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juliana borges

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Pedro Murilo Gonçalves de Freitas

Universidade do Porto

Rafael Luis Pompeia Gioielli

Universidade de São Paulo

Eduardo Morettin

Universidade de São Paulo

UFMG - The Federal University of Minas Gerais

Felipe de Melo Fonte

Getulio Vargas Foundation (Fundação Getulio Vargas)

Rafael L Freire

UFF - Universidade Federal Fluminense

Cezar Migliorin

UFF - Universidade Federal Fluminense

José Maurício Domingues

UERJ - Universidade do Estado do Rio de Janeiro / Rio de Janeiro State University

Annemarie Jordan Gschwend

Universidade Nova de Lisboa

Philippe Oliveira de Almeida

Universidade Federal do Rio de Janeiro (UFRJ)

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Papers by juliana borges

Acolhimento psicológico durante o COVID-19: relato de experiência

Brazilian Journal of Health Review, 2020

Em meados de dezembro de 2019 o mundo se deparou com um surto de pneumonia viral causado pelo nov... more Em meados de dezembro de 2019 o mundo se deparou com um surto de pneumonia viral causado pelo novo coronavírus-SARS-Cov-2 (Severe Acute Respiratory Syndrome Coronavirus) causador da doença Covid-19 a qual foi o primeiro reportada na China. Com o decorrer do avanço abrupto de disseminação e consequentemente o elevado número mundialmente, em janeiro, a Organização Mundial da Saúde (OMS) declarou Emergência de Saúde Pública de Interesse Internacional, diante de tal gravidade, em março foi aprovada a Lei da Quarentena, com medidas como: isolamento social, quarentena, notificação obrigatória entre outras. Objetivo: Relatar o impacto da pandemia Covid-19 em colaboradores, professores e alunos de um Centro Universitário FAMETRO-CEUNI localizado em Manaus-Amazonas por meio da estratégia de acolhimento psicológico. Método: Trata-se de um relato de experiência do tipo descritivo, baseado na experiência de finalistas do curso de psicologia frente aos efeitos observados na população acadêmica diante do novo coronavírus. Discussão: Foram visualizados pontos chaves de repercussão entre os acolhidos, sendo eles: processo abalado com autorregulação emocional, estresse, dificuldade no planejamento e execução de atividades, delimitação e organicidade do tempo, ansiedade e angustia, sintomas depressivos e, afetos negativos. Dessa forma, observou-se pela equipe que haviam sintomas semelhantes entre os acolhidos, demonstrando que aspectos psicológicos são recorrentes no contexto da pandemia do Covid-19. Considerações finais: profissionais e acadêmicos sofrem pressões psicológicas similares considerando o contexto de adoecimento e incerteza ante à pandemia, valendo-se fundamentalmente na prática assertiva do acolhimento e orientação breve focal.

AB1198 Clinical Profile of Hand Osteoarthritis in a Low Income Population

Annals of the Rheumatic Diseases, May 30, 2023

Backgroundhand osteoarthritis (HOA) is a highly prevalent disease that may be impacted by social ... more Backgroundhand osteoarthritis (HOA) is a highly prevalent disease that may be impacted by social inequalities. However, there are few studies on HOA from underdeveloped regions.Objectivesto present clinical characteristics of a HOA cohort from a low-income population.Methodsclinical data and serum from 70 patients with a diagnosis of HOA fulfilling ACR criteria seen between March 2020 and December 2022 in Fortaleza/Brazil registering hypertension, diabetes, obesity (BMI&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;30 kg/m²), and concurrent diagnosis of knee or spine OA and “bunions”; pain (VAS, visual analogue scale), X-ray (Kellgren-Lawrence) and ultrasonography (US) [synovitis and power-doppler (PD) sign] of the most affected joint of the hand were recorded, as well as grip and pinch strength (KgF), Cochin hand functional scale (CHFS), FIHOA, and SF-12 scores. Social data included income, occupation [white (WCJ)vs.blue (BCJ) colar jobs], education level [&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;/≤ 8 school-years (SY)].Results70 patients were included, comprising 66(94%) women, mean age 60.3±10.3 with 12(17.1%) below 50 years-old; median disease duration was 72(range 30-120) months. Pain on movement (VAS) was 7.4±1.9, grip strength 14.5±6.4, pinch strength 1.7±1, CHFS 21±14.8, FIHOA 10.3±6.2, and SF-12 32.1±3; 54(77.1%) had KL≥3. All but 2 out of 61 evaluated joints had synovitis at US with only 4(6.7%) displaying positive PD signal; 27(38.5%) had isolated HOA; 9(12.8%), 8(11.4%), and 5(7.1%) had concurrent spine or knee OA or bunions, respectively and 22(31.4%) had ≥2 sites other than HOA; 31(44.2%), 16(22.8%), and 7(10%) had hypertension, obesity and diabetes as comorbidities, respectively; 38(54.2%) declared &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;900 US$ monthly family earnings, 8(11.4%) had &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;8SY and 27(38.5%) had occupations classified as BCJ. Mean pain was similar regardless of occupation, literacy (SY) or monthly family income. Although pain in BCJ group (7.9±1.7) was higher than in WCJ group (7.1±2) it did not reach statistical significance (p=0.0576); CHFS, FIHOA and SF-12 scores were similar regardless of occupation, SY or income; total mean CRP was 0.41±0.64 mg/dL; mean CRP in those with concurrent knee OA (0.38±0.25 mg/dL) had a trend to be higher than in isolated HOA patients 0.24±0.1 mg/dL (p=0.0547).ConclusionOur results suggest that income and literacy did not influence disease severity in HOA in our low income cohort.REFERENCES:NIL.Acknowledgements:NIL.Disclosure of InterestsNone Declared.

