Papers by Vasilios Souftas
Objetivo. Como parte del tratamiento de la Diabetes Mellitus 2 (DM 2) no solo esta implicado el t... more Objetivo. Como parte del tratamiento de la Diabetes Mellitus 2 (DM 2) no solo esta implicado el tratamiento farmacologico sino tambien el ajuste de la dieta alimenticia, el control del peso y el desarrollo de actividades fisicas. El objetivo de este estudio fue estimar el nivel de adherencia al tratamiento farmacologico y dietetico, teniendo en cuenta la relacion existente con la edad, el sexo, el grado de instruccion y el control de glicemia. Material y Metodo. Se realizo un estudio transversal descriptivo en 124 pacientes pertenecientes al programa de Diabetes del Policlinico Chiclayo Oeste – EsSalud en diciembre del 2015, el muestreo fue probabilistico y se conto con la autorizacion de las autoridades del Policlinico y del medico tratante, el analisis estadistico fue mediante Software Excel 2013. Resultados. De un total de 124 encuestados, el 35,48% presento adherencia farmacologica, y el 33,87% adherencia dietetica. Ademas el 47,58% reflejo control de la enfermedad teniendo como...
Radiation dose to the genitalia of women undergoing uterine artery embolization for the treatment of symptomatic myomatosis and adenomyosis
Poster: "ECR 2010 / C-2930 / Radiation dose to the genitalia of women undergoing uterine art... more Poster: "ECR 2010 / C-2930 / Radiation dose to the genitalia of women undergoing uterine artery embolization for the treatment of symptomatic myomatosis and adenomyosis" by: "I. Abatzoglou, V. D. Souftas, I. Tsalafoutas, E. Astrinakis, M. Mantatzis, P. Prassopoulos; Alexandroupolis/GR"
Computed-Tomography-Guided Direct Percutaneous Transhepatic Embolization of a Bleeding Hepatic Artery Branch Aneurysm
Acta Radiologica, 2006
A case of successful direct percutaneous transhepatic coil embolization of a ruptured intrahepati... more A case of successful direct percutaneous transhepatic coil embolization of a ruptured intrahepatic aneurysm under computed tomography (CT) guidance is presented. The patient had a history of multiple operations for liver echinococcosis and was transferred to the emergency department in a deteriorating clinical condition due to active hemorrhage. The aneurysm was treated with percutaneous transhepatic embolization under CT guidance. The procedure is not time-consuming and keeps the time interval between diagnosis and treatment to a minimum, thereby limiting subsequent blood loss.
Journal of the Hellenic Veterinary Medical Society
A four-year old Rottweiler was presented with tetraplegia, established progressively over a 4-mon... more A four-year old Rottweiler was presented with tetraplegia, established progressively over a 4-month period. Initiallythe dog developed paresis of the posterior limbs that subsequently evolved to tetraparesis and finally tetraplegia. Upon neurological examination the dog exhibited spastic tetraplegia with exaggerated spinal reflexes in all four limbs. The neuroanatomical lesion localization indicated a focal or diffuse cervical spinal cord disease. Cisternal myelography revealed obstruction of the contrast medium flow at the level of C5 vertebral body. Magnetic resonance imaging disclosed intradural-extramedullary compression of the spinal cord at the level of C5-C6 intervertebral disc by a spinal arachnoid pseudocyst, syrinx formation and myelopathy expressed as abnormally higher signal on T2-weighted images at the C5 segment level. Severe demyelination, involving exclusively the white matter of the grossly affected segments and extending rostrally into the brainstem and caudally in...
Vascular, 2015
Purpose To present a case of inadvertent collapse of the contralateral limb gate caused by misori... more Purpose To present a case of inadvertent collapse of the contralateral limb gate caused by misorientation during the deployment of the Ovation Abdominal Stent Graft System in a narrow aortic lumen and the bailout conversion to aortouniiliac modification, using a covered stent to exclude the orifice of the internal iliac artery (IIA). Technique description Despite the repeated efforts from the femoral and brachial site, the collapsed/occluded contralateral limb gate could not be catheterized. In order to exclude successfully the orifice of the IIA, an oversized stentgraft was placed immediately at the common-to-external iliac artery (CIA-EIA) transition followed by peripheral ligation of the latter. The procedure was completed with crossover femorofemoral bypass. Conclusion Occlusion the IIA orifice with an oversized stentgraft in the CIA-EIA transition can be considered as a safe, simple, fast, and efficient bailout maneuver, followed by EIA ligation and crossover bypass.
