Sulfur-containing compounds are present in many important living organisms.(1) One important clas... more Sulfur-containing compounds are present in many important living organisms.(1) One important class of heterocyclic compounds which has the etheric sulfur atom is the five-membered thiazole ring.(2) As they possess several biological properties, thiazole derivatives are the main ...
The geometries, relative stabilities, proton af®nities for tautomers of 1, 3,6,10,12,15-hexamethy... more The geometries, relative stabilities, proton af®nities for tautomers of 1, 3,6,10,12,15-hexamethyl-6,7,15,16-tetrahydropyrrolo[3,4-a]pyrrolo [3,4-i][16]annulene (1) and its possible ®xed models (in which proton migration is eliminated) of 1,2,3,6,10, 11,12,15-octamethyl-6,7,15,16-tetrahydropyrrolo[3,4-a]pyrrolo[3,4-i][16]annulene, of 1,2,3,6,8,10,12,15-octamethyl-6,7,8,15,16-pentahydro-2H-pyrrolo[3,4-a]pyrrolo[3,4-i][16]annulene, 1,3,5,7,10,12,14,16-octamethyl-5,6,7,14,15,16-hexahydro-2H-pyrrolo[3,4-a]2H-pyrrolo[3,4-i][16]annulene, molecules were calculated with fully geometry optimization using MNDO, AM1 and PM3 methods in the gas and aqueous phases. A parallelism between the experimental acidity constant values pK a and of the computed acidity constants, pK a was search to clearing the tautomeric forms. q Journal of Molecular Structure (Theochem) 589±590 0166-1280/02/$ -see front matter q
The prototropic, tautomeric, and ionization equilibria of all of the structures of 2-hydroxy-3-(3... more The prototropic, tautomeric, and ionization equilibria of all of the structures of 2-hydroxy-3-(3-oxo-1phenylbutyl)chromen-4-one (warfarin) were studied experimentally and theoretically. The structure elucidation and acidity constant determination along with the tautomeric equilibrium constants were carried out experimentally by a UV-visible spectroscopic method and theoretically investigated at the HF/6-31G(d) and B3LYP/6-31G(d) levels of theory. The obtained K a values were evaluated by structure elucidation and a protonation mechanism. Using the gauge-including atomic-orbital (GIAO) method for calculating 1 H and 13 C nuclear magnetic shielding tensors, the Hartree-Fock (HF) and density functional (DFT) levels of theory were applied to warfarin. Geometry optimizations were also performed on each species, and the absence of negative frequencies verified that all structures were true minima. Theoretical values were compared to the experimental data. Satisfactory agreement between the experimental chemical shifts and the theoretical values of shielding constants (calculated by GIAO/DFT and GIAO/HF methods) was obtained.
Abstract The acid dissociation constants (Ka) of eight novel biologically active benzothiazole Sc... more Abstract The acid dissociation constants (Ka) of eight novel biologically active benzothiazole Schiff bases were determined by UV-vis spectroscopic technique at 25±0.1 C. The calculated acidity constants, pKa values, were evaluated in structure elucidation and ...
The transmission of policy decisions to financial markets is an integral part of the monetary tra... more The transmission of policy decisions to financial markets is an integral part of the monetary transmission mechanism. However, one of the major problems in estimating the effect of monetary policy on asset prices is the simultaneous response of policy actions and the asset prices to each other. To overcome this problem, this study applies the heterokedasticity-based generalized method of moments (GMM) technique suggested by to the Turkish stock market. The results show that an increase in the policy rate leads to a decline in stock prices, especially for the financial sector firms.
The transmission of policy decisions to financial markets is an integral part of the monetary tra... more The transmission of policy decisions to financial markets is an integral part of the monetary transmission mechanism. However, one of the major problems in estimating the effect of monetary policy on asset prices is the simultaneous response of policy actions and the asset prices to each other. suggest a heterokedasticity-based generalized method of moments (GMM) technique to overcome this problem. For emerging markets, there are very few studies using this method. This study applies the heteroskedasticity-based technique to estimate the impact of monetary policy on the Turkish bond, currency and stock markets. This technique also addresses the omitted variables problem. The empirical results verify the findings obtained by event study methods in earlier studies. Firstly, the impact of monetary policy on market interest rates is found to be positive, which diminishes with maturity for maturities longer than 9 months. Secondly, the results suggest that a rise in the policy rate leads to a moderate appreciation of the domestic currency, where the TL/EUR rate is affected more significantly compared to the TL/US dollar rate. Finally, the results show that an increase in the policy rate leads to a decline in stock prices, and monetary policy has the greatest impact on the share prices of the financial sector firms.