Síndrome de Down: bases genéticas e principais alterações

Brazilian Journal of Development, Aug 9, 2022

A Síndrome de Down foi relatada inicialmente pelo médico John Langdon em meados de 1866 mediante ... more A Síndrome de Down foi relatada inicialmente pelo médico John Langdon em meados de 1866 mediante semelhanças físicas observadas em crianças que apresentavam atraso mental no qual eram designadas como situação de “mongolismo” para que fosse possível a definição do conjunto de manifestações que estavam sendo observadas. Compreende-se que o entendimento das bases fisiopatológicas da SD é de suma importância tendo em vista que tal conhecimento será capaz de proporcionar novas terapêuticas farmacológicas e não farmacológicas específicas para os indivíduos com a SD. Por certo, associado a fatores genéticos, os fatores epigenéticos, como interações celulares, também são responsáveis pela estruturação do fenótipo de pacientes com SD permitindo, portanto, a verificação de diferentes alterações como complicações congênitas e também acometimento audível, visual e cardíaco.

Síntese e Aplicação De Rede Metalorgânica (MOF-808) Para Adsorção De CO2 Em Pressões De Até 35 Bar

Anais do Congresso Brasileiro de Sistemas Particulados, 2022

Effects of physical exercise in the perception of life satisfaction and immunological function in HIV- infected patients: Non-randomized clinical trial Efeito do exercício físico na percepção de satisfação de vida e função imunológica em pacientes infectados pelo HIV: Ensaio clínico não randomizado

Background: There is a lack of research about the relationship between exercise and the psycholog... more Background: There is a lack of research about the relationship between exercise and the psychological well-being of HIV-infected (Human Immunodeficiency Virus) patients. Objective: The objective of this study was to investigate the influence of a physical training program on life satisfaction and on the immunological function in HIV-patients. Methods: A total of 29 HIV-seropositive patients [age: 45±2 yrs; Body Mass Index (BMI): 22.8±1.0 kg/m 2 ; TCD4: 20.5±2.0%] were allocated to the control (CG, n=10) and to the experimental groups (EG, n=19). The EG participated in an exercise program combining aerobic, strength, and flexibility exercises for a period of 12 weeks [3 times/week of 30 min of aerobic exercise (workload corresponding to 150 bpm-PWC150); 50 min of strength exercises (3 sets of 12 repetitions in 5 exercises at 60-80% 12 RM); and 10 min of flexibility exercises (2 sets of 30 seconds at maximal range of motion of 8 exercises)]. The immunological function was assessed by flow citometry [absolute and relative TCD4 cells counting] and the life satisfaction was assessed by the Life Satisfaction Index (LSI). Results: The analysis of variance (ANOVA) showed no significant differences for relative and absolute CD4 T counts for both groups, however, a slight enhancement trend in the EG [16%, p=0.19] was observed. There was a significant improvement of LSI [approximately 15%; P<0.05] in EG, but not for CG. Conclusion: A physical activity program of moderate intensity improved life satisfaction perception in HIV-infected patients with no immunological function impairment. Article registered in the Australian New Zealand Clinical Trials Registry under the number ACTRN12610000683033.

Teoria e métodos do processo de inclusão educacional : visibilidade, materialidade, fragmentos e multiplicidade

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Effect of cardiac rehabilitation on the nociceptive threshold increased of hypertensive subjects

Fisioterapia Brasil, Jun 27, 2022

Effect of cardiac rehabilitation on the nociceptive threshold increased of hypertensive subjects ... more

The Effects of Acute Aerobic Exercise on Blood Pressure, Arterial Function, and Heart Rate Variability in Men Living With HIV

Frontiers in Physiology

PurposeThis study aims to investigate the effects of acute cycling on blood pressure (BP), arteri... more PurposeThis study aims to investigate the effects of acute cycling on blood pressure (BP), arterial function, and heart rate variability (HRV) in men living with HIV (MLHIV) using combined antiretroviral therapy (cART).MethodsTwelve MLHIV (48.7 ± 9.2 years; 25.2 ± 2.8 kg m–2) and 13 healthy controls (41.2 ± 9.9 years; 26.3 ± 2.9 kg m–2) performed a cycling bout (ES) (intensity: 50% oxygen uptake reserve; duration: time to achieve 150 kcal—MLHIV: 24.1 ± 5.5 vs. controls: 23.1 ± 3.0 min; p = 0.45), and a 20-min non-exercise session (NES).ResultsAt rest (p < 0.05), MLHIV presented higher brachial systolic/diastolic BP (SBP/DBP: 123.2 ± 14.2/76.8 ± 6.3 vs. 114.3 ± 5.1/71.6 ± 2.6 mmHg) and central BP (cSBP/cDBP: 108.3 ± 9.3/76.5 ± 6.5 vs. 101.6 ± 4.9/71.3 ± 4.4 mmHg) vs. controls but lower absolute maximal oxygen uptake (2.1 ± 0.5 vs. 2.5 ± 0.3 L min–1) and HRV indices reflecting overall/vagal modulation (SDNN: 24.8 ± 7.1 vs. 42.9 ± 21.3 ms; rMSSD: 20.5 ± 8.5 vs. 38.1 ± 22.8 ms; pNN50...

