Papers by Mostafa Abolfotouh
International journal of general medicine, Mar 1, 2024

Clinical, Cosmetic and Investigational Dentistry, Sep 30, 2023
Background: Physicians are more likely to examine children than dentists; thus, they may have a s... more Background: Physicians are more likely to examine children than dentists; thus, they may have a significant role in detecting oral and dentofacial problems. This study aimed to determine the rate and comprehensiveness of examinations, the rate and quality of referral practices, and the predictors of referral practice of physicians regarding orthodontic problems among children. Methods: In a multi-center cross-sectional study, a total of 518 physicians in Saudi Arabia were subjected to an e-questionnaire of four sections: (1) Physicians' demographic and work-related characteristics; (2) Physicians' comprehensiveness of oral and orthodontic examinations; (3) Physicians' referral practices to orthodontists and reasons considered for referral; and (4) Physicians' sources of orthodontic education. Logistic regression analysis was applied to identify the significant predictors of referral practice. The significance was set at p < 0.05. Results: Most physicians reported partial oral (78.5%) and orthodontic (72.2%) examinations, while the full examination was reported by only 12% and 2.5% of physicians, respectively. Referral to orthodontists was practiced by most of the physicians (83.8%), yet for the majority of them, the quality of referral was poor (40.3%) or fair (46.1%), with only 13.6% who practiced quality referral. Dental development issues (53.3%) and functional issues (51.5%) were reported as the main reasons for referral, followed by family/patient request (42.9%), dental alignment (42.5%), oral respiratory issues (32.4%), and finally jaw relation (26.1%). Referral practice was predicted by the comprehensive oral (OR = 2.37, p = 0.007) and orthodontic (OR = 4.26, p < 0.001) examinations, number of patients seen by the physician (OR = 1.58, p = 0.007), and level of training (OR = 1.88, p = 0.03). Conclusion: Although most physicians reported high rates of examination and referral practices on orthodontic problems among children in Saudi Arabia, only a small portion showed comprehensive examinations and quality referral practice. Including dental courses in medical curricula and improving oral and orthodontic examination guidelines for physicians are recommended.

Research Square (Research Square), Aug 31, 2020
Background Background. Many studies are available in literature about e-health in Saudi Arabia, h... more Background Background. Many studies are available in literature about e-health in Saudi Arabia, however, data is limited to a few organizations and does not necessarily re ect the the current and potential use of e-health for health care organizations in the country. The aim of this study was to determine the level of awareness of Saudi medical students of the internet-based health-related information seeking and developing to support health services and signi cant predictors of their practice. Methods. A crosssectional survey of 440 medical students in Riyadh, Saudi Arabia, was conducted, during October/November 2019, using a previously validated questionnaire, to assess: (1) knowledge in three domains; e-health de nition (13 statements), elds of application of e-health (8 statements), methods of using e-health (7 statements), (2) attitude toward using e-health (8 statements) and (3) reported practice of e-health in medical training (5 statements). A scoring system was used to calculate the total and percentage score of knowledge, attitude and practice for each student. Multiple regression analysis was applied to identify predictors of e-health practice. Signi cance was considered at p<0.05. Results. Of 440 medical students surveyed, the majority were females (55.7%) and from families whose monthly income was more than 10,000SR (82.8%). Overall knowledge about e-health was unsatisfactory (percentage mean score, PMS=71.6%), with only 43.6% of students reporting satisfactory level. However, this level was satisfactory for elds of application (Percentage mean score-PMS=76.6%) and unsatisfactory for de nition of e-health (PMS=70.7%) and methods of its use (PMS=65.7%) domains. Overall attitude

PubMed, 1990
This study aimed at the assessment of growth and nutritional status of preschool children by comp... more This study aimed at the assessment of growth and nutritional status of preschool children by comparing it with internationally recognized growth standards, using the anthropometric indices of nutritional status. A cross-sectional study was carried out upon a sample of children (N = 660) aged 0-71 months who attended the well-baby clinics in the MCH centres in Alexandria. Individual measurements of weight and height were done for each child. Anthropometric indices of weight and height were calculated. These indices were related to the US National Centre of Health Statistics (NCHS) reference population by standard deviation scores (Z-scores). The growth pattern of children was different from that of western reference populations, while it resembled that of most developing countries. Of all children, 10.5% suffered from malnutrition (weight for age less than 2 S.D. of the reference median), 14.1% were stunted, and 5.5% were wasted. Parents of all children were interviewed, and analysis of specific social risk factors associated with poor attained size was done using stepwise multiple regression analysis. Few of such factors reached statistically significant association such as sex, infant feeding pattern, birth order and parental consanguinity.

