INGENIERÍA CIENCIAS FISICAS Y MATEMATICAS

ABSTRAa. The role of plasma glucose concentration in the regulation of endogenous glucose production in the human newborn was examined by infusing glucose at 2.6-4.6 mg/kg-min as a continuous infusion to eight normal term appropriate for gestational age infants, five preterm, and six small for gestational age infants. All infants were healthy, had no overt clinical problems and were studied 6 h after their last feed. Glucose production rates were measured during the basal state and during glucose infusion by tracer dilution using [6,62H2]glucose. The rate of glucose production during the basal state was similar in preterm and term appropriate for gestational age infants (appropriate for gestational age 3.53 f 0.32, preterm 3.49 -1 0.38 mg/kg. min, mean f SD), while it was higher in the small for gestational age infants (4.25 f 0.98, p < 0.03) as compared with appropriate for gestational age. During glucose infusion, the peak glucose concentration was related to the rate of glucose infusion. The endogenous glucose production rates during glucose infusion were variable in the three groups. However, a negative correlation between peak glucose concentration and endogenous glucose production rate was observed (r = -0.59, p = 0.006).

Requirements specification can often exhibit some shortcomings, regarding contents and organization of its partial specification elements. Sometimes, modularization is deficient, with modules dealing with too much information, or the same functionality being specified in different modules. Left unchecked, these inadequacies will propagate themselves to the subsequent phases of the software development and cause problems during maintenance. We have been able to identify a collection of typical deficiencies in the specification of structured documents and we propose a collection of refactorings that minimize or remove them. Doing this early in the development process increases requirements modularity and understandability. A case study is conducted to illustrate the use of these refactoring practices on two existing requirement documents.

Tropos is a framework which offers an approach to guide the development of multi-agent systems (MAS). It relies on the i* notation to describe both requirements and architectural design. However, the use of i* as an architectural description language (ADL) is not suitable, since it presents some limitations to capture all the information required for designing MAS architectures. Recognizing that the Unified Modeling Language 2.0 (UML) supports software architectural description, in this work we present an extension to the UML metamodel to capture the features of agency to support MAS modeling at the architectural level. In doing so, we define a notation to model MAS architectures. Furthermore, we provide a set of heuristics to describe MAS using our UML-based notation derived from an architectural description using i*. We illustrate our approach by modeling a Conference Management System.

Diseñar la zapata mostrada en la fig: Si la Columna de 70 x 50 lleva 10 fierros de 1" y transmite las cargas PD = 180 tn y PL = 100 tn . La capacidad portante admisible del suelo es qa = 2.5 kg/cm2 ; ademas fy = 4200kg/cm2 , fy = 280 kg/cm2 en la columna y fc = 210 kg/cm2 en la zapata