Papers by Wallace Dos Santos
Condições De Trabalho De Catadores De Recicláveis Do Lixão Do Distrito Federal
Proceedings of Safety, Health and Environment World Congress, Oct 7, 2013
Improved water and ions dynamics in a clayey soil amended with different types of agro-industrial waste biochar
Soil and Tillage Research
SARS CoV-2 seroprevalence and diagnostic accuracy during a COVID-19 outbreak in a major penitentiary complex in Brazil, June to July 2020
International Journal of Prisoner Health
Purpose This study aims to estimate the overall SARS-CoV-2 seroprevalence and evaluate the accura... more Purpose This study aims to estimate the overall SARS-CoV-2 seroprevalence and evaluate the accuracy of an antibody rapid test compared to a reference serological assay during a COVID-19 outbreak in a prison complex housing over 13,000 prisoners in Brasília. Design/methodology/approach The authors obtained a randomized, stratified representative sample of each prison unit and conducted a repeated serosurvey among prisoners between June and July 2020, using a lateral-flow immunochromatographic assay (LFIA). Samples were also retested using a chemiluminescence enzyme immunoassay (CLIA) to compare SARS-CoV-2 seroprevalence and 21-days incidence, as well as to estimate the overall infection fatality rate (IFR) and determine the diagnostic accuracy of the LFIA test. Findings This study identified 485 eligible individuals and enrolled 460 participants. Baseline and 21-days follow-up seroprevalence were estimated at 52.0% (95% CI 44.9–59.0) and 56.7% (95% CI 48.2–65.3) with LFIA; and 80.7% ...
The universal and equitable access to health is established in the Brazilian Federal Constitution... more The universal and equitable access to health is established in the Brazilian Federal Constitution of 1988 and must be guaranteed by the Brazilian Unified Health System – the Sistema Único de Saúde (SUS). The lack of professionals and the large regional differences in the distribution of human resources, mainly physicians, are factors that contribute to the non-fulfillment of the SUS principles. This article reports the experience of evaluation of the More Doctors Program (PMM) by a multidisciplinary team composed of 28 researchers, based on field work in 32 municipalities with 20% or more of the population in extreme poverty selected in all regions of Brazil (remote areas, far from capitals, and rural maroon communities), as well as analyzes of the 5,570 Brazilian municipalities based on the Ministry of Health databases. The research resulted in a vast scientific production, pointing out important results, such as broadening of access to health and reducing of avoidable hospitalizat...
Glycogenoses: An Overeview
Caderneta da criança (menina): passaporte da cidadania
Convenio de cooperacao da COCAM/MS com o Instituto Nacional de Saude da Mulher, da Crianca e do A... more Convenio de cooperacao da COCAM/MS com o Instituto Nacional de Saude da Mulher, da Crianca e do Adolescente Fernandes Figueira – FIOCRUZ – financiado pelo Fundo Nacional de Saude.
Os métodos estatísticos desempenham um papel crescente e importante em praticamente todas as fase... more Os métodos estatísticos desempenham um papel crescente e importante em praticamente todas as fases da realização de uma pesquisa. Por isso, a importância de relatar a vivência dos acadêmicos do 5º período de Educação Física Bacharelado no componente de bioestatística. O objetivo foi de registrar os resultados dos dados coletados e as experiências dos acadêmicos. Desenvolveu-se um trabalho escrito contendo os objetivos, a metodologia, os resultados com tabelas e gráfico e a conclusão do trabalho, bem como, uma apresentação em Power Point® para a socialização. Verificou-se que o método de aprendizagem por meio da teoria e da prática, foi eficiente para a aquisição de conhecimento dos acadêmicos sobre a bioestatística. Introdução Os métodos estatísticos desempenham um papel crescente e importante em praticamente todas as fases da realização de uma pesquisa.