Research Square (Research Square), Sep 25, 2020
Background. Healthcare workers (HCWs) face considerable mental and physical stress caring for pat... more Background. Healthcare workers (HCWs) face considerable mental and physical stress caring for patients with Covid-19. They are at higher risk of acquiring and transmitting this virus. This study aims to assess perception and attitude of HCWs in Saudi Arabia with regard to Covid-19, and to identify potential associated predictors. Methods. In a cross-sectional study, HCWs at three tertiary hospitals in Saudi Arabia were surveyed via email with an anonymous link, by a concern scale about Covid-19 pandemic during 15-30 April, 2020. Concerns of disease severity, governmental efforts to contain it and disease outcomes were assessed using 32 concern statements in ve distinct domains. Multiple regression analysis was used to identify predictors of high concern scores. Results. A total of 844 HCW responded to the survey. Their average age was 40.4±9.5 years, 40.3% were nurses, 58.2% had direct patient contact, and 77.3% were living with others. The majority of participants (72.1%) had overall concern scores of 55 or less out of a maximum score of 96 points, with an overall mean score of 48.5±12.8 re ecting moderate level of concern. Three-fourth of respondents felt at risk of contracting Covid-19 infection at work, 69.1% felt threatened if a colleague contracted Covid-19, 69.9% felt obliged to care for patients infected with Covid-19 while 27.7% did not feel safe at work using the standard precautions available. Nearly all HCWs believed that the government should isolate patients with Covid-19 in specialized hospitals (92.9%), agreed with travel restriction to and/or from areas affected by Covid-19 (94.7%) and felt safe the government implemented curfew and movement restriction periods (93.6%). Predictors of high concern scores were; HCWs of Saudi nationality (p<0.001), younger age (p=0.003), undergraduate education (p=0.044), living with others (p=0.003) working in the western region (p=0.003) and direct contact with patients (p=0.018). Conclusions. This study highlights the high concern among HCWs about Covid-19 and identi es the predictors of those with highest concern levels. To minimize the potential negative impact of those concerns on the performance of HCWs during pandemics, measures are necessary to enhance their protection and to minimize the psychological effect of the perceived risk of infection.

Journal of Biochemical and Clinical Genetics, 2023
Background: Preimplantation genetic testing (PGT) is used to identify a pathogenic variant in emb... more Background: Preimplantation genetic testing (PGT) is used to identify a pathogenic variant in embryos created through in vitro fertilization. A "variant of uncertain significance" (VOUS) is a genetic variant discovered through genetic testing but with unknown clinical significance. The primary goal is to gauge geneticists' perspectives on performing PGT-M for VOUS in Saudi Arabia, which results in the development of recommendations from higher authorities regarding the criteria of PGT-M in clinical practice. Methods: After reviewing the literature, a cross-sectional study was conducted employing questionnaire developed using survey monkey. The reliability of the questionnaire was assessed in terms of internal consistency and Cronbach's alpha-assessed test-retest. Results: In particular, a total of 96 Saudis and non-Saudis, male and female geneticists, agreed to participate in the study. Out of the 96 geneticists, 56 (59.6%) were female. Most participants were of Saudi origin, with a percentage of (76.6%). The most important finding of this study is that 64% of geneticists opposed performing PGT-M for VOUS. The outcome that 94.5% of geneticists concurred that PGT-M is poorly understood was another noteworthy finding. Conclusion: Future research with a larger sample size is required for performing PGT-M for VOUS, which will help in developing guidelines for PGT-M in Saudi Arabia.

PubMed, 1993
The aim of this study is to illustrate a method for adjusting the internationally used National C... more The aim of this study is to illustrate a method for adjusting the internationally used National Center for Health Statistics (NCHS) growth curves for local use in the assessment of nutritional status of Saudi children. All children 1-60 months in three semiurban-rural communities in Asir region, Saudi Arabia (N = 1168) were subjected to weight and height (or length) measurements. These measurements were individually compared with those of the NCHS reference population. The distribution of the study population was found to be significantly shifted to the left of the normal distribution for reference population on the percentile growth curves (P < 0.001). This denoted the inappropriateness of the NCHS reference standards for local use. Accordingly, the lower limits for the expected normal on the growth curves has been shifted from the 3rd percentile line to -3 standard deviation line, to be suitable for the Saudi children. This led to 70% & 56% reductions in the estimation of undernutrition, based on wt/age and ht/age indicators respectively. It is recommended that this adjustment be supported by other studies locally and in other developing countries.
North American Spine Society Journal (nassj), Jun 1, 2023