Gastroenterology research and practice, 2015
Aim. To evaluate the feasibility of percutaneous sclerotherapy of symptomatic simple abdominal cy... more Aim. To evaluate the feasibility of percutaneous sclerotherapy of symptomatic simple abdominal cysts, using hypertonic saline and bleomycin, as an alternative to surgery. Materials and Methods. This study involved fourteen consecutive patients (ten women, four men, mean age: 59.2 y) with nineteen symptomatic simple cysts (liver n = 14, kidney n = 3, and adrenal n = 2) treated percutaneously using a modified method. Initially CT-guided drainage was performed; the next day the integrity of the cyst/exclusion of extravasation or communications was evaluated under fluoroscopy, followed by two injections/reabsorptions of the same quantity of hypertonic NaCl 15% solution and three-time repetition of the same procedure with the addition of bleomycin. The catheter was then removed; the patients were hospitalized for 12 hours and underwent follow-ups on 1st, 3rd, 6th, and 12th months. Cyst's volumes and the reduction rate (%) were calculated in each evaluation. Results. No pain or compli...
European Journal of Vascular and Endovascular Surgery, 2007
A case report is presented of a IEA false aneurysm successfully embolized in a 50-year old man fo... more A case report is presented of a IEA false aneurysm successfully embolized in a 50-year old man following a blunt abdominal injury. A literature review revealed another 15 cases. Most cases were iatrogenic (13/16) complicating abdominal wall procedures. Treatment options included open surgery (8 cases), percutaneous coil embolization (6), ultrasound guided thrombin injection or ultrasound guided compression (2). The selected treatment (surgical or non-surgical) was not affected by the size of the aneurysm (p ¼ 0.6) and was successful in all patients. However two of the non-surgically removed lesions (25%) remained unchanged in size for a long time causing discomfort. IEA false aneurysms represent an uncommon entity. Open surgery for IEA false aneurysms is easy and cheap. Endovascular approaches can lead to a long delay in resolution of the problem.
Reversible Posterior Leukoencephalopathy Syndrome Induced by Pazopanib
BMC Cancer, 2012
Maturitas, 2009
postmenopausal women recent users of CCHRT. Methods: There were 63 women, aged 50-58 years, compl... more postmenopausal women recent users of CCHRT. Methods: There were 63 women, aged 50-58 years, complaining of the uterine bleeding during the early postmenopausal period (up to 5 years). They were divided in two groups: in the first group of patients there were recent users of CCHRT, using HRT for 18-24 months, started during the first postmenopausal year; average age was 54,8 years. In the second group there were women never users of HRT; average age of this group was 56,2 years. All women were undergone to explorative curettage. Results: In the first group of patients, endometrial hyperplasia was discovered average 24,7 months after stopping with HRT. There were 78,3% patients with hyperplasia simplex and 21,7% with hyperplasia complex. In the second group, endometrial hyperplasia was diagnosed average 32,4 months after the last menstrual period. There were 84,7% patients with hyperplasia simplex and 15,3% patients with hyperplasia complex. Conclusions: Early postmenopausal women, past but recent users of CCHRT, developed earlier and in the higher rate endometrial hyperplasia with higher rate of hyperplasia complex, in comparision with women never users of HRT.
Bone mineral density in adults with Down's syndrome
European Radiology, 1999
. The objective of the study was to elucidate if individuals with Down's syndrome (DS) are... more . The objective of the study was to elucidate if individuals with Down's syndrome (DS) are likely to experience an increased risk of osteoporosis with advancing age, in addition to precocious aging and their skeletal anomalies. Bone mineral density (BMD) was measured in 22 home-reared adults (9 males and 13 females; age 26.22 ± 4.45 and 23.65 ± 3.23 years, respectively) by dual energy X-ray absorptiometry (DXA). The BMD of the second to fourth lumbar vertebrae was measured in posteroanterior projection and the mean density expressed as grams per square centimetre. The BMD of DS individuals was compared with 27 control subjects (12 males and 15 females) of the same age (age 24.16 ± 3.46 and 23.86 ± 2.92 years, respectively). The results showed that the BMD of the lumbar spine in the males as well as in the females with DS was significantly lower than that in their control counterparts (p < 0.001). Comparing the DS males with the females, the BMD was lower in the males at a level of 9 %. Factors that contribute to this disorder may be mainly the muscular hypotonia, the sedentary lifestyle and the accompanying diseases which frequently observed in the syndrome. Future studies must be focused on the biochemistry of bone metabolism, the evaluation of gonadal, thyroid and parathyroid function, and the genes of the extra chromosome 21.
