Fadime Sultan Albez

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Andrej Dujella

University of Zagreb

Hemin Koyi

Uppsala University

Jana Javornik

University of East London

Graham Martin

University of Leicester

Gwen Robbins Schug

University of North Carolina at Greensboro

Gabriel Gutierrez-Alonso

University of Salamanca

John Sutton

Macquarie University

Eros Carvalho

Universidade Federal do Rio Grande do Sul

Kevin Arbuckle

Swansea University

Jesper Hoffmeyer

University of Copenhagen

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Papers by Fadime Sultan Albez

Long-term follow-up of young denim sandblasters in Turkey

Occupational Medicine

Background Denim sandblasting-induced silicosis is a recently identified occupational disease. Ai... more Background Denim sandblasting-induced silicosis is a recently identified occupational disease. Aims In this study, we aimed to evaluate pulmonary and radiological changes in the long-term follow-up of former denim sandblasters. Methods Ninety former denim sandblasters were followed from 2007 to 2018. Chest X-rays were evaluated according to the International Labour Organization (ILO) classification. Baseline and final data were compared. Silicosis prevalence, radiological progression and pulmonary dysfunction were evaluated. Results All of the sandblasters were men. Their mean age was 34 ± 5 years, mean follow-up time was 9 ± 2 years (mean time since initial exposure: 17 ± 2 years) and mean duration of exposure was 34 ± 25 months. Rates of radiological progression and decline in pulmonary during follow-up were 63% and 39%, respectively. During follow-up, all patients were diagnosed with silicosis. All workers who were ILO category 0 at baseline (n = 26, 29%) progressed to higher cat...

The association of silicosis severity with pectoralis major muscle and subcutaneous fat volumes, and the pulmonary artery/aorta ratio evaluated by CT

Diagnostic and Interventional Radiology

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Is elevated mean platelet volume predictive of pulmonary embolism recurrence?

Pulmonary Circulation and Pulmonary Vascular Disease

STING-dependent sensing of self-DNA drives silica-induced lung inflammation

Nature Communications

Silica particles induce lung inflammation and fibrosis. Here we show that stimulator of interfero... more Silica particles induce lung inflammation and fibrosis. Here we show that stimulator of interferon genes (STING) is essential for silica-induced lung inflammation. In mice, silica induces lung cell death and self-dsDNA release in the bronchoalveolar space that activates STING pathway. Degradation of extracellular self-dsDNA by DNase I inhibits silica-induced STING activation and the downstream type I IFN response. Patients with silicosis have increased circulating dsDNA and CXCL10 in sputum, and patients with fibrotic interstitial lung disease display STING activation and CXCL10 in the lung. In vitro, while mitochondrial dsDNA is sensed by cGAS-STING in dendritic cells, in macrophages extracellular dsDNA activates STING independent of cGAS after silica exposure. These results reveal an essential function of STING-mediated self-dsDNA sensing after silica exposure, and identify DNase I as a potential therapy for silica-induced lung inflammation.

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Predictive Value of Mean Platelet Volume for Pulmonary Embolism Recurrence

Lung, 2017

Recurrence is a major clinical problem in patients with pulmonary embolism and can affect mortali... more Recurrence is a major clinical problem in patients with pulmonary embolism and can affect mortality. The decision to discontinue treatment is important for recurrence and is based on patients' clinical features as well as certain blood parameters. Our aim in this study was to evaluate whether mean platelet volume (MPV) and platelet distribution width (PDW) have utility as new predictive parameters for recurrence and mortality in pulmonary embolism. A total of 440 patients with pulmonary embolism underwent computed tomography, Doppler ultrasonography, and echocardiography before and at the conclusion of treatment. Thrombocyte count, MPV, PDW, and D-dimer parameters were also evaluated at the same time points. MPV and PDW were significantly higher in deceased patients (8.8 ± 1.2 fl and 17.4 ± 0.8) compared to surviving patients (7.7 ± 0.9 fl and 17 ± 0.9) (p < 0.0001). Initial MPV and PDW were also significantly higher in patients with recurrence (8.4 ± 0.7 vs 7.6 ± 0.8 fl, p &...

Books by Fadime Sultan Albez

SAĞLIK HİZMETLERİNDE ÖZEL İLGİ GRUPLARI VE DEZAVANTAJLI GRUPLARLA İLETİŞİM (Sağlık Profesyonelleri İçin Pratik Rehber)

by Fadime Sultan Albez and Erol Özmen

Sağlık hizmetlerinde özel ilgi grupları ve dezavantajlı gruplarla iletişim odaklı bu kitabımızda,... more Sağlık hizmetlerinde özel ilgi grupları ve dezavantajlı gruplarla iletişim odaklı bu kitabımızda, alanın uzmanı yazarlarımız; hekimler, hemşireler ve diğer sağlık çalışanlarına, hastalar ve hasta yakınlarıyla iletişim ve ilişkilerde yararlanılabilecek bilgi ve deneyimlerini aktarmaktalar.

Kitapta şu konulara ilişkin hem dikkat edilmesi gerekenlere hem de pratik uygulama örneklerine yer verilmektedir:

Sağlık Profesyonelleri İçin İletişim Becerileri ● Sağlık Profesyonelleri İçin Kendini, Hasta ve Yakınlarını Tanıma Bilgi ve Becerileri ● Çocuklarla İletişim ● İstismara Uğramış Çocuklarla İletişim ● Ergen Hastalarla İletişim ● Gebeler ve Lohusalarla İletişim ● Yaşlı Hastalarla İletişim ● İşitme Kayıplı Hastalarla İletişim ● Dil ve Konuşma Engellilerle İletişim ● Görme Engellilerle İletişim ● Zihinsel Engellilerle İletişim ● Down Sendromlu Bireylerle İletişim ● Bulaşıcı Hastalığı Olan Hastalarla İletişim ● Kronik Hastalarla İletişim ● Fiziksel Engellilerle (Ortopedik ve Felçli Hastalarla) İletişim ● Kanser Hastaları İle İletişim ● Organ Nakli Bekleyen Hastalarla İletişim ● Terminal Dönemdeki Hastayla İletişim ● Afetzedelerle İletişim ● HIV/AIDS ile Yaşayan Birey ve Hastalarla İletişim ● LGBTQIA+ Hastalar ile İletişim ● Bağımlılarla İletişim ● Adli Tıp Uygulumalarında İletişim ● Şiddet Mağduru Kadınlarla İletişim ● Göçmen Hastalarla İletişim ● Etnik Kimlik veya İnanç Kaynaklı Dezavantaj Yaşayan Hastalarla İletişim.

Long-term follow-up of young denim sandblasters in Turkey

Occupational Medicine