The ageing of filled and cross-linked ethylene propylene diene elastomer (EPDM) has been studied ... more The ageing of filled and cross-linked ethylene propylene diene elastomer (EPDM) has been studied under accelerated UV irradiation (l ! 290 nm) at 60 C, thermal ageing at 100 C and in nitric acid vapours for different time intervals. Hardness measurements were performed. DSC-thermoporosimetry was used to estimate the mesh size distribution and cross-linking densities for each ageing. The development of functional groups was monitored by ATR spectroscopy. An increase in oxidation with exposure time after the different types of ageing was observed. The thermal stability of EPDM was assessed by TGA and evolved volatile gases were identified using FTIR spectroscopy.
... Surface Modification of Polyethylene Shrojal M. Desai · RP Singh Polymer Chemistry Division, ... more ... Surface Modification of Polyethylene Shrojal M. Desai · RP Singh Polymer Chemistry Division, National Chemical Laboratory, 411008 Pune, India E-mail: [email protected] E-mail:[email protected] ... 232 Shrojal M. Desai · RP Singh Page 3. ...
An accelerated photodegradation study was performed on poly (2,2’-butylene-5,5’-bibenzimidazole) ... more An accelerated photodegradation study was performed on poly (2,2’-butylene-5,5’-bibenzimidazole) (PBIB) and poly (2,2’-phenylene-5,5’-bibenzimidazole) (PBIP) membranes to study their stability and mechanism of photo-degradation. Polymer membranes were irradiated by polychromatic UV rays having λ > 300 nm and were characterized by FT-IR spectroscopy, WAXD, DSC, SEM and contact angle measurements.
The municipal solid waste management is among the biggest challenges faced by the governments thr... more The municipal solid waste management is among the biggest challenges faced by the governments throughout the world. In context to the developing nations of Asia, which are usually overpopulated, the condition is worst. In order to deal with the millions of tons of solid waste generated every day, science and technology may provide the best solutions.
Clinica chimica acta; international journal of clinical chemistry, 2015
The circadian rhythm, as part of a broad time structure (chronome) of lipid peroxides and antioxi... more The circadian rhythm, as part of a broad time structure (chronome) of lipid peroxides and antioxidant defense mechanisms may relate to prevention, efficacy and management of preventive and curative chronotherapy. Fifty newly diagnosed patients with peptic ulcers, 30-45years of age, and 60 age-matched clinically healthy volunteers were synchronized for one week with diurnal activity from about 06:00 to about 22:00 and nocturnal rest. Breakfast was served around 08:30, lunch around 13:30 and dinner around 20:30. Drugs known to affect the free-radical systems were not taken. Blood samples were collected at 6-hour intervals for 24h under standardized, presumably 24-hour synchronized conditions. Plasma lipid peroxides, in the form of malondialdehyde (MDA), blood superoxide dismutase (SOD), glutathione peroxide (GPx), glutathione reductase (GR), catalase (CAT) activities, and serum total protein, albumin, ascorbic acid, total serum cholesterol, and HDL-cholesterol concentrations were dete...
Journal of Macromolecular Science-polymer Reviews, 1997
For many applications, the requirement is for a moderately priced polymer that can be molded easi... more For many applications, the requirement is for a moderately priced polymer that can be molded easily and exhibits adequate stiffness and toughness over a wide range of temperatures. The basic and simplest solution to this problem is to modify existing polymers that already possess many of the desired properties, but are lacking in toughness and stiffness. The approach can be
HIV infection is a major public health problem as it has dramatically increased the global burden... more HIV infection is a major public health problem as it has dramatically increased the global burden of disease. HIV infected patients experience a variety of clinical signs and symptoms. Our aim was to study the profile of clinical features and opportunistic infections in HIV infected adult subjects attending a tertiary care teaching hospital in north India. A total of 317 HIV infected patients attending the ART Centre and the ICTC of Chhatrapati Shahuji Maharaj Medical University, Lucknow were enrolled in the study, after obtaining informed consent. Clinical symptoms were recorded by direct questioning. Documented opportunistic infections were noted from patient records. 193/317 (60.9%) HIV positive patients were males and 124/317 (39.1%) females. Mean age of the patients was 34.2 ± 7.9 years. 271/317 (85.5%) patients were symptomatic. The common symptoms were weakness (65.6%), bodyache and joint pain (63.4%), lethargy and fatigue (62.5%), prolonged fever (53.3%), weight loss (47.6%), cough (44.5%), loss of appetite (44.2%) and chronic diarrhoea (40.1%). The overall proportion of symptomatic patients was significantly higher than the number with an etiologically documented opportunistic infections (32.5%). Pulmonary tuberculosis (30.9%) was the most frequently documented opportunistic infection. Affordable high quality laboratory diagnostic facilities for the diagnosis of opportunistic infections under the public health program will help to obtain an accurate picture of the range of opportunistic infections in HIV patients in India.
