Papers by nooshin asadmasjedi
International journal of medical toxicology and forensic medicine, 2015
Background : Scorpion sting is a health problem in the world including tropical regions of Iran a... more Background : Scorpion sting is a health problem in the world including tropical regions of Iran as in rural region of Khuzestan province. Therefore appropriate diagnosis and treatment has a special aspect. The aim of present study was to evaluation of demographic status and clinical aspect of scorpion sting patient due to better prevention and treatment and diagnosis. Methods: This survey done by analyzing medical records of patients suffered from scorpion sting, hospitalize in Razi hospital in Khuzestan province (southwest of Iran) among 2006-2010. Patient information have been extracted and inserted in the inquiry form and data were analyzed by SPSS software. Results: In the present study 1922 patients have been studied. Proportion of females stung by scorpion to male was 1.29 to 1. Place of sting were mostly trunk (693 cases =36.05%) and remains were on other part of body. About 419 persons (21.8 %) have come to hospital about 6-24 hours after being stung and 708 people (36.83 %)...
Background Acetaminophen (APAP) is known as a safe drug for the relief of fever and pain at thera... more Background Acetaminophen (APAP) is known as a safe drug for the relief of fever and pain at therapeutic levels. However, APAP toxicity is considered as the most general cause of acute hepatic damage. This research aimed to evaluate the protective effects of Protocatechuic acid (PCA), as an antioxidant, on the APAP-induced liver toxicity in mice. Methods In this regard, we treated male ICR mice with 40, 80, and 160 mg/kg PCA followed by 300 mg/kg APAP 1 h later for 7 days. By passing 24 h from the APAP administration, they were sacrificed, their Liver was dissected, and blood samples were collected for the evaluation of liver function. Results The results show that APAP-overdose (300mg/kg, IP) could lead to acute liver injury in mice, which is characterized by a rise in serum liver function tests (AST, ALT), pathological changes, and a decline in the antioxidant defense system. In addition, hepatic MDA levels, as the end product of lipid peroxidation, have increased, while the antiox...
Journal of Family & Reproductive Health
Objective: Environmental stressors such as physical and chemical factors can have a destructive t... more Objective: Environmental stressors such as physical and chemical factors can have a destructive testicular function. The present study aimed to determine the effect of concomitant exposure to lead and noise on testicular tissue in male rats. Materials and methods: Twenty male Wistar rats (250-300 g, 12-13wk) were divided into four groups (n=5/each): 1) Control group, 2) Lead group treated with 4 mg/kg lead acetate by gavage for 30 days, 3) Noise group exposed to 4 kHz octave band at 105 dBA for eight hrs./ day for 30 days, and 4) the exposed group to lead plus noise concurrently. The testes' weight was measured, and testes abnormalities were assessed after staining with Hematoxylin and Eosin. Results: The results showed that the weight of testes in experimental groups was significantly decreased compared with the control group (p<0.0001). Also indicated edema, degeneration and necrotic cell debris in the lumen, congestion and atrophy of seminiferous tubule in rat testes tissu...
Biomedicine & Pharmacotherapy
MOJ Bioequivalence & Bioavailability
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Papers by nooshin asadmasjedi