Gastroenterology research and practice, 2012
Background/Objectives. Pancreatitis remains the most common complication of ERCP. History of post... more Background/Objectives. Pancreatitis remains the most common complication of ERCP. History of post-ERCP pancreatitis is an independent risk factor for a new episode, suggesting a genetic background. The N34S mutation in serine protease inhibitor Kazal type 1 (SPINK 1) gene may downregulate the threshold for the development of pancreatitis. The aim of the present study is to evaluate the presence of this mutation among patients with post-ERCP pancreatitis. Methods. During a period of four years, thirty patients with post-ERCP pancreatitis entered the study. Patients and procedural data were collected, focusing on risk factors for pancreatitis. Blood samples were taken for genetic testing for the presence of N34S mutation in SPINK 1 gene. After DNA extraction, we used an allele-specific polymerase chain reaction as an initial screening method for the N34S mutation, and in order to confirm the results and to determine the hetero- and homozygosity genotype status, we used a restriction f...
Complete response after sorafenib therapy for hepatocellular carcinoma in an HIV-HBV co infected patient: Possible synergy with HAART ? A case report
Medical oncology (Northwood, London, England), 2011
A significant proportion of HIV patients, ranging between 5-67%, are co-infected with hepatitis B... more A significant proportion of HIV patients, ranging between 5-67%, are co-infected with hepatitis B virus (HBV). Several studies suggest an increasing incidence of hepatocellular carcinoma (HCC) in HIV infected individuals. We report the case of a 69 years old male co infected with HBV and HIV who developed HCC. The patient was unfit for curative approach and he underwent three sessions of transcatheter arterial chemoembolisation (TACE). After the last session the disease assessment showed progression and sorafenib therapy was initiated. Highly active antiretroviral therapy (HAART) was continued during sorafenib treatment. The patient achieved a radiological complete response (CR) after 6 months of therapy and remained with no sign of HCC progression at subsequent assessment. Meanwhile, patient's HIV and HBV infections remained stable. Regarding toxicity the patient developed grade 3 hand foot skin reaction (HFSR) that required 50% dose reduction of sorafenib, grade 3 hypertension...
Reversal of deep vein reflux after successful stenting in a patient with venous hypertension after thigh access graft creation
Vascular and endovascular surgery
Presented here is a case of reversal of deep vein reflux after successful stenting in a patient w... more Presented here is a case of reversal of deep vein reflux after successful stenting in a patient with venous hypertension and valve incompetence after thigh angioaccess creation. The patient with exhausted upper-extremity access sites underwent a loop graft in the upper thigh. Six months later, the patient developed leg edema and significant femoral vein reflux on duplex ultrasound. Fistulography revealed an iliac vein stenosis, which was treated successfully with stenting. The edema and reflux on duplex promptly resolved. In similar cases, reflux may be a consequence of functional valve incompetence and can be reverted by timely treating the underlying stenosis.
Urological Research, 2009
We report the case of a male patient with a left renal pelvic stone 2.5 cm in maximum diameter an... more We report the case of a male patient with a left renal pelvic stone 2.5 cm in maximum diameter and a large upper pole intrarenal arterial aneurysm on the same side. The stone was treated with percutaneous nephrolithotomy (PCNL). This procedure was feasible even in this diYcult clinical setting. Puncture of a calyx located at a safe distance from the aneurysm and meticulous surgical technique were essential in realizing the best possible outcome. To our knowledge, this is the Wrst case of PCNL performed on a patient with a renal stone and an intrarenal arterial aneurysm.