Background. Cardiomyocyte circadian rhythms and the circadian clock are known to coordinate myoca... more Background. Cardiomyocyte circadian rhythms and the circadian clock are known to coordinate myocardial function. In this review we discuss whether disruption of this mechanism plays a potential role in the etiology of cardiovascular diseases (CVDs), obesity and type 2 diabetes.
Alleles A1 and A2 of the Bos taurus CSN2 gene are the most common in a number of dairy cattle bre... more Alleles A1 and A2 of the Bos taurus CSN2 gene are the most common in a number of dairy cattle breeds. A genetic variant of the bovine β-casein gene includes A1 and B which encodes a histidine residue at codon 67, resulting in potential liberation of a bioactive peptide, β-casomorphin, upon digestion. This is an opium family substance, and has been associated with a large number of clinical implications in humans. Study includes amplification of bovine β-casein gene and further differentiation of variants A1 and A2 beta casein in cows. Conventional PCR was done to amplify β-casein gene in three hundred and one specimens. Further eighty amplicons were sent for sequencing. From the sequenced data, 24 were A2 homozygous (A2A2), 11were A1 homozygous (A1A1) and 37 heterozygous (A1A2). Allele discrimination in cows will be significant for the farmers, breeding programmes as well as for dairy industries as the milk variant determination will predict the outcome of the beta casein variants w...
All rights reserved. No part of contents of this paper may be reproduced or transmitted in any fo... more All rights reserved. No part of contents of this paper may be reproduced or transmitted in any form or by any means without the written permission of TTP, www.ttp.net. (ID: 66.249.72.248-14/04/11,19:18:01) ... 264 Ultra Clean Processing of Silicon Surfaces V
In this work, an attempt was made to synthesize a novel Chitosan-Mesoporous silica (CS-MS) hybrid... more In this work, an attempt was made to synthesize a novel Chitosan-Mesoporous silica (CS-MS) hybrid composite to design a drug delivery system based on ultrasound triggered stimuli-responsive smart release. The in-vitro drug release properties of both the Mesoporous Silica (MS) and Chitosan (CS) hybrids were investigated. Ibuprofen (Ibu) was used as a model drug. The results from powder X-Ray diffraction (XRD) patterns, and BET N2 adsorption isotherms exhibited that MS can accommodate drug molecules into the lumen of the channels and pores. Drug release, stimulated by temperature and pH of the release media was also investigated. We studied the Ultrasound (US) triggered release of Ibu in a simulated body fluid (pH 7.4). The results exhibited that US can be used as a non-invasive technique for drug release from polymeric materials. The enhancing effect of ultrasound on drug release is due to the Cavitation effect, without causing any significant destruction on the polymer morphology.
Alleles A1 and A2 of the Bos taurus CSN2 gene are the most common in a number of dairy cattle bre... more Alleles A1 and A2 of the Bos taurus CSN2 gene are the most common in a number of dairy cattle breeds. A genetic variant of the bovine β-casein gene includes A1 and B which encodes a histidine residue at codon 67, resulting in potential liberation of a bioactive peptide, βcasomorphin, upon digestion. This is an opium family substance, and has been associated with a large number of clinical implications in humans. Study includes amplification of bovine β-casein gene and further differentiation of variants A1 and A2 beta casein in cows. Conventional PCR was done to amplify β-casein gene in three hundred and one specimens. Further eighty amplicons were sent for sequencing. From the sequenced data, 24 were A2 homozygous (A2A2), 11were A1 homozygous (A1A1) and 37 heterozygous (A1A2). Allele discrimination in cows will be significant for the farmers, breeding programmes as well as for dairy industries as the milk variant determination will predict the outcome of the beta casein variants which are of utmost clinical relevance.