Aquatic Exercise on Brain Activity in Type 2 Diabetic: Randomized Clinical Trial

International Journal of Environmental Research and Public Health

Background: A water-based physical exercise program is extremely important for the rehabilitation... more Background: A water-based physical exercise program is extremely important for the rehabilitation of type 2 diabetes. Little is known about its action on cerebral electrical activity. Objective: To evaluate the effect of a water-based physical exercise protocol on electroencephalographic activity, blood glucose levels, and functional capacity, as well as their correlation, in type 2 diabetics. Methods: Study design: Randomized Clinical Trial. Forty volunteers were randomized into two groups: control (n = 20) and study (n = 20). A water-based physical exercise program comprising 50 min sessions was conducted three times a week for five weeks. Assessments were performed at the pre- and post-intervention and follow-up phases. The qualitative data were compared using the Mann–Whitney test and Chi-Square. Quantitative data were compared using the Kruskal–Wallis, Independent t, and ANOVA mixed tests. The Spearman correlation coefficient was used to correlate the data. Results: The data we...

Cnidaria Medusozoa (Hydrozoa, Scyphozoa e Cubozoa) do projeto bentos marinhos - BIOTA/FAPESP

Caderno de resumos e palestras, 2003

Atuação do Sebrae nos Ambientes de Inovação: horizonte de atuação a partir de 2019

Cadernos de Prospecção, 2021

O Serviço Brasileiro de Apoio às Micro e Pequenas Empresas (SEBRAE) trabalha há quase duas década... more O Serviço Brasileiro de Apoio às Micro e Pequenas Empresas (SEBRAE) trabalha há quase duas décadas junto às incubadoras por meio de convênios de cooperação com a Associação Nacional de Entidades Promotoras de Empreendimentos Inovadores (ANPROTEC). Para dinamizar essa atuação em nível nacional, contemplando os Sebrae localizados nos 26 Estados e no Distrito Federal, criou-se, ao final de 2018, uma estratégia nacional para unificar e direcionar os esforços de conexão. O conteúdo deste artigo é uma simplificação da estratégia construída pela equipe para potencializar os espaços de inovação.

Terapia assistida por gatos com idosos institucionalizados: Revisão bibliográfica

Tópicos em Ciência Animal – Volume 1, 2021

Capítulo 12: Ocorrências de desvios angulares do carpo em potros da raça quarto de milha em um ha... more

Análise da Fadiga Relatada e das Forças Musculares Respiratória e Periférica em indivíduos com Câncer em Tratamento

Revista Brasileira de Cancerologia, 2020

Introdução: Nos últimos anos, o tratamento do câncer evoluiu, possibilitando uma maior sobrevida ... more Introdução: Nos últimos anos, o tratamento do câncer evoluiu, possibilitando uma maior sobrevida ao paciente, porém os efeitos colaterais, como a diminuição da imunidade e a fadiga, influenciam o sistema respiratório e muscular. Objetivo: Analisar a fadiga e as forças musculares respiratória e periférica em voluntários com câncer em tratamento e em indivíduos saudáveis. Método: Trata-se de um estudo analítico, observacional, transversal e controlado. Os indivíduos foram distribuídos em dois grupos: um grupo de câncer em quimioterapia e/ou em radioterapia (GCA: n=98; homens=35,72%; mulheres=64,28%; idade=58,13±13,26 anos; índice de massa corporal (IMC=26,23±4,04 kg/m2; tempo de diagnóstico de câncer=27,54±9,61 meses) e um grupo controle (GC: n=86; homens=30,23%; mulheres=69,77; idade=59,24±12,87 anos; IMC=26,76±4,04 kg/m2). Para todos os indivíduos, a fadiga relatada foi avaliada, usando-se a subescala de fadiga do questionário The Functional Assessment of Cancer Therapy-Fatigue (FAC...

Physical activity among women of low socioeconomic status living with HIV in two major cities of Brazil and Mozambique: A cross-sectional comparative study

Clinics, 2020

Physical activity (PA) may reduce cardiovascular risk and preserve functional capacity of people ... more Physical activity (PA) may reduce cardiovascular risk and preserve functional capacity of people living with human immunodeficiency virus (HIV). However, only limited research objectively measured PA in patients with low socioeconomic status (SES) in low-income countries, particularly in South America and sub-Saharan Africa. This study compared the PA assessed by accelerometers in women of low SES living with HIV under common antiretroviral therapy (cART) from two major cities in Brazil (Rio de Janeiro, n=33; 40.1±6.1 years) and Mozambique (Maputo, n=50; 38.8 ± 8.7 years). METHODS: Eligible women wore triaxial accelerometers during seven consecutive days, to estimate their habitual PA and daily energy expenditure. RESULTS: The proportion of participants with overweight/obesity was greater in Rio than Maputo (57% vs. 30%; p=0.021), as well as those classified as sedentary based on steps/day (45% vs. 22%; p=0.02). Sedentary time was prevalent (Median ± IQD: Rio-1236 ± 142 vs. Maputo-1192 ± 135 min/day; p=0.15). Time spent in PA was short, but Brazilians exhibited lower amount of light (111 ± 56 vs. 145 ± 51 min/day; po0.001) and moderate-tovigorous PA (88±3 vs. 64±36 min/day; p=0.001) vs. Mozambicans. The proportion of patients performing 60 min/day of moderate-to-vigorous PA were 58% (Rio) and 82% (Maputo), respectively. Despite of this, estimated daily energy expenditure was equivalent in both groups (1976 ± 579 vs. 1933 ± 492 kcal; p=0.731). CONCLUSIONS: Women with low SES living with HIV in Maputo were more active vs. patients from Rio de Janeiro. Albeit sedentary behavior was prevalent, the proportion of patients complying with the minimum recommended PA for health was higher than values usually reported in developed countries.

