chlorogenic acid.
Learning to associate a positive or negative experience with an unrelated cue after the presentat... more Learning to associate a positive or negative experience with an unrelated cue after the presentation of a reward or a punishment defines associative learning. The ability to form associative memories has been reported in animal species as complex as humans and as simple as insects and sea slugs. Associative memory has even been reported in tardigrades [1], species that diverged from other animal phyla 500 million years ago. Understanding the mechanisms of memory formation is a fundamental goal of neuroscience research. In this article, we work on resolving the current contradictions between different Drosophila associative memory circuit models and propose an updated version of the circuit model that predicts known memory behaviors that current models do not. Finally, we propose a model for how dopamine may function as a reward prediction error signal in Drosophila, a dopamine function that is well-established in mammals but not in insects [2, 3].
Objectives To examine the relationship between mandibular volume and craniofacial morphology in p... more Objectives To examine the relationship between mandibular volume and craniofacial morphology in patients with cleft lip and palate using cone beam computed tomography (CBCT) and to compare these findings with control (noncleft) patients undergoing CBCT for other purposes during the deciduous dentition period. Materials and Methods Eighty-four patients were categorized into the unilateral cleft lip and alveolus (UCLA) group (n = 25; mean age, 4.60 ± 0.40 years), unilateral cleft lip and palate (UCLP) group (n = 23; mean age, 4.52 ± 0.39 years), bilateral cleft lip and palate (BCLP) group (n = 22; mean age, 4.54 ± 0.37 years), and control group without cleft (n = 14; mean age, 5.19 ± 0.52 years). Mandibular volume and craniofacial cephalometric measurements were obtained using CBCT. All measurements were assessed by analysis of covariance (ANCOVA) using Bonferroni post hoc pairwise comparison tests. Results ANCOVA revealed no statistically significant differences in mandibular volume ...
Introduction. Postoperative acute kidney injury is associated with a higher mortality, a more com... more Introduction. Postoperative acute kidney injury is associated with a higher mortality, a more complicated hospital course with longer hospital stay. Urinary kidney injury molecule 1 may play an important role as an early predictor of acute kidney injury post-cardiopulmonary in open heart surgery. Methods. We evaluated 45 patients who underwent open heart surgery from January 2016 to June 2016. Both urinary kidney injury molecule 1 and serum creatinine were evaluated before operation and 3hs and 24hs after operation. Acute kidney injury was diagnosed according to Kidney Disease: Improving Global Outcomes, 2012 guidelines. Results. In this study, 27 patients developed acute kidney injury. The three hour-post-surgery urinary kidney injury molecule 1 was significantly higher in the acute kidney injury group (P<0.015) and, at the same time, we did not find any significant difference in the serum creatinine levels between the two groups. Conclusion. Although serum creatinine is still t...
To examine the relationship between tooth length and growth hormone receptor (GHR) gene variants ... more To examine the relationship between tooth length and growth hormone receptor (GHR) gene variants in a healthy Japanese population. The subjects consisted of 193 Japanese adults (69 men, 124 women), aged 13 to 56 years. Genomic DNA was extracted from saliva and genotyped GHR rs6184 and rs6180 variants using the Taqman genotyping. Computed tomography (CT) images were acquired using a dental cone-beam CT scanner and reconstructed using open-source OsiriX medical image processing software. The maxillary (upper; U) and mandibular (lower, L) central incisors (1), lateral incisors (2), canines (3), first premolars (4), second premolars (5), first molars (6), and second premolars (7) were evaluated. Teeth were assessed for crown height (CH), root length (RL), overall tooth length (C+R), and crown to root ratio (C/R). The relationships between GHR variants and CH, RL, C+R, and C/R were statistically examined. The GHR variant rs6184 was associated with the root lengths and tooth length for th...