The hypolipidemic activity of Cassia tora (Chakvat, Chakunda) (Family: Caesalpiniaceae) seeds ext... more The hypolipidemic activity of Cassia tora (Chakvat, Chakunda) (Family: Caesalpiniaceae) seeds extract have been studied in alloxan-induced diabetic rats. In this model oral administration of seed extract (500 mg/kg bw.P.o.) for 15 days in diabetic-dyslipidemic rats exerted significant lipid lowering effect as assessed by the reversal of serum levels of total cholesterol, phospholipids, triglyceride, free fatty acids, protein and lipid peroxide. The decrease of lipids and apoprotein levels of Very Low Density Lipoprotein and Low Density Lipoprotein were followed by stimulation of plasma post-heparin lipolytic activity as well as lecithin cholesterol acyltransferase, hepatic superoxide dismutase, catalase, triglyceride lipase and lipoprotein lipase activities with increase in reduced glutathione. Lipid and apoprotein level of High Density Lipoprotein were also recovered partially on treatment with seeds extract. The results of the present study demonstrated antidyslipidemic and antiox...
According to one view of linguistic information (Karttunen, 1974; Stalnaker, 1974), a speaker can... more According to one view of linguistic information (Karttunen, 1974; Stalnaker, 1974), a speaker can convey contextually new information in one of two ways: (a) by asserting the content as new information; or (b) by presupposing the content as given information which would then have to be accommodated. This distinction predicts that it is conversationally more appropriate to assert implausible information rather than presuppose it (e.g., von Fintel, 2008; Heim, 1992; Stalnaker, 2002). A second view rejects the assumption that presuppositions are accommodated; instead, presuppositions are assimilated into asserted content and both are correspondingly open to challenge (e.g., Gazdar, 1979; van der Sandt, 1992). Under this view, we should not expect to find a difference in conversational appropriateness between asserting implausible information and presupposing it. To distinguish between these two views of linguistic information, we performed two self-paced reading experiments with an on-...
The ageing of filled and cross-linked ethylene propylene diene elastomer (EPDM) has been studied ... more The ageing of filled and cross-linked ethylene propylene diene elastomer (EPDM) has been studied under accelerated UV irradiation (l ! 290 nm) at 60 C, thermal ageing at 100 C and in nitric acid vapours for different time intervals. Hardness measurements were performed. DSC-thermoporosimetry was used to estimate the mesh size distribution and cross-linking densities for each ageing. The development of functional groups was monitored by ATR spectroscopy. An increase in oxidation with exposure time after the different types of ageing was observed. The thermal stability of EPDM was assessed by TGA and evolved volatile gases were identified using FTIR spectroscopy.
... Surface Modification of Polyethylene Shrojal M. Desai · RP Singh Polymer Chemistry Division, ... more ... Surface Modification of Polyethylene Shrojal M. Desai · RP Singh Polymer Chemistry Division, National Chemical Laboratory, 411008 Pune, India E-mail: [email protected] E-mail:[email protected] ... 232 Shrojal M. Desai · RP Singh Page 3. ...
An accelerated photodegradation study was performed on poly (2,2’-butylene-5,5’-bibenzimidazole) ... more An accelerated photodegradation study was performed on poly (2,2’-butylene-5,5’-bibenzimidazole) (PBIB) and poly (2,2’-phenylene-5,5’-bibenzimidazole) (PBIP) membranes to study their stability and mechanism of photo-degradation. Polymer membranes were irradiated by polychromatic UV rays having λ > 300 nm and were characterized by FT-IR spectroscopy, WAXD, DSC, SEM and contact angle measurements.
The municipal solid waste management is among the biggest challenges faced by the governments thr... more The municipal solid waste management is among the biggest challenges faced by the governments throughout the world. In context to the developing nations of Asia, which are usually overpopulated, the condition is worst. In order to deal with the millions of tons of solid waste generated every day, science and technology may provide the best solutions.
