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SAFIA KHAN

Jinnah University For Women, Education, Undergraduate

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name: safia khan
age:19
father name : nauroz khan
address: A 2917 gulshan e hadeed karachi
Supervisors: advisor

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JSS College of Pharmacy, JSS University, Myosre

JSS College of Pharmacy, JSS University, Myosre

Pranita Kashyap

Frederique Suriya

Madan Chaturvedi

University of Delhi

Amrinder kaur Kaur

Universitas Kadiri

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Papers by SAFIA KHAN

Pharmacological importance of Nardostachys jatamansi DC: A potential therapeutic agent in different pathological ailments

Nardostachys jatamansi (Nj.Cr) DC. is an endangered, primitive and therapeutic agent in the famil... more Nardostachys jatamansi (Nj.Cr) DC. is an endangered, primitive and therapeutic agent in the family Valerianaceae. The herbs and rhizomes of this hairy, perennial, dwarf and herbaceous plant are used for medicinal purpose. Mostly herbs and rhizome are used for this hairy, perennial, dwarf and herbaceous plant. Nardostachys jatamansi has been reported to have many therapeutic activities like antifungal, antimicrobial, antioxidant, Hepatoprotective and cardioprotective properties. It is also useful in the management of insomnia and CNS disorders. The vasodilator, bronchodilator, spasmolytic and platelet aggregation inhibition activities of the plant have also been reported. In phytochemical analysis jatamansone, Nardostachone and actinidine have been reported to be present in the plant. This review article is summary of the potential benefits of this medicinal plant as reported in literature. The review also highlights the need for the use of this plant in Ayurveda system of medicine a...

Bio-fabrication of CuO nanoparticles using Leucophyllum frutescens leaf extract and investigation of their photocatalytic cationic dye degradation

Journal of Molecular Structure

What is the purpose of using email? Advantages of using email Reducing stress Cultural differences

How can Internet applications such as " email " be used by school teachers and students... more

Household Balance Sheets in South Africa

Funding for this research from the Department of Planning, Monitoring and Evaluation is gratefull... more

Genetic Improvement of Pulse Crops

Lanthanum-Zinc Binary Oxide Nanocomposite with Promising Heterogeneous Catalysis Performance for the Active Conversion of 4-Nitrophenol into 4-Aminophenol

Coatings

This work intended to enhance the unique and outstanding properties of lanthanum by synthesizing ... more This work intended to enhance the unique and outstanding properties of lanthanum by synthesizing its nanocomposite. A lanthanum-based nanocomposite was prepared by a simple and cost-effective “co-precipitation” method. Lanthanum nitrate (La (NO3)3) and zinc nitrate (Zn (NO3)2) were used as precursors. The lanthanum/zinc oxide nano composite formed was then calcined at 450 °C for 4 h in order to obtain a fine powder with size in the nano range of 1–100 nm. Characterization of the prepared catalyst was done by ultraviolet/visible spectroscopy, Fourier transform infrared spectroscopy, and photoluminescence. Crystallinity and morphology were found by X-ray diffraction and scanning electron microscopy. The synthesized nanocomposite material was also tested for heterogeneous catalytic applications of 4-nitrophenol (4-NP) reduction into 4-aminophenol (4-AP). It was found to be successful in complete reduction of 4-NP with enhanced catalytic performance.

Lifting the Veil on ICT Gender Indicators in Africa

Gender equality has been identified as critical to the realisation of knowledge societies. This h... more Gender equality has been identified as critical to the realisation of knowledge societies. This has been reflected in policy commitments at both global and national levels. The increased take up of information and communication technologies (ICTs), particularly broadband, has increasingly been linked to economic growth and social inclusion. Yet, the uneven nature of such developments is widely known. In acknowledgement of this in relation to gender the World Summit on the Information Society in 2003 called on governments to find ways of providing opportunities for women to participate and empowering them to ensure their full and equal participation at all levels. Despite these rhetorical undertakings though there has been little systematic collection of sex disaggregated data on ICT access and use and even less that analyses the descriptive data that exists. Without such analysis, descriptive data is not only incomplete but can also mislead policymakers on the correct points of poli...