The Showa University Journal of Medical Sciences, 2017
A signi cant genetic component is involved in the development of the craniofacial form. Recently,... more A signi cant genetic component is involved in the development of the craniofacial form. Recently, the growth hormone receptor gene GHR variants rs6180 and rs6184 were associated with variations in mandibular form. To con rm these ndings we evaluated the relationship between these GHR variants and mandibular form in a cohort of Egyptian individuals with a normal skull form. The patients consisted of 191 unrelated Egyptian adults 92 males, 99 females ; 18-55 years. Allele frequencies of the rs6180 and rs6184 variants were determined from genomic DNA extracted from saliva using the Taqman genotyping assay. Lateral and posteroanterior cephalometric tracings were used to obtain 19 mandibular measurements. The association between the GHR variants and the mandibular measurements was examined using regression analysis. The frequency of the minor rs6184 variant was very low at 1.5 : therefore, association studies were not performed for this variant. The rs6180 variant was not associated with any of the measurements representing mandibular form in our study cohort. The frequency of the rs6184 variant was very low in our cohort of Egyptian subjects. We also found no association between the rs6180 variant and the measurements representing the mandibular form. By excluding the involvement of these GHR variants in in uencing mandibular form, our results may help to identify the actual variant s affecting the mandibular form in the Egyptian population.
A common disorder of human dentition is the existence of supernumerary teeth. Impacted supernumer... more A common disorder of human dentition is the existence of supernumerary teeth. Impacted supernumerary teeth occur most frequently in the maxillary incisor area and are termed mesiodens. We conducted whole-exome sequencing of non-syndromic Japanese individuals possessing supernumerary teeth to identify genes and/or loci involved in the pathogenesis of the condition.
similar, and there was a tendency toward dental protrusion in the Egyptian groups [11]. Hassan ev... more similar, and there was a tendency toward dental protrusion in the Egyptian groups [11]. Hassan evaluated the cephalometric features of a Saudi population living in the western area of Saudi Arabia and revealed distinct cephalometric features in the Saudis [12]. In their studies on Anatolian Turkish adults who are considered part of the Mediterranean population, Basciftci et al. established cephalometric norms for Turkish men and women and studied the sex differences in this population. They found that the Anatolian Turkish have a long lower anterior facial height with retroclined upper incisors and proclined lower incisors [13]. The Moroccan population, which is a North African population, was examined by Ousehal et al. who established cephalometric norms based on Steiner's analysis, and their results indicated a more retruded mandible and maxilla with large skeletal sagittal discrepancies [14]. Aboul-Azm et al. established craniofacial and soft tissue standards for the Egyptian population. Twenty-two angular measurements, 13 linear measurements, and three ratios were established for the most significant skeletal, dental, and soft-tissue parameters [15]. The aim of the present study was to identify the cephalometric norms in an adult Egyptian population and compare the values of Egyptian males
To investigate the relationship between anteroposterior and vertical differences in maxillofaci... more To investigate the relationship between anteroposterior and vertical differences in maxillofacial morphology and mandibular volume. Subjects comprised 213 Japanese adults (84 males and 129 females) who were divided into three groups based on mandibular basal arch (ANB) and Wits, measured in a cephalometric analysis: Class I (-1° ≤ ANB < 4°,-1 mm ≤ Wits < 0 mm), Class II (ANB ≥ 4°, Wits ≥ 0), and Class III (ANB <-1°, Wits <-1 mm). Subjects were also divided into three groups based on the mandibular plane angle (Mp), as follows: hypodivergent (Mp < 23°), normodivergent (Mp = 23-30°), and hyperdivergent (Mp > 30°) groups. Mandibular volume was measured from cone-beam computed tomographic images that were analyzed using Analyze™ image processing software and compared among the three groups in each classification. No significant differences were noted in mandibular volume among Classes I, II, and III. An inverse relationship was found between mandibular volume a...
