Papers by Parsa Yousefichaijan
Background &Objectives: Antiemetic drugs can be used in complicated cases of vomiting secondary t... more Background &Objectives: Antiemetic drugs can be used in complicated cases of vomiting secondary to gastroenteritis. There is no previous study dealing with the use of pyridoxine in treatment of vomiting in pediatrics. This Studyintendsto review the effects of intravenous pyridoxine on control of gastroenteritis related vomiting. Methods: This study is a single blind randomized clinical trial with placebo. A total number of 147 children diagnosed with gastroenteritis induced vomiting and admitted in Amirkabir hospital from August to December 2011 were studied and divided to two case andcontrol groups. In the control group intravenous fluid with distilled water (placebo) was used and the pyridoxine was given along with intravenous fluid therapy in case group. Since admission for three days, numbers of vomiting and other symptoms were collected in data form. Results were analyzed using SPSS-16 by means of descriptive analysis for basic information. Results: Most children were male, aged between 6 months and 2 years and having urban life. There was no significant difference between two groups in the mean of vomiting frequency during the period of hospitalization (p>0.05).There was also no significant difference between two groups in duration of hospitalization (p=0.19). Conclusion: Based on this study pyridoxine (Vitamin B6) was not effective in treatment of vomiting due to gastroenteritis in children, and did not reduce the duration of hospitalization.
Diabetic nephropathy: a strong predictor of sleep quality in hemodialysis patients
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2014
Sleep complaints are common in hemodialysis (HD) patients. Sleep quality (SQ) is a predictor of q... more Sleep complaints are common in hemodialysis (HD) patients. Sleep quality (SQ) is a predictor of quality of life and mortality risk in HD. The aim of this study was to examine factors that may have a role in SQ. In this cross-sectional analytic study, 138 end-stage renal disease patients receiving maintenance HD for >3 months were included. The Pittsburgh Sleep Quality Index (PSQI) was used to measure individual's SQ. Patients with a global PSQI score >5 were assumed as poor sleepers. Eighty-eight patients (64%) were classified as poor sleepers. Poor sleepers were older and more likely had diabetes. They had significantly higher serum ferritin and calcium levels and lower serum parathyroid hormone level (all P-values <0.05). The global PSQI score was positively correlated with age, serum calcium level and presence of diabetes as the underlying cause of renal failure. In the multi-variable binary regression model, presence of diabetes (Odds Ratio (OR) = 3.67, P = 0.008) a...
Zinc Supplementation in Treatment of Children With Urinary Tract Infection
Iranian journal of kidney diseases, 2016
Urinary tract infection (UTI) is very common in children. Precocious diagnosis and appropriate tr... more Urinary tract infection (UTI) is very common in children. Precocious diagnosis and appropriate treatment are important because of the permanent disease complications. Zinc increases the response to treatment in many infections. In this study, we explored the effect of zinc in treating UTI. Two hundred children with UTI were divided into 2 groups of 100 who were comparable in terms of age, sex, urine laboratory profiles, and clinical signs and symptoms. The control group received a standard treatment protocol for UTI and the intervention group received oral zinc sulfate syrup plus routine treatment of UTI. A faster recovery was observed in the patients receiving zinc, but abdominal pain was exacerbated by zinc and lasted longer. Three months after the treatment, there was no significant difference between the two groups in the time of fever stop and negative urine culture. In children with UTI, zinc supplementation has a positive effect in ameliorating severe dysuria and urinary freq...
Arak Medical University Journal, Feb 15, 2013
Background: Adequately delivered hemodialysis dose has been shown to have a distinct impact upon ... more Background: Adequately delivered hemodialysis dose has been shown to have a distinct impact upon the morbidity and mortality of patients on chronic dialysis therapy. Online conductivity monitoring (OCM) using sodium flux as a surrogate for urea allows for repeated measurement of hemodialysis adequacy in each treatment session.
Emotional Disorders in Pediatric Renal Transplant Recipients: A Comparative Study
Journal of Pediatric Nephrology, 2015
Journal of Pediatric Nephrology, Jun 17, 2014
Vesicoureteral reflux refers to the retrograde flow of the urine from the bladder to the ureter a... more Vesicoureteral reflux refers to the retrograde flow of the urine from the bladder to the ureter and kidney. The ureteral attachment to the bladder is normally oblique, between the bladder mucosa and detrusor muscle, creating a flap-value mechanism that prevents reflux. Reflux occurs when the submucosal tunnel between the mucosa and detrusor muscle is short or absent. The inflammatory reaction caused by pyelonephritis can result in scarring, which is also termed reflux nephropathy. Since sacral bone anomalies have a direct influence on the final function of the urinary and bowel systems, this study was performed to investigate the relationship between sacral ratio and reflux nephropathy.
