Papers by J.E. Ashenbrener
Long known for their role in structural support, neuronal migration, and lamination (Romero and B... more Long known for their role in structural support, neuronal migration, and lamination (Romero and Borrell, 2015), radial-glial cells have, over the past few decades, been shown to be responsible for all neurogenesis and folding in vertebrates in the ventricular zone as well as cell creation throughout the nervous system in a variety of developing organisms. Anthony, C. Klein, and G. Fishell (2004) demonstrate that in fact most neurons derive from radial glia, and Y. Yokota and colleagues (2010) describe in depth the asymmetric cell division that gives rise to cells involved in neural development and the inter-glial interactions and polarity that drive this dynamic process. Despite consensus regarding their centrality to neurogenesis in the developing brain, regional differences throughout the brain and CNS may moderate the potential of the glial cells in generating new cells (2004). So what does this cell creation process look like, and what players are involved?
A student paper drawing from leading publications on the topic.
Episodic memory allows for the recollection of experiences and the spatial-temporal relations bet... more Episodic memory allows for the recollection of experiences and the spatial-temporal relations between them (Tulving, 1985). While it is widely accepted that humans have episodic memory, there is less agreement over whether animals have episodic memory. To circumvent the difficulty of testing a species without language for memory, this study focused on exploring episodic-like memory. Clayton and Dickinson (1998) defined episodic-like memory as the ability to remember the what, where, and when components of an event. The current experiment aimed to determine whether mice have episodic-like memory by requiring Deer mice in a radial arm maze to run to different arms sequentially before obtaining reinforcement. Although the mice recalled that food was delivered (what) in one of the arms (where), they failed to learn the correct sequence of arms (when). Thus, our experiment did not support the hypothesis that Deer mice have episodic memory. In 1985, Endel Tulving developed a model for a hierarchical memory system that comprised
Cf. the Morris Water Maze experiments and concomitant publications in 1981 and 1982. Richard Morris uncovered evidence of spatial memory in mice in pools. The author of the present study wonders if activation of the amygdala in these vertebrate land animals may have influenced their ability to recall key information such as the location of a dry platform under duress. See M. Cyders et. al (2015) "Negative Urgency Mediates the Relationship between Amygdala and Orbitofrontal Cortex Activation to Negative Emotional Stimuli and General Risk-Taking."
Drafts by J.E. Ashenbrener
RGC as Progenitor Cells, 2023
Long known for their role in structural support and neuronal migration (Romero and Borrell, 2015)... more Long known for their role in structural support and neuronal migration (Romero and Borrell, 2015), radial-glial cells have, over the past few decades, been shown to be responsible for all neurogenesis and folding in vertebrates in the ventricular zone as well as cell creation throughout the nervous system in a variety of developing organisms. Anthony, C. Klein, and G. Fishell (2004) demonstrate that in fact most neurons derive from radial glia, and Y. Yokota and colleagues (2010) describe in depth the asymmetric cell division that gives rise to cells involved in neural development and the inter-glial interactions and polarity that drive this dynamic process. Despite consensus regarding their centrality to neurogenesis in the developing brain, regional differences throughout the brain and CNS may moderate the potential of the glial cells in generating new cells (2004). So what does this cell creation process look like, and what players are involved?
An Overview of Neurogenesis in the Brain and CNS
...
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Papers by J.E. Ashenbrener
Cf. the Morris Water Maze experiments and concomitant publications in 1981 and 1982. Richard Morris uncovered evidence of spatial memory in mice in pools. The author of the present study wonders if activation of the amygdala in these vertebrate land animals may have influenced their ability to recall key information such as the location of a dry platform under duress. See M. Cyders et. al (2015) "Negative Urgency Mediates the Relationship between Amygdala and Orbitofrontal Cortex Activation to Negative Emotional Stimuli and General Risk-Taking."
Drafts by J.E. Ashenbrener
An Overview of Neurogenesis in the Brain and CNS
...
Cf. the Morris Water Maze experiments and concomitant publications in 1981 and 1982. Richard Morris uncovered evidence of spatial memory in mice in pools. The author of the present study wonders if activation of the amygdala in these vertebrate land animals may have influenced their ability to recall key information such as the location of a dry platform under duress. See M. Cyders et. al (2015) "Negative Urgency Mediates the Relationship between Amygdala and Orbitofrontal Cortex Activation to Negative Emotional Stimuli and General Risk-Taking."
An Overview of Neurogenesis in the Brain and CNS
...