Conducting high throughput -omics research requires high quality, data-rich biospecimens to unrav... more Conducting high throughput -omics research requires high quality, data-rich biospecimens to unravel factors underlying childhood cancers; this is an extra burden in a limited resources country. For this purpose, Children's Cancer Hospital (CCHE), the largest pediatric cancer hospital worldwide, established a cutting-edge Biorepository and Biospecimen Research Facility (CCHE-BBR). To present a step-by-step guide to establishing a hospital-based biorepository with limited resources, and working in collaboration with different hospital facilities to supply the research community with high quality data-rich biospecimens fit for a wide range of research purposes. This approach will foster research in the era of personalized precision medicine. CCHE-IRB approved the collection and storage of biospecimens from patients and parents for future research. We focused on staff training, recruiting qualified scientists, and establishing the infrastructure. The CCHE Biorepository developed str...
Objective Postmastectomy pain is responsible for distress with subsequent organ dysfunction. Syst... more Objective Postmastectomy pain is responsible for distress with subsequent organ dysfunction. Systemic analgesics such as opioids are not free of complications. The idea of preincisional mastectomy flap infiltration with bupivacaine and adrenaline was shown by many reports to decrease the postmastectomy pain and analgesic requirements. The aim of this study was to prove this with the assessment of the stress-response changes. Patients and methods A total of 120 females who were candidates for mastectomy were randomized into an equal two groups using computer-generated random numbers; first was the study group in which the mastectomy flap was infiltrated before skin incision with bupivacaine and adrenaline, whereas the second was a control. Assessment of patient and operative data was done. Results There was no statistical difference between both groups regarding the demographic data, the tumor pathological data, hospital stay, and overall complications. The mean operative time was significantly longer in the study group ( P = 0.01). The mean blood loss was significantly less in the study group ( P = 0.001). The mean postoperative arterial blood pressure and pulse were significantly less in the study group ( P = 0.004 and 0.04, respectively). The mean intraoperative fentanyl and mean postoperative nalbuphine requirements were significantly less in the study group ( P = 0.007 and 0.002, respectively). Visual analogue scale was significantly less in the study group ( P = 0.01). Conclusion Pre-emptive mastectomy flap infiltration with bupivacaine adrenaline solution is a safe and effective method for reduction of postmastectomy pain and stress response with a significant reduction of the analgesic requirements.
We describe a testing framework that can provide online estimates of audio and video call quality... more We describe a testing framework that can provide online estimates of audio and video call quality on network paths, without requiring either end-user involvement or prior availability of audio/video sequences or network traces. The framework includes a tool that emulates the audio and video traffic of IP calls and employs an extended E-Model to measure the audio quality and VQM to estimate video quality. Additionally, it can emulate network impairments to run experiments in different network conditions. Our experiment results show that the quality measurements acquired using the framework compare well to the most commonly applied industry standard for objective voice and video offline testing—PESQ and PSNR respectively.
Maintaining good Quality-of-Experience (QoE) is crucial for Voice-over-IP (VoIP) applications, pa... more Maintaining good Quality-of-Experience (QoE) is crucial for Voice-over-IP (VoIP) applications, particularly those operating across the public Internet. Accurate online estimation of QoE as perceived by end users allows VoIP applications take steps to improve QoE when it falls below acceptable levels. ITU-T recommendation G.107 introduced the E-model, which provides a means to assess QoE levels for two-party VoIP sessions. In this paper we provide an analysis of the accuracy of the E-model for multi-party VoIP sessions when all audio is processed by a centralised focus node. We analyse the impact of what we term the "Focus Transcoding Effect (FTE)," the "Focus Forwarding Effect (FFE)," and the number of end-points participating in the session. Through comparison to QoE metrics produced by the offline PESQ method for three common audio codecs, we show that the standard E-model does not provide accurate QoE assessment for multi-party VoIP sessions. We then introduce an improved Emodel for these codecs for multi-party VoIP sessions. We describe the implementation of the improved E-model in a QoE monitoring application, showing that it produces results similar to actual PESQ scores.
