Jama-journal of The American Medical Association, 1995
The article byDr Levyand colleaguesin this issueofThe Jour-nal1 addresses the important issue of ... more The article byDr Levyand colleaguesin this issueofThe Jour-nal1 addresses the important issue of driver's license renewal for elderlyindividuals. Whether the reduction in crash mortality found by Levy et al is related to visual testing specifically or to a requirement for retesting in ...
The present study utilized an in vivo antisense strategy to examine the functional interaction of... more The present study utilized an in vivo antisense strategy to examine the functional interaction of supraspinal /x-opioid receptors with the G protein subunits Gila, Gi2a, Gi3a and Gsa. Mice were injected intracerebroventricularly (i.c.v.) with 33-base phosphorothioate oligodeoxyribonucleotides (12.5 /zg) or with vehicle in equal volume (sterile water, 5 /~1) and the antinociceptive responses to i.c.v, morphine, [D-Ala2,NMePhe4,GlyS-ol]enkephalin (DAMGO) or sufentanil were determined 18-24 h later using the tail-flick test. Treatment with antisense to Gi2a, but not the other subunits, significantly attenuated morphine-induced antinociception. The degree of attenuation for the three ~-opioid agonists was in the order morphine > DAMGO > sufentanil, the inverse of their intrinsic efficacy.
Atmospheric Environment. Part A. General Topics, 1992
... UV ABSORPTION SPECTRA OF SEVERAL ALIPHATIC ALDEHYDES AND KETONES AT 300 K RICHARD D. MARTINEZ... more ... UV ABSORPTION SPECTRA OF SEVERAL ALIPHATIC ALDEHYDES AND KETONES AT 300 K RICHARD D. MARTINEZ, ALVARO A. BUITRAGO, NOEL W. HOWELL ... annual and diurnal OH concentration in the tropo-sphere of 0.3-3.0x 106 molecule cm-3 (Hewitt and Harrison ...
Jama-journal of The American Medical Association, 1995
The article byDr Levyand colleaguesin this issueofThe Jour-nal1 addresses the important issue of ... more The article byDr Levyand colleaguesin this issueofThe Jour-nal1 addresses the important issue of driver's license renewal for elderlyindividuals. Whether the reduction in crash mortality found by Levy et al is related to visual testing specifically or to a requirement for retesting in ...
The present study utilized an in vivo antisense strategy to examine the functional interaction of... more The present study utilized an in vivo antisense strategy to examine the functional interaction of supraspinal /x-opioid receptors with the G protein subunits Gila, Gi2a, Gi3a and Gsa. Mice were injected intracerebroventricularly (i.c.v.) with 33-base phosphorothioate oligodeoxyribonucleotides (12.5 /zg) or with vehicle in equal volume (sterile water, 5 /~1) and the antinociceptive responses to i.c.v, morphine, [D-Ala2,NMePhe4,GlyS-ol]enkephalin (DAMGO) or sufentanil were determined 18-24 h later using the tail-flick test. Treatment with antisense to Gi2a, but not the other subunits, significantly attenuated morphine-induced antinociception. The degree of attenuation for the three ~-opioid agonists was in the order morphine > DAMGO > sufentanil, the inverse of their intrinsic efficacy.
Atmospheric Environment. Part A. General Topics, 1992
... UV ABSORPTION SPECTRA OF SEVERAL ALIPHATIC ALDEHYDES AND KETONES AT 300 K RICHARD D. MARTINEZ... more ... UV ABSORPTION SPECTRA OF SEVERAL ALIPHATIC ALDEHYDES AND KETONES AT 300 K RICHARD D. MARTINEZ, ALVARO A. BUITRAGO, NOEL W. HOWELL ... annual and diurnal OH concentration in the tropo-sphere of 0.3-3.0x 106 molecule cm-3 (Hewitt and Harrison ...
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