Vivências do Estágio 1 na Gerência de Normalização de Serviços da Atenção Primária – GENSAP (SES-DF)
Introducao: O curso de graduacao em Saude Coletiva da Universidade de Brasilia contempla uma vari... more Introducao: O curso de graduacao em Saude Coletiva da Universidade de Brasilia contempla uma variedade de temas que visam formar um profissional de carater generalista e competente para lidar com a formulacao, organizacao, implementacao, avaliacao e monitoramento de politicas, projetos e servicos de saude, podendo assim, atuar em todos os niveis de complexidade do âmbito do Sistema Unico de Saude. Por ter esse carater multifacetado e por abarcar uma serie de conteudos das mais diversas areas, torna-se impreterivel que, ao decorrer da graduacao, os discentes exercitem e desenvolvam sua capacidade de articulacao a fim de auxiliar a suprir as demandas da saude, considerada uma das areas mais complexas no que tange a administracao publica. Posto isso, com a intencao de preparar os graduandos, as disciplinas de Seminarios e Praticas Integrativas e dos Estagios Supervisionados se configuram como espacos em que o estudante pode integrar e por em pratica os seus conhecimentos. Nessa perspec...
International Journal of Infectious Diseases, 2021
To assess SARS-CoV-2 prevalence and health outcomes among inmates over 60 years during a COVID-19... more To assess SARS-CoV-2 prevalence and health outcomes among inmates over 60 years during a COVID-19 outbreak in a major penitentiary complex in the Federal District, Brazil. Methods: A mass test campaign was performed on May 13, 2020, using antibody-detection rapid tests for asymptomatic inmates and reverse transcriptase-polymerase chain reaction testing for those who were symptomatic. Those with negative results were retested on June 16. Inmates were interviewed to characterise background health conditions and the presence of symptoms. Results: A total of 159 inmates were evaluated. In the first mass testing, 79.9% (127/159) of inmates had been infected, of whom 53.5% (68/127) reported symptoms. In the second testing round, 17 new cases were identified, increasing the total to 90.6% (144/159) of inmates with a positive result. Comorbidities were present in 67.3% of inmates; 2 hospitalisations and no COVID-related deaths were recorded. Conclusion: More than 90% of inmates aged >60 years were infected with SARS-CoV-2 during the outbreak. Periodic health monitoring, active case finding and early care for symptomatic patients contributed to positive post-infection outcomes. Such measures must be considered essential for the surveillance of COVID-19 in environments with limited capacity to promote social distance, such as penitentiary institutions.
SARS-CoV-2 Seroprevalence and Accuracy Diagnostic Evaluation During a Covid-19 Outbreak in a Major Penitentiary Complex in Brazil, June-July 2020: A Population-Based Study
SSRN Electronic Journal, 2021
Summary: The pandemic of COVID-19 has presented as a threat to prison systems worldwide, as overc... more Summary: The pandemic of COVID-19 has presented as a threat to prison systems worldwide, as overcrowding, limited possibility of social distancing and sanitary restrictions favouring viral spread. SARS-CoV-2 seroprevalence studies in prison settings are important tools to understand transmission and to develop control measures. We aimed to estimate the overall SARS-CoV-2 seroprevalence and evaluated the accuracy of an antibody rapid test compared to a reference serological assay during a COVID-19 outbreak in a prison complex housing over 13,000 inmates in Brasilia. Methods: We conducted a repeated serosurvey of IgM/IgG SARS-CoV-2 antibodies among inmates between June 17-July 1 (baseline) and July 8-22, 2020 (21-days follow-up). We obtained a randomized, stratified representative sample of each prison unit. Inmates who accepted to be part of the study were interviewed through a standardised questionnaire covering sociodemographic and clinical characteristics. Blood samples were collected from each participant for the evaluation of SARS-CoV-2 antibodies with a lateral-flow immunochromatographic assay (LFIA). Inmates with negative results in the first serosurvey were interviewed and tested for a second time to evaluate recent symptoms history and serological status 21 days later. Samples were also retested using a chemiluminescence enzyme immunoassay (CLIA) to compare SARS-CoV-2 seroprevalence and 21-days incidence, as well as to estimate the overall infection fatality rate (IFR) and determine the diagnostic accuracy