Sulfur-containing compounds are present in many important living organisms.(1) One important clas... more Sulfur-containing compounds are present in many important living organisms.(1) One important class of heterocyclic compounds which has the etheric sulfur atom is the five-membered thiazole ring.(2) As they possess several biological properties, thiazole derivatives are the main ...
The geometries, relative stabilities, proton af®nities for tautomers of 1, 3,6,10,12,15-hexamethy... more The geometries, relative stabilities, proton af®nities for tautomers of 1, 3,6,10,12,15-hexamethyl-6,7,15,16-tetrahydropyrrolo[3,4-a]pyrrolo [3,4-i][16]annulene (1) and its possible ®xed models (in which proton migration is eliminated) of 1,2,3,6,10, 11,12,15-octamethyl-6,7,15,16-tetrahydropyrrolo[3,4-a]pyrrolo[3,4-i][16]annulene, of 1,2,3,6,8,10,12,15-octamethyl-6,7,8,15,16-pentahydro-2H-pyrrolo[3,4-a]pyrrolo[3,4-i][16]annulene, 1,3,5,7,10,12,14,16-octamethyl-5,6,7,14,15,16-hexahydro-2H-pyrrolo[3,4-a]2H-pyrrolo[3,4-i][16]annulene, molecules were calculated with fully geometry optimization using MNDO, AM1 and PM3 methods in the gas and aqueous phases. A parallelism between the experimental acidity constant values pK a and of the computed acidity constants, pK a was search to clearing the tautomeric forms. q Journal of Molecular Structure (Theochem) 589±590 0166-1280/02/$ -see front matter q
The prototropic, tautomeric, and ionization equilibria of all of the structures of 2-hydroxy-3-(3... more The prototropic, tautomeric, and ionization equilibria of all of the structures of 2-hydroxy-3-(3-oxo-1phenylbutyl)chromen-4-one (warfarin) were studied experimentally and theoretically. The structure elucidation and acidity constant determination along with the tautomeric equilibrium constants were carried out experimentally by a UV-visible spectroscopic method and theoretically investigated at the HF/6-31G(d) and B3LYP/6-31G(d) levels of theory. The obtained K a values were evaluated by structure elucidation and a protonation mechanism. Using the gauge-including atomic-orbital (GIAO) method for calculating 1 H and 13 C nuclear magnetic shielding tensors, the Hartree-Fock (HF) and density functional (DFT) levels of theory were applied to warfarin. Geometry optimizations were also performed on each species, and the absence of negative frequencies verified that all structures were true minima. Theoretical values were compared to the experimental data. Satisfactory agreement between the experimental chemical shifts and the theoretical values of shielding constants (calculated by GIAO/DFT and GIAO/HF methods) was obtained.
Abstract The acid dissociation constants (Ka) of eight novel biologically active benzothiazole Sc... more Abstract The acid dissociation constants (Ka) of eight novel biologically active benzothiazole Schiff bases were determined by UV-vis spectroscopic technique at 25±0.1 C. The calculated acidity constants, pKa values, were evaluated in structure elucidation and ...
The transmission of policy decisions to financial markets is an integral part of the monetary tra... more The transmission of policy decisions to financial markets is an integral part of the monetary transmission mechanism. However, one of the major problems in estimating the effect of monetary policy on asset prices is the simultaneous response of policy actions and the asset prices to each other. To overcome this problem, this study applies the heterokedasticity-based generalized method of moments (GMM) technique suggested by to the Turkish stock market. The results show that an increase in the policy rate leads to a decline in stock prices, especially for the financial sector firms.
The transmission of policy decisions to financial markets is an integral part of the monetary tra... more The transmission of policy decisions to financial markets is an integral part of the monetary transmission mechanism. However, one of the major problems in estimating the effect of monetary policy on asset prices is the simultaneous response of policy actions and the asset prices to each other. suggest a heterokedasticity-based generalized method of moments (GMM) technique to overcome this problem. For emerging markets, there are very few studies using this method. This study applies the heteroskedasticity-based technique to estimate the impact of monetary policy on the Turkish bond, currency and stock markets. This technique also addresses the omitted variables problem. The empirical results verify the findings obtained by event study methods in earlier studies. Firstly, the impact of monetary policy on market interest rates is found to be positive, which diminishes with maturity for maturities longer than 9 months. Secondly, the results suggest that a rise in the policy rate leads to a moderate appreciation of the domestic currency, where the TL/EUR rate is affected more significantly compared to the TL/US dollar rate. Finally, the results show that an increase in the policy rate leads to a decline in stock prices, and monetary policy has the greatest impact on the share prices of the financial sector firms.
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