Separacao de variaveis para o hamiltoniano de um poco quantico parabolico sujeito a campo magnetico inclinado

The effects of auricular acupuncture on vascular parameters on the risk factors for diabetic foot: A randomized clinical trial

Complementary Therapies in Clinical Practice, 2021

AIMS AND OBJECTIVES To evaluate the effects of auricular acupuncture on vascular parameters on th... more AIMS AND OBJECTIVES To evaluate the effects of auricular acupuncture on vascular parameters on the risk factors for Diabetic Foot. METHODS Randomized and masked clinical trial. The sample was composed of 44 individuals with type 2 Diabetes Mellitus and they were randomly assigned to two groups: intervention (n = 22), which received five sessions of auricular acupuncture, and control (n = 22), which did not receive the therapy. Three evaluations were performed: before the intervention; one day after the last acupuncture session and 15 days after the second evaluation. For this, the subject's characterization instrument, the Ankle-Brachial Index measurement, and thermography were used. For data analysis, Mann-Whitney, Wilcoxon, Wilcoxon signed-rank, Fisher's Exact and Chi-Square tests were used. RESULTS Auriculotherapy provided results in the Ankle-Brachial Index Test, as well as in thermography, which showed significant temperature improvement. CONCLUSIONS The technique proved to be efficient in improving circulatory conditions and plantar temperature.

Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae

Molecular and Biochemical Parasitology, 2020

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Compreendendo a autoimagem e a autoestima em adolescentes com câncer: Uma revisão integrativa

Revista Científica Multidisciplinar Núcleo do Conhecimento, 2020

O câncer é considerado uma doença degenerativa, consequente do acúmulo de lesões nas células que ... more O câncer é considerado uma doença degenerativa, consequente do acúmulo de lesões nas células que induz a reprodução desordenada das mesmas, dando origem aos tumores. Os efeitos colaterais do tratamento do câncer na adolescência podem comprometer a autoimagem e a autoestima e, repercutir na relação dos adolescentes consigo mesmo e com o outro. O objetivo desta revisão foi observar na literatura, os reflexos da doença na autoimagem e autoestima dos adolescentes. Os resultados apontaram que a autoimagem e a autoestima em adolescentes são afetadas com a manifestação da doença e seu tratamento. Portanto, considera-se relevante disponibilizar nos hospitais um espaço para escuta dos adolescentes, no intuito de criar possibilidades para minimizar o sofrimento e promover bem-estar psíquico.

Berries and leukemia: a systematic review of experimental studies and the in vitro effect of ellagic acid on chronic myeloid leukemia cells

Brazilian Journal of Health Review, 2020

Berries and leukemia: a systematic review of experimental studies and the in vitro effect of ella... more Berries and leukemia: a systematic review of experimental studies and the in vitro effect of ellagic acid on chronic myeloid leukemia cells Frutas vermelhas e leucemia: uma revisão sistemática de estudos experimentais e o efeito in vitro do ácido elágico sobre células de leucemia mieloide crônica

Effects of short-term high-intensity interval and continuous exercise training on body composition and cardiac function in obese sarcopenic rats

Life Sciences, 2020

We investigated the effects of high-intensity interval and continuous short-term exercise on body... more We investigated the effects of high-intensity interval and continuous short-term exercise on body composition and cardiac function after myocardial ischemia-reperfusion injury (IRI) in obese rats. Methods: Rats fed with a standard chow diet (SC) or high-fat diet (HFD) for 20 weeks underwent systolic blood pressure (SBP), glycemia and dual-energy X-ray absorptiometry analyses. Then, animals fed with HFD were subdivided into three groups: sedentary (HFD-SED); moderate-intensity continuous training (HFD-MICT); and high-intensity interval training (HFD-HIIT). Exercised groups underwent four isocaloric aerobic exercise sessions, in which HFD-MICT maintained the intensity continuously and HFD-HIIT alternated it. After exercise sessions, all groups underwent global IRI and myocardial infarct size (IS) was determined histologically. Fat and muscle mass were weighted, and protein levels involved in muscle metabolism were assessed in skeletal muscle. Results: HFD-fed versus SC-fed rats reduced lean body mass by 31% (P < 0.001), while SBP, glycemia and body fat percentage were increased by 10% (P = 0.04), 30% (P = 0.006) and 54% (P < 0.001); respectively. HFDinduced muscle atrophy was restored in exercised groups, as only HFD-SED presented lower gastrocnemius (32%; P = 0.001) and quadriceps mass (62%; P < 0.001) than SC. PGC1-α expression was 2.7-fold higher in HFD-HIIT versus HFD-SED (P = 0.04), whereas HFD-HIIT and HFD-MICT exhibited 1.7-fold increase in p-mTOR Ser2481 levels compared to HFD-SED (P = 0.04). Although no difference was detected among groups for IS (P = 0.30), only HFD-HIIT preserved left-ventricle developed pressure after IRI (+0.7 mmHg; P = 0.9). Significance: Short-term exercise, continuous or HIIT, restored HFD-induced muscle atrophy and increased mTOR expression, but only HIIT maintained myocardial contractility following IRI in obese animals.

