Papers by Valikapathalil Kurian
Asian Cardiovascular and Thoracic Annals
Indian Journal of Thoracic and Cardiovascular Surgery
Indian Heart …, 2003
Heart-lung transplantation is a well accepted and standard form of therapy for the surgical manag... more Heart-lung transplantation is a well accepted and standard form of therapy for the surgical management of patients with end-stage cardiopulmonary disorders. The first heart-lung transplant in India was performed at our institution on May 3, 1999 and, subsequently, 2 more patients have ...
Results: Commonest mediastinal mass was of thymic origin followed by neurogenic, germ cells and o... more Results: Commonest mediastinal mass was of thymic origin followed by neurogenic, germ cells and others. Tissue or origin of the masses are : Thymic 32 cases, Lymphatics 13 cases, Mesenchymal (Dermoid) 17 cases, Bronchial Cyst 2 cases and Neurogenic 23 cases. There were 4 mortaity in our series 3 were of thymic origin and one was of huge dermoid. Conclusions: Mediastinal mass was not as rare as it is thought to be. Majority are asymtomatic. Commonest mediastinal mass was of thymic origin and an aggressive surgical approach gives gratifying results.
Indian heart journal
Myocardial Infarction (MI) hampers cardiac performance by ventricular remodeling which is a major... more Myocardial Infarction (MI) hampers cardiac performance by ventricular remodeling which is a major cause of heart failure or death. Conventional drug therapies like beta blockers, angiotensin-converting enzyme may delay remodeling but there is no single therapeutic regimen available that can prevent or reverse the process of myocardial injury. Interventional therapies and surgical procedures improve or normalize coronary blood flow greatly. Experimental data suggests that bone marrow derived Mesenchymal Stem Cells (MSCs) may contribute to the healing of Myocardial infarction. We present our findings on the use of bone marrow derived MSCs for Myocardial Infarction wherein the cells were injected in and around the infarct region epicardially during coronary bypass surgery. 31 patients selected to undergo Coronary Artery Bypass Graft (CABG) as a treatment option for myocardial infarction formed the subject matter of our study. One patient withdrew consent before receiving our therapy an...
The Journal of cardiovascular surgery, 2002
A case of invasive pulmonary aspergillosis in a 33-year-old, non-immunocompromised male presentin... more A case of invasive pulmonary aspergillosis in a 33-year-old, non-immunocompromised male presenting with lower limb paraplegia is reported. The clinical manifestations, diagnosis, and combined medical and surgical management of this rare condition are described.
Polymer Journal, 2013
ABSTRACT Colonization of bacteria around native host cells or polymeric implant surfaces results ... more ABSTRACT Colonization of bacteria around native host cells or polymeric implant surfaces results in a dense growth on the surface, which leads to infection. The change of a bacterium from a motile planktonic to a nonmotile long chain of growing cells is a complex, regulated process that depends on several factors. The probability of a biofilm-related infection occurrence is between 65 and 80%. This review critically evaluates the mode of biofilm formation on native tissues and orthopedics, dental, cardiac, and urological implants and vascular grafts. The combination of biochemical advancements with conventional microbiological techniques and the use of radio-labeled monoclonal antibodies in imaging techniques, with recent developments in the detection of these biofilm in vivo, would help in designing biomaterials that prevent bacterial adhesion and biofilm formation, and dislodge the formed biofilm, thereby accelerating the product development phase.
Indian Journal of Thoracic and Cardiovascular Surgery, 2004
Our experience with aortic root replacement using [----] hand-sewn composite valve graft 11311 Na... more Our experience with aortic root replacement using [----] hand-sewn composite valve graft 11311 Nageaajan M,
Indian Journal of Thoracic and Cardiovascular Surgery, 2004
This study was undertaken to establish the variability in levels of lipid profiles between the wo... more This study was undertaken to establish the variability in levels of lipid profiles between the women who underwent CABG with endarterectomy and without endarterectomy.