$Research paper thumbnail of Treatment-Refractory Insomnia in a Survivor of a Cancerous Brain Tumor$

Treatment-Refractory Insomnia in a Survivor of a Cancerous Brain Tumor

Psychiatric Annals, 2020

A quantile regression analysis of the conditional female wage distribution in post-apartheid South Africa

The democratisation of South Africa in 1994 brought about increased economic opportunity for labo... more The democratisation of South Africa in 1994 brought about increased economic opportunity for labour market participants. The impact of democratisation on the labour market outcomes of both males and females of various races has been studied extensively in terms of mean earnings. However, because of the heterogenous distribution of South African labour force participants, a mean analysis is not su cient. This paper investigates changes in the post-Apartheid conditional earnings distribution of women in South Africa of all races using conditional quantile regression analysis. Women are exclusively analysed because the labour market choices and constraints they face are unique. A two part model is estimated with the rst part correcting for sample selection into employment in a South African context. Then, quantile regression analysis is employed to parsimoniously describe the entire conditional wage distribution aiding the understanding of female labour force dynamics in South Africa. ...

Frequency and Etiology of Urinary Tract Infections in Neonatal Late Onset Sepsis

Objective: To determine the frequency and etiology of urinary tract infections in neonatal late o... more Objective: To determine the frequency and etiology of urinary tract infections in neonatal late onset sepsis. Study Design: Cross-sectional study. Place and Duration of Study: The study was carried out in neonatal unit, Shaikh Zayed Hospital, Lahore for six months period from January to June, 2014. Methodology: 175 neonates admitted in Neonatal Unit, Shaikh Zayad Hospital, Lahore through emergency, obstetric unit or outpatient department with late onset sepsis were included. Cases were selected by non-probability sampling technique. Results: Culture proven urinary tract infection (UTI) was present in 21.6% of late onset sepsis. The most common causative organism was Eschericha coli (84.21%) followed by Klebsiella (13.6%). No male, female predisposition was found in this study. Conclusion: All neonates with late onset sepsis should be investigated for urinary tract infection and most common causative organism is Escherichia coli.

Advertising Competence (for Personal Care Products) Endowed to Consumer Purchase Decisions

IO: Empirical Studies of Firms & Markets eJournal, 2015

Successful multinationals trigger to adopt the strategy of seek first to understand and then to b... more Successful multinationals trigger to adopt the strategy of seek first to understand and then to be understood, the same has been centric to the themes of this study that how the corporate houses are capturing the minds of present and future prospects with the aim of value generation with the binding relations to build the advertising competence in their promotional operations. The study involves six independent variables, which best prescribes the measurement parameters for advertising competence and their influential significance on dependent variable of consumer purchase decisions. The objective of the study is to screen out the most contributing variables; whereby a sample of 209 individuals is kept in consideration. The hypothesis regarding six independent variables were formed to evaluate the significant impact on dependent variable; from them four were found accepted and rest of two are rejected for this research. The application of SPSS-18 has been adopted by applying the tec...

Increased Oxidative Stress and Down Regulation of Endothelial Nitric Oxide Synthase ( Enos ) in the Kidney Attenuate the Responsiveness of Α 1 B Adrenergic Receptors in the Kidney of Rats with Left Ventricular Hypertrophy

Present study explored endothelial nitric oxide synthase/nitric oxide (eNOS/NO) pathway in the ki... more Present study explored endothelial nitric oxide synthase/nitric oxide (eNOS/NO) pathway in the kidney and role of α1B adrenergic receptor in the regulation of renal vasculature in the rats with left ventricular hypertrophy (LVH). LVH was induced by administering isoprenaline 5 mg/kg (s.c. 72 h. apart) and caffeine (62 mg/L in drinking water) for 14 days. Quantification of molecular expression of eNOS in kidney was performed by quantitative Real Time Polymerase Chain Reaction (qPCR). Renal vasoconstrictor responses were measured by administering noradrenaline (NA), phenylephrine (PE) and methoxamine (ME) in pre-drug phase, low dose and high dose phases of chloroethylclonidine (CEC), a selective of α1B adrenergic receptor antagonist. In the kidney of LVH male Wistar Kyoto (WKY) rats eNOS was significantly down regulated (p < 0.05) by 74% relative to Control WKY (taken as 100%). The high dose 5 CEC attenuated the vasoconstrictor responses to NA by 41%, PE by 43% and ME by 33% in the...