Acolhimento psicológico durante o COVID-19: relato de experiência

Brazilian Journal of Health Review, 2020

Em meados de dezembro de 2019 o mundo se deparou com um surto de pneumonia viral causado pelo nov... more Em meados de dezembro de 2019 o mundo se deparou com um surto de pneumonia viral causado pelo novo coronavírus-SARS-Cov-2 (Severe Acute Respiratory Syndrome Coronavirus) causador da doença Covid-19 a qual foi o primeiro reportada na China. Com o decorrer do avanço abrupto de disseminação e consequentemente o elevado número mundialmente, em janeiro, a Organização Mundial da Saúde (OMS) declarou Emergência de Saúde Pública de Interesse Internacional, diante de tal gravidade, em março foi aprovada a Lei da Quarentena, com medidas como: isolamento social, quarentena, notificação obrigatória entre outras. Objetivo: Relatar o impacto da pandemia Covid-19 em colaboradores, professores e alunos de um Centro Universitário FAMETRO-CEUNI localizado em Manaus-Amazonas por meio da estratégia de acolhimento psicológico. Método: Trata-se de um relato de experiência do tipo descritivo, baseado na experiência de finalistas do curso de psicologia frente aos efeitos observados na população acadêmica diante do novo coronavírus. Discussão: Foram visualizados pontos chaves de repercussão entre os acolhidos, sendo eles: processo abalado com autorregulação emocional, estresse, dificuldade no planejamento e execução de atividades, delimitação e organicidade do tempo, ansiedade e angustia, sintomas depressivos e, afetos negativos. Dessa forma, observou-se pela equipe que haviam sintomas semelhantes entre os acolhidos, demonstrando que aspectos psicológicos são recorrentes no contexto da pandemia do Covid-19. Considerações finais: profissionais e acadêmicos sofrem pressões psicológicas similares considerando o contexto de adoecimento e incerteza ante à pandemia, valendo-se fundamentalmente na prática assertiva do acolhimento e orientação breve focal.

AB1198 Clinical Profile of Hand Osteoarthritis in a Low Income Population

Annals of the Rheumatic Diseases, May 30, 2023

Backgroundhand osteoarthritis (HOA) is a highly prevalent disease that may be impacted by social ... more Backgroundhand osteoarthritis (HOA) is a highly prevalent disease that may be impacted by social inequalities. However, there are few studies on HOA from underdeveloped regions.Objectivesto present clinical characteristics of a HOA cohort from a low-income population.Methodsclinical data and serum from 70 patients with a diagnosis of HOA fulfilling ACR criteria seen between March 2020 and December 2022 in Fortaleza/Brazil registering hypertension, diabetes, obesity (BMI&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;30 kg/m²), and concurrent diagnosis of knee or spine OA and “bunions”; pain (VAS, visual analogue scale), X-ray (Kellgren-Lawrence) and ultrasonography (US) [synovitis and power-doppler (PD) sign] of the most affected joint of the hand were recorded, as well as grip and pinch strength (KgF), Cochin hand functional scale (CHFS), FIHOA, and SF-12 scores. Social data included income, occupation [white (WCJ)vs.blue (BCJ) colar jobs], education level [&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;/≤ 8 school-years (SY)].Results70 patients were included, comprising 66(94%) women, mean age 60.3±10.3 with 12(17.1%) below 50 years-old; median disease duration was 72(range 30-120) months. Pain on movement (VAS) was 7.4±1.9, grip strength 14.5±6.4, pinch strength 1.7±1, CHFS 21±14.8, FIHOA 10.3±6.2, and SF-12 32.1±3; 54(77.1%) had KL≥3. All but 2 out of 61 evaluated joints had synovitis at US with only 4(6.7%) displaying positive PD signal; 27(38.5%) had isolated HOA; 9(12.8%), 8(11.4%), and 5(7.1%) had concurrent spine or knee OA or bunions, respectively and 22(31.4%) had ≥2 sites other than HOA; 31(44.2%), 16(22.8%), and 7(10%) had hypertension, obesity and diabetes as comorbidities, respectively; 38(54.2%) declared &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;900 US$ monthly family earnings, 8(11.4%) had &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;8SY and 27(38.5%) had occupations classified as BCJ. Mean pain was similar regardless of occupation, literacy (SY) or monthly family income. Although pain in BCJ group (7.9±1.7) was higher than in WCJ group (7.1±2) it did not reach statistical significance (p=0.0576); CHFS, FIHOA and SF-12 scores were similar regardless of occupation, SY or income; total mean CRP was 0.41±0.64 mg/dL; mean CRP in those with concurrent knee OA (0.38±0.25 mg/dL) had a trend to be higher than in isolated HOA patients 0.24±0.1 mg/dL (p=0.0547).ConclusionOur results suggest that income and literacy did not influence disease severity in HOA in our low income cohort.REFERENCES:NIL.Acknowledgements:NIL.Disclosure of InterestsNone Declared.

