anjali sabnis

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DrArpan Haldar

All India Institute of Medical Sciences, Bhubaneswar

DrArpan Haldar

All India Institute of Medical Sciences, Bhubaneswar

Journal of Pharmacy and Pharmacology

VIJAYA LAKSHMI GADDAM

Zubair Jaji

SONALI THOMAS

Kumaon University

Fares Mohamed Amine

University mohamed cherif messaadia. Souk-Ahras. Algeria

Nic Kamolthepprithoon

Capital Medical University

Prabhakar Kumar

Amravati University

rajeev mukhia

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Papers by anjali sabnis

Ambiguous Genitalia : A Case Report

When the sex of the newborn child cannot be decided then it is called as ambiguous genitalia. Thi... more When the sex of the newborn child cannot be decided then it is called as ambiguous genitalia. This becomes very much stressful and serious condition for parents and doctors for which immediate and multidisciplinary approach is expected. Hormonal and genetic factors play crucial role in disorder of sex development. Case: We present a case of ambiguous genitalia with omphalocele. Blood sample of new born baby was sent to Cytogenetic laboratory for sex determination. Along with ambiguous genitalia, omphalocele, presence of uterus and testis on sonography, patent ductus arteriosus was present. Karyotyping was done which revealed 46, XY, add 5p (15.3). The hypothesis of relation between karyotyping report and clinical symptoms is presented in this case. Conclusion: Karyotyping is a gold standard method in case of ambiguous genitalia.

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Anatomical Variations of Long Tendons of the Thumb

International journal of current research and review, 2013

Thumb has attained a lot of attraction because of its functional significance. In today’s hitechn... more Thumb has attained a lot of attraction because of its functional significance. In today’s hitechnical era thumb movements have become prime movements which are possible because of the thenar muscles, Extensor pollicis longus (EPL), Extensor pollicis brevis (EPB) and Abductor pollicis longus (APL). Variations in their arrangement, number, origin and insertion are very important in thumb surgery. 50 upper limbs of 25 cadavers of unknown sex were studied to find out any variations in EPL, EPB and APL. In four cadavers we have found variations in EPL, EPB and APL unilaterally.

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Morphological Study of Fetal Thyroid Gland in Different Gestational Ages

International journal of scientific research, 2016

This study was performed on 40 spontaneously aborted human fetuses aged between 13 and 40 weeks o... more This study was performed on 40 spontaneously aborted human fetuses aged between 13 and 40 weeks of gestation. Fetuses without any external and internal pathology or anomaly were included in this study. Fetuses were divided into seven groups based on gestational ages as follows: first group 13-16 weeks, second group 17-20 weeks, third group 21-24 weeks, fourth group 25-28 weeks, fifth group 29-32 weeks, sixth group 33-36 weeks and seventh group 37-40 weeks. The dimensions (length,width, thickness and weight) of the fetal thyroid glands were determined by vernier caliper instrument. The dimensions and ratios of the fetal thyroid gland (weight/fetal body weight) were evaluated.The dimensions of fetal thyroid glands increased with gestational age. This study gives knowledge of thyroid growth differentiation in different gestational ages.

Morphological study of eyeball in developing human foetuses

Research Paper Commerce Medical Science Morphological and Morphometric Study of Human Foetal Spleen at Different Gestational Age

A Rare Case: Duplication of Lungs on Left Side in Human Cadaveric Study

International Journal of Anatomical Variations, 2021

Knowledge of lung variation is essential to all medical professionals to exactly interpret radiog... more Knowledge of lung variation is essential to all medical professionals to exactly interpret radiographs, computed tomography scans, to diagnose, plan and modify a surgical procedure. In this case, a very rare variation has been studied, where three lungs were present in a cadaver. There was a duplication of lungs on left side, none of them had a fissure. Whereas, right lung had normal gross anatomical features. Such variation has not been reported till date. It should be taken into consideration while interpreting radiological variations and during surgeries like lobectomy, segmentectomies.

Morphological study of cutaneous ligaments

The cutaneous ligaments of phalanges of palm and foot are fine and sender fibrous strips running ... more The cutaneous ligaments of phalanges of palm and foot are fine and sender fibrous strips running from tendon sheath to skin over phalanges. Different opinions regarding cutaneous ligaments have created interest to find out the structure of them. By keeping aim in the mind to study ligaments in relation to attachment, thickness, length and histological structure, a study was conducted on 80 digits of 8 cadavers. These ligaments are running in relation to ventral and dorsal aspect of the digital nerve from tendon sheath to the skin. Attachment of the ligaments to the skin is suggestive of stabilization of skin during movements. The morphological data of cutaneous ligaments will be helpful in surgical implication of Duputren’s Contracture, replantation and revascularization of the digit. Thus clinical significance of cutaneous ligaments has attracted vascular surgeons in microsurgery of hand.