Journal of Veterinary Medicine Series A, 2004
Ten dogs with primary (n ¼ 8) and metastatic (n ¼ 2) brain tumours were studied in an attempt to ... more Ten dogs with primary (n ¼ 8) and metastatic (n ¼ 2) brain tumours were studied in an attempt to evaluate the diagnostic sensitivity of computed tomography (CT) or magnetic resonance imaging (MRI). Of the clinical signs noticed, seizures (seven of 10), behavioural abnormalities and cognition dysfunction (seven of 10), compulsive walking and circling (six of 10), sensorimotor (five of 10) and neuro-opthalmological (two of 10) dysfunction were the most common. In all 10 animals that finally died of the disease or were killed, the histopathological diagnosis that followed necropsy was taken as a golden standard in the CT or MRI prediction of the histological type of brain neoplasms. In every instance, tumour detection, morphology and histological differentiation were possible with the aid of either CT (seven of 10) or MRI (three of 10) imaging especially after contrast enhancement. Only one CT-evaluated dog, diagnosed as meningioma, was found to be astrocytoma on histopathology. Interestingly, a rare case of cerebellar medulloblastoma was correctly identified in MRI scans.
Unusual Malpositioning of Hemodialysis Catheter into the Hepatic Veins
Renal Failure, 2012
Malpositioning of long-term hemodialysis catheter is a known complication that may lead to a grad... more Malpositioning of long-term hemodialysis catheter is a known complication that may lead to a gradual decline in blood flow. We report two rare catheter malpositions in the hepatic veins in two patients with end-stage renal disease in whom a dialysis catheter was inserted through the left external jugular vein and the right external jugular vein. Because of gradual reduction of catheters&amp;amp;amp;amp;amp;amp;#39; blood flow, an angiography was performed, which confirmed catheters&amp;amp;amp;amp;amp;amp;#39; tip positioning into the hepatic veins. The catheters were replaced in the correct site.
Journal of Surgical Research, 2008
Background. Radiofrequency ablation (RFA) of the liver leads to reduction of liver parenchymal vo... more Background. Radiofrequency ablation (RFA) of the liver leads to reduction of liver parenchymal volume. We sought to evaluate the regenerative response of the liver following RFA.
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2002
Objective: The objective of the study was to find out whether biochemical and hormonal profile of... more Objective: The objective of the study was to find out whether biochemical and hormonal profile of sexual function and mineral metabolism are related to low bone mass in young men with Down syndrome. Study design: Eleven young men with trisomy 21 (mean age 26.45 years) and 12 healthy university students of similar age, participated in the study. The bone mineral density (BMD) of the lumbar vertebrae was measured in posteroanterior (PA) projection. Sexual development was assessed by clinical examination. The levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone, dehydroepiandrosterone sulfate (DHEA-S), 17-OH progesterone and parathormone (PTH) were measured accordingly by radioimmunoassay. Serum calcium (Ca) and phosphate (P) as well as fasting urinary Ca and hydroxyproline (OHP) were also measured. Results: BMD in DS patients was significantly lower (P < 0:001) compared to their control counterparts. No significant differences were observed in mean concentrations of FSH, testosterone and DHEA-S, while LH and 17-OH progesterone levels were significantly higher in DS compared to control group (P < 0:01 and <0.05, respectively). Serum Ca and P and urine Ca/Creat ratio did not differ between groups. OHP/Creat ratio was significantly higher in DS patients. PTH levels were extremely low (1 pmol/l) in two patients. Conclusions: The findings of this study show decreased bone mass in subjects with DS. Factors, possibly related to low bone mass, are some degree of hypogonadim, hypotonia, low muscular strength and immobility. The findings suggest further research on the biochemistry and endocrinology of bone metabolism in patients with trisomy 21. #
Cases Journal, 2009
Toothpick ingestion is implicated in gut injuries which may cause severe complications, mimicking... more Toothpick ingestion is implicated in gut injuries which may cause severe complications, mimicking diseases causing acute abdomen. However, toothpick ingestion-related perforation may also cause mild, non-specific gastrointestinal symptoms without significant findings or major complications. We describe a young male with chronic postprandial lower abdominal pain caused by a toothpick impaction at the rectosigmoid junction after inadvertent ingestion. The foreign body was detected and successfully removed during flexible sigmoidoscopy. Perforation due to foreign body ingestion must be considered in the differential diagnosis in patients presenting with unexplained symptoms and findings, even when they do not recall any foreign body ingestion.
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Papers by Vasilios Souftas