Clinica chimica acta; international journal of clinical chemistry, 2015
The circadian rhythm, as part of a broad time structure (chronome) of lipid peroxides and antioxi... more The circadian rhythm, as part of a broad time structure (chronome) of lipid peroxides and antioxidant defense mechanisms may relate to prevention, efficacy and management of preventive and curative chronotherapy. Fifty newly diagnosed patients with peptic ulcers, 30-45years of age, and 60 age-matched clinically healthy volunteers were synchronized for one week with diurnal activity from about 06:00 to about 22:00 and nocturnal rest. Breakfast was served around 08:30, lunch around 13:30 and dinner around 20:30. Drugs known to affect the free-radical systems were not taken. Blood samples were collected at 6-hour intervals for 24h under standardized, presumably 24-hour synchronized conditions. Plasma lipid peroxides, in the form of malondialdehyde (MDA), blood superoxide dismutase (SOD), glutathione peroxide (GPx), glutathione reductase (GR), catalase (CAT) activities, and serum total protein, albumin, ascorbic acid, total serum cholesterol, and HDL-cholesterol concentrations were dete...
Journal of Macromolecular Science-polymer Reviews, 1997
For many applications, the requirement is for a moderately priced polymer that can be molded easi... more For many applications, the requirement is for a moderately priced polymer that can be molded easily and exhibits adequate stiffness and toughness over a wide range of temperatures. The basic and simplest solution to this problem is to modify existing polymers that already possess many of the desired properties, but are lacking in toughness and stiffness. The approach can be
HIV infection is a major public health problem as it has dramatically increased the global burden... more HIV infection is a major public health problem as it has dramatically increased the global burden of disease. HIV infected patients experience a variety of clinical signs and symptoms. Our aim was to study the profile of clinical features and opportunistic infections in HIV infected adult subjects attending a tertiary care teaching hospital in north India. A total of 317 HIV infected patients attending the ART Centre and the ICTC of Chhatrapati Shahuji Maharaj Medical University, Lucknow were enrolled in the study, after obtaining informed consent. Clinical symptoms were recorded by direct questioning. Documented opportunistic infections were noted from patient records. 193/317 (60.9%) HIV positive patients were males and 124/317 (39.1%) females. Mean age of the patients was 34.2 ± 7.9 years. 271/317 (85.5%) patients were symptomatic. The common symptoms were weakness (65.6%), bodyache and joint pain (63.4%), lethargy and fatigue (62.5%), prolonged fever (53.3%), weight loss (47.6%), cough (44.5%), loss of appetite (44.2%) and chronic diarrhoea (40.1%). The overall proportion of symptomatic patients was significantly higher than the number with an etiologically documented opportunistic infections (32.5%). Pulmonary tuberculosis (30.9%) was the most frequently documented opportunistic infection. Affordable high quality laboratory diagnostic facilities for the diagnosis of opportunistic infections under the public health program will help to obtain an accurate picture of the range of opportunistic infections in HIV patients in India.
Background. Cardiomyocyte circadian rhythms and the circadian clock are known to coordinate myoca... more Background. Cardiomyocyte circadian rhythms and the circadian clock are known to coordinate myocardial function. In this review we discuss whether disruption of this mechanism plays a potential role in the etiology of cardiovascular diseases (CVDs), obesity and type 2 diabetes.
Alleles A1 and A2 of the Bos taurus CSN2 gene are the most common in a number of dairy cattle bre... more Alleles A1 and A2 of the Bos taurus CSN2 gene are the most common in a number of dairy cattle breeds. A genetic variant of the bovine β-casein gene includes A1 and B which encodes a histidine residue at codon 67, resulting in potential liberation of a bioactive peptide, β-casomorphin, upon digestion. This is an opium family substance, and has been associated with a large number of clinical implications in humans. Study includes amplification of bovine β-casein gene and further differentiation of variants A1 and A2 beta casein in cows. Conventional PCR was done to amplify β-casein gene in three hundred and one specimens. Further eighty amplicons were sent for sequencing. From the sequenced data, 24 were A2 homozygous (A2A2), 11were A1 homozygous (A1A1) and 37 heterozygous (A1A2). Allele discrimination in cows will be significant for the farmers, breeding programmes as well as for dairy industries as the milk variant determination will predict the outcome of the beta casein variants w...
