Recent advances in functionalized organic Spiro heterocyclic compounds composed of nitrogen bonde... more Recent advances in functionalized organic Spiro heterocyclic compounds composed of nitrogen bonded five- and six-membered rings have been made, establishing them as a synthetic target in organic-based biomedical applications. In this work, we report a synthesis of spirocyclic compounds under a one-pot reaction using 1,3-dipolar cycloaddition in a regio and diastereoselective manner. The higher atomic economy with higher yield (95%) and regio and stereoselectivity were achieved by a multi-component reaction of L-proline (1), Indenoquinoxaline (2), and the dipolarophile of malononitrile (3) solvents followed by reflux conditions. The reaction intermediate comprised azomethineylides derived from reactive primary amines, and the spiro derivatives were synthesized up to a ≈ 95% yield. The structural and characteristic chemical components of the as-prepared Spiro compounds were characterized by 1H-NMR, FTIR, and Mass spectroscopy. The functionalized spiro-pyrrolizidines were found to be e...
International Journal of Applied Nanotechnology Research, 2020
Fly ash is considered one of the major hazardous pollutants around the globe. Every year a millio... more Fly ash is considered one of the major hazardous pollutants around the globe. Every year a million tonnes of fly ash is disposed of into the fly ash ponds which are major sites of pollution. The major fractions of fly ash are silicates, aluminates, and ferrous substances followed by minor traces element oxides. The aluminates and silicates comprise of 70% of the fly ash. The aluminates and silicates are present in fly ash in the form of crystalline mullites and sillimanites. Mullites being inert and crystalline are retractile to mineral acids. So, here the authors have reported a novel and simple step for the recovery of all the major elements of fly ash along with recovery of mullites by using hydrofluoric acid at room temperature. The method comprises of treatment of fly ash with diluted hydrofluoric acid for 12 hours under agitation. The recovered white color mullite powder, rod shaped of size 90-300 nm, was analyzed by the sophisticated instruments for the confirmation of the mu...
Cutting-edge technologies are making inroads into new areas and this remarkable progress has been... more Cutting-edge technologies are making inroads into new areas and this remarkable progress has been successfully influenced by the tiny level engineering of carbon dots technology, their synthesis advancement and impressive applications in the field of allied sciences. The advances of science and its conjugation with interdisciplinary fields emerged in carbon dots making, their controlled characterization and applications into faster, cheaper as well as more reliable products in various scientific domains. Thus, a new era in nanotechnology has developed into carbon dots technology. The understanding of the generation process, control on making processes and selected applications of carbon dots such as energy storage, environmental monitoring, catalysis, contaminates detections and complex environmental forensics, drug delivery, drug targeting and other biomedical applications, etc., are among the most promising applications of carbon dots and thus it is a prominent area of research to...
Recent advances in functionalized organic Spiro heterocyclic compounds composed of nitrogen bonde... more Recent advances in functionalized organic Spiro heterocyclic compounds composed of nitrogen bonded five- and six-membered rings have been made, establishing them as a synthetic target in organic-based biomedical applications. In this work, we report a synthesis of spirocyclic compounds under a one-pot reaction using 1,3-dipolar cycloaddition in a regio and diastereoselective manner. The higher atomic economy with higher yield (95%) and regio and stereoselectivity were achieved by a multi-component reaction of L-proline (1), Indenoquinoxaline (2), and the dipolarophile of malononitrile (3) solvents followed by reflux conditions. The reaction intermediate comprised azomethineylides derived from reactive primary amines, and the spiro derivatives were synthesized up to a ≈ 95% yield. The structural and characteristic chemical components of the as-prepared Spiro compounds were characterized by 1H-NMR, FTIR, and Mass spectroscopy. The functionalized spiro-pyrrolizidines were found to be e...
International Journal of Applied Nanotechnology Research, 2020
Fly ash is considered one of the major hazardous pollutants around the globe. Every year a millio... more Fly ash is considered one of the major hazardous pollutants around the globe. Every year a million tonnes of fly ash is disposed of into the fly ash ponds which are major sites of pollution. The major fractions of fly ash are silicates, aluminates, and ferrous substances followed by minor traces element oxides. The aluminates and silicates comprise of 70% of the fly ash. The aluminates and silicates are present in fly ash in the form of crystalline mullites and sillimanites. Mullites being inert and crystalline are retractile to mineral acids. So, here the authors have reported a novel and simple step for the recovery of all the major elements of fly ash along with recovery of mullites by using hydrofluoric acid at room temperature. The method comprises of treatment of fly ash with diluted hydrofluoric acid for 12 hours under agitation. The recovered white color mullite powder, rod shaped of size 90-300 nm, was analyzed by the sophisticated instruments for the confirmation of the mu...
Cutting-edge technologies are making inroads into new areas and this remarkable progress has been... more Cutting-edge technologies are making inroads into new areas and this remarkable progress has been successfully influenced by the tiny level engineering of carbon dots technology, their synthesis advancement and impressive applications in the field of allied sciences. The advances of science and its conjugation with interdisciplinary fields emerged in carbon dots making, their controlled characterization and applications into faster, cheaper as well as more reliable products in various scientific domains. Thus, a new era in nanotechnology has developed into carbon dots technology. The understanding of the generation process, control on making processes and selected applications of carbon dots such as energy storage, environmental monitoring, catalysis, contaminates detections and complex environmental forensics, drug delivery, drug targeting and other biomedical applications, etc., are among the most promising applications of carbon dots and thus it is a prominent area of research to...
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Papers by Virendra Yadav