of the LFIA test. Findings: We identified 485 eligible individuals and enrolled 460 participants (94.8%), distributed across four prison units. Baseline and 21-days follow-up seroprevalence were estimated at 52.0% (95%CI 44.9-59.0) and 56.7% (95%CI 48.2-65.3) with the LFIA test; and 80.7% (95%CI 74.1-87.3) and 81.1% (95%CI 74.4-87.8) with the CLIA test, with an overall IFR of 0.02%. There were 78.2% (95%CI 66.7-89.7) symptomatic inmates among the positive cases, and the main symptoms included changes in taste or smell, headache, and fever. Sensitivity and specificity of LFIA test were estimated at 43.4% and 83.3% for IgM; 46.5% and 91.5% for IgG; and 59.1% and 77.3% for combined tests. There was a fair agreement between LFIA and CLIA results (Kappa score 0.23). Interpretation: We found rapid viral spread and high seroprevalence of anti-SARS-CoV-2 antibodies within the prison complex. The occurrence of asymptomatic infection highlights the importance of periodic mass testing in addition to case-finding of symptomatic inmates, however the field performance of LFIA tests should be validated. We recommend that vaccination strategies consider the inclusion of persons deprived of liberty and prison staff in priority groups. Funding: EN, GASR, RH, WNA acknowledge the Brazilian Ministry of Education (MEC) for support the COVID-19 response by University of Brasilia (#23106.028855/2020-74). RH, WMR and WNA acknowledge the Federal District Research Foundation (FAP-DF) for grants that supported this research (# 00193-00000495/2020-72). GASR, JHC, WMR, WNA acknowledge the National Research Council (CNPq) for grants that supported this research (# 402957/2020-2) Declaration of Interest: None to declare. Ethical Approval: The study was part of an epidemiological investigation conducted by the Brazilian Field Epidemiology Training Program/Ministry of Health as a response to a public health emergency, and it is supported by the national law 8.080/1990. Moreover, all participants provided informed consent and ethics approval was obtained under the CONEP protocol number 37007220.1.0000.0008.
Emerging Infectious Diseases, 2021
An outbreak of coronavirus disease began in a large penitentiary complex in Brazil on April 1, 20... more An outbreak of coronavirus disease began in a large penitentiary complex in Brazil on April 1, 2020. By June 12, there were 1,057 confirmed cases among inmates and staff. Nine patients were hospitalized, and 3 died. Mean serial interval was ≈2.5 days; reproduction number range was 1.0-2.3. *Data available for 783 cases. †Data available for 401 cases. ‡Includes metabolic disorders, immunosuppression, psychiatric disease, and chronic hepatitis.
Effectiveness of different biochars in remediating a salt-affected Luvisol in Northeast Brazil
Biochar, 2021
Biochar has been proposed as a soil amendment to reclaim salt-affected soils. However, the evalua... more Biochar has been proposed as a soil amendment to reclaim salt-affected soils. However, the evaluation of the different biochar types in these soils is essential due to the significant variation among biochar feedstocks. In this study, biochars from sugarcane bagasse (SB), orange bagasse (OB), and corncob (CB) were applied alone and in the presence of gypsum (G) to test their potential to remediate a highly degraded saline-sodic soil in Brazil´s Northeast region. For that, we conducted a laboratory column-leaching experiment and a greenhouse study. After the column-leaching test, we analyzed the sodium adsorption ratio (SAR), the electrical conductivity of the saturation extract (ECe), the concentrations of major ions, and the exchangeable sodium percentage (ESP). Maize plants were grown in the leached soil in a greenhouse. Sugarcane- and corncob-derived biochars were more efficient than gypsum in reducing the soil salinity, bringing the indicators below threshold values, and optimizing soil reclamation time. Soil ECe, SAR, and ESP were reduced to 3.42 dS m−1, 1.64 (mmolc dm−3)0.5 and 4.86%, respectively, in the SB treatment; and to 3.19 dS m−1, 0.88 (mmolc dm−3)0.5 and 2.53%, respectively, in the CB treatment. Orange bagasse biochar did not effectively reduce the salinity indicators. All biochar treatments improved seed germination and plant growth. The SB, CB, SBG, and CBG treatments increased plant height (478–558%), shoot mass (783–983%), and root mass (386–500%), respectively. Therefore, the application of SB and CB is an effective alternative to remediate saline-sodic soils and to reduce the impact of soil salinity in the environment.