Antifungal activity of allelopathic plant extracts II: In vitro control of Fusarium moniliforme and F. oxysporum by aqueous extracts of four allelopathic grasses

The Employment Tax Incentive Scheme in South Africa: An Impact Assessment

The Employment Tax Incentive (ETI) is a South African wage subsidy programme introduced in 2014 a... more The Employment Tax Incentive (ETI) is a South African wage subsidy programme introduced in 2014 as a form of tax relief for firms hiring workers between the ages of 16 and 29, who earn less than R6 000 per month. Designed as a tool to combat high levels of youth unemployment, the results of studies estimating the effect of the ETI using survey data have shown little to no effect of the subsidy. This paper makes use of the administrative tax data made available through National Treasury in collaboration with the South African Revenue Service (SARS) to accurately identify and estimate the impact of the ETI using individual and firm-level tax returns for the period 2013 to 2016 using a Difference-in-Differences methodology combined with propensity score matching. The impact of the ETI is found to be statistically significant but small in magnitude: During a time when employment levels were decreasing, it is estimated that for every 1 job lost in a non-ETI claiming firm, ETI firms only ...

Polyvinyl Alcohol and Nano-Clay Based Solution Processed Packaging Coatings

Coatings

Cost-effective, clean, highly transparent, and flexible as well as a coatable packaging material ... more Cost-effective, clean, highly transparent, and flexible as well as a coatable packaging material is envisioned to solve or at least mitigate quality preservation issues of organic materials, originating from moisture interaction under ambient conditions. Liquid phase processing of packaging coatings using nano-clay and polyvinyl alcohol (PVOH) has been developed and reported. Detailed analysis of the developed coating revealed moisture permeability of 2.8 × 10−2 g·cm/m2·day at 40 °C and 85% relative humidity (RH), which is in close accordance with Bharadwaj’s theoretical permeability model. Moreover, the developed coatings are not only more than 90% transparent, when exposed to white light, but also exhibit excellent flexibility and even after going through 10,000 bending cycles maintained the same blocking effect against moisture.

Synthesis of Cr doped LiMnPO 4 cathode materials and investigation of their dielectric properties

International Journal of Energy Research

The Shallow Cognitive Map Hypothesis: A Hippocampal framework for Thought Disorder in Schizophrenia

Memories are not formed in isolation. They are associated and organized into relational knowledge... more Memories are not formed in isolation. They are associated and organized into relational knowledge structures that allow coherent thought. Failure to express such coherent thought is a key hallmark of Schizophrenia. Here we explore the hypothesis that thought disorder arises from disorganized Hippocampal cognitive maps. In doing so, we combine insights from two key lines of investigation, one concerning the neural signatures of cognitive mapping, and another that seeks to understand lower-level cellular mechanisms of cognition within a dynamical systems framework. Specifically, we propose that multiple distinct pathological pathways converge on the shallowing of Hippocampal attractors, giving rise to disorganized Hippocampal cognitive maps and driving thought disorder. We discuss the available evidence at the computational, behavioural, network and cellular levels. We also outline testable predictions from this framework including how it could unify major chemical and psychological t...

Surface charge on chitosan/cellulose nanowhiskers composite via functionalized and untreated carbon nanotube

Arabian Journal of Chemistry

Electro-Oxidation of Ammonia at Novel Ag2O−PrO2/γ-Al2O3 Catalysts

Coatings

An Ag2O(x)−PrO2(y)/γ-Al2O3 electrocatalyst series (X:Y is for Ag:Pr from 0 to 10) was synthesized... more An Ag2O(x)−PrO2(y)/γ-Al2O3 electrocatalyst series (X:Y is for Ag:Pr from 0 to 10) was synthesized, to use synthesized samples in electrochemical applications, a step in fuel cells advancements. Ag2O(x)−PrO2(y)/γ-Al2O3/Glassy-Carbon was investigated for electrochemical oxidation of ammonia in alkaline medium and proved to be highly effective, having high potential utility, as compared to commonly used Pt-based electrocatalysts. In this study, gamma alumina as catalytic support was synthesized via precipitation method, and stoichiometric wt/wt.% compositions of Ag2O−PrO2 were loaded on γ-Al2O3 by co-impregnation method. The desired phase of γ-Al2O3 and supported nanocatalysts was obtained after heat treatment at 800 and 600 °C, respectively. The successful loadings of Ag2O−PrO2 nanocatalysts on surface of γ-Al2O3 was determined by X-rays diffraction (XRD), Fourier-transform Infrared Spectroscopy (FTIR), and energy dispersive analysis (EDX). The nano-sized domain of the sample powders ...

