National Center for Educational Research and Development (NCERD)- Egypt
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A Deeper View in the Pathogenesis of Vasomotor Rhinitis
Abstract: Introduction: Vasomotor rhinitis cause nasal symptoms that occur in response to environ... more Abstract: Introduction: Vasomotor rhinitis cause nasal symptoms that occur in response to environmental conditions, such as changes in temperature or relative humidity, odours (e.g., perfumes or cleaning materials), passive tobacco smoke, alcohol, sexual arousal, and emotional factors. Such hyper-reactivity to nonallergic triggers is not mediated by increased neural efferent traffic to the blood vessels supplying the nasal mucosa. It can also occur- in allergic rhinitis, when the term mixed rhinitis is applied. Objectives: The present study aimed to study the pathogenesis of VMR by electron microscopy to see if there is another cause for this disease. Material and Methods: It was a prospective randomised study which was held at Benha Faculty of Medicine, in the period from January 2009 to November 2011. It was conducted on 45 patients divided into two groups. The study was carried out in a group of 39 patients (21 males, 18 females; age range 25- 38 years) with VMR and 6 control pat...
Background: Endoscopic sinus surgery (ESS) has become the treatment of choice for nasal polyposis... more Background: Endoscopic sinus surgery (ESS) has become the treatment of choice for nasal polyposis and chronic rhinosinusitis that cannot be adequately managed with medical therapy. Nasal packing is usually placed after ESS to prevent synechiae formation and postoperative bleeding and to support wound healing. Objectives: This study was done to evaluate the effect of different materials on the formation of synechiae and excessive granulation tissue in the middle meatus in patients who had undergone ESS. Methods: A total of 90 patients who had undergone ESS were studied prospectively. At the end of ESS each patient was packed with one of the three different materials randomly. The outcome variable was the formation of synechiae and excessive granulation tissue in the middle meatus, which was identified from endoscopic evaluations performed 3-4 weeks and 10-12 weeks after surgery. Results: We observed significant intergroup differences in the effect on the formation of synechiae in the middle meatus. The nasopore group was superior to the other two groups and there is a significant reduction in synechiae formation in the nasopore group than both other groups. Conclusion: Among patients who had undergone ESS for rhinosinusitis with or without polyps, the incidence of synechiae and excessive granulation tissue in the middle meatus in the patients who received nasopore packing was less to that of synechiae in the patients who received merocel and mitomycin C.
A Deeper View in the Pathogenesis of Vasomotor Rhinitis
Abstract: Introduction: Vasomotor rhinitis cause nasal symptoms that occur in response to environ... more Abstract: Introduction: Vasomotor rhinitis cause nasal symptoms that occur in response to environmental conditions, such as changes in temperature or relative humidity, odours (e.g., perfumes or cleaning materials), passive tobacco smoke, alcohol, sexual arousal, and emotional factors. Such hyper-reactivity to nonallergic triggers is not mediated by increased neural efferent traffic to the blood vessels supplying the nasal mucosa. It can also occur- in allergic rhinitis, when the term mixed rhinitis is applied. Objectives: The present study aimed to study the pathogenesis of VMR by electron microscopy to see if there is another cause for this disease. Material and Methods: It was a prospective randomised study which was held at Benha Faculty of Medicine, in the period from January 2009 to November 2011. It was conducted on 45 patients divided into two groups. The study was carried out in a group of 39 patients (21 males, 18 females; age range 25- 38 years) with VMR and 6 control pat...
Background: Endoscopic sinus surgery (ESS) has become the treatment of choice for nasal polyposis... more Background: Endoscopic sinus surgery (ESS) has become the treatment of choice for nasal polyposis and chronic rhinosinusitis that cannot be adequately managed with medical therapy. Nasal packing is usually placed after ESS to prevent synechiae formation and postoperative bleeding and to support wound healing. Objectives: This study was done to evaluate the effect of different materials on the formation of synechiae and excessive granulation tissue in the middle meatus in patients who had undergone ESS. Methods: A total of 90 patients who had undergone ESS were studied prospectively. At the end of ESS each patient was packed with one of the three different materials randomly. The outcome variable was the formation of synechiae and excessive granulation tissue in the middle meatus, which was identified from endoscopic evaluations performed 3-4 weeks and 10-12 weeks after surgery. Results: We observed significant intergroup differences in the effect on the formation of synechiae in the middle meatus. The nasopore group was superior to the other two groups and there is a significant reduction in synechiae formation in the nasopore group than both other groups. Conclusion: Among patients who had undergone ESS for rhinosinusitis with or without polyps, the incidence of synechiae and excessive granulation tissue in the middle meatus in the patients who received nasopore packing was less to that of synechiae in the patients who received merocel and mitomycin C.
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Papers by Taha Mohammed