Síndrome de Down: bases genéticas e principais alterações

Brazilian Journal of Development, Aug 9, 2022

A Síndrome de Down foi relatada inicialmente pelo médico John Langdon em meados de 1866 mediante ... more A Síndrome de Down foi relatada inicialmente pelo médico John Langdon em meados de 1866 mediante semelhanças físicas observadas em crianças que apresentavam atraso mental no qual eram designadas como situação de “mongolismo” para que fosse possível a definição do conjunto de manifestações que estavam sendo observadas. Compreende-se que o entendimento das bases fisiopatológicas da SD é de suma importância tendo em vista que tal conhecimento será capaz de proporcionar novas terapêuticas farmacológicas e não farmacológicas específicas para os indivíduos com a SD. Por certo, associado a fatores genéticos, os fatores epigenéticos, como interações celulares, também são responsáveis pela estruturação do fenótipo de pacientes com SD permitindo, portanto, a verificação de diferentes alterações como complicações congênitas e também acometimento audível, visual e cardíaco.

Síntese e Aplicação De Rede Metalorgânica (MOF-808) Para Adsorção De CO2 Em Pressões De Até 35 Bar

Anais do Congresso Brasileiro de Sistemas Particulados, 2022

Effects of physical exercise in the perception of life satisfaction and immunological function in HIV- infected patients: Non-randomized clinical trial Efeito do exercício físico na percepção de satisfação de vida e função imunológica em pacientes infectados pelo HIV: Ensaio clínico não randomizado

Background: There is a lack of research about the relationship between exercise and the psycholog... more Background: There is a lack of research about the relationship between exercise and the psychological well-being of HIV-infected (Human Immunodeficiency Virus) patients. Objective: The objective of this study was to investigate the influence of a physical training program on life satisfaction and on the immunological function in HIV-patients. Methods: A total of 29 HIV-seropositive patients [age: 45±2 yrs; Body Mass Index (BMI): 22.8±1.0 kg/m 2 ; TCD4: 20.5±2.0%] were allocated to the control (CG, n=10) and to the experimental groups (EG, n=19). The EG participated in an exercise program combining aerobic, strength, and flexibility exercises for a period of 12 weeks [3 times/week of 30 min of aerobic exercise (workload corresponding to 150 bpm-PWC150); 50 min of strength exercises (3 sets of 12 repetitions in 5 exercises at 60-80% 12 RM); and 10 min of flexibility exercises (2 sets of 30 seconds at maximal range of motion of 8 exercises)]. The immunological function was assessed by flow citometry [absolute and relative TCD4 cells counting] and the life satisfaction was assessed by the Life Satisfaction Index (LSI). Results: The analysis of variance (ANOVA) showed no significant differences for relative and absolute CD4 T counts for both groups, however, a slight enhancement trend in the EG [16%, p=0.19] was observed. There was a significant improvement of LSI [approximately 15%; P<0.05] in EG, but not for CG. Conclusion: A physical activity program of moderate intensity improved life satisfaction perception in HIV-infected patients with no immunological function impairment. Article registered in the Australian New Zealand Clinical Trials Registry under the number ACTRN12610000683033.

Teoria e métodos do processo de inclusão educacional : visibilidade, materialidade, fragmentos e multiplicidade

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Effect of cardiac rehabilitation on the nociceptive threshold increased of hypertensive subjects

Fisioterapia Brasil, Jun 27, 2022

Effect of cardiac rehabilitation on the nociceptive threshold increased of hypertensive subjects ... more

The Effects of Acute Aerobic Exercise on Blood Pressure, Arterial Function, and Heart Rate Variability in Men Living With HIV

Frontiers in Physiology

PurposeThis study aims to investigate the effects of acute cycling on blood pressure (BP), arteri... more PurposeThis study aims to investigate the effects of acute cycling on blood pressure (BP), arterial function, and heart rate variability (HRV) in men living with HIV (MLHIV) using combined antiretroviral therapy (cART).MethodsTwelve MLHIV (48.7 ± 9.2 years; 25.2 ± 2.8 kg m–2) and 13 healthy controls (41.2 ± 9.9 years; 26.3 ± 2.9 kg m–2) performed a cycling bout (ES) (intensity: 50% oxygen uptake reserve; duration: time to achieve 150 kcal—MLHIV: 24.1 ± 5.5 vs. controls: 23.1 ± 3.0 min; p = 0.45), and a 20-min non-exercise session (NES).ResultsAt rest (p < 0.05), MLHIV presented higher brachial systolic/diastolic BP (SBP/DBP: 123.2 ± 14.2/76.8 ± 6.3 vs. 114.3 ± 5.1/71.6 ± 2.6 mmHg) and central BP (cSBP/cDBP: 108.3 ± 9.3/76.5 ± 6.5 vs. 101.6 ± 4.9/71.3 ± 4.4 mmHg) vs. controls but lower absolute maximal oxygen uptake (2.1 ± 0.5 vs. 2.5 ± 0.3 L min–1) and HRV indices reflecting overall/vagal modulation (SDNN: 24.8 ± 7.1 vs. 42.9 ± 21.3 ms; rMSSD: 20.5 ± 8.5 vs. 38.1 ± 22.8 ms; pNN50...