Induction-remission response in pediatric acute lymphoblastic leukemia, Lahore protocol versus UKALL 2011 interim guidelines

Journal of the Pakistan Medical Association

OBJECTIVE To compare the outcome of induction-remission in acute lymphoblastic leukaemia patients... more OBJECTIVE To compare the outcome of induction-remission in acute lymphoblastic leukaemia patients treated according to two different guidelines. METHODS The descriptive retrospective cohort study was conducted at The Children's Hospital Lahore, Pakistan, and comprised clinical information sheets of acute lymphoblastic leukaemia patients from September 2014 to August 2015. Data regarding demographics, risk categorisation, rapid early response and induction-remission assessment was collected separately for Group 1 patients treated with Lahore protocol and Group 2 patients using United Kingdom acute lymphoblastic leukaemia-2011 interim guidelines. Data was analysed using SPSS version 20.0. RESULTS Of the 98 patients who had a median age of 6.4 years (interquartile range: 1.5-16 years), 48(49%) were in Group 1 and 50(51%) in Group 2. There were 14(29%) patients with standard risk in Group 1 while 34(71%) were high-risk. The corresponding numbers in Group 2 were 30(60%) and 20(40%) in Group 2. Rapid early response was noted in 18(37.5%) patients in Group 1 and 11(28%) in Group 2. Remission was achieved in 38(79%) patients in Group 1 and 36(72%) in Group 2. There was significant association of rapid early response with induction-remission in Group 2 (p<0.05) but not in Group 1 (p>0.05). CONCLUSIONS Induction-remission rate was comparable in the two treatment groups, but significant association of rapid early response with induction-remission was observed only in patients treated using United Kingdom acute lymphoblastic leukaemia-2011 interim guidelines.

Pharmacological importance of Nardostachys jatamansi DC: A potential therapeutic agent in different pathological ailments

Nardostachys jatamansi (Nj.Cr) DC. is an endangered, primitive and therapeutic agent in the famil... more Nardostachys jatamansi (Nj.Cr) DC. is an endangered, primitive and therapeutic agent in the family Valerianaceae. The herbs and rhizomes of this hairy, perennial, dwarf and herbaceous plant are used for medicinal purpose. Mostly herbs and rhizome are used for this hairy, perennial, dwarf and herbaceous plant. Nardostachys jatamansi has been reported to have many therapeutic activities like antifungal, antimicrobial, antioxidant, Hepatoprotective and cardioprotective properties. It is also useful in the management of insomnia and CNS disorders. The vasodilator, bronchodilator, spasmolytic and platelet aggregation inhibition activities of the plant have also been reported. In phytochemical analysis jatamansone, Nardostachone and actinidine have been reported to be present in the plant. This review article is summary of the potential benefits of this medicinal plant as reported in literature. The review also highlights the need for the use of this plant in Ayurveda system of medicine a...

Bio-fabrication of CuO nanoparticles using Leucophyllum frutescens leaf extract and investigation of their photocatalytic cationic dye degradation

Journal of Molecular Structure

What is the purpose of using email? Advantages of using email Reducing stress Cultural differences

How can Internet applications such as " email " be used by school teachers and students... more

Household Balance Sheets in South Africa

Funding for this research from the Department of Planning, Monitoring and Evaluation is gratefull... more

Genetic Improvement of Pulse Crops

Lanthanum-Zinc Binary Oxide Nanocomposite with Promising Heterogeneous Catalysis Performance for the Active Conversion of 4-Nitrophenol into 4-Aminophenol