Journal of renal injury prevention, 2015
Vesicoureteral reflux (VUR) is a backward flow of urine from bladder to ureter or kidney. Potenti... more Vesicoureteral reflux (VUR) is a backward flow of urine from bladder to ureter or kidney. Potential reflux is harmful because of kidney being faced with the hemodynamic high-pressure during urination. This project was carried out for high prevalence of VUR and delay in growth of children with chronic diseases. In case of growth disorder in children with this disease and its difference with healthy person, treatment can be tried by treating the growth disorder. The purpose of this study is survey of children with VUR about growth and developmental impairment. All patients who performed voiding cystourethrogram (VCUG)because of UTI, divided into 2 groups, healthy and sick. History and checklist filled, patients' height and weight measured in a standard way and ASQ questionnaires adjusted to age, used for the studying development effect. The height and weight of children measured by standard meter and scale and used the curves adjusted to age and sex. Control group entered the stud...
The prevalence of hypercalciuria in girl kids with over active bladder
Journal of renal injury prevention, 2015
Hypercalciuria may be a sign of over active bladder, these symptoms may be treated if we get rid ... more Hypercalciuria may be a sign of over active bladder, these symptoms may be treated if we get rid of hypercalciuria. This paper is intended to get to the prevalence of hypercalciuria in girl kids with over active bladder. All patients with index of over active urinary bladder who admitted to Amir-Kabir hospital of Arak and children who have admitted without any particular disease just for a laboratory check were studied simultaneously. Urine sample was taken from both groups. The prevalence of hypercalciuria in the group with normal urinary bladder was 22.6% and in the case group was 42.9%. Hypercalciuria was reported in 30 (22.6%) children of control group and 57 (42.9%) children of case group. Based on chi-square test, hypercalciuria distribution between the two groups is not homogeneous (P = 0.001). Mean calcium to creatinine ratios were 2.384330 ± 0.55694 (mg/mg) and 2.186552 ± 0.56714 (mg/mg) for control and case groups respectively and no significant difference is observed betw...
Is Additional Fluid Therapy Effective in the Treatment of Children with Urinary Tract Infection?
Journal of Pediatric Nephrology, 2016
Journal of Pediatric Nephrology, Sep 16, 2014
Assessment of Blood Pressure in Primary Monosymptomatic Nocturnal Enuresis
Journal of Pediatric Nephrology, 2016
Emotional Disorders in Children with Monosymptomatic Primary Nocturnal Enuresis
Journal of Pediatric Nephrology, 2015
Therapeutic Efficacy of Hydrochlorothiazide in Primary Monosymptomatic Nocturnal Enuresis in Boys With Idiopathic Hypercalciuria
Nephro-Urology Monthly, 2015
Idiopathic hypercalciuria (IHC) can be one of the causes of nocturnal enuresis (NE) and hydrochlo... more Idiopathic hypercalciuria (IHC) can be one of the causes of nocturnal enuresis (NE) and hydrochlorothiazide (HCT) ameliorates hypercalciuria. The aim of this study was to assess the therapeutic efficacy of HCT in boys with primary monosymptomatic NE (PMNE). This study was a randomized double-blind placebo-controlled clinical trial. A hundred boys with PMNE and IHC were randomly assigned into two groups of experimental (treated with HCT 1 mg/kg/day) and control and all patients were followed for 4 months for the number of wet-night episodes. The mean numbers of wet-night episodes in the first (intervention: 8.34 ± 8.54, control: 9.1 ± 9.3, P = 0.3), second (7.1 ± 7.3, 7.9 ± 8.1, P = 0.4), third (7.8 ± 8, 7.9 ± 8.1, P = 0.1) and fourth (4.9 ± 5.1, 5.9 ± 6, P = 0.3) months were not significantly different between the two groups. However, the decrease in the average wet-night episodes during the 4 months of treatment in the intervention group (P = 0.019) unlike the control group. Not more significant compared to control group (P = 0.191). All patients who were treated by HCT became normocalciuric. However, in 21 patients the dose was increased to 2 mg/kg/day. Single daily dose of HCT is a safe and effective therapeutic option in the treatment of PMNE in children with IHC.