Comparative Study of Thickness of Tunica Media of Umbilical Cord Vessels in Normal and Pih Patients

International journal of scientific research, 2016

Aim and Objectives: To compare the thickness of tunica media of umbilical cord vessels in normal ... more Aim and Objectives: To compare the thickness of tunica media of umbilical cord vessels in normal and PIH patients on histological basis. 1. 1. To calculate thickness of tunica media of umbilical cord vessels in normal patients. 2. 2. To calculate thickness of tunica media of umbilical cord vessels in PIH patients. 3. 3. Compare between thickness of tunica media in normal and PIH patients. Materials : The study sampled 30 normal placenta with umbilical cord and 30 placenta with umbilical cord from PIH patients are included in the study. Methods : After delivery, the umbilical cord with placenta were collected from labour room of MGM Hospital, Kalamboli, Navi Mumbai and fixed in 10% formalin solution. For Histology – Standard procedure was used and H & E stain was used. The thickness of tunica media was measured with micrometer eyepiece.

A CASE REPORT ON MATERNAL t (1;2) (q11; p11.1) AND ITS INHERITANCE

Balanced translocation in one of the partnersmay form faulty gametes and so it may be associated ... more Balanced translocation in one of the partnersmay form faulty gametes and so it may be associated with infertility or recurrent miscarriages. Although, if same balanced translocation gets inherited then it gives rise to normal child. We report a case of non-consanguineous couple with the history of spontaneous abortion with bilateral dysplastic kidney in the foetus. Karyotyping of husband was normal and wife showed autosomal balanced translocation between q arm (11) of chromosome 1 and p arm (11.1) of chromosome 2. After doing genetic counselling for prenatal diagnosis, couple underwent prenatal diagnosis by chorionic villous and amniotic culture in two pregnancies respectively. In the irst pregnancy, the female foetus inherited same translocation which mother carried and in the second pregnancy, male foetus inherited normal chromosomes frommother. Genetic counselling was done during both the pregnancies and couples continued the pregnancy. Inheritance of balanced translocation andno...

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Anatomical variations in suprascapular notch

A case report on additional branch of mandibular nerve

Anatomical variations related to lingual, mandibular, inferior alveolar nerve are of great intere... more Anatomical variations related to lingual, mandibular, inferior alveolar nerve are of great interest to dentist. During routine cadaveric dissection of infratemporal fossa of an adult male in the Department of Anatomy, an additional branch of mandibular nerve was found on the right side. Difficulties in failure of local anaesthesia can create hurdles during dental procedures. Such anatomical variations related to mandibular nerve are of clinical significance for dentist and oral maxillofacial surgeons while giving local anesthesia. © Int J Anat Var (IJAV). 2013; 6: 197–198.

Morphological Study of Cutaneous Ligaments of Phalanges Estudio Morfológico de los Ligamentos Cutáneos de las Falanges

Anjali SabnisSABNIS, A. Morphological study of cutaneous ligaments of phalanges. Int. J. Morphol.... more Anjali SabnisSABNIS, A. Morphological study of cutaneous ligaments of phalanges. Int. J. Morphol., 31(2):606-608, 2013.SUMMARY: The cutaneous ligaments of phalanges of palm and foot are fine and sender fibrous strips running from tendonsheath to flexor and extensor aspect of skin over phalanges. They are playing important role in stabilizing skin during movements andsupporting digital neurovascular bundle. Such ligaments have carried lot of surgical value in microsurgery of hand. The morphol ogy ofsuch ligaments is studied in 80 digits of 8 cadavers of 20-80 years (6 males and 2 females). They are studied in detail in terms ofattachments, thickness & length. The morphological data will be helpful in surgical implication of Duputren’s Contracture, repl antation,revascularization of the digit.KEY WORDS: Cutaneous ligaments; Cleland’s ligament; Grayson’s ligaments; Duputren’s contracture.

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A Case of Partial Trisomy of 10q and Partial Monosomy of 6p Resulting from Maternal t(6;10) (p23;q24)

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Chromosomal analysis is practiced routinely since long time in congenital malformations to find o... more Chromosomal analysis is practiced routinely since long time in congenital malformations to find out structural and or numerical chromosomal aberrations. Translocation is one of the structural chromosomal aberrations where exchange of genetic material between the chromosomes is seen because of two breakpoints. On the basis of involvement of type of chromosome, two different types of translocation are defined. A case of two-year-old girl child with the history of developmental delay, generalised hypotonia and recurrent infections was reported whose cytogenetic analysis showed additional genetic material on ‘p’ arm of one chromosome 6. To find out the additional genetic material, parental chromosomal study was done which revealed balanced translocation between ‘q’ arm of chromosome 10 and ‘p’ arm of chromosome 6 and normal chromosomal pattern in father. Balanced translocation in mother gave rise to formation of derivative chromosome 6 which was transmitted to daughter causing partial t...

