When maintenance of tooth in a vital condition is no longer possible, the traditional treatment p... more When maintenance of tooth in a vital condition is no longer possible, the traditional treatment philosophy advocates endodontic treatment to retain it in a functional state. A paradigm shift of this thinking occurred with revascularization/regenerative procedures. Dental pulp is a specialized tissue organized in an order spatial arrangement and regenerating it is somewhat exigent. With advancements in molecular science and tissue engineering, the approach is becoming being refined with higher success rates. This review article will detail some of the methods of regeneration and the challenges to achieve success in these procedures.
Aims and Objectives: The present study is aimed to evaluate the biocompatibility of two new resin... more Aims and Objectives: The present study is aimed to evaluate the biocompatibility of two new resin-based root canal sealer materials, i.e., Epiphany sealer and RoekoSeal and to compare their biocompatibility with a commonly used resin based AH plus sealer. After implantation in a subcutaneous tissue of rats and to observe local tissue reaction, at different time periods of 10 days and 90 days. Materials and Methods: Twenty Wistar rats were divided into 2 groups of 10 each for observation after completion of 10 and 90 days following implantation, respectively. Polyethylene tubes loaded with experimental sealer and empty tube (control) were implanted subcutaneously. The subcutaneous tissues from sacrificed rats were analyzed histologically for inflammatory response and were graded with score 0–4. Results were analyzed statistically with Kruskal–Wallis tests. Results: In this study, there are significant differences in the severity of local tissue response to AH plus, Epiphany, and Roek...
International Journal of Preventive and Clinical Dental Research, 2016
Context: Etching of dentin results in demineralization and activation of the dormant matrix metal... more Context: Etching of dentin results in demineralization and activation of the dormant matrix metalloproteinases (MMPs). If the dentin bonding agent subsequently applied fails to penetrate the full depth of this demineralized zone, their collagenolytic effect results in deterioration of the resin-dentin bond over time. Anti-MMP agents like chlorhexidine (CHX) have a potential role in preventing this degradation. Aim: To evaluate the effect of 2% CHX as a rewetting agent on the bond strength of direct composite restoration to dentin. Settings and design: In vitro study. Materials and methods: Superficial dentin of the samples was exposed, etched, and divided into two groups. Group I specimens were rewet with water while CHX was used in group II. Composite cylinders of uniform dimension were built up and the specimens were subjected to shear bond strength testing immediately (at 24 hours) and after 6 months. Statistical analysis: Independent t-test to determine whether differences if present were significant. Results: Although the immediate shear bond strength values were higher for the CHX group, the difference was not statistically significant. After 6 months, the higher shear bond strength values were obtained for the CHX group and the difference was statistically significant. Conclusion: Rewetting with 2% CHX has a beneficial effect on the resin-dentin bond over a 6-month storage period.
Conservative Dentistry and Endodontic Journal, 2016
Traumatic injuries of the teeth and their structures are complex and require comprehensive examin... more Traumatic injuries of the teeth and their structures are complex and require comprehensive examination, accurate diagnosis, consideration of various factors involved and a multidisciplinary approach for successful treatment outcome. Dental trauma, in which the fracture line originates in the crown portion of the tooth, extends apically into the root in an oblique direction is referred to as a crown-root fracture. Subgingival fracture of a tooth presents a challenging restorative problem and needs efficient assessment for treatment. A fractured tooth presents a multifaceted problem which warrants a multidisciplinary treatment. A fractured tooth presents a multifaceted problem which warrants a multidisciplinary treatment. Interdisciplinary treatment approach holds true especially in multifaceted problems like traumatic tooth fracture. Every dental professional must be prepared to assess and treat efficiently.
When maintenance of tooth in a vital condition is no longer possible, the traditional treatment p... more When maintenance of tooth in a vital condition is no longer possible, the traditional treatment philosophy advocates endodontic treatment to retain it in a functional state. A paradigm shift of this thinking occurred with revascularization/regenerative procedures. Dental pulp is a specialized tissue organized in an order spatial arrangement and regenerating it is somewhat exigent. With advancements in molecular science and tissue engineering, the approach is becoming being refined with higher success rates. This review article will detail some of the methods of regeneration and the challenges to achieve success in these procedures.
Aims and Objectives: The present study is aimed to evaluate the biocompatibility of two new resin... more Aims and Objectives: The present study is aimed to evaluate the biocompatibility of two new resin-based root canal sealer materials, i.e., Epiphany sealer and RoekoSeal and to compare their biocompatibility with a commonly used resin based AH plus sealer. After implantation in a subcutaneous tissue of rats and to observe local tissue reaction, at different time periods of 10 days and 90 days. Materials and Methods: Twenty Wistar rats were divided into 2 groups of 10 each for observation after completion of 10 and 90 days following implantation, respectively. Polyethylene tubes loaded with experimental sealer and empty tube (control) were implanted subcutaneously. The subcutaneous tissues from sacrificed rats were analyzed histologically for inflammatory response and were graded with score 0–4. Results were analyzed statistically with Kruskal–Wallis tests. Results: In this study, there are significant differences in the severity of local tissue response to AH plus, Epiphany, and Roek...
International Journal of Preventive and Clinical Dental Research, 2016
Context: Etching of dentin results in demineralization and activation of the dormant matrix metal... more Context: Etching of dentin results in demineralization and activation of the dormant matrix metalloproteinases (MMPs). If the dentin bonding agent subsequently applied fails to penetrate the full depth of this demineralized zone, their collagenolytic effect results in deterioration of the resin-dentin bond over time. Anti-MMP agents like chlorhexidine (CHX) have a potential role in preventing this degradation. Aim: To evaluate the effect of 2% CHX as a rewetting agent on the bond strength of direct composite restoration to dentin. Settings and design: In vitro study. Materials and methods: Superficial dentin of the samples was exposed, etched, and divided into two groups. Group I specimens were rewet with water while CHX was used in group II. Composite cylinders of uniform dimension were built up and the specimens were subjected to shear bond strength testing immediately (at 24 hours) and after 6 months. Statistical analysis: Independent t-test to determine whether differences if present were significant. Results: Although the immediate shear bond strength values were higher for the CHX group, the difference was not statistically significant. After 6 months, the higher shear bond strength values were obtained for the CHX group and the difference was statistically significant. Conclusion: Rewetting with 2% CHX has a beneficial effect on the resin-dentin bond over a 6-month storage period.
Conservative Dentistry and Endodontic Journal, 2016
Traumatic injuries of the teeth and their structures are complex and require comprehensive examin... more Traumatic injuries of the teeth and their structures are complex and require comprehensive examination, accurate diagnosis, consideration of various factors involved and a multidisciplinary approach for successful treatment outcome. Dental trauma, in which the fracture line originates in the crown portion of the tooth, extends apically into the root in an oblique direction is referred to as a crown-root fracture. Subgingival fracture of a tooth presents a challenging restorative problem and needs efficient assessment for treatment. A fractured tooth presents a multifaceted problem which warrants a multidisciplinary treatment. A fractured tooth presents a multifaceted problem which warrants a multidisciplinary treatment. Interdisciplinary treatment approach holds true especially in multifaceted problems like traumatic tooth fracture. Every dental professional must be prepared to assess and treat efficiently.
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Papers by Vivek Chand