Rural and Remote Health, 2016
Introduction: The Mais Médicos program was introduced in 2013 with the aim of reducing the shorta... more Introduction: The Mais Médicos program was introduced in 2013 with the aim of reducing the shortage of doctors in priority regions and diminishing regional inequalities in health. One of the strategies has been to offer 3-year contracts for doctors to work in primary healthcare services in small towns, inland, rural, remote, and socially vulnerable areas. This report describes the program's implementation and the allocation of doctors to these target areas in 2014. Methods: To describe the provision of doctors in the first year of implementation, we compared the doctor-to-population ratio in the 5570 municipalities of Brazil before and after the program, based on the Federal Board of Medicine database (2013), and the official dataset provided by the Ministry of Health (2014). Results: In its first public call (July 2013) 3511 municipalities joined the Mais Médicos program, requesting a total of 15 460 doctors; although the program prioritizes the recruitment of Brazilians, only 1096 nationals enrolled and were hired, together with 522 foreign doctors. As a consequence, an international cooperation agreement was set in place to recruit Cuban doctors. In 12 months the program recruited 14 462 doctors: 79.0% Cubans, 15.9% Brazilians and 5.1% of other nationalities, covering 93.5% of the doctors demanded; they were assigned to all the 3785 municipalities enrolled. The study reveals a major decrease in the number of municipalities with fewer than 0.1 doctors per thousand inhabitants, which dropped from 374 in 2013 to 95 in 2014 (75% reduction). Of the total, 294 doctors were sent to work in the country's 34 Indigenous Health Districts (100% coverage) and 3390 doctors were deployed in municipalities containing certified rural maroon communities (formed centuries ago by runaway slaves). After 1 year of implementation, the municipalities with maroon communities with less than 0.1 doctors per © James Cook University 2016, http://www.jcu.edu.au 2 thousand inhabitants were reduced by 87% in the poorest north region. More than 30% of municipalities with maroon communities in the richest regions had more than 1.0 doctors per thousand inhabitants, whereas in the poorest regions fewer than 7% of municipalities reached that level. Conclusions: The Mais Médicos program has granted medical assistance to these historically overlooked populations. However, it is important to evaluate the mid-and long-term sustainability of this initiative.
Revista Panamericana de Salud Pública, 2018
This is an open access article distributed under the terms of the Creative Commons Attribution-No... more This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.
Saúde em Debate, 2019
RESUMO O acesso à saúde de forma universal e equitativa está preconizado na Constituição Federal ... more RESUMO O acesso à saúde de forma universal e equitativa está preconizado na Constituição Federal de 1988, devendo ser garantida pelo Sistema Único de Saúde (SUS). Dentre os diversos fatores que contribuem para a não efetivação dos princípios do SUS, destacam-se a insuficiência de profissionais e as disparidades regionais na distribuição de recursos humanos, principalmente médicos. Este artigo relata a experiência de avaliação do Programa Mais Médicos (PMM) por uma equipe multidisciplinar composta por 28 pesquisadores, a partir de trabalho de campo em 32 municípios com 20% ou mais da população em extrema pobreza selecionados em todas as regiões do Brasil (áreas remotas, distantes das capitais e comunidades quilombolas rurais), além de análises sobre os 5.570 municípios brasileiros baseadas em bancos de dados do Ministério da Saúde. A pesquisa resultou em vasta produção científica, apontando importantes resultados, como ampliação do acesso à saúde e redução de internações evitáveis. A...