International Journal of Electrical and Computer Engineering (IJECE), 2022
In this paper, the field analysis of the sleeve rotor induction motor (IM) is carried out taking ... more In this paper, the field analysis of the sleeve rotor induction motor (IM) is carried out taking the rotor ends into consideration. Here, the field system equations are derived using the cylindrical model with applying Maxwell's field equations. It is expected that, both starting and maximum torques will increase with taking the rotor ends than that without rotor ends. A simple model is used to establish the geometry of the rotor ends current density and to investigate the air gap flux density. The magnetic flux is assumed to remain radially constant through the very small air gap length between the sleeve and stator surfaces. Variation of the field in the radial direction is ignored and the skin effect in the axial direction is considered. The axial distributions of the air gap flux density, the sleeve current density components and the force density have been determined. The motor performance is carried out taking into account the effects of the rotor ends on the starting and ...
International Journal of Power Electronics and Drive Systems (IJPEDS), 2021
This paper presents an analytical comparison between two-level inverter and three-level neutral p... more This paper presents an analytical comparison between two-level inverter and three-level neutral point diode clamped inverters for electric vehicle traction purposes. The main objective of the research is to declare the main differences in the performance of the two inverter schemes in terms of the switching and conduction losses over an entire domain of the modulation index and the phase angle distribution, steady-state operation, transient operation at a wide range of speed variation, and the total harmonic distortion THD% of the line voltage output waveform. It also declares the analysis of the three-level neutral point diode clamped inverter (NPCI) obstacle and the unbalance of the DC-link capacitor voltages. The introduced scheme presents an Induction Motor (IM) drive for electric vehicle (EV) applications. Considering the dynamic operation of the EV, the speed of the three-phase induction motor is controlled using a scalar V/Hz control for the full range of the IM power factor ...
Transforaminal lumbar interbody fusion (TLIF) is an alternative interbody fusion procedure in whi... more Transforaminal lumbar interbody fusion (TLIF) is an alternative interbody fusion procedure in which interbody space is accessed via a path that runs through the far lateral portion of the vertebral foramen. TLIF reduces the potential complications of other approaches, including the transabdominal approach or posterior lumbar interbody fusion (PLIF), but still achieves clinical outcomes and circumferential fusion results comparable with PLIF. Operative indications for TLIF are contested among many spine experts. The optimal indications for using this technique are spondylolisthesis, degenerative disc disease with a specific discogenic pain pattern, lumbar stenosis with instability and recurrent lumbar disc herniation with radiculopathy. Various instrumentation techniques and graft materials are available to use in TLIF, and each option has benefits and disadvantages. Further research is needed, however, TLIF with one cage and excised local bone and augmented with a bilateral pedicle ...
Sleep is a highly conserved feature of animal life characterized by dramatic changes in behavior,... more Sleep is a highly conserved feature of animal life characterized by dramatic changes in behavior, neural physiology and gene expression. The gene regulatory factors responsible for these sleep-dependent changes remain largely unknown. microRNAs are post-transcriptional modulators of gene expression which have been implicated in sleep regulation. Our previous screen identified 25 sleep-regulating microRNAs in Drosophila melanogaster, including the developmental regulator bantam (ban). Here we show that ban promotes early nighttime sleep through a population of glutamatergic neurons- the γ5β′2a/β′2mp/β′2mp_bilateral Mushroom Body Output Neurons (MBONs). We found that knockdown of ban in these neurons led to a reduction in early night sleep. The γ5β′2a/β′2mp/β′2mp_bilateral MBONs were previously shown to be wake-promoting, suggesting that ban acts to inhibit these neurons. GCaMP calcium imaging revealed that bantam inhibits the neural activity of the γ5β′2a/β′2mp/β′2mp_bilateral MBONs ...
Sweet potato leaves (SPL) have been used by malay rural folks as traditional topical medication f... more Sweet potato leaves (SPL) have been used by malay rural folks as traditional topical medication for eczematous skin conditions especially psoriasis. Local Chinese consume green SPL as vegetable. SPL contains high amount of polyphenols, a proven antioxidant and free radical scavengers. Local green SPL was extracted for hydrophilic and lipophilic compounds using water, ethanol and hexane as solvents. Water extraction method gave the best yield per kg fresh weight. Total phenolic content was 4.48 mg GAE/g dw SPL, slightly lower of Japan’s and USA’s averages. HPLC analysis revealed significant amount of caffeic acid as one of its major phenolic components beside the dominant chlorogenic acid.
