Papers by Xiao Zhu Pei Pei
1997 IEEE International Conference on Intelligent Processing Systems (Cat. No.97TH8335)
This paper establishes a dcveloping systcm of car door lock with catch in virtual environment to ... more This paper establishes a dcveloping systcm of car door lock with catch in virtual environment to mcct the requirements of virtual manufacturing for virtual rcality urgently needed by Chinese enterpriseb. The application of virtual reality to product development of automobile parts and spares is thus discussed.
Design of a Four-Effect Desalination Demonstration Plant Using Waste Heat from a Diesel Engine
Advanced Materials Research, 2014
The advantages and disadvantages of the conventional desalination methods were discussed. A four-... more The advantages and disadvantages of the conventional desalination methods were discussed. A four-effect desalination demonstration plant using waste heat from a diesel engine was designed. Not only the water yield but also the physical dimension of the distiller has been calculated under the operating condition. The analysis of energy consumption shows that the desalination system is low-cost.
Study on the Key Elements of Chinese Enterprises' Management Innovation Based on the Principal Component Analysis
Applied Mechanics and Materials, 2014
In order to identify the key factors influencing the development of China's enterprise manage... more In order to identify the key factors influencing the development of China's enterprise management innovation and study the interaction between them. 23 factors concerning management innovation are analyzed with the method of principal component analysis on the basis of the former research. The analytical results show that enterprise supply chain management method, enterprise field management method, enterprise performance management method, enterprise quality management, enterprise production management, enterprise process management are the key factors in management innovation. Paying more attention on the key factors helps to capture the principal contradiction, and to improve the efficiency of the analysis on enterprise management innovation.
Development and Application of a New Al-Si-Mg Alloy for Semi-Solid Forming
Advanced Materials Research, 2012
Based on A356, development and application of a new Al-Si-Mg alloy had been studied, aimed to get... more Based on A356, development and application of a new Al-Si-Mg alloy had been studied, aimed to get an alloy with excellent mechanical property and suitable for semi-solid forming. An adjustment of Mg content is made, from 1% to 2.5%, to ensure the composition range. The temperature range of semi-solid alloys can be obtained through the phase calculation on the alloys with T-cal, a kind of thermodynamic software. The accuracy of phase can be verified with differential scanning calorimeter (DSC). The chosen alloys are melted to be prepared for specimens, followed by mechanical testing. Finally, the optimal composition can be got according to mechanical properties, to be used for electromagnetic continuous casting, followed by the induction reheating and thixotropic semi-solid forming process. The law analyses were discussed during the induction reheating for Al-Si-Mg alloy and A356.
CFD Study on the Factors Influencing the Performance of PV-Integrated Double-Skin Façade Channel
Applied Mechanics and Materials, 2014
Several factors influencing the performance of PV-integrated double-skin façade were analyzed. W... more Several factors influencing the performance of PV-integrated double-skin façade were analyzed. We used CFD numerical method to investigate the influence of width, height, outlet size and the angle of photovoltaic plate on the performance of PV channel based on the summer typical meteorological parameter. The PV-integrated double-skin façade were installed at east orientation in Shanghai. The recommended value of height and other factors were obtained. Height and the angle of photovoltaic plate were two most important factors which should be considered specially in the design of PV-integrated double-skin façade.
Experimental Studies on a Solar Low Temperature Multi-Effect Distillation Desalination System
Advanced Materials Research, 2014
Solar energy has been widely used in desalination systems. A low-temperature multi-effect desalin... more Solar energy has been widely used in desalination systems. A low-temperature multi-effect desalination system driven by solar is constructed for a series of experimental studies. The results show that water production rate grows with solar radiation, and maintains at a high level between 12am to 4pm. The optimized heat water flow is 1400 kg/h and appropriate cooling water temperature is 24 °C, respectively.
Parkinson's disease-like forelimb akinesia induced by BmK I, a sodium channel modulator
Behavioural brain research, Jul 15, 2016
Parkinson's disease (PD) is a neurodegenerative disorder and characterized by motor disabilit... more Parkinson's disease (PD) is a neurodegenerative disorder and characterized by motor disabilities which are mostly linked with high levels of synchronous oscillations in the basal ganglia neurons. Voltage-gated sodium channels (VGSCs) play a vital role in the abnormal electrical activity of neurons in the globus pallidus (GP) and the subthalamic nucleus (STN) in PD. BmK I, a α-like toxin purified from the Chinese scorpion Buthus martensi Karsch, has been identified a site-3-specific modulator of VGSCs. The present study shows that forelimb akinesia can be induced by the injection of BmK I into the globus pallidus (GP) in rats. In addition, BmK I cannot produce neuronal damage in vivo and in vitro at 24h after treatment, indicating that the forelimb akinesia does not result from neuronal damage. Electrophysiological studies further revealed that the inactivated Na(+) currents were showed to be more vulnerably modulated by BmK I than the activated Na(+) currents in human neuron-lik...
