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An investigational drug that inhibits serotonin synthesis in the gut, administered orally once daily, effectively cured osteoporosis in mice and rats reports an international team led by researchers from Columbia University Medical Center, in the Feb. 7 issue of Nature Medicine. Serotonin in the gut has been shown in recent research to stall bone formation. The finding could lead to new therapies that build new bone; most current drugs for osteoporosis can only prevent the breakdown of old bone.

“New therapies that inhibit the production of serotonin in the gut have the potential to become a novel class of drugs to be added to the therapeutic arsenal against osteoporosis,” said Gerard Karsenty, M.D., Ph.D., chair of the Department of Genetics and Development at Columbia University College of Physicians and Surgeons, lead author of the paper. “With tens of millions of people worldwide affected by this devastating and debilitating bone loss, there is an urgent need for new treatments that not only stop bone loss, but also build new bone. Using these findings, we are working hard to develop this type of treatment for human patients.”

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Cross-posted from http://moosl.dreamwidth.org/93201.html (with comment count unavailable comments there).

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  • moosl
    18 Nov 2010, 18:57
    Well I am sure Georgeanne knows the local crowd far better than I do, and what they might be likely to purchase.
  • moosl
    18 Nov 2010, 14:36
    Kiwi's sister, at whose home we're having the show, was strongly in favor of clock hands sweeping over body parts. She thinks it would sell well to the St Louis art crowd. I was initially putting the…
  • moosl
    18 Nov 2010, 14:05
    some of them are lovely photos, but the clock doesn't fit in well (e.g. kwan yin - there's no place for the clock to go). the chihuly tentacle is great in that respect, because there is a natural hub…
  • moosl
    18 Nov 2010, 12:48
    Geoff might well like to have this!! Some amazing pix came out of that day :) And I like the implied comparison of a clock=time with soap bubble=ephemerality... (is that a word??)

    It's pretty hard…
  • moosl
    16 Nov 2010, 20:01
    priceless :)
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