Learning to associate a positive or negative experience with an unrelated cue after the presentat... more Learning to associate a positive or negative experience with an unrelated cue after the presentation of a reward or a punishment defines associative learning. The ability to form associative memories has been reported in animal species as complex as humans and as simple as insects and sea slugs. Associative memory has even been reported in tardigrades [1], species that diverged from other animal phyla 500 million years ago. Understanding the mechanisms of memory formation is a fundamental goal of neuroscience research. In this article, we work on resolving the current contradictions between different Drosophila associative memory circuit models and propose an updated version of the circuit model that predicts known memory behaviors that current models do not. Finally, we propose a model for how dopamine may function as a reward prediction error signal in Drosophila, a dopamine function that is well-established in mammals but not in insects [2, 3].
Objectives To examine the relationship between mandibular volume and craniofacial morphology in p... more Objectives To examine the relationship between mandibular volume and craniofacial morphology in patients with cleft lip and palate using cone beam computed tomography (CBCT) and to compare these findings with control (noncleft) patients undergoing CBCT for other purposes during the deciduous dentition period. Materials and Methods Eighty-four patients were categorized into the unilateral cleft lip and alveolus (UCLA) group (n = 25; mean age, 4.60 ± 0.40 years), unilateral cleft lip and palate (UCLP) group (n = 23; mean age, 4.52 ± 0.39 years), bilateral cleft lip and palate (BCLP) group (n = 22; mean age, 4.54 ± 0.37 years), and control group without cleft (n = 14; mean age, 5.19 ± 0.52 years). Mandibular volume and craniofacial cephalometric measurements were obtained using CBCT. All measurements were assessed by analysis of covariance (ANCOVA) using Bonferroni post hoc pairwise comparison tests. Results ANCOVA revealed no statistically significant differences in mandibular volume ...
Introduction. Postoperative acute kidney injury is associated with a higher mortality, a more com... more Introduction. Postoperative acute kidney injury is associated with a higher mortality, a more complicated hospital course with longer hospital stay. Urinary kidney injury molecule 1 may play an important role as an early predictor of acute kidney injury post-cardiopulmonary in open heart surgery. Methods. We evaluated 45 patients who underwent open heart surgery from January 2016 to June 2016. Both urinary kidney injury molecule 1 and serum creatinine were evaluated before operation and 3hs and 24hs after operation. Acute kidney injury was diagnosed according to Kidney Disease: Improving Global Outcomes, 2012 guidelines. Results. In this study, 27 patients developed acute kidney injury. The three hour-post-surgery urinary kidney injury molecule 1 was significantly higher in the acute kidney injury group (P<0.015) and, at the same time, we did not find any significant difference in the serum creatinine levels between the two groups. Conclusion. Although serum creatinine is still t...
To examine the relationship between tooth length and growth hormone receptor (GHR) gene variants ... more To examine the relationship between tooth length and growth hormone receptor (GHR) gene variants in a healthy Japanese population. The subjects consisted of 193 Japanese adults (69 men, 124 women), aged 13 to 56 years. Genomic DNA was extracted from saliva and genotyped GHR rs6184 and rs6180 variants using the Taqman genotyping. Computed tomography (CT) images were acquired using a dental cone-beam CT scanner and reconstructed using open-source OsiriX medical image processing software. The maxillary (upper; U) and mandibular (lower, L) central incisors (1), lateral incisors (2), canines (3), first premolars (4), second premolars (5), first molars (6), and second premolars (7) were evaluated. Teeth were assessed for crown height (CH), root length (RL), overall tooth length (C+R), and crown to root ratio (C/R). The relationships between GHR variants and CH, RL, C+R, and C/R were statistically examined. The GHR variant rs6184 was associated with the root lengths and tooth length for th...