Protective effects of desacyl ghrelin on doxorubicin-induced and diabetic cardiomyopathy
Research on the Product Whole Lifecycle Management under the Perspective of Integrated Innovation
2011 International Conference on Management and Service Science, 2011
Integration is the trend of innovation. Enterprise resources can be optimized allocation through ... more Integration is the trend of innovation. Enterprise resources can be optimized allocation through integration innovation. In this paper, the Innovative Approaches will be integrated into product whole lifecycle management with the theory of integrated innovation, and a integration system based on innovation approaches will be built in product lifecycle.
Advanced Materials Research, 2012
A novel sample rate adaptation technique is proposed for the wireless sensor/actuator networks wi... more A novel sample rate adaptation technique is proposed for the wireless sensor/actuator networks with packet reordering. Considering network-induced delay and packet loss, a new technique for adapting the sampling interval to network parameters is studied in terms of the Reorder Density, such that a closed-loop switched delay system is presented by constructing state feedback controller. Furthermore, a criterion for stochastic stability of WSAN s is derived based on the stochastic theory due to the subsystems subject to Markov chain. An adaptive controller is designed by solving linear matrix inequalities (LMI). An example is given to show the eff与ctiveness of the proposed method.
Study on the Formability and Friction of Hot Forging Process of a Spur Gear Shaft for Manufacturing Engineering
Advanced Materials Research, 2012
Hot forging processes of a spur gear shaft with three billet sizes are simulated using FEM. The b... more Hot forging processes of a spur gear shaft with three billet sizes are simulated using FEM. The billet with size of φ36*60 has the best formability in hot forging the spur gear shaft. The effects of the initial billet temperature and the friction coefficient on the hot forging formability of the spur gear shaft are obtained respectively through simulation. Hot forging experiments are carried out and experimental results show good agreement with those in simulation. At last, the reasonable hot forging parameters of the spur gear shaft for manufacturing engineering are suggested as follows: billet size of φ36*60, billet initial temperature of 1050°C and friction coefficient of 0.3.
Autophagic Adaptations to Long-term Habitual Exercise in Cardiac Muscle
International Journal of Sports Medicine, 2015
Autophagy has been shown to be responsive to physical exercise. However, the effects of prolonged... more Autophagy has been shown to be responsive to physical exercise. However, the effects of prolonged habitual exercise on autophagy in cardiac muscle remain unknown. The present study aimed to examine whether long-term habitual exercise alters the basal autophagic signalling in cardiac muscle. Female Sprague-Dawley rats aged 2 months were randomly assigned to control and exercise groups. Animals in exercise group were kept in cages with free access exercise wheels to perform habitual exercise for 5 months. Animals in the control group were placed in cages without exercise wheels. Ventricular muscle tissues were harvested for analysis after 5 months. Phosphorylation statuses of upstream autophagic regulatory proteins and protein expressions of downstream autophagic facts remained unchanged in the cardiac muscle of exercise animals when compared to control animals. Intriguingly, the protein abundance of microtubule-associated protein-1 light chain -3 II (LC3-II), heat shock protein 72 (HSP72) and peroxisome proliferator-activated receptor-gamma coactivator (PGC-1α) were significantly increased in cardiac muscle of exercise rats relative to control rats. 5 months of habitual exercise causes the adaptive increase in LC3-II reserve without altering autophagic flux, which probably contributes to the elevation of cellular autophagic capacity and efficiency of cardiac muscle.
Research on Fabricating Technology of Three Dimensional Integrated Braided Composite I Beam
Advanced Materials Research, 2010
In this paper the fabricating technology of three dimensional (3D) integrated braided composite I... more In this paper the fabricating technology of three dimensional (3D) integrated braided composite I beam is researched, including: braiding technology of 3D braided I beam preform, the orientation of fiber-tow in the I beam preform, the optimizing of process parameters of resin transfer molding (RTM) for 3D braided composite I beam, and the design of mould for consolidation of composite I beam. The quality of 3D braided composites is good analyzed by ultrasonic A-scan, void content calculation and microscope observation. The research result will provide a good way for designing and fabricating high performance 3D integrated braided composite components with irregular cross section.
Flow Characteristics of Tip Clearance in Axial Compressor
Applied Mechanics and Materials, 2015
Tip clearance of compressor rotor blade is introduced for avoiding friction collision between the... more Tip clearance of compressor rotor blade is introduced for avoiding friction collision between the moving blade and the casing. Because of the existence of the pressure difference between pressure surfaces and the suction surfaces of the blade, the blending of the leakage flow with the mainstream causes losses, which affects internal flow field and overall performance of the compressor. In this article, numerical analysis software is used to study the multi-condition performance of a six and a half axial flow compressor, for analyzing the impact of leakage flow patterns on compressor.
