Our study was undertaken to evaluate the levels of thrombin-activatable fibrinolysis inhibitor (T... more Our study was undertaken to evaluate the levels of thrombin-activatable fibrinolysis inhibitor (TAFI) antigen and also its relationship with other hemostasis markers in a group of patients affected with polycystic ovary syndrome (PCOS)-under Diane-35 (ethinyl estradiol 0.035 mg/cyproterone acetate 2 mg) treatment or not-as compared with a group of healthy controls. Forty-two women with PCOS and 30 age-matched healthy controls were involved in the study. Group A were on Diane-35 for at least 6 months; group B did not take any drug; group C served as a control group. TAFI antigen levels of groups A and B were significantly higher than in controls, but no difference was observed between them. All of the other coagulation and fibrinolysis parameters (including prothrombin time, activated partial thromboplastin time, fibrinogen and D-dimer) were comparable between the three groups. The evidence presented herein suggests that women with PCOS have impaired fibrinolysis, as reflected by increased TAFI. This impairment can contribute to the risk of cardiovascular disease in PCOS. Elucidation of the modifiable mechanisms in PCOS can represent an opportunity for preventive therapy of the cardiovascular risks associated with PCOS.
Physical and chemical parameters of medlar fruit are necessary for the design of equipment to han... more Physical and chemical parameters of medlar fruit are necessary for the design of equipment to handle, harvest, process, store the product and nutrition values. In this study, the medlar (Mespilus germanica L.) fruit was studied to determine for some physical (dimension, geometric mean diameter, sphericity, bulk density, fruit density, volume, hardness and porosity) and chemical (moisture, crude protein, oil, energy, fibre and ash, pH, acidity, water-soluble extract, alcohol-soluble extract and ether-soluble extracts) properties. Moisture, crude oil, protein, fibre, energy, and ash, acidity, pH, water-soluble extract, alcohol-soluble and ether-soluble were found to be 72.15%, 4.09%, 3.71%, 11.4%, 16.5 kcal/g, 1.96%, 0.28%, 4.26, 68.89%, 53.35% and 2.41% (dry basis (except for pH)), respectively. Inductively coupled plasma atomic emission spectrometer (ICP-AES) determined the mineral content of medlar fruit. Potassium (8052.91 mg/kg) was present in the highest concentration, following S, Ca, B and P. Also, K, S, Ca, B and S were present in higher concentrations, and traces of Cr, Ti and V were also determined. The fruit mass, diameter, volume, geometric mean diameter, sphericity and projected area were measured as 11.98 g, 27.68 mm, 13.68 cm3, 28.86 mm, 0.92, and 9.25 cm2, respectively. The changes in physical and chemical properties of fruits having about the same size were probably due to environmental conditions in conjunction with the analytical methods used. Consequently, the analytical values showed rich nutritional properties and mineral contents of medlar fruits. Also, the mineral content of medlar fruit is of great interest. In addition, knowledge of the physical properties of equipment used in planting, harvesting, transportation, storage and processing of matured medlar fruits is very important.
Physical and chemical parameters of medlar fruit are necessary for the design of equipment to han... more Physical and chemical parameters of medlar fruit are necessary for the design of equipment to handle, harvest, process, store the product and nutrition values. In this study, the medlar (Mespilus germanica L.) fruit was studied to determine for some physical (dimension, geometric mean diameter, sphericity, bulk density, fruit density, volume, hardness and porosity) and chemical (moisture, crude protein, oil, energy, fibre and ash, pH, acidity, water-soluble extract, alcohol-soluble extract and ether-soluble extracts) properties. Moisture, crude oil, protein, fibre, energy, and ash, acidity, pH, water-soluble extract, alcohol-soluble and ether-soluble were found to be 72.15%, 4.09%, 3.71%, 11.4%, 16.5 kcal/g, 1.96%, 0.28%, 4.26, 68.89%, 53.35% and 2.41% (dry basis (except for pH)), respectively. Inductively coupled plasma atomic emission spectrometer (ICP-AES) determined the mineral content of medlar fruit. Potassium (8052.91 mg/kg) was present in the highest concentration, following S, Ca, B and P. Also, K, S, Ca, B and S were present in higher concentrations, and traces of Cr, Ti and V were also determined. The fruit mass, diameter, volume, geometric mean diameter, sphericity and projected area were measured as 11.98 g, 27.68 mm, 13.68 cm 3 , 28.86 mm, 0.92, and 9.25 cm 2 , respectively. The changes in physical and chemical properties of fruits having about the same size were probably due to environmental conditions in conjunction with the analytical methods used. Consequently, the analytical values showed rich nutritional properties and mineral contents of medlar fruits. Also, the mineral content of medlar fruit is of great interest. In addition, knowledge of the physical properties of equipment used in planting, harvesting, transportation, storage and processing of matured medlar fruits is very important.