The Showa University Journal of Medical Sciences, 2017
A signi cant genetic component is involved in the development of the craniofacial form. Recently,... more A signi cant genetic component is involved in the development of the craniofacial form. Recently, the growth hormone receptor gene GHR variants rs6180 and rs6184 were associated with variations in mandibular form. To con rm these ndings we evaluated the relationship between these GHR variants and mandibular form in a cohort of Egyptian individuals with a normal skull form. The patients consisted of 191 unrelated Egyptian adults 92 males, 99 females ; 18-55 years. Allele frequencies of the rs6180 and rs6184 variants were determined from genomic DNA extracted from saliva using the Taqman genotyping assay. Lateral and posteroanterior cephalometric tracings were used to obtain 19 mandibular measurements. The association between the GHR variants and the mandibular measurements was examined using regression analysis. The frequency of the minor rs6184 variant was very low at 1.5 : therefore, association studies were not performed for this variant. The rs6180 variant was not associated with any of the measurements representing mandibular form in our study cohort. The frequency of the rs6184 variant was very low in our cohort of Egyptian subjects. We also found no association between the rs6180 variant and the measurements representing the mandibular form. By excluding the involvement of these GHR variants in in uencing mandibular form, our results may help to identify the actual variant s affecting the mandibular form in the Egyptian population.
A common disorder of human dentition is the existence of supernumerary teeth. Impacted supernumer... more A common disorder of human dentition is the existence of supernumerary teeth. Impacted supernumerary teeth occur most frequently in the maxillary incisor area and are termed mesiodens. We conducted whole-exome sequencing of non-syndromic Japanese individuals possessing supernumerary teeth to identify genes and/or loci involved in the pathogenesis of the condition.
similar, and there was a tendency toward dental protrusion in the Egyptian groups [11]. Hassan ev... more similar, and there was a tendency toward dental protrusion in the Egyptian groups [11]. Hassan evaluated the cephalometric features of a Saudi population living in the western area of Saudi Arabia and revealed distinct cephalometric features in the Saudis [12]. In their studies on Anatolian Turkish adults who are considered part of the Mediterranean population, Basciftci et al. established cephalometric norms for Turkish men and women and studied the sex differences in this population. They found that the Anatolian Turkish have a long lower anterior facial height with retroclined upper incisors and proclined lower incisors [13]. The Moroccan population, which is a North African population, was examined by Ousehal et al. who established cephalometric norms based on Steiner's analysis, and their results indicated a more retruded mandible and maxilla with large skeletal sagittal discrepancies [14]. Aboul-Azm et al. established craniofacial and soft tissue standards for the Egyptian population. Twenty-two angular measurements, 13 linear measurements, and three ratios were established for the most significant skeletal, dental, and soft-tissue parameters [15]. The aim of the present study was to identify the cephalometric norms in an adult Egyptian population and compare the values of Egyptian males
To investigate the relationship between anteroposterior and vertical differences in maxillofaci... more To investigate the relationship between anteroposterior and vertical differences in maxillofacial morphology and mandibular volume. Subjects comprised 213 Japanese adults (84 males and 129 females) who were divided into three groups based on mandibular basal arch (ANB) and Wits, measured in a cephalometric analysis: Class I (-1° ≤ ANB < 4°,-1 mm ≤ Wits < 0 mm), Class II (ANB ≥ 4°, Wits ≥ 0), and Class III (ANB <-1°, Wits <-1 mm). Subjects were also divided into three groups based on the mandibular plane angle (Mp), as follows: hypodivergent (Mp < 23°), normodivergent (Mp = 23-30°), and hyperdivergent (Mp > 30°) groups. Mandibular volume was measured from cone-beam computed tomographic images that were analyzed using Analyze™ image processing software and compared among the three groups in each classification. No significant differences were noted in mandibular volume among Classes I, II, and III. An inverse relationship was found between mandibular volume a...