Aquatic Exercise on Brain Activity in Type 2 Diabetic: Randomized Clinical Trial

International Journal of Environmental Research and Public Health

Background: A water-based physical exercise program is extremely important for the rehabilitation... more Background: A water-based physical exercise program is extremely important for the rehabilitation of type 2 diabetes. Little is known about its action on cerebral electrical activity. Objective: To evaluate the effect of a water-based physical exercise protocol on electroencephalographic activity, blood glucose levels, and functional capacity, as well as their correlation, in type 2 diabetics. Methods: Study design: Randomized Clinical Trial. Forty volunteers were randomized into two groups: control (n = 20) and study (n = 20). A water-based physical exercise program comprising 50 min sessions was conducted three times a week for five weeks. Assessments were performed at the pre- and post-intervention and follow-up phases. The qualitative data were compared using the Mann–Whitney test and Chi-Square. Quantitative data were compared using the Kruskal–Wallis, Independent t, and ANOVA mixed tests. The Spearman correlation coefficient was used to correlate the data. Results: The data we...

Cnidaria Medusozoa (Hydrozoa, Scyphozoa e Cubozoa) do projeto bentos marinhos - BIOTA/FAPESP

Caderno de resumos e palestras, 2003

Atuação do Sebrae nos Ambientes de Inovação: horizonte de atuação a partir de 2019

Cadernos de Prospecção, 2021

O Serviço Brasileiro de Apoio às Micro e Pequenas Empresas (SEBRAE) trabalha há quase duas década... more O Serviço Brasileiro de Apoio às Micro e Pequenas Empresas (SEBRAE) trabalha há quase duas décadas junto às incubadoras por meio de convênios de cooperação com a Associação Nacional de Entidades Promotoras de Empreendimentos Inovadores (ANPROTEC). Para dinamizar essa atuação em nível nacional, contemplando os Sebrae localizados nos 26 Estados e no Distrito Federal, criou-se, ao final de 2018, uma estratégia nacional para unificar e direcionar os esforços de conexão. O conteúdo deste artigo é uma simplificação da estratégia construída pela equipe para potencializar os espaços de inovação.

Terapia assistida por gatos com idosos institucionalizados: Revisão bibliográfica

Tópicos em Ciência Animal – Volume 1, 2021

Capítulo 12: Ocorrências de desvios angulares do carpo em potros da raça quarto de milha em um ha... more

Análise da Fadiga Relatada e das Forças Musculares Respiratória e Periférica em indivíduos com Câncer em Tratamento

Revista Brasileira de Cancerologia, 2020

Introdução: Nos últimos anos, o tratamento do câncer evoluiu, possibilitando uma maior sobrevida ... more Introdução: Nos últimos anos, o tratamento do câncer evoluiu, possibilitando uma maior sobrevida ao paciente, porém os efeitos colaterais, como a diminuição da imunidade e a fadiga, influenciam o sistema respiratório e muscular. Objetivo: Analisar a fadiga e as forças musculares respiratória e periférica em voluntários com câncer em tratamento e em indivíduos saudáveis. Método: Trata-se de um estudo analítico, observacional, transversal e controlado. Os indivíduos foram distribuídos em dois grupos: um grupo de câncer em quimioterapia e/ou em radioterapia (GCA: n=98; homens=35,72%; mulheres=64,28%; idade=58,13±13,26 anos; índice de massa corporal (IMC=26,23±4,04 kg/m2; tempo de diagnóstico de câncer=27,54±9,61 meses) e um grupo controle (GC: n=86; homens=30,23%; mulheres=69,77; idade=59,24±12,87 anos; IMC=26,76±4,04 kg/m2). Para todos os indivíduos, a fadiga relatada foi avaliada, usando-se a subescala de fadiga do questionário The Functional Assessment of Cancer Therapy-Fatigue (FAC...

Physical activity among women of low socioeconomic status living with HIV in two major cities of Brazil and Mozambique: A cross-sectional comparative study

Clinics, 2020

Physical activity (PA) may reduce cardiovascular risk and preserve functional capacity of people ... more Physical activity (PA) may reduce cardiovascular risk and preserve functional capacity of people living with human immunodeficiency virus (HIV). However, only limited research objectively measured PA in patients with low socioeconomic status (SES) in low-income countries, particularly in South America and sub-Saharan Africa. This study compared the PA assessed by accelerometers in women of low SES living with HIV under common antiretroviral therapy (cART) from two major cities in Brazil (Rio de Janeiro, n=33; 40.1±6.1 years) and Mozambique (Maputo, n=50; 38.8 ± 8.7 years). METHODS: Eligible women wore triaxial accelerometers during seven consecutive days, to estimate their habitual PA and daily energy expenditure. RESULTS: The proportion of participants with overweight/obesity was greater in Rio than Maputo (57% vs. 30%; p=0.021), as well as those classified as sedentary based on steps/day (45% vs. 22%; p=0.02). Sedentary time was prevalent (Median ± IQD: Rio-1236 ± 142 vs. Maputo-1192 ± 135 min/day; p=0.15). Time spent in PA was short, but Brazilians exhibited lower amount of light (111 ± 56 vs. 145 ± 51 min/day; po0.001) and moderate-tovigorous PA (88±3 vs. 64±36 min/day; p=0.001) vs. Mozambicans. The proportion of patients performing 60 min/day of moderate-to-vigorous PA were 58% (Rio) and 82% (Maputo), respectively. Despite of this, estimated daily energy expenditure was equivalent in both groups (1976 ± 579 vs. 1933 ± 492 kcal; p=0.731). CONCLUSIONS: Women with low SES living with HIV in Maputo were more active vs. patients from Rio de Janeiro. Albeit sedentary behavior was prevalent, the proportion of patients complying with the minimum recommended PA for health was higher than values usually reported in developed countries.