Journal of Pediatric Nephrology, Jun 17, 2014
Obsessive Compulsive Inventory-Child Version (OCV-CI) to Evaluate Obsessive Compulsive Disorder in Children With Early Stages of Chronic Kidney Disease: A Case Control Study
Nephro-Urology Monthly, 2016
Chronic kidney disease (CKD) is a common medical condition among children and obsessive-compulsiv... more Chronic kidney disease (CKD) is a common medical condition among children and obsessive-compulsive disorder (OCD) is a frequent, chronic, costly, and disabling disorder among them. The aim of this study was to investigate obsessive-compulsive disorder (OCD) in children with early stages of CKD, and to compare it with the occurrence of OCD in healthy children. In this case-control study, we evaluated 160 children aged 7 to 17 years old who were visited in the pediatric clinics of Amir-Kabir hospital, Arak, Iran. The control group consisted of 80 healthy children and the case group included 80 children with Stage 1 to 3 CKD. The ages and sex of the children in the two groups were matched. OCD in children was evaluated using the obsessive compulsive inventory-child version (OCI-CV). The mean scores of doubting/checking (case: 3.52 ± 2.54, control: 2.5 ± 2.32, P = 0.007) and ordering (case: 2.59 ± 1.81, control: 1.5 ± 2.56, P = 0.005) in the children with CKD was significantly higher than in the healthy ones. Moreover, the mean total scores for the OCI-CV of the children with CKD at 15.32 ± 7.69 was significantly higher than the scores of the healthy ones at 11.12 ± 2.54 (P = 0.021). There was a significant correlation between the CKD duration and doubting/checking (P = 0.004, correlation coefficient (CC): 0.4), obsessing (P = 0.06, CC: 0.02), washing (P = 0.031, CC: 0.8), ordering (P = 0.001, CC: 0.2), and the total scores of the OCI-CV questionnaire (P = 0.04, CC: 0.4). The risk of OCD in children with CKD is significantly higher than that in healthy children. Although the results seem to suggest that psychiatric intervention can be helpful in treating OCD in children with CKD, further investigation into the medical condition is required so as to obtain more definitive conclusions.
Congenital anomalies of kidney and upper urinary tract in children with congenital hypothyroidism; a case-control study
Journal of renal injury prevention, 2015
Congenital hypothyroidism (CH) may be significantly associated with congenital malformations. How... more Congenital hypothyroidism (CH) may be significantly associated with congenital malformations. However, there is little evidence on the relationship between renal and urinary tract anomalies and CH. The aim of this study was to compare the renal and upper urinary tract anomalies in children with and without primary CH (PCH). This case-control study was conducted on 200 children aged 3 months to 1 year, referring to Amir-Kabir hospital, Arak, Iran. One hundred children with PCH, as the case group, and 100 children without CH, as the control group, were selected. For all children, ultrasonography and other diagnostic measures (if necessary) were performed to evaluate renal and upper urinary tract anomalies (ureter and bladder). The frequency of renal and upper urinary tract anomalies among 43 children with primary CH, with 83 cases (72.8%), was significantly higher than the frequency of anomalies among the 19 children in the control group, with 31 cases (27.1%) (OR = 3; CI 95%: 1.6-5.4...
Helicobacter pylori Seropositivity in Children With Asthma
Archives of Pediatric Infectious Diseases, 2016
Attention deficit hyperactivity disorder in children with primary monosymptomatic nocturnal enuresis: A case-control study
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2016
Attention deficit hyperactivity disorder (ADHD) is one of the most common childhood neurological ... more Attention deficit hyperactivity disorder (ADHD) is one of the most common childhood neurological disorders. The aim of this study was to investigate ADHD in children with primary monosymptomatic nocturnal enuresis (PMNE) and compare it with healthy children. A total of 100 five to 16-year-old children with PMNE and 100 healthy children without NE were included in this case-control study as the cases and control groups, respectively. Subjects were selected from children who were referred to the pediatric clinic of the Amir Kabir Hospital of Arak, Iran, based on inclusion and exclusion criteria. ADHD was diagnosed by Conner's Parent Rating Scale-48 and the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria and was confirmed by consultation with a psychiatrist. Data were analyzed by binomial test using SPSS18. ADHD inattentive type was observed in 16 cases (16%) with PMNE and five controls (5%) (P = 0.01). Despite these significant differences in the cas...
Delayed Sleep Phase Disorder in Children With Non-Monosymptomatic Primary Nocturnal Enuresis
International Journal of Clinical Pediatrics, 2015
Prevalence of Obsessive-Compulsive Disorder in Pediatric Patients with the Daytime Frequency Syndrome of Childhood or Pollakiuria
Arak Medical University Journal, Oct 15, 2014
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Papers by Parsa Yousefichaijan