Coatings

This work intended to enhance the unique and outstanding properties of lanthanum by synthesizing ... more This work intended to enhance the unique and outstanding properties of lanthanum by synthesizing its nanocomposite. A lanthanum-based nanocomposite was prepared by a simple and cost-effective “co-precipitation” method. Lanthanum nitrate (La (NO3)3) and zinc nitrate (Zn (NO3)2) were used as precursors. The lanthanum/zinc oxide nano composite formed was then calcined at 450 °C for 4 h in order to obtain a fine powder with size in the nano range of 1–100 nm. Characterization of the prepared catalyst was done by ultraviolet/visible spectroscopy, Fourier transform infrared spectroscopy, and photoluminescence. Crystallinity and morphology were found by X-ray diffraction and scanning electron microscopy. The synthesized nanocomposite material was also tested for heterogeneous catalytic applications of 4-nitrophenol (4-NP) reduction into 4-aminophenol (4-AP). It was found to be successful in complete reduction of 4-NP with enhanced catalytic performance.

Lifting the Veil on ICT Gender Indicators in Africa

Gender equality has been identified as critical to the realisation of knowledge societies. This h... more Gender equality has been identified as critical to the realisation of knowledge societies. This has been reflected in policy commitments at both global and national levels. The increased take up of information and communication technologies (ICTs), particularly broadband, has increasingly been linked to economic growth and social inclusion. Yet, the uneven nature of such developments is widely known. In acknowledgement of this in relation to gender the World Summit on the Information Society in 2003 called on governments to find ways of providing opportunities for women to participate and empowering them to ensure their full and equal participation at all levels. Despite these rhetorical undertakings though there has been little systematic collection of sex disaggregated data on ICT access and use and even less that analyses the descriptive data that exists. Without such analysis, descriptive data is not only incomplete but can also mislead policymakers on the correct points of poli...

$Research paper thumbnail of Treatment-Refractory Insomnia in a Survivor of a Cancerous Brain Tumor$

Treatment-Refractory Insomnia in a Survivor of a Cancerous Brain Tumor

Psychiatric Annals, 2020

A quantile regression analysis of the conditional female wage distribution in post-apartheid South Africa

The democratisation of South Africa in 1994 brought about increased economic opportunity for labo... more The democratisation of South Africa in 1994 brought about increased economic opportunity for labour market participants. The impact of democratisation on the labour market outcomes of both males and females of various races has been studied extensively in terms of mean earnings. However, because of the heterogenous distribution of South African labour force participants, a mean analysis is not su cient. This paper investigates changes in the post-Apartheid conditional earnings distribution of women in South Africa of all races using conditional quantile regression analysis. Women are exclusively analysed because the labour market choices and constraints they face are unique. A two part model is estimated with the rst part correcting for sample selection into employment in a South African context. Then, quantile regression analysis is employed to parsimoniously describe the entire conditional wage distribution aiding the understanding of female labour force dynamics in South Africa. ...

Frequency and Etiology of Urinary Tract Infections in Neonatal Late Onset Sepsis

Objective: To determine the frequency and etiology of urinary tract infections in neonatal late o... more Objective: To determine the frequency and etiology of urinary tract infections in neonatal late onset sepsis. Study Design: Cross-sectional study. Place and Duration of Study: The study was carried out in neonatal unit, Shaikh Zayed Hospital, Lahore for six months period from January to June, 2014. Methodology: 175 neonates admitted in Neonatal Unit, Shaikh Zayad Hospital, Lahore through emergency, obstetric unit or outpatient department with late onset sepsis were included. Cases were selected by non-probability sampling technique. Results: Culture proven urinary tract infection (UTI) was present in 21.6% of late onset sepsis. The most common causative organism was Eschericha coli (84.21%) followed by Klebsiella (13.6%). No male, female predisposition was found in this study. Conclusion: All neonates with late onset sepsis should be investigated for urinary tract infection and most common causative organism is Escherichia coli.