Separacao de variaveis para o hamiltoniano de um poco quantico parabolico sujeito a campo magnetico inclinado

The effects of auricular acupuncture on vascular parameters on the risk factors for diabetic foot: A randomized clinical trial

Complementary Therapies in Clinical Practice, 2021

AIMS AND OBJECTIVES To evaluate the effects of auricular acupuncture on vascular parameters on th... more AIMS AND OBJECTIVES To evaluate the effects of auricular acupuncture on vascular parameters on the risk factors for Diabetic Foot. METHODS Randomized and masked clinical trial. The sample was composed of 44 individuals with type 2 Diabetes Mellitus and they were randomly assigned to two groups: intervention (n = 22), which received five sessions of auricular acupuncture, and control (n = 22), which did not receive the therapy. Three evaluations were performed: before the intervention; one day after the last acupuncture session and 15 days after the second evaluation. For this, the subject's characterization instrument, the Ankle-Brachial Index measurement, and thermography were used. For data analysis, Mann-Whitney, Wilcoxon, Wilcoxon signed-rank, Fisher's Exact and Chi-Square tests were used. RESULTS Auriculotherapy provided results in the Ankle-Brachial Index Test, as well as in thermography, which showed significant temperature improvement. CONCLUSIONS The technique proved to be efficient in improving circulatory conditions and plantar temperature.

Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae

Molecular and Biochemical Parasitology, 2020

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Compreendendo a autoimagem e a autoestima em adolescentes com câncer: Uma revisão integrativa

Revista Científica Multidisciplinar Núcleo do Conhecimento, 2020

O câncer é considerado uma doença degenerativa, consequente do acúmulo de lesões nas células que ... more O câncer é considerado uma doença degenerativa, consequente do acúmulo de lesões nas células que induz a reprodução desordenada das mesmas, dando origem aos tumores. Os efeitos colaterais do tratamento do câncer na adolescência podem comprometer a autoimagem e a autoestima e, repercutir na relação dos adolescentes consigo mesmo e com o outro. O objetivo desta revisão foi observar na literatura, os reflexos da doença na autoimagem e autoestima dos adolescentes. Os resultados apontaram que a autoimagem e a autoestima em adolescentes são afetadas com a manifestação da doença e seu tratamento. Portanto, considera-se relevante disponibilizar nos hospitais um espaço para escuta dos adolescentes, no intuito de criar possibilidades para minimizar o sofrimento e promover bem-estar psíquico.

Berries and leukemia: a systematic review of experimental studies and the in vitro effect of ellagic acid on chronic myeloid leukemia cells

Brazilian Journal of Health Review, 2020

Berries and leukemia: a systematic review of experimental studies and the in vitro effect of ella... more Berries and leukemia: a systematic review of experimental studies and the in vitro effect of ellagic acid on chronic myeloid leukemia cells Frutas vermelhas e leucemia: uma revisão sistemática de estudos experimentais e o efeito in vitro do ácido elágico sobre células de leucemia mieloide crônica

Effects of short-term high-intensity interval and continuous exercise training on body composition and cardiac function in obese sarcopenic rats

Life Sciences, 2020

We investigated the effects of high-intensity interval and continuous short-term exercise on body... more We investigated the effects of high-intensity interval and continuous short-term exercise on body composition and cardiac function after myocardial ischemia-reperfusion injury (IRI) in obese rats. Methods: Rats fed with a standard chow diet (SC) or high-fat diet (HFD) for 20 weeks underwent systolic blood pressure (SBP), glycemia and dual-energy X-ray absorptiometry analyses. Then, animals fed with HFD were subdivided into three groups: sedentary (HFD-SED); moderate-intensity continuous training (HFD-MICT); and high-intensity interval training (HFD-HIIT). Exercised groups underwent four isocaloric aerobic exercise sessions, in which HFD-MICT maintained the intensity continuously and HFD-HIIT alternated it. After exercise sessions, all groups underwent global IRI and myocardial infarct size (IS) was determined histologically. Fat and muscle mass were weighted, and protein levels involved in muscle metabolism were assessed in skeletal muscle. Results: HFD-fed versus SC-fed rats reduced lean body mass by 31% (P < 0.001), while SBP, glycemia and body fat percentage were increased by 10% (P = 0.04), 30% (P = 0.006) and 54% (P < 0.001); respectively. HFDinduced muscle atrophy was restored in exercised groups, as only HFD-SED presented lower gastrocnemius (32%; P = 0.001) and quadriceps mass (62%; P < 0.001) than SC. PGC1-α expression was 2.7-fold higher in HFD-HIIT versus HFD-SED (P = 0.04), whereas HFD-HIIT and HFD-MICT exhibited 1.7-fold increase in p-mTOR Ser2481 levels compared to HFD-SED (P = 0.04). Although no difference was detected among groups for IS (P = 0.30), only HFD-HIIT preserved left-ventricle developed pressure after IRI (+0.7 mmHg; P = 0.9). Significance: Short-term exercise, continuous or HIIT, restored HFD-induced muscle atrophy and increased mTOR expression, but only HIIT maintained myocardial contractility following IRI in obese animals.