Indian heart journal
A 57-year-old male underwent coronary angiography for exertional angina which showed two left ant... more A 57-year-old male underwent coronary angiography for exertional angina which showed two left anterior descending coronary arteries (LAD)--a short LAD from the left coronary sinus terminating in the proximal Anterior Inter-Ventricular Sulcus (AIVS), a long LAD from the proximal right coronary artery entering the distal AIVS and an anomalous left circumflex artery from the right coronary sinus. In addition, he also had absent right superior vena cava and a persistent left superior vena cava entering the coronary sinus.
The Journal of cardiovascular surgery, 2002
A case of invasive pulmonary aspergillosis in a 33-year-old, non-immunocompromised male presentin... more A case of invasive pulmonary aspergillosis in a 33-year-old, non-immunocompromised male presenting with lower limb paraplegia is reported. The clinical manifestations, diagnosis, and combined medical and surgical management of this rare condition are described.
Indian Journal of Thoracic and Cardiovascular Surgery, 2004
Rajan Modi et al Pectoral and omental flap plasty 1 AUTHORS 1. Rajan Modi M.S 2. Vishwanathan BS ... more Rajan Modi et al Pectoral and omental flap plasty 1 AUTHORS 1. Rajan Modi M.S 2. Vishwanathan BS 3. Suresh Keshavamurthy M.S MCh 4. V.M.Kurian M.S MCh 5. S.Rajan M.S MCh [Type the abstract of the document here. The abstract is typically a short summary of the contents of the document. Type the abstract of the document here. The abstract is typically a short summary of the contents of the document.] Rajan Modi et al Pectoral and omental flap plasty 2 ABSTRACT Objective Mediastinal infection is a rare but life-threatening complication after cardiac surgery. Flap reconstructive procedures have made possible early closure and healing of sternal wounds. This study evaluates the outcome of post-sternotomy mediastinitis managed with pectoralis muscle mobilization and omental transposition. Methods 47 patients with a diagnosis of post-operative mediastinitis underwent either pectoral and/or omental plasty during the last 7 years. 20 patients had both omentum and pectoral muscle plasty, 17 had bilateral pectoral muscle plasty, 3 had pectoral muscle flap turnover and 6 had omentoplasty alone. The greater omentum is dissected based on the right gastro-epiploic artery. Pectoral flaps are raised by releasing the sternocostal origin and dissecting upto the posterior axillary line. All the unhealthy tissues are excised till they bleed freely. Omentum Rajan Modi et al Pectoral and omental flap plasty 3 is placed in the mediastinum and fixed at a few points. If the sternal margins are healthy, it is approximated with delayed absorbable sutures. The pectorals are sutured and the skin is closed with interrupted sutures. Continuous redivac suction drains are placed. A pressure dressing is applied using elasto-crepe bandage. The negative suction drains are removed when the drainage becomes less than 20 ml for 3 consecutive days Results 26 patients underwent procedure in the early post-operative period in the early post-operative period and 21 patients had plasty procedure after discharge (late). 75% were culture positive and 34% of them tested positive for Staphylococcus aureus which was the single largest organism to be cultured. The next largest group was coagulase negative staphylococci (10.6 %).The overall mortality was 15 %. Conclusion Post-operative mediastinitis is a potentially lethal complication following open heart surgery. Early intervention and use of omental and/or pectoral flap has improved our results in the treatment of post-operative mediastinitis. Rajan Modi et al Pectoral and omental flap plasty
Indian Journal of Thoracic and Cardiovascular Surgery, 2011
Background The incidence of Sternal wound infection as reported worldwide is 0.43-2.3% [1-7]. The... more Background The incidence of Sternal wound infection as reported worldwide is 0.43-2.3% [1-7]. The incidence is low and has serious effects on the patients in terms of the morbidity, hospital stay, cost as well as mortality. This study proposes to identify the risk factors, changing bacteriologic and the treatment outcomes. Methods 6492 consecutive patients who had median sternotomy for open heart surgery in the adult unit were retrospectively analysed (using SPSS10.0 window software) between
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Papers by Valikapathalil Kurian