Advertising Competence (for Personal Care Products) Endowed to Consumer Purchase Decisions

IO: Empirical Studies of Firms & Markets eJournal, 2015

Successful multinationals trigger to adopt the strategy of seek first to understand and then to b... more Successful multinationals trigger to adopt the strategy of seek first to understand and then to be understood, the same has been centric to the themes of this study that how the corporate houses are capturing the minds of present and future prospects with the aim of value generation with the binding relations to build the advertising competence in their promotional operations. The study involves six independent variables, which best prescribes the measurement parameters for advertising competence and their influential significance on dependent variable of consumer purchase decisions. The objective of the study is to screen out the most contributing variables; whereby a sample of 209 individuals is kept in consideration. The hypothesis regarding six independent variables were formed to evaluate the significant impact on dependent variable; from them four were found accepted and rest of two are rejected for this research. The application of SPSS-18 has been adopted by applying the tec...

Increased Oxidative Stress and Down Regulation of Endothelial Nitric Oxide Synthase ( Enos ) in the Kidney Attenuate the Responsiveness of Α 1 B Adrenergic Receptors in the Kidney of Rats with Left Ventricular Hypertrophy

Present study explored endothelial nitric oxide synthase/nitric oxide (eNOS/NO) pathway in the ki... more Present study explored endothelial nitric oxide synthase/nitric oxide (eNOS/NO) pathway in the kidney and role of α1B adrenergic receptor in the regulation of renal vasculature in the rats with left ventricular hypertrophy (LVH). LVH was induced by administering isoprenaline 5 mg/kg (s.c. 72 h. apart) and caffeine (62 mg/L in drinking water) for 14 days. Quantification of molecular expression of eNOS in kidney was performed by quantitative Real Time Polymerase Chain Reaction (qPCR). Renal vasoconstrictor responses were measured by administering noradrenaline (NA), phenylephrine (PE) and methoxamine (ME) in pre-drug phase, low dose and high dose phases of chloroethylclonidine (CEC), a selective of α1B adrenergic receptor antagonist. In the kidney of LVH male Wistar Kyoto (WKY) rats eNOS was significantly down regulated (p < 0.05) by 74% relative to Control WKY (taken as 100%). The high dose 5 CEC attenuated the vasoconstrictor responses to NA by 41%, PE by 43% and ME by 33% in the...

Antifungal activity of allelopathic plant extracts II: In vitro control of Fusarium moniliforme and F. oxysporum by aqueous extracts of four allelopathic grasses

The Employment Tax Incentive Scheme in South Africa: An Impact Assessment

The Employment Tax Incentive (ETI) is a South African wage subsidy programme introduced in 2014 a... more The Employment Tax Incentive (ETI) is a South African wage subsidy programme introduced in 2014 as a form of tax relief for firms hiring workers between the ages of 16 and 29, who earn less than R6 000 per month. Designed as a tool to combat high levels of youth unemployment, the results of studies estimating the effect of the ETI using survey data have shown little to no effect of the subsidy. This paper makes use of the administrative tax data made available through National Treasury in collaboration with the South African Revenue Service (SARS) to accurately identify and estimate the impact of the ETI using individual and firm-level tax returns for the period 2013 to 2016 using a Difference-in-Differences methodology combined with propensity score matching. The impact of the ETI is found to be statistically significant but small in magnitude: During a time when employment levels were decreasing, it is estimated that for every 1 job lost in a non-ETI claiming firm, ETI firms only ...

Polyvinyl Alcohol and Nano-Clay Based Solution Processed Packaging Coatings

Coatings

Cost-effective, clean, highly transparent, and flexible as well as a coatable packaging material ... more Cost-effective, clean, highly transparent, and flexible as well as a coatable packaging material is envisioned to solve or at least mitigate quality preservation issues of organic materials, originating from moisture interaction under ambient conditions. Liquid phase processing of packaging coatings using nano-clay and polyvinyl alcohol (PVOH) has been developed and reported. Detailed analysis of the developed coating revealed moisture permeability of 2.8 × 10−2 g·cm/m2·day at 40 °C and 85% relative humidity (RH), which is in close accordance with Bharadwaj’s theoretical permeability model. Moreover, the developed coatings are not only more than 90% transparent, when exposed to white light, but also exhibit excellent flexibility and even after going through 10,000 bending cycles maintained the same blocking effect against moisture.

