Papers by narges ebrahimi
Background: Fampridine is the only drug that was approved by US Food and Drug Administration (FDA... more Background: Fampridine is the only drug that was approved by US Food and Drug Administration (FDA) for patients with multiple sclerosis to improve their movement and has exhibited a clinically significant improvement in gait function in subset of multiple sclerosis patients with Expanded Disability Status scale (ESDSS) from 4 to 7. Nevertheless, this drug has been reported to possess some adverse effects like seizure due to its pharmacological features. The aim of this study was to evaluate the incidence rate of post-medication side effects of Fampridine on multiple sclerosis patients. Method: This prospective cohort study includes MS patients aged between 18 years to 65 years, referred to neurology clinic of Kashani hospital from April 2022 to October 2022, all with administration of Fampridine (10mg tablet every 12 hours according to the product specifications) Safety in these patients is monitored through monthly side effects checklist questions during six months of screening. SP...
BMC Women's Health
Objective To estimate the pooled prevalence of sexual dysfunction (SD) in women with multiple scl... more Objective To estimate the pooled prevalence of sexual dysfunction (SD) in women with multiple sclerosis (MS). Methods We systematically searched PubMed, Scopus, EMBASE, Web of Science, and google scholar and also gray literature up to October 2021. The search strategy includes: (“Multiple Sclerosis” OR “MS” OR “Disseminated Sclerosis” OR (Disseminated AND Sclerosis) OR (Sclerosis AND Multiple)) AND (“Sexual Dysfunction” OR (Sexual AND Dysfunction) OR (Sexual AND Dysfunctions) OR (Sexual AND Disorders) OR (Sexual AND Disorder) OR “Sexual Dysfunctions” OR “Sexual Disorders” OR “Sexual Disorder” OR “Psychosexual Dysfunctions” OR (Dysfunction AND Psychosexual) OR (Dysfunctions AND Psychosexual) OR “Psychosexual Dysfunction” OR “Psychosexual Disorders” OR (Disorder AND Psychosexual) OR (Disorders AND Psychosexual) OR “Psychosexual Disorder” OR “Hypoactive Sexual Desire Disorder” OR “Sexual Aversion Disorder” OR (Aversion Disorders AND Sexual) OR (Disorders AND Sexual Aversion) OR “Sexual...
The relationship between retinal layer thickness and cognition in patients with multiple sclerosis: A systematic review of current literature
Current Journal of Neurology
Background: This study was conducted to evaluate the relationship between retinal layer thickness... more Background: This study was conducted to evaluate the relationship between retinal layer thickness (RLT) and cognition in patients with multiple sclerosis (MS). Methods: We searched PubMed, Scopus, Embase, Web of Science, and Google Scholar. The search strategy included the MeSH and text words as [“ora serrata” OR “retina” OR (“coherence tomography” AND “optical”) OR “OCT tomography” OR (tomography AND OCT) OR “optical coherence tomography” OR “OCT” OR “retinal thickness” OR “inner plexiform layer” OR “nerve fiber layer” OR “ganglion cell layer” OR “inner nuclear layer” OR “outer plexiform layer” OR “outer nuclear layer” OR “external limiting membrane” OR “inner segment layer” OR “outer segment layer” OR “retinal pigment epithelium”] AND [“cognition”* OR “cognitive function”* OR (function* AND cognitive)] AND [(sclerosis AND multiple) OR (sclerosis AND disseminated) OR "disseminated sclerosis" OR "multiple sclerosis" OR "acute fulminating"]. Results: The...
Advances in nanotechnology versus stem cell therapy for the theranostics of multiple sclerosis disease
Applied Nanoscience
CNS demyelinating disease following inactivated or viral vector SARS-CoV-2 vaccines: A case series
Vaccine
Multiple Sclerosis International
Background. Celiac disease (CD) is an autoimmune disease, and its prevalence reported variously i... more Background. Celiac disease (CD) is an autoimmune disease, and its prevalence reported variously in different studies. The goal of this study is to evaluate the pooled prevalence of CD in subjects with MS. Methods. PubMed, Scopus, EMBASE, Web of Science, and Google Scholar along with gray literature were systematically searched. The search included all relevant studies which were published up to October 2022. Two researchers independently searched all databases and also references of included studies. Results. We found 8211 articles by literature search, and after deleting duplicates, 5594 remained. Fifteen articles remained for meta-analysis. Totally, 31418 patients were evaluated, and the total number of possible/confirmed cases was 124. Studies were published between 2004 and 2020, and the most published studies were from Italy. Five studies provided information regarding controls. The total number of controls was 22394, of whom 22 had CD. Mean age ranged from 35 to 55 years. The ...