Global Spine Journal, Dec 23, 2022
Study Design Cross-sectional survey. Objectives This study aimed to investigate work-related neck... more Study Design Cross-sectional survey. Objectives This study aimed to investigate work-related neck pain among AO spine surgeons in different regions by estimating its prevalence, predictors, consequences, and management methods. Methods A cross-sectional survey of 411 spine surgeon members of AO spine was conducted during March–May 2021, using the Modified Nordic Questionnaire and the Neck Disability Index. Data on neck pain experience during the last 12 months and its consequences and risk factors were collected. Logistic regression analysis was done to identify significant predictors of neck pain. Significance was set at P &lt; .05. Results The 1-year neck pain was experienced by 66.7% of surgeons. According to the Neck Disability Index, more than one-half (52.8%) experienced disability due to neck pain of mild (45.5%), moderate (6.5%), and severe (.8%) grades. Neck pain was responsible for stopping work in 17.5% of surgeons, with a median of 3.5 (IQR, 2-7.8) days off work. One-half of the participants (56.3%) were treated by medical care, 31.5% by physiotherapy, and 16.5% requested rest days and sick leave. Physical stress (P &lt; .001) and non-exercising (P = .04) were the significant predictors of neck pain. Conclusion The 12-month prevalence of neck pain was high among spine surgeons, with an impact on activities of daily living, mainly of a mild degree, reported by one-half of surgeons. Physical stress was the only significant predictor, while sports practice was a protective factor against neck pain. Medication was the primary management adopted—an increased focus on pain prevention through improved workplace ergonomics and sports activity programs is recommended.

International Journal of Women's Health, Jul 1, 2023
Background: Pelvic organ prolapse (POP) is a medical condition that profoundly impacts women's qu... more Background: Pelvic organ prolapse (POP) is a medical condition that profoundly impacts women's quality of life. Unfortunately, the literature lacks long-term predictors and risk factors for its recurrence. This study aims to assess the efficacy and safety of Sacrocolpopexy/Sacrohysteropexy and to identify the predictors of recurrence in a Saudi setting. Methods: In a retrospective cohort study, all patients who underwent Sacrocolpopexy (n=144) and Sacrohysteropexy (n=56) between 2009-2021 were followed up. Electronic medical records were examined to collect data on the following: Patient characteristics [age, parity, BMI, and past medical and surgical history], prolapse-related characteristics/symptoms, Surgery-related characteristics [type and approach of surgery, mesh type, and concomitant surgery], and Outcome characteristics. Postoperative anatomical success and failure rates were determined according to the Baden-Walker classification. Logistic regression analysis was applied to identify the predictors of overall anatomical failure of Sacrocolpopexy. Significance was considered at p<0.05. Results: Success rates of 96.8%, 99.4%, and 85.2% were detected in the anterior, apical, and posterior vaginal prolapse, respectively, with an overall success rate of 83.1%. The overall failure rate was 15.9%, with an incidence density of 5.98 per 100 women-years. The onset of failure in 27 failure cases ranged from 40 days to 11.5 years postoperative. After adjustment for the possible potential confounders, older age (OR=1.06, 95% CI:1.01-1.13, p=0.03) and the presence of diabetes (OR=4.93, 95% CI:1.33-18.33, p=0.02) were the only significant predictors of operation failure. As for complications, six cases (3.6%) required reoperation, two cases (1.2%) had a bowel obstruction two and seven years after surgery, and one patient (0.6%) had vaginal mesh exposure. Conclusion: The outcomes of Sacrocolpopexy/Sacrohysteropexy in our study are comparable to those in previous studies. Diabetes and elder age at the time of the surgery played a role in predicting recurrence. Sacrocolpopexy has a long-term profile of safety and efficacy. These findings could be key to stratifying surgical plans for pelvic organ prolapse cases.
Eastern Mediterranean Health Journal, Sep 2, 2021
Eastern Mediterranean Health Journal, Sep 2, 2021
Journal of Infection and Public Health, Jul 1, 2015
Journal of Infection and Public Health, Jul 1, 2015