Anatomical variations of sulci in human fetal cerebrum and its clinical significance

Biomedicine

Introduction and Aim: Appearance of sulci and its number in the fetal cerebrum is a signal of gro... more Introduction and Aim: Appearance of sulci and its number in the fetal cerebrum is a signal of growth and development. Chronological appearance and symmetrical development of sulci corresponds to gestational age of fetus. Few sulci can be visualized in the prenatal period to judge the growth of fetus. Any change in chronological appearance, symmetry and number of sulci in fetal cerebrum is of prime importance. Materials and Methods: Hundred and six cerebral hemispheres of 53 fetal brains of different gestational ages were collected from MGM Hospital Kalamboli and Aurangabad after institutional ethical approval to study the pattern of sulci on both sides after fixing in 10% formalin. Results: In 6 (5.6 %) cerebral hemispheres variation in appearance of sulci was observed. It was noted that there is change in number of superior temporal sulcus (STS), superior frontal sulcus (SFS), parieto-occipital sulcus (POS), calcarine sulcus (CS) and occipitotemporal sulcus (OTS) on both the si...

Proliferative capacity of retinal progenitor cells in human fetal retina

Journal of the Anatomical Society of India

Introduction: Retina is an innermost, delicate, and photosensitive layer of the eyeball, which is... more Introduction: Retina is an innermost, delicate, and photosensitive layer of the eyeball, which is composed of 10 layers and 8 specialized cells which are involved in paramount function of the body like vision. Retinal neurogenesis commences from the layers of optic cup, which forms from optic vesicle. Progenitor cells are the tissue-specific cells which give rise to all different types of retinal cells. Progenitor cells in fetal retina proliferate at specific time during development of retina. Knowledge of the highest proliferative capacity interval of progenitor cells will be valuable for transplantation. Material and Methods: Twenty-eight fetuses of spontaneous abortions of 13th–40th week were collected from MGM Hospital after ethical and scientific approval of the institute. After fixation of fetuses, eyeballs were extracted and fixed in buffer solution. Sections were taken and the retina was treated with Ki-67 immunohistochemistry marker to observe proliferative capacity of retinal progenitor cells (RPCs). Seven groups (A to G) of 4 weeks were made and observations of each group were noted. Results: It was observed that the highest proliferative capacity of RPCs was in B group (17–20 weeks) and the highest proliferative capacity of RPCs was maximum at 19th week of gestation. Discussion and Conclusion: Characteristics of progenitor cells in retina are well studied. Their highest proliferation period can be utilized to make the procedure of transplantation more refined.

A Case Report on Excessive Elongation of Styloid Process

Indian Journal of Anatomy

Foramen in Xiphoid Process of Sternum

International Journal of Research -GRANTHAALAYAH

Xiphoid process is smallest and distal component of manubrium sternum which is located in epigast... more Xiphoid process is smallest and distal component of manubrium sternum which is located in epigastrium. Variations in size and shape of xiphoid process are commonly observed. During teaching sternum to 1st M.B.B.S. students of MGM Medical College, Navi Mumbai, two small foramina in two different xiphoid processes were noticed. Though presence of foramen in xiphoid process is not uncommon, their presence should not be ignored. During assessment of injuries in autopsy, post-mortem examination and radiological reporting knowledge of xiphoid process and foramina in xiphoid process will be helpful.

A case report on ossified thyroid cartilage

The Journal of Medical Research

During retrieval of bones from 44 years male cadaver in the department of Anatomy of MGM Medical ... more During retrieval of bones from 44 years male cadaver in the department of Anatomy of MGM Medical Navi Mumbai, we observed thyroid cartilage was completely ossified. Thyroid cartilage is largest hyaline cartilage of larynx which gives attachment to muscles, membrane and ligaments. It also protects vocal cords which is a very important function of thyroid cartilage. Ossification of thyroid cartilage is rare phenomenon and knowledge regarding it should not be ignored.

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A Study of the Growth of Human Foetal Lung in Relation with the Gestational Age

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

A Study of Prevalence of Sacralization of L5 Vertebra

International Journal of Anatomy and Research

Sacrum is centrally located unpaired bone of pelvis which is composed of 5 sacral vertebrae. Supe... more Sacrum is centrally located unpaired bone of pelvis which is composed of 5 sacral vertebrae. Superiorly it articulates with 5 th lumbar vertebra to form lumbosacral joint and laterally it articulates with hip bone to form sacroiliac joint. When 5 th lumbar vertebra fuses with 1 st sacral vertebra then it is called as sacralization and when 1 st sacral vertebra gets separated from sacrum then it is called as lumbarization. 79sacra from the department of Anatomy of MGM medical college and D. Y. Patil medical college, Navi Mumbai were studied to see sacralization. Out of 79 sacra in 14sacra(17.7 %) sacralization was observed.Out of 14 sacra, 4 sacra showed bilateral and complete sacralization, 5 sacra showed unilateral and partial sacralization and 5 sacra showedincomplete fusion between L5 and S1 vertebra. Change in normal structure of lumbar vertebra and sacrum may lead to alteration in kinematics of lumbosacral region which may lead to compression of nerve and low back pain. Knowledge regarding incidence of sacralization will be useful for radiologist and orthopaedic surgeon while dealing with low back pain.

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Ambiguous Genitalia : A Case Report