Our study was undertaken to evaluate the levels of thrombin-activatable fibrinolysis inhibitor (T... more Our study was undertaken to evaluate the levels of thrombin-activatable fibrinolysis inhibitor (TAFI) antigen and also its relationship with other hemostasis markers in a group of patients affected with polycystic ovary syndrome (PCOS)-under Diane-35 (ethinyl estradiol 0.035 mg/cyproterone acetate 2 mg) treatment or not-as compared with a group of healthy controls. Forty-two women with PCOS and 30 age-matched healthy controls were involved in the study. Group A were on Diane-35 for at least 6 months; group B did not take any drug; group C served as a control group. TAFI antigen levels of groups A and B were significantly higher than in controls, but no difference was observed between them. All of the other coagulation and fibrinolysis parameters (including prothrombin time, activated partial thromboplastin time, fibrinogen and D-dimer) were comparable between the three groups. The evidence presented herein suggests that women with PCOS have impaired fibrinolysis, as reflected by increased TAFI. This impairment can contribute to the risk of cardiovascular disease in PCOS. Elucidation of the modifiable mechanisms in PCOS can represent an opportunity for preventive therapy of the cardiovascular risks associated with PCOS.
Physical and chemical parameters of medlar fruit are necessary for the design of equipment to han... more Physical and chemical parameters of medlar fruit are necessary for the design of equipment to handle, harvest, process, store the product and nutrition values. In this study, the medlar (Mespilus germanica L.) fruit was studied to determine for some physical (dimension, geometric mean diameter, sphericity, bulk density, fruit density, volume, hardness and porosity) and chemical (moisture, crude protein, oil, energy, fibre and ash, pH, acidity, water-soluble extract, alcohol-soluble extract and ether-soluble extracts) properties. Moisture, crude oil, protein, fibre, energy, and ash, acidity, pH, water-soluble extract, alcohol-soluble and ether-soluble were found to be 72.15%, 4.09%, 3.71%, 11.4%, 16.5 kcal/g, 1.96%, 0.28%, 4.26, 68.89%, 53.35% and 2.41% (dry basis (except for pH)), respectively. Inductively coupled plasma atomic emission spectrometer (ICP-AES) determined the mineral content of medlar fruit. Potassium (8052.91 mg/kg) was present in the highest concentration, following S, Ca, B and P. Also, K, S, Ca, B and S were present in higher concentrations, and traces of Cr, Ti and V were also determined. The fruit mass, diameter, volume, geometric mean diameter, sphericity and projected area were measured as 11.98 g, 27.68 mm, 13.68 cm3, 28.86 mm, 0.92, and 9.25 cm2, respectively. The changes in physical and chemical properties of fruits having about the same size were probably due to environmental conditions in conjunction with the analytical methods used. Consequently, the analytical values showed rich nutritional properties and mineral contents of medlar fruits. Also, the mineral content of medlar fruit is of great interest. In addition, knowledge of the physical properties of equipment used in planting, harvesting, transportation, storage and processing of matured medlar fruits is very important.
Physical and chemical parameters of medlar fruit are necessary for the design of equipment to han... more Physical and chemical parameters of medlar fruit are necessary for the design of equipment to handle, harvest, process, store the product and nutrition values. In this study, the medlar (Mespilus germanica L.) fruit was studied to determine for some physical (dimension, geometric mean diameter, sphericity, bulk density, fruit density, volume, hardness and porosity) and chemical (moisture, crude protein, oil, energy, fibre and ash, pH, acidity, water-soluble extract, alcohol-soluble extract and ether-soluble extracts) properties. Moisture, crude oil, protein, fibre, energy, and ash, acidity, pH, water-soluble extract, alcohol-soluble and ether-soluble were found to be 72.15%, 4.09%, 3.71%, 11.4%, 16.5 kcal/g, 1.96%, 0.28%, 4.26, 68.89%, 53.35% and 2.41% (dry basis (except for pH)), respectively. Inductively coupled plasma atomic emission spectrometer (ICP-AES) determined the mineral content of medlar fruit. Potassium (8052.91 mg/kg) was present in the highest concentration, following S, Ca, B and P. Also, K, S, Ca, B and S were present in higher concentrations, and traces of Cr, Ti and V were also determined. The fruit mass, diameter, volume, geometric mean diameter, sphericity and projected area were measured as 11.98 g, 27.68 mm, 13.68 cm 3 , 28.86 mm, 0.92, and 9.25 cm 2 , respectively. The changes in physical and chemical properties of fruits having about the same size were probably due to environmental conditions in conjunction with the analytical methods used. Consequently, the analytical values showed rich nutritional properties and mineral contents of medlar fruits. Also, the mineral content of medlar fruit is of great interest. In addition, knowledge of the physical properties of equipment used in planting, harvesting, transportation, storage and processing of matured medlar fruits is very important.
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