Journal of Clinical Oncology, May 20, 2013
e17528 Background: Enrollment of patients in CR may be impacted by their levels of awareness and ... more e17528 Background: Enrollment of patients in CR may be impacted by their levels of awareness and attitude toward participation. Our study aims at assessing the awareness and willingness to participate in CR and identifying the barriers and influencing factors for participation. Methods: A cross-sectional study was performed using an interview-based questionnaire composed of close-ended questions conducted by trained research coordinators. Descriptive statistics, univariate and multivariate analyses were applied. Results: A total of 300 patients were enrolled in the study with a median age of 53.6 (42.2 - 64.0), and 188 patients (62.67%) were females. The majority of patients 289 (97.31%) were not aware of what is institutional review board. On the other hand, 226 (75.33%) showed interest in CR participation, if offered. The trust in treating physician (88.33 %) and the belief that participation in CR offers a better chance of cure (73.14%) were the two most important influencing factors to participate, while the preference of receiving standard treatment (43.13%) and the unknown efficacy of treatment (40.32%) were the top two barriers to participate. In univarate analyses, patients younger than 45 years (p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.015) and those with higher education (more than middle school) (p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.022) were significantly more interested in CR participation. However; in a multivariate analysis, higher education was the only significant predictor of interest to participate (p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.023). Conclusions: There is an apparent gap in cancer patients’ awareness about CR. However, there is an obvious interest in participation in CR especially in patients with higher education level. Enhancing public awareness is crucial to improve CR participation.

Journal of Clinical Oncology, May 20, 2013
e17528 Background: Enrollment of patients in CR may be impacted by their levels of awareness and ... more e17528 Background: Enrollment of patients in CR may be impacted by their levels of awareness and attitude toward participation. Our study aims at assessing the awareness and willingness to participate in CR and identifying the barriers and influencing factors for participation. Methods: A cross-sectional study was performed using an interview-based questionnaire composed of close-ended questions conducted by trained research coordinators. Descriptive statistics, univariate and multivariate analyses were applied. Results: A total of 300 patients were enrolled in the study with a median age of 53.6 (42.2 - 64.0), and 188 patients (62.67%) were females. The majority of patients 289 (97.31%) were not aware of what is institutional review board. On the other hand, 226 (75.33%) showed interest in CR participation, if offered. The trust in treating physician (88.33 %) and the belief that participation in CR offers a better chance of cure (73.14%) were the two most important influencing factors to participate, while the preference of receiving standard treatment (43.13%) and the unknown efficacy of treatment (40.32%) were the top two barriers to participate. In univarate analyses, patients younger than 45 years (p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.015) and those with higher education (more than middle school) (p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.022) were significantly more interested in CR participation. However; in a multivariate analysis, higher education was the only significant predictor of interest to participate (p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.023). Conclusions: There is an apparent gap in cancer patients’ awareness about CR. However, there is an obvious interest in participation in CR especially in patients with higher education level. Enhancing public awareness is crucial to improve CR participation.
Saudi journal of obesity, 2017
Annals of Saudi Medicine, May 1, 1996

PubMed, 1995
High prevalence of diarrhea was reported among people living in a semiurban community in Shebaa a... more High prevalence of diarrhea was reported among people living in a semiurban community in Shebaa area in Southwestern Saudi Arabia. This was in comparison to prevalence in a nearby urban community in Abha, the capital city of The Southwestern Region of Saudi Arabia. Contamination of the desalinated water, commonly used for drinking, was one possible hypothesis for occurrence of this diarrhea problem. The objective of the present study was to test bacteriological potability of desalinated water in both Shebaa and Abha areas and to determine whether any contamination occurred during transportation from water distribution stations to houses or during storage in house reservoirs. Water samples were collected and analyzed by the Presumptive Coliform Test from a sample of water tankers transporting water and from tap water originating from house reservoirs in a sample of houses in the two areas. Source of drinking water was recorded for each of such houses. Of 117 water samples from 39 tankers transporting water, only one sample was positive bacteriologically and non-potable (potability = 99%). Whereas among 201 tap water samples from a random sample of houses, 26.4% showed contamination. Bacteriological non-potability was found in a significantly higher proportion of houses in Shebaa area (38.4%) than in Abha city (7.9%), (p<0.001). Also, desalinated water was used for drinking significantly more in Shebaa than in Abha (p<0.001). It is concluded that transportation of the desalinated water by water tankers has not significantly contributed to its contamination. Such contamination rather obviously occurred during storage in house reservoirs, and was possibly implicated, at least partly, in the increased prevalence of diarrhea in Shebaa.
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Papers by Mostafa Abolfotouh