Research on Application of Building Photovoltaic System in Shanghai - Taking Chenjia Town as an Example
Applied Mechanics and Materials, 2014
The goal of this paper is to discuss whether building photovoltaic systems are suitable to be app... more The goal of this paper is to discuss whether building photovoltaic systems are suitable to be applied in Shanghai and Chenjiazhen in Chongming Island is taken as a typical example to be researched. Practical running data tested from building photovoltaic system of Chenjia Town ecological building and planning design of Building Integrated PV in Chenjia Town international ecological community were analysed. The research result was positive to use this energy system. Therefore, when new buildings in similar areas are planned to be designed, the designers should pay more attention to the applicable possibility of Building Integrated PV, which is beneficial to boost the use of renewable energy.
Scheduling Sensor Transactions to Maintain Data Temporal Validity
2008 International Conference on Computer Science and Software Engineering, 2008
Sensor transactions should be scheduled to preserve the temporal validity constraint of real-time... more Sensor transactions should be scheduled to preserve the temporal validity constraint of real-time data. In this paper, we propose a new algorithm called deferrable scheduling using time slice exchange. It defers the release time of a transaction instance as late as possible by exchanging its time slices with time slices for other transaction instances. Experiments show that it outperforms the
Advanced Engineering Forum, 2011
This paper briefly introduce the concept and characteristic and form of machine vision inspecting... more This paper briefly introduce the concept and characteristic and form of machine vision inspecting system, elaborate its application in industry, the present status and development prospects of the application in geometry measurement are described in detail, and deal with emphatically its critical technical points and the corresponding solutions. 1. People will be freed from repeated and tedious work. 2. Reduced labor costs. 3. Put up productivity and detection accuracy. 4. To achieve flexible manufacturing. Based on a lot of technical literature both abroad and domestic, this paper makes a brief description of machine vision systems and mainly discussed the detection of machine vision in industrial research and application.
Research on Effectiveness of Production Resource Allocation Based on Extended Information Entropy
Applied Mechanics and Materials, 2014
The effective resource allocation in production system is the key to high performance. This paper... more The effective resource allocation in production system is the key to high performance. This paper firstly analyses the entropy increase which damages the factors’ operation, then the information entropy theory is extended to establish a complexity model based on size, difficulty, and state diversity. On the basis of complexity, the decline of factors’ utilization efficiency is described. Moreover, some specific management methods are introduced to illustrate the importance of complexity control.
Investigation of Sodium Hyaluronate/ Konjac Glucomannan Blend Films
Advanced Materials Research, 2012
The blend films were fabricated via blending sodium hyaluronate (SH) and Konjac glucomannan (KGM)... more The blend films were fabricated via blending sodium hyaluronate (SH) and Konjac glucomannan (KGM). Lactic acid was applied as modifier and the mixture of Ammonia and anhydrous alcohol as cross-linker. The influencing factors were analyzed via the orthogonal experiment L16(4,5). It was shown that the water absorption of the blend films was around 151%~608%. Tensile strength and elongation of the blend film samples reached about 11.3~20.7MPa and 10.8~20.2% respectively. The degradation rate declined obviously compared with the simple use of the SH. XRD and IR spectra indicated that crystallinity of the blend films was enhanced slightly after cross-linking. The blend films were co-cultured with bone mesenchymal stem cells. It was demonstrated that the films could support the growth of cells and were non-toxicity and good biocompatibility.
![Research paper thumbnail of [D-Lys3]-GHRP-6 exhibits pro-autophagic effects on skeletal muscle](https://attachments.academia-assets.com/99177807/thumbnails/1.jpg)
Molecular and Cellular Endocrinology, 2015
Lys3]-GHRP-6 is regarded as a highly selective growth-hormone secretagogue receptor (GHSR) antago... more Lys3]-GHRP-6 is regarded as a highly selective growth-hormone secretagogue receptor (GHSR) antagonist and has been widely used to investigate the dependency of GHSR-1a signalling mediated by acylated ghrelin. However, [D-Lys3]-GHRP-6 has been reported to influence other cellular processes which are unrelated to GHSR-1a. This study aimed to examine the effects of [D-Lys3]-GHRP-6 on autophagic and apoptotic cellular signalling in skeletal muscle. [D-Lys3]-GHRP-6 enhanced the autophagic signalling demonstrated by the increases in protein abundances of beclin-1 and LC3 II-to-LC3 1 ratio in both normal muscle and doxorubicin-injured muscle. [D-Lys3]-GHRP-6 reduced the activation of muscle apoptosis induced by doxorubicin. No histological abnormalities were observed in the [D-Lys3]-GHRP-6-treated muscle. Intriguingly, the doxorubicin-induced increase in centronucleated muscle fibres was not observed in muscle treated with [D-Lys3]-GHRP-6, suggesting the myoprotective effects of [D-Lys3]-GHRP-6 against doxorubicin injury. The [D-Lys3]-GHRP-6-induced activation of autophagy was found to be abolished by the co-treatment of CXCR4 antagonist, suggesting that the pro-autophagic effects of [D-Lys3]-GHRP-6 might be mediated through CXCR4. In conclusion, [D-Lys3]-GHRP-6 exhibits proautophagic effects on skeletal muscle under both normal and doxorubicin-injured conditions.
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Papers by Xiao Zhu Pei Pei