All rights reserved. No part of contents of this paper may be reproduced or transmitted in any fo... more All rights reserved. No part of contents of this paper may be reproduced or transmitted in any form or by any means without the written permission of TTP, www.ttp.net. (ID: 66.249.72.248-14/04/11,19:18:01) ... 264 Ultra Clean Processing of Silicon Surfaces V
In this work, an attempt was made to synthesize a novel Chitosan-Mesoporous silica (CS-MS) hybrid... more In this work, an attempt was made to synthesize a novel Chitosan-Mesoporous silica (CS-MS) hybrid composite to design a drug delivery system based on ultrasound triggered stimuli-responsive smart release. The in-vitro drug release properties of both the Mesoporous Silica (MS) and Chitosan (CS) hybrids were investigated. Ibuprofen (Ibu) was used as a model drug. The results from powder X-Ray diffraction (XRD) patterns, and BET N2 adsorption isotherms exhibited that MS can accommodate drug molecules into the lumen of the channels and pores. Drug release, stimulated by temperature and pH of the release media was also investigated. We studied the Ultrasound (US) triggered release of Ibu in a simulated body fluid (pH 7.4). The results exhibited that US can be used as a non-invasive technique for drug release from polymeric materials. The enhancing effect of ultrasound on drug release is due to the Cavitation effect, without causing any significant destruction on the polymer morphology.
Alleles A1 and A2 of the Bos taurus CSN2 gene are the most common in a number of dairy cattle bre... more Alleles A1 and A2 of the Bos taurus CSN2 gene are the most common in a number of dairy cattle breeds. A genetic variant of the bovine β-casein gene includes A1 and B which encodes a histidine residue at codon 67, resulting in potential liberation of a bioactive peptide, βcasomorphin, upon digestion. This is an opium family substance, and has been associated with a large number of clinical implications in humans. Study includes amplification of bovine β-casein gene and further differentiation of variants A1 and A2 beta casein in cows. Conventional PCR was done to amplify β-casein gene in three hundred and one specimens. Further eighty amplicons were sent for sequencing. From the sequenced data, 24 were A2 homozygous (A2A2), 11were A1 homozygous (A1A1) and 37 heterozygous (A1A2). Allele discrimination in cows will be significant for the farmers, breeding programmes as well as for dairy industries as the milk variant determination will predict the outcome of the beta casein variants which are of utmost clinical relevance.
The hypolipidemic activity of Cassia tora (Chakvat, Chakunda) (Family: Caesalpiniaceae) seeds ext... more The hypolipidemic activity of Cassia tora (Chakvat, Chakunda) (Family: Caesalpiniaceae) seeds extract have been studied in alloxan-induced diabetic rats. In this model oral administration of seed extract (500 mg/kg bw.P.o.) for 15 days in diabetic-dyslipidemic rats exerted significant lipid lowering effect as assessed by the reversal of serum levels of total cholesterol, phospholipids, triglyceride, free fatty acids, protein and lipid peroxide. The decrease of lipids and apoprotein levels of Very Low Density Lipoprotein and Low Density Lipoprotein were followed by stimulation of plasma post-heparin lipolytic activity as well as lecithin cholesterol acyltransferase, hepatic superoxide dismutase, catalase, triglyceride lipase and lipoprotein lipase activities with increase in reduced glutathione. Lipid and apoprotein level of High Density Lipoprotein were also recovered partially on treatment with seeds extract. The results of the present study demonstrated antidyslipidemic and antiox...
According to one view of linguistic information (Karttunen, 1974; Stalnaker, 1974), a speaker can... more According to one view of linguistic information (Karttunen, 1974; Stalnaker, 1974), a speaker can convey contextually new information in one of two ways: (a) by asserting the content as new information; or (b) by presupposing the content as given information which would then have to be accommodated. This distinction predicts that it is conversationally more appropriate to assert implausible information rather than presuppose it (e.g., von Fintel, 2008; Heim, 1992; Stalnaker, 2002). A second view rejects the assumption that presuppositions are accommodated; instead, presuppositions are assimilated into asserted content and both are correspondingly open to challenge (e.g., Gazdar, 1979; van der Sandt, 1992). Under this view, we should not expect to find a difference in conversational appropriateness between asserting implausible information and presupposing it. To distinguish between these two views of linguistic information, we performed two self-paced reading experiments with an on-...
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