Conducting high throughput -omics research requires high quality, data-rich biospecimens to unrav... more Conducting high throughput -omics research requires high quality, data-rich biospecimens to unravel factors underlying childhood cancers; this is an extra burden in a limited resources country. For this purpose, Children's Cancer Hospital (CCHE), the largest pediatric cancer hospital worldwide, established a cutting-edge Biorepository and Biospecimen Research Facility (CCHE-BBR). To present a step-by-step guide to establishing a hospital-based biorepository with limited resources, and working in collaboration with different hospital facilities to supply the research community with high quality data-rich biospecimens fit for a wide range of research purposes. This approach will foster research in the era of personalized precision medicine. CCHE-IRB approved the collection and storage of biospecimens from patients and parents for future research. We focused on staff training, recruiting qualified scientists, and establishing the infrastructure. The CCHE Biorepository developed str...
Objective Postmastectomy pain is responsible for distress with subsequent organ dysfunction. Syst... more Objective Postmastectomy pain is responsible for distress with subsequent organ dysfunction. Systemic analgesics such as opioids are not free of complications. The idea of preincisional mastectomy flap infiltration with bupivacaine and adrenaline was shown by many reports to decrease the postmastectomy pain and analgesic requirements. The aim of this study was to prove this with the assessment of the stress-response changes. Patients and methods A total of 120 females who were candidates for mastectomy were randomized into an equal two groups using computer-generated random numbers; first was the study group in which the mastectomy flap was infiltrated before skin incision with bupivacaine and adrenaline, whereas the second was a control. Assessment of patient and operative data was done. Results There was no statistical difference between both groups regarding the demographic data, the tumor pathological data, hospital stay, and overall complications. The mean operative time was significantly longer in the study group ( P = 0.01). The mean blood loss was significantly less in the study group ( P = 0.001). The mean postoperative arterial blood pressure and pulse were significantly less in the study group ( P = 0.004 and 0.04, respectively). The mean intraoperative fentanyl and mean postoperative nalbuphine requirements were significantly less in the study group ( P = 0.007 and 0.002, respectively). Visual analogue scale was significantly less in the study group ( P = 0.01). Conclusion Pre-emptive mastectomy flap infiltration with bupivacaine adrenaline solution is a safe and effective method for reduction of postmastectomy pain and stress response with a significant reduction of the analgesic requirements.
We describe a testing framework that can provide online estimates of audio and video call quality... more We describe a testing framework that can provide online estimates of audio and video call quality on network paths, without requiring either end-user involvement or prior availability of audio/video sequences or network traces. The framework includes a tool that emulates the audio and video traffic of IP calls and employs an extended E-Model to measure the audio quality and VQM to estimate video quality. Additionally, it can emulate network impairments to run experiments in different network conditions. Our experiment results show that the quality measurements acquired using the framework compare well to the most commonly applied industry standard for objective voice and video offline testing—PESQ and PSNR respectively.
Maintaining good Quality-of-Experience (QoE) is crucial for Voice-over-IP (VoIP) applications, pa... more Maintaining good Quality-of-Experience (QoE) is crucial for Voice-over-IP (VoIP) applications, particularly those operating across the public Internet. Accurate online estimation of QoE as perceived by end users allows VoIP applications take steps to improve QoE when it falls below acceptable levels. ITU-T recommendation G.107 introduced the E-model, which provides a means to assess QoE levels for two-party VoIP sessions. In this paper we provide an analysis of the accuracy of the E-model for multi-party VoIP sessions when all audio is processed by a centralised focus node. We analyse the impact of what we term the "Focus Transcoding Effect (FTE)," the "Focus Forwarding Effect (FFE)," and the number of end-points participating in the session. Through comparison to QoE metrics produced by the offline PESQ method for three common audio codecs, we show that the standard E-model does not provide accurate QoE assessment for multi-party VoIP sessions. We then introduce an improved Emodel for these codecs for multi-party VoIP sessions. We describe the implementation of the improved E-model in a QoE monitoring application, showing that it produces results similar to actual PESQ scores.
Uploads
Papers by Mohamed Adel