Synthesis of Cr doped LiMnPO 4 cathode materials and investigation of their dielectric properties

International Journal of Energy Research

The Shallow Cognitive Map Hypothesis: A Hippocampal framework for Thought Disorder in Schizophrenia

Memories are not formed in isolation. They are associated and organized into relational knowledge... more Memories are not formed in isolation. They are associated and organized into relational knowledge structures that allow coherent thought. Failure to express such coherent thought is a key hallmark of Schizophrenia. Here we explore the hypothesis that thought disorder arises from disorganized Hippocampal cognitive maps. In doing so, we combine insights from two key lines of investigation, one concerning the neural signatures of cognitive mapping, and another that seeks to understand lower-level cellular mechanisms of cognition within a dynamical systems framework. Specifically, we propose that multiple distinct pathological pathways converge on the shallowing of Hippocampal attractors, giving rise to disorganized Hippocampal cognitive maps and driving thought disorder. We discuss the available evidence at the computational, behavioural, network and cellular levels. We also outline testable predictions from this framework including how it could unify major chemical and psychological t...

Surface charge on chitosan/cellulose nanowhiskers composite via functionalized and untreated carbon nanotube

Arabian Journal of Chemistry

Electro-Oxidation of Ammonia at Novel Ag2O−PrO2/γ-Al2O3 Catalysts

Coatings

An Ag2O(x)−PrO2(y)/γ-Al2O3 electrocatalyst series (X:Y is for Ag:Pr from 0 to 10) was synthesized... more An Ag2O(x)−PrO2(y)/γ-Al2O3 electrocatalyst series (X:Y is for Ag:Pr from 0 to 10) was synthesized, to use synthesized samples in electrochemical applications, a step in fuel cells advancements. Ag2O(x)−PrO2(y)/γ-Al2O3/Glassy-Carbon was investigated for electrochemical oxidation of ammonia in alkaline medium and proved to be highly effective, having high potential utility, as compared to commonly used Pt-based electrocatalysts. In this study, gamma alumina as catalytic support was synthesized via precipitation method, and stoichiometric wt/wt.% compositions of Ag2O−PrO2 were loaded on γ-Al2O3 by co-impregnation method. The desired phase of γ-Al2O3 and supported nanocatalysts was obtained after heat treatment at 800 and 600 °C, respectively. The successful loadings of Ag2O−PrO2 nanocatalysts on surface of γ-Al2O3 was determined by X-rays diffraction (XRD), Fourier-transform Infrared Spectroscopy (FTIR), and energy dispersive analysis (EDX). The nano-sized domain of the sample powders ...

Induction-remission response in pediatric acute lymphoblastic leukemia, Lahore protocol versus UKALL 2011 interim guidelines

Journal of the Pakistan Medical Association

OBJECTIVE To compare the outcome of induction-remission in acute lymphoblastic leukaemia patients... more OBJECTIVE To compare the outcome of induction-remission in acute lymphoblastic leukaemia patients treated according to two different guidelines. METHODS The descriptive retrospective cohort study was conducted at The Children's Hospital Lahore, Pakistan, and comprised clinical information sheets of acute lymphoblastic leukaemia patients from September 2014 to August 2015. Data regarding demographics, risk categorisation, rapid early response and induction-remission assessment was collected separately for Group 1 patients treated with Lahore protocol and Group 2 patients using United Kingdom acute lymphoblastic leukaemia-2011 interim guidelines. Data was analysed using SPSS version 20.0. RESULTS Of the 98 patients who had a median age of 6.4 years (interquartile range: 1.5-16 years), 48(49%) were in Group 1 and 50(51%) in Group 2. There were 14(29%) patients with standard risk in Group 1 while 34(71%) were high-risk. The corresponding numbers in Group 2 were 30(60%) and 20(40%) in Group 2. Rapid early response was noted in 18(37.5%) patients in Group 1 and 11(28%) in Group 2. Remission was achieved in 38(79%) patients in Group 1 and 36(72%) in Group 2. There was significant association of rapid early response with induction-remission in Group 2 (p<0.05) but not in Group 1 (p>0.05). CONCLUSIONS Induction-remission rate was comparable in the two treatment groups, but significant association of rapid early response with induction-remission was observed only in patients treated using United Kingdom acute lymphoblastic leukaemia-2011 interim guidelines.