Trends in psychiatry and psychotherapy
Factor analysis of the Edinburgh Postnatal Depression Scale (EPDS) could result in a shorter and ... more Factor analysis of the Edinburgh Postnatal Depression Scale (EPDS) could result in a shorter and easier to handle screening tool. Therefore, the aim of this study was to check and compare the metrics of two different 6-item EPDS subscales. We administered the EPDS to a total of 3,891 women who had given birth between 1 and 3 months previously. We conducted confirmatory and exploratory factor analyses and plotted receiver-operating characteristics (ROC) curves to, respectively, determine construct validity, scale items' fit to the data, and ideal cutoff scores for the short versions. A previously defined 6-item scale did not exhibit construct validity for our sample. Nevertheless, we used exploratory factor analysis to derive a new 6-item scale with very good construct validity. The area under the ROC curve of the new 6-item scale was 0.986 and the ideal cutoff score was ≥ 6. The new 6-item scale has adequate psychometric properties and similar ROC curve values to the10-item vers...
Bulletin of the World Health Organization, 2017
Revista brasileira de epidemiologia = Brazilian journal of epidemiology
To identify factors associated with breastfeeding in the first hour of life. A cross-sectional st... more To identify factors associated with breastfeeding in the first hour of life. A cross-sectional study conducted among mothers and children under one year of age, who attended the second stage of the polio vaccination campaign in the Federal District, Brazil, in 2011. The sample was composed of 1,027 pairs of mothers and children. Breastfeeding in the first hour of life was considered as the dependent variable; and the independent variables were: socio-demographic characteristics of the mother, prenatal, delivery and postpartum care, reference to physical or verbal violence/neglect during delivery, and children health. Unadjusted and adjusted prevalence ratios (PR) were used as measures of association, calculated by Poisson regression. The prevalence of breastfeeding in the first hour of life was 77.3%. Inadequate prenatal care (PR = 0.72), cesarean section (PR = 0.88) and no access to rooming-in after birth (PR = 0.28) were factors that interfered negatively in breastfeeding in the f...
Revista brasileira de epidemiologia = Brazilian journal of epidemiology
The article assessed the overall mortality in Brazil in 2000 and 2010. Data source was the Mortal... more The article assessed the overall mortality in Brazil in 2000 and 2010. Data source was the Mortality Information System from Ministry of Health of Brazil. The data show the high rate of mortality among men compared to women between ages of 20 to 59 years and an expressive lower life expectancy by this population. The main groups of death were: external causes; diseases of the circulatory system, diseases of the digestive system, infectious and parasitic diseases, diseases of the respiratory system; mental and behavioral disorders; diseases of the nervous system; endocrine, nutritional and metabolic diseases; neoplasia and diseases of the genitourinary system. Unequal gender relations and distinct characteristics of exposure to risk factors can explain this mortality, highlighting the need to bring critical incorporation of relational gender perspective by public health policies.
PLoS neglected tropical diseases, Aug 1, 2016
Cryptococcus neoformans and Cryptococcus gattii are responsible globally for almost one million c... more Cryptococcus neoformans and Cryptococcus gattii are responsible globally for almost one million cryptococcosis cases yearly, mostly in immunocompromised patients, such as those living with HIV. Infections due to C. gattii have mainly been described in tropical and subtropical regions, but its adaptation to temperate regions was crucial in the species evolution and highlighted the importance of this pathogenic yeast in the context of disease. Cryptococcus gattii molecular type VGII has come to the forefront in connection with an on-going emergence in the Pacific North West of North America. Taking into account that previous work pointed towards South America as an origin of this species, the present work aimed to assess the genetic diversity within the Brazilian C. gattii VGII population in order to gain new insights into its origin and global dispersal from the South American continent using the ISHAM consensus MLST typing scheme. Our results corroborate the finding that the Brazili...
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Papers by Wallace Dos Santos