The prevalence of cancer in patients with multiple sclerosis (MS) who received rituximab: a systematic review and meta-analysis
Neurología (English Edition)
Stem cell treatment and cerebral palsy: A Systematic review and meta-analysis
Current stem cell research & therapy, Dec 1, 2022
Aptamer-conjugated carbon-based nanomaterials for cancer and bacteria theranostics: A review
Chemico-Biological Interactions
The prevalence of restless legs syndrome (RLS) in patients with multiple sclerosis (MS): a systematic review and meta-analysis—an update
Neurological Sciences
Hearing loss among patients with multiple sclerosis (PwMS): A systematic review and meta-analysis
Multiple Sclerosis and Related Disorders, 2022
Objectives: Dysphagia is a major comorbidity observed in patients with multiple sclerosis, yet di... more Objectives: Dysphagia is a major comorbidity observed in patients with multiple sclerosis, yet different prevalence rates are reported for it. Therefore, we have designed this systematic review to estimate the pooled prevalence of dysphagia in patients with MS. Method: We searched PubMed, Scopus, EMBASE, Web of Science, and gray literature including references from the identified studies, reviews studies, and conference abstracts which were published up to February 2021. Articles that were relevant to our topic and could provide information regarding the prevalence of dysphagia among MS patients were included; however, articles with self-report screening strategies were excluded. Results: The literature search found 1993 articles. After eliminating duplicates, 1272 articles remained. Sixteen abstract conference papers were included for final analysis. A total of 10846 MS cases and 4913 MS patients with dysphagia included in the analysis. The pooled prevalence of dysphagia in the inc...
Objectives: Olfactory dysfunction is a major comorbidity observed in patients with multiple scler... more Objectives: Olfactory dysfunction is a major comorbidity observed in patients with multiple sclerosis, yet different prevalence rates are reported for it. Therefore, we have designed this systematic review to estimate the pooled prevalence of olfactory dysfunction in patients with MS. To our knowledge, this is the first systematic review and meta-analysis on the prevalence of olfactory dysfunction in MS patients. Method: We searched PubMed, Scopus, EMBASE, Web of Science, ProQuest, and gray literature including references from the identified studies, review studies, and conference abstracts which were published up to January 2021. Articles that were relevant to our topic and could provide information regarding the prevalence of olfactory dysfunction, or the scores of smell threshold, discrimination, or identification (TDI scores) among MS patients and healthy individuals were included; however, articles published before 1990 and after the end of 2020 were excluded. Results: The lite...
Neurological Sciences
Background Patients with Parkinson's disease (PD) are at higher risk of COVID-19 infection as mos... more Background Patients with Parkinson's disease (PD) are at higher risk of COVID-19 infection as most of them are at older age. The goal of this study is to update the pooled prevalence of COVID-19 infection in patients with PD. Methods Two researchers systematically searched PubMed, Scopus, EMBASE, Web of Science, Google Scholar, and also gray literature including references of the included studies which were published before September 2021. We extracted data regarding the total number of participants, first author, publication year, the country of origin, mean age, number with COVID-19, symptoms, hospitalization, and death. Results We found 1693 articles by literature search; after deleting duplicates, 798 remained. Thirty articles remained for meta-analysis. The pooled prevalence of COVID-19 infection in PD cases was 5% (95%CI: 4-6%) (I 2 = 98.1%, P < 0.001). The pooled prevalence of fever in cases with PD was 4% (95%CI: 2-6%) (I 2 = 96%, P < 0.001). The pooled prevalence of cough in cases with PD was 3% (95%CI: 2-4%) (I 2 = 95.9%, P < 0.001). The pooled prevalence of hospitalization in cases with COVID-19 infection was 49% (95%CI: 29-52%) (I 2 : 93.5%, P < 0.001). The pooled prevalence of mortality in COVID-19 cases was 12% (95%CI: 10-14%) (I 2 = 97.6%, P < 0.001). Conclusion The results of this systematic review and meta-analysis show that the pooled prevalence of COVID-19 infection in PD cases is 5% besides hospitalization and mortality rates which are 49% and 12%.
COVID-19 Susceptibility and Outcomes among Patients with Neuromyelitis Optica Spectrum Disorder (NMOSD): A Systematic Review and Meta-Analysis
Multiple Sclerosis